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Volumn 466, Issue 3, 2015, Pages 530-535

Ginsenoside Rb1 promotes browning through regulation of PPARγ in 3T3-L1 adipocytes

Author keywords

3T3 L1 adipocytes; Browning; Ginsenoside Rb1; Mitochondrial respiration; PPAR

Indexed keywords

GINSENOSIDE RB 1; PEPTIDES AND PROTEINS; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; RD1 BF1 RIZ1 HOMOLOGOUS DOMAIN CONTAINING 16; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 1; 2-CHLORO-5-NITROBENZANILIDE; ANILIDE; DNA BINDING PROTEIN; GINSENOSIDE; GLUCOSE; ION CHANNEL; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; PPARGC1A PROTEIN, MOUSE; PRDM16 PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

EID: 84943235808     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.09.064     Document Type: Article
Times cited : (97)

References (34)
  • 1
    • 84913586856 scopus 로고    scopus 로고
    • The browning of white adipose tissue: Some burning issues
    • J. Nedergaard, and B. Cannon The browning of white adipose tissue: some burning issues Cell Metab. 20 2014 396 407
    • (2014) Cell Metab. , vol.20 , pp. 396-407
    • Nedergaard, J.1    Cannon, B.2
  • 2
  • 4
    • 84917690845 scopus 로고    scopus 로고
    • Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: Impact on whole-body energy expenditure
    • M.V. Wu, G. Bikopoulos, S. Hung, and R.B. Ceddia Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure J. Biol. Chem. 289 2014 34129 34140
    • (2014) J. Biol. Chem. , vol.289 , pp. 34129-34140
    • Wu, M.V.1    Bikopoulos, G.2    Hung, S.3    Ceddia, R.B.4
  • 6
    • 84936877196 scopus 로고    scopus 로고
    • Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation
    • A. Jankovic, I. Golic, M. Markelic, A. Stancic, V. Otasevic, B. Buzadzic, A. Korac, and B. Korac Two key temporally distinguishable molecular and cellular components of white adipose tissue browning during cold acclimation J. Physiol. 593 2015 3267 3280
    • (2015) J. Physiol. , vol.593 , pp. 3267-3280
    • Jankovic, A.1    Golic, I.2    Markelic, M.3    Stancic, A.4    Otasevic, V.5    Buzadzic, B.6    Korac, A.7    Korac, B.8
  • 8
    • 84893794489 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors and their ligands: Nutritional and clinical implications-A review
    • B. Grygiel-Gorniak Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications-a review Nutr. J. 13 2014 17
    • (2014) Nutr. J. , vol.13 , pp. 17
    • Grygiel-Gorniak, B.1
  • 9
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • S.E. Nissen, and K. Wolski Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes N. Engl. J. Med. 356 2007 2457 2471
    • (2007) N. Engl. J. Med. , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 10
    • 62649174650 scopus 로고    scopus 로고
    • Risk of acute myocardial infarction in patients treated with thiazolidinediones or other antidiabetic medications
    • K.M. Stockl, L. Le, S. Zhang, and A.S. Harada Risk of acute myocardial infarction in patients treated with thiazolidinediones or other antidiabetic medications Pharmacoepidemiol. Drug Saf. 18 2009 166 174
    • (2009) Pharmacoepidemiol. Drug Saf. , vol.18 , pp. 166-174
    • Stockl, K.M.1    Le, L.2    Zhang, S.3    Harada, A.S.4
  • 11
    • 84943335209 scopus 로고    scopus 로고
    • Berberine induces cell apoptosis through cytochrome C/apoptotic protease-activating factor 1/caspase-3 and apoptosis inducing factor pathway in mouse insulinoma cells
    • X. Fang, X.L. Miao, J.L. Liu, D.W. Zhang, M. Wang, D.D. Zhao, Q.Q. Mu, N. Yu, F.F. Mo, H.P. Yin, and S.H. Gao Berberine induces cell apoptosis through cytochrome C/apoptotic protease-activating factor 1/caspase-3 and apoptosis inducing factor pathway in mouse insulinoma cells Chin. J. Integr. Med. 2015
    • (2015) Chin. J. Integr. Med.
    • Fang, X.1    Miao, X.L.2    Liu, J.L.3    Zhang, D.W.4    Wang, M.5    Zhao, D.D.6    Mu, Q.Q.7    Yu, N.8    Mo, F.F.9    Yin, H.P.10    Gao, S.H.11
  • 15
    • 84891623701 scopus 로고    scopus 로고
    • Ginseng panaxoside Rb1 reduces body weight in diet-induced obese mice
    • N. Lin, D.L. Cai, D. Jin, Y. Chen, and J.J. Shi Ginseng panaxoside Rb1 reduces body weight in diet-induced obese mice Cell Biochem. Biophys. 68 2014 189 194
    • (2014) Cell Biochem. Biophys. , vol.68 , pp. 189-194
    • Lin, N.1    Cai, D.L.2    Jin, D.3    Chen, Y.4    Shi, J.J.5
  • 16
    • 84899803440 scopus 로고    scopus 로고
    • Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet
    • Y. Wu, Y. Yu, A. Szabo, M. Han, and X.F. Huang Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet PLoS One 9 2014 e92618
    • (2014) PLoS One , vol.9 , pp. e92618
    • Wu, Y.1    Yu, Y.2    Szabo, A.3    Han, M.4    Huang, X.F.5
  • 18
    • 84936846304 scopus 로고    scopus 로고
    • Ginsenoside Rb1 ameliorates liver fat accumulation by upregulating perilipin expression in adipose tissue of db/db obese mice
    • X. Yu, L. Ye, H. Zhang, J. Zhao, G. Wang, C. Guo, and W. Shang Ginsenoside Rb1 ameliorates liver fat accumulation by upregulating perilipin expression in adipose tissue of db/db obese mice J. Ginseng Res. 39 2015 199 205
    • (2015) J. Ginseng Res. , vol.39 , pp. 199-205
    • Yu, X.1    Ye, L.2    Zhang, H.3    Zhao, J.4    Wang, G.5    Guo, C.6    Shang, W.7
  • 20
    • 33751079350 scopus 로고    scopus 로고
    • Ginseng: Cardiotonic in adult rat cardiomyocytes, cardiotoxic in neonatal rat cardiomyocytes
    • B.J. Poindexter, A.W. Allison, R.J. Bick, and A. Dasgupta Ginseng: Cardiotonic in adult rat cardiomyocytes, cardiotoxic in neonatal rat cardiomyocytes Life Sci. 79 2006 2337 2344
    • (2006) Life Sci. , vol.79 , pp. 2337-2344
    • Poindexter, B.J.1    Allison, A.W.2    Bick, R.J.3    Dasgupta, A.4
  • 21
    • 77953272248 scopus 로고    scopus 로고
    • Ginsenoside Rb1 protects cardiomyocytes against CoCl2-induced apoptosis in neonatal rats by inhibiting mitochondria permeability transition pore opening
    • H.L. Kong, Z.Q. Li, Y.J. Zhao, S.M. Zhao, L. Zhu, T. Li, Y. Fu, and H.J. Li Ginsenoside Rb1 protects cardiomyocytes against CoCl2-induced apoptosis in neonatal rats by inhibiting mitochondria permeability transition pore opening Acta Pharmacol. Sin. 31 2010 687 695
    • (2010) Acta Pharmacol. Sin. , vol.31 , pp. 687-695
    • Kong, H.L.1    Li, Z.Q.2    Zhao, Y.J.3    Zhao, S.M.4    Zhu, L.5    Li, T.6    Fu, Y.7    Li, H.J.8
  • 22
    • 18244393720 scopus 로고    scopus 로고
    • Developmental toxicity research of ginsenoside Rb1 using a whole mouse embryo culture model, Birth defects research. Part B
    • P. Liu, Y. Xu, H. Yin, J. Wang, K. Chen, and Y. Li Developmental toxicity research of ginsenoside Rb1 using a whole mouse embryo culture model, Birth defects research. Part B Dev. Reprod. Toxicol. 74 2005 207 209
    • (2005) Dev. Reprod. Toxicol. , vol.74 , pp. 207-209
    • Liu, P.1    Xu, Y.2    Yin, H.3    Wang, J.4    Chen, K.5    Li, Y.6
  • 25
    • 84884761856 scopus 로고    scopus 로고
    • Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) in the conversion of white-to-brown adipocytes
    • V. Garcia-Alonso, C. Lopez-Vicario, E. Titos, E. Moran-Salvador, A. Gonzalez-Periz, B. Rius, M. Parrizas, O. Werz, V. Arroyo, and J. Claria Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor gamma (PPARgamma) in the conversion of white-to-brown adipocytes J. Biol. Chem. 288 2013 28230 28242
    • (2013) J. Biol. Chem. , vol.288 , pp. 28230-28242
    • Garcia-Alonso, V.1    Lopez-Vicario, C.2    Titos, E.3    Moran-Salvador, E.4    Gonzalez-Periz, A.5    Rius, B.6    Parrizas, M.7    Werz, O.8    Arroyo, V.9    Claria, J.10
  • 26
    • 53349141483 scopus 로고    scopus 로고
    • Ginsenoside Rb1 stimulates glucose uptake through insulin-like signaling pathway in 3T3-L1 adipocytes
    • W. Shang, Y. Yang, L. Zhou, B. Jiang, H. Jin, and M. Chen Ginsenoside Rb1 stimulates glucose uptake through insulin-like signaling pathway in 3T3-L1 adipocytes J. Endocrinol. 198 2008 561 569
    • (2008) J. Endocrinol. , vol.198 , pp. 561-569
    • Shang, W.1    Yang, Y.2    Zhou, L.3    Jiang, B.4    Jin, H.5    Chen, M.6
  • 30
    • 84872766663 scopus 로고    scopus 로고
    • PPAR-gamma activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic beta-cells
    • H.S. Kim, Y.C. Hwang, S.H. Koo, K.S. Park, M.S. Lee, K.W. Kim, and M.K. Lee PPAR-gamma activation increases insulin secretion through the up-regulation of the free fatty acid receptor GPR40 in pancreatic beta-cells PLoS One 8 2013 e50128
    • (2013) PLoS One , vol.8 , pp. e50128
    • Kim, H.S.1    Hwang, Y.C.2    Koo, S.H.3    Park, K.S.4    Lee, M.S.5    Kim, K.W.6    Lee, M.K.7
  • 31
    • 84862877586 scopus 로고    scopus 로고
    • Early induction of a brown-like phenotype by rosiglitazone in the epicardial adipose tissue of fatty Zucker rats
    • E. Distel, G. Penot, T. Cadoudal, I. Balguy, S. Durant, and C. Benelli Early induction of a brown-like phenotype by rosiglitazone in the epicardial adipose tissue of fatty Zucker rats Biochimie 94 2012 1660 1667
    • (2012) Biochimie , vol.94 , pp. 1660-1667
    • Distel, E.1    Penot, G.2    Cadoudal, T.3    Balguy, I.4    Durant, S.5    Benelli, C.6
  • 33
    • 50049118173 scopus 로고    scopus 로고
    • Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype
    • T. Wenz, F. Diaz, B.M. Spiegelman, and C.T. Moraes Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype Cell Metab. 8 2008 249 256
    • (2008) Cell Metab. , vol.8 , pp. 249-256
    • Wenz, T.1    Diaz, F.2    Spiegelman, B.M.3    Moraes, C.T.4
  • 34
    • 84904647570 scopus 로고    scopus 로고
    • Ginsenoside rb1 protects neonatal rat cardiomyocytes from hypoxia/ischemia induced apoptosis and inhibits activation of the mitochondrial apoptotic pathway
    • X. Yan, J. Tian, H. Wu, Y. Liu, J. Ren, S. Zheng, C. Zhang, C. Yang, Y. Li, and S. Wang Ginsenoside rb1 protects neonatal rat cardiomyocytes from hypoxia/ischemia induced apoptosis and inhibits activation of the mitochondrial apoptotic pathway Evid. Based Complement. Altern. Med. eCAM 2014 2014 149195
    • (2014) Evid. Based Complement. Altern. Med. ECAM , vol.2014 , pp. 149195
    • Yan, X.1    Tian, J.2    Wu, H.3    Liu, Y.4    Ren, J.5    Zheng, S.6    Zhang, C.7    Yang, C.8    Li, Y.9    Wang, S.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.