Wnts grasp the WIF domain of Wnt Inhibitory Factor 1 at two distinct binding sites

FEBS Letters

Volumn 589, Issue 20, 2015, Pages 3044-3051

  Kerekes, Krisztina ^a   Bányai, László ^a   Patthy, László ^a  

^a INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Arginine scanning mutagenesis; Cancer therapy; Homology modeling; Protein protein interaction; Ryk receptor tyrosine kinase; WIF domain; Wnt; Wnt Inhibitory Factor 1

Indexed keywords

SCLEROPROTEIN; UNCLASSIFIED DRUG; WNT INHIBITORY FACTOR 1; WNT5A PROTEIN; WNT7A PROTEIN; ARGININE; ONCOPROTEIN; PROTEIN BINDING; RECOMBINANT PROTEIN; REPRESSOR PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; WIF1 PROTEIN, HUMAN; WNT PROTEIN; WNT5A PROTEIN, HUMAN; WNT7A PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; WIF DOMAIN; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; KINETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN TERTIARY STRUCTURE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ARGININE; BINDING SITES; HUMANS; KINETICS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; REPRESSOR PROTEINS; WNT PROTEINS;

EID: 84943200782     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.08.031     Document Type: Article

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