Regulatory T-cell response to enterotoxigenic bacteroides fragilis colonization triggers IL17-dependent colon carcinogenesis

Cancer Discovery

Volumn 5, Issue 10, 2015, Pages 1098-1109

  Geis, Abby L ^a   Fan, Hongni ^a   Wu, Xinqun ^b   Wu, Shaoguang ^b   Huso, David L ^b   Wolfe, Jaime L ^c   Sears, Cynthia L ^a,b,d   Pardoll, Drew M ^a,b   Housseau, Franck ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIPHTHERIA TOXIN; FRAGILYSIN; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR FOXP3;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTEROIDES FRAGILIS; CARCINOGENESIS; COLON CARCINOGENESIS; CONTROLLED STUDY; FLOW CYTOMETRY; INFLAMMATION; MICROADENOMA; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TH17 CELL; TUMOR MICROENVIRONMENT; ANIMAL; BACTEROIDES INFECTION; CELL TRANSFORMATION; COLONIC NEOPLASMS; COMPLICATION; DISEASE MODEL; IMMUNOLOGY; INTESTINE MUCOSA; LYMPHOCYTE DEPLETION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; T LYMPHOCYTE SUBPOPULATION; TRANSGENIC MOUSE;

ANIMALS; BACTEROIDES FRAGILIS; BACTEROIDES INFECTIONS; CELL TRANSFORMATION, NEOPLASTIC; COLONIC NEOPLASMS; DISEASE MODELS, ANIMAL; INTERLEUKIN-17; INTERLEUKIN-2; INTESTINAL MUCOSA; LYMPHOCYTE DEPLETION; MICE; MICE, TRANSGENIC; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84943252054     PISSN: 21598274     EISSN: 21598290     Source Type: Journal    
DOI: 10.1158/2159-8290.CD-15-0447     Document Type: Article

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