메뉴 건너뛰기




Volumn 34, Issue 40, 2015, Pages 5152-5162

P73 engages A2B receptor signalling to prime cancer cells to chemotherapy-induced death

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE A2B RECEPTOR; DOXORUBICIN; PROTEIN BCL XL; PROTEIN P53; PROTEIN P73; ANTINEOPLASTIC AGENT; DNA BINDING PROTEIN; NUCLEAR PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; TUMOR SUPPRESSOR PROTEIN P73;

EID: 84943199021     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.436     Document Type: Article
Times cited : (15)

References (49)
  • 1
    • 9944240863 scopus 로고    scopus 로고
    • Splicing DNA-damage responses to tumour cell death
    • Crighton D, Ryan KM. Splicing DNA-damage responses to tumour cell death. Biochim Biophys Acta 2004; 1705: 3-15.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 3-15
    • Crighton, D.1    Ryan, K.M.2
  • 4
    • 53549134949 scopus 로고    scopus 로고
    • TAp73 knockout shows genomic instability with infertility and tumor suppressor functions
    • Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC et al. TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Gene Dev 2008; 22: 2677-2691.
    • (2008) Gene Dev , vol.22 , pp. 2677-2691
    • Tomasini, R.1    Tsuchihara, K.2    Wilhelm, M.3    Fujitani, M.4    Rufini, A.5    Cheung, C.C.6
  • 6
    • 0034079520 scopus 로고    scopus 로고
    • The p53/p63/ p73 family of transcription factors: Overlapping and distinct functions
    • Levrero M, De Laurenzi V, Costanzo A, Gong J, Wang JY, Melino G. The p53/p63/ p73 family of transcription factors: overlapping and distinct functions. J Cell Sci 2000; 113: 1661-1670.
    • (2000) J Cell Sci , vol.113 , pp. 1661-1670
    • Levrero, M.1    De Laurenzi, V.2    Costanzo, A.3    Gong, J.4    Wang, J.Y.5    Melino, G.6
  • 7
    • 0031564954 scopus 로고    scopus 로고
    • P73 is a simian [correction of human] p53-related protein that can induce apoptosis
    • Jost CA, Marin MC, Kaelin WG Jr. p73 is a simian [correction of human] p53-related protein that can induce apoptosis. Nature 1997; 389: 191-194.
    • (1997) Nature , vol.389 , pp. 191-194
    • Jost, C.A.1    Marin, M.C.2    Kaelin Jr, . W.G.3
  • 9
    • 47249130828 scopus 로고    scopus 로고
    • In good times and bad: P73 in cancer
    • Oswald C, Stiewe T. In good times and bad: p73 in cancer. Cell Cycle 2008; 7: 1726-1731.
    • (2008) Cell Cycle , vol.7 , pp. 1726-1731
    • Oswald, C.1    Stiewe, T.2
  • 10
    • 34147190124 scopus 로고    scopus 로고
    • A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo
    • Bell HS, Dufes C, O'Prey J, Crighton D, Bergamaschi D, Lu X et al. A p53-derived apoptotic peptide derepresses p73 to cause tumor regression in vivo. J Clin Invest 2007; 117: 1008-1018.
    • (2007) J Clin Invest , vol.117 , pp. 1008-1018
    • Bell, H.S.1    Dufes, C.2    O'Prey, J.3    Crighton, D.4    Bergamaschi, D.5    Lu, X.6
  • 12
    • 0035209620 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors
    • Fredholm BB, IJzerman AP, Jacobson KA, Klotz KN, Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 2001; 53: 527-552.
    • (2001) Pharmacol Rev , vol.53 , pp. 527-552
    • Fredholm, B.B.1    IJzerman, A.P.2    Jacobson, K.A.3    Klotz, K.N.4    Linden, J.5
  • 13
    • 84887193301 scopus 로고    scopus 로고
    • Extracellular adenosine sensing-A metabolic cell death priming mechanism downstream of p53
    • Long JS, Crighton D, O'Prey J, Mackay G, Zheng L, Palmer TM et al. Extracellular adenosine sensing-A metabolic cell death priming mechanism downstream of p53. Mol Cell 2013; 50: 394-406.
    • (2013) Mol Cell , vol.50 , pp. 394-406
    • Long, J.S.1    Crighton, D.2    O'Prey, J.3    Mackay, G.4    Zheng, L.5    Palmer, T.M.6
  • 14
    • 0030785819 scopus 로고    scopus 로고
    • The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine
    • Blay J, White TD, Hoskin DW. The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine. Cancer Res 1997; 57: 2602-2605.
    • (1997) Cancer Res , vol.57 , pp. 2602-2605
    • Blay, J.1    White, T.D.2    Hoskin, D.W.3
  • 16
  • 17
    • 0034738967 scopus 로고    scopus 로고
    • A ribonucleotide reductase gene is a transcriptional target of p53 and p73
    • Nakano K, Balint E, Ashcroft M, Vousden KH. A ribonucleotide reductase gene is a transcriptional target of p53 and p73. Oncogene 2000; 19: 4283-4289.
    • (2000) Oncogene , vol.19 , pp. 4283-4289
    • Nakano, K.1    Balint, E.2    Ashcroft, M.3    Vousden, K.H.4
  • 18
    • 0030812331 scopus 로고    scopus 로고
    • Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
    • Kaghad M, Bonnet H, Yang A, Creancier L, Biscan JC, Valent A et al. Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers. Cell 1997; 90: 809-819.
    • (1997) Cell , vol.90 , pp. 809-819
    • Kaghad, M.1    Bonnet, H.2    Yang, A.3    Creancier, L.4    Biscan, J.C.5    Valent, A.6
  • 19
    • 1542379662 scopus 로고    scopus 로고
    • P73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation
    • Melino G, Bernassola F, Ranalli M, Yee K, Zong WX, Corazzari M et al. p73 Induces apoptosis via PUMA transactivation and Bax mitochondrial translocation. J Biol Chem 2004; 279: 8076-8083.
    • (2004) J Biol Chem , vol.279 , pp. 8076-8083
    • Melino, G.1    Bernassola, F.2    Ranalli, M.3    Yee, K.4    Zong, W.X.5    Corazzari, M.6
  • 20
    • 77953525327 scopus 로고    scopus 로고
    • Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B
    • Martin AG, Trama J, Crighton D, Ryan KM, Fearnhead HO. Activation of p73 and induction of Noxa by DNA damage requires NF-kappa B. Aging 2009; 1: 335-349.
    • (2009) Aging , vol.1 , pp. 335-349
    • Martin, A.G.1    Trama, J.2    Crighton, D.3    Ryan, K.M.4    Fearnhead, H.O.5
  • 21
    • 0027142106 scopus 로고
    • A single-step staining procedure for the detection and sorting of unfixed apoptotic thymocytes
    • Pellicciari C, Manfredi AA, Bottone MG, Schaack V, Barni S. A single-step staining procedure for the detection and sorting of unfixed apoptotic thymocytes. Eur J Histochem 1993; 37: 381-390.
    • (1993) Eur J Histochem , vol.37 , pp. 381-390
    • Pellicciari, C.1    Manfredi, A.A.2    Bottone, M.G.3    Schaack, V.4    Barni, S.5
  • 22
    • 67649946387 scopus 로고    scopus 로고
    • 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity
    • Borrmann T, Hinz S, Bertarelli DC, Li W, Florin NC, Scheiff AB et al. 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity. J Med Chem 2009; 52: 3994-4006.
    • (2009) J Med Chem , vol.52 , pp. 3994-4006
    • Borrmann, T.1    Hinz, S.2    Bertarelli, D.C.3    Li, W.4    Florin, N.C.5    Scheiff, A.B.6
  • 23
    • 84870850140 scopus 로고    scopus 로고
    • New frontiers in promoting tumour cell death: Targeting apoptosis, necroptosis and autophagy
    • Long JS, Ryan KM. New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy. Oncogene 2012; 31: 5045-5060.
    • (2012) Oncogene , vol.31 , pp. 5045-5060
    • Long, J.S.1    Ryan, K.M.2
  • 26
    • 0030977847 scopus 로고    scopus 로고
    • Target protease specificity of the viral serpin CrmA. Analysis of five caspases
    • Zhou Q, Snipas S, Orth K, Muzio M, Dixit VM, Salvesen GS. Target protease specificity of the viral serpin CrmA. Analysis of five caspases. J Biol Chem 1997; 272: 7797-7800.
    • (1997) J Biol Chem , vol.272 , pp. 7797-7800
    • Zhou, Q.1    Snipas, S.2    Orth, K.3    Muzio, M.4    Dixit, V.M.5    Salvesen, G.S.6
  • 27
    • 43049152912 scopus 로고    scopus 로고
    • TNF-alpha induces two distinct caspase-8 activation pathways
    • Wang L, Du F, Wang X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 2008; 133: 693-703.
    • (2008) Cell , vol.133 , pp. 693-703
    • Wang, L.1    Du, F.2    Wang, X.3
  • 28
    • 41149152733 scopus 로고    scopus 로고
    • How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?
    • Chipuk JE, Green DR. How do BCL-2 proteins induce mitochondrial outer membrane permeabilization? Trends Cell Biol 2008; 18: 157-164.
    • (2008) Trends Cell Biol , vol.18 , pp. 157-164
    • Chipuk, J.E.1    Green, D.R.2
  • 29
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 2010; 11: 621-632.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 30
    • 0033601746 scopus 로고    scopus 로고
    • Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2,-3,-6,-7,-8, and-10 in a caspase-9-dependent manner
    • Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD et al. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2,-3,-6,-7,-8, and-10 in a caspase-9-dependent manner. J Cell Biol 1999; 144: 281-292.
    • (1999) J Cell Biol , vol.144 , pp. 281-292
    • Slee, E.A.1    Harte, M.T.2    Kluck, R.M.3    Wolf, B.B.4    Casiano, C.A.5    Newmeyer, D.D.6
  • 31
    • 0032553485 scopus 로고    scopus 로고
    • Requirement for p53 and p21 to sustain G2 arrest after DNA damage
    • Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282: 1497-1501.
    • (1998) Science , vol.282 , pp. 1497-1501
    • Bunz, F.1    Dutriaux, A.2    Lengauer, C.3    Waldman, T.4    Zhou, S.5    Brown, J.P.6
  • 32
    • 77954338545 scopus 로고    scopus 로고
    • Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons
    • Fricker M, Papadia S, Hardingham GE, Tolkovsky AM. Implication of TAp73 in the p53-independent pathway of Puma induction and Puma-dependent apoptosis in primary cortical neurons. J Neurochem 2010; 114: 772-783.
    • (2010) J Neurochem , vol.114 , pp. 772-783
    • Fricker, M.1    Papadia, S.2    Hardingham, G.E.3    Tolkovsky, A.M.4
  • 33
    • 3142590360 scopus 로고    scopus 로고
    • Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells
    • Lunghi P, Costanzo A, Levrero M, Bonati A. Treatment with arsenic trioxide (ATO) and MEK1 inhibitor activates the p73-p53AIP1 apoptotic pathway in leukemia cells. Blood 2004; 104: 519-525.
    • (2004) Blood , vol.104 , pp. 519-525
    • Lunghi, P.1    Costanzo, A.2    Levrero, M.3    Bonati, A.4
  • 34
    • 57749084642 scopus 로고    scopus 로고
    • PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop
    • Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G et al. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol cell 2008; 32: 803-814.
    • (2008) Mol Cell , vol.32 , pp. 803-814
    • Lapi, E.1    Di Agostino, S.2    Donzelli, S.3    Gal, H.4    Domany, E.5    Rechavi, G.6
  • 35
    • 34248166978 scopus 로고    scopus 로고
    • The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers
    • Leong CO, Vidnovic N, DeYoung MP, Sgroi D, Ellisen LW. The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancers. J Clin Invest 2007; 117: 1370-1380.
    • (2007) J Clin Invest , vol.117 , pp. 1370-1380
    • Leong, C.O.1    Vidnovic, N.2    DeYoung, M.P.3    Sgroi, D.4    Ellisen, L.W.5
  • 36
    • 0033600234 scopus 로고    scopus 로고
    • The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
    • Gong JG, Costanzo A, Yang HQ, Melino G, Kaelin WG Jr, Levrero M et al. The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage. Nature 1999; 399: 806-809.
    • (1999) Nature , vol.399 , pp. 806-809
    • Gong, J.G.1    Costanzo, A.2    Yang, H.Q.3    Melino, G.4    Kaelin Jr, . W.G.5    Levrero, M.6
  • 37
    • 0033600235 scopus 로고    scopus 로고
    • P73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
    • Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399: 814-817.
    • (1999) Nature , vol.399 , pp. 814-817
    • Yuan, Z.M.1    Shioya, H.2    Ishiko, T.3    Sun, X.4    Gu, J.5    Huang, Y.Y.6
  • 38
    • 0033600240 scopus 로고    scopus 로고
    • Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
    • Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature 1999; 399: 809-813.
    • (1999) Nature , vol.399 , pp. 809-813
    • Agami, R.1    Blandino, G.2    Oren, M.3    Shaul, Y.4
  • 39
    • 41849146852 scopus 로고    scopus 로고
    • C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity
    • Sauer M, Bretz AC, Beinoraviciute-Kellner R, Beitzinger M, Burek C, Rosenwald A et al. C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity. Nucleic Acids Res 2008; 36: 1900-1912.
    • (2008) Nucleic Acids Res , vol.36 , pp. 1900-1912
    • Sauer, M.1    Bretz, A.C.2    Beinoraviciute-Kellner, R.3    Beitzinger, M.4    Burek, C.5    Rosenwald, A.6
  • 40
    • 40549120602 scopus 로고    scopus 로고
    • Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin
    • Klanrit P, Flinterman MB, Odell EW, Melino G, Killick R, Norris JS et al. Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or apoptin. Cell Cycle 2008; 7: 205-215.
    • (2008) Cell Cycle , vol.7 , pp. 205-215
    • Klanrit, P.1    Flinterman, M.B.2    Odell, E.W.3    Melino, G.4    Killick, R.5    Norris, J.S.6
  • 41
    • 84875740314 scopus 로고    scopus 로고
    • Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
    • Gao J, Aksoy BA, Dogrusoz U, Dresdner G, Gross B, Sumer SO et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci Signal 2013; 6: pl1.
    • (2013) Sci Signal , vol.6 , pp. l1
    • Gao, J.1    Aksoy, B.A.2    Dogrusoz, U.3    Dresdner, G.4    Gross, B.5    Sumer, S.O.6
  • 42
    • 84866002291 scopus 로고    scopus 로고
    • The cBio cancer genomics portal: An open platform for exploring multidimensional cancer genomics data
    • Cerami E, Gao J, Dogrusoz U, Gross BE, Sumer SO, Aksoy BA et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. Cancer Discov 2012; 2: 401-404.
    • (2012) Cancer Discov , vol.2 , pp. 401-404
    • Cerami, E.1    Gao, J.2    Dogrusoz, U.3    Gross, B.E.4    Sumer, S.O.5    Aksoy, B.A.6
  • 43
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 2011; 39: D945-D950.
    • (2011) Nucleic Acids Res , vol.39 , pp. D945-D950
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3    Cole, C.4    Kok, C.Y.5    Beare, D.6
  • 44
    • 33745885329 scopus 로고    scopus 로고
    • DRAM, a p53-induced modulator of autophagy, is critical for apoptosis
    • Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR et al. DRAM, a p53-induced modulator of autophagy, is critical for apoptosis. Cell 2006; 126: 121-134.
    • (2006) Cell , vol.126 , pp. 121-134
    • Crighton, D.1    Wilkinson, S.2    O'Prey, J.3    Syed, N.4    Smith, P.5    Harrison, P.R.6
  • 45
    • 68049108333 scopus 로고    scopus 로고
    • Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy
    • O'Prey J, Skommer J, Wilkinson S, Ryan KM. Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy. Cell Cycle 2009; 8: 2260-2265.
    • (2009) Cell Cycle , vol.8 , pp. 2260-2265
    • O'Prey, J.1    Skommer, J.2    Wilkinson, S.3    Ryan, K.M.4
  • 46
    • 66149179367 scopus 로고    scopus 로고
    • Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity
    • Wilkinson S, O'Prey J, Fricker M, Ryan KM. Hypoxia-selective macroautophagy and cell survival signaled by autocrine PDGFR activity. Gene Dev 2009; 23: 1283-1288.
    • (2009) Gene Dev , vol.23 , pp. 1283-1288
    • Wilkinson, S.1    O'Prey, J.2    Fricker, M.3    Ryan, K.M.4
  • 48
    • 33847661809 scopus 로고    scopus 로고
    • Protocol for the fast chromatin immunoprecipitation (ChIP) method
    • Nelson JD, Denisenko O, Bomsztyk K. Protocol for the fast chromatin immunoprecipitation (ChIP) method. Nat Protoc 2006; 1: 179-185.
    • (2006) Nat Protoc , vol.1 , pp. 179-185
    • Nelson, J.D.1    Denisenko, O.2    Bomsztyk, K.3
  • 49
    • 0037817848 scopus 로고    scopus 로고
    • A new quantitative assay for cytochrome c release in apoptotic cells
    • Waterhouse NJ, Trapani JA. A new quantitative assay for cytochrome c release in apoptotic cells. Cell Death Differ 2003; 10: 853-855.
    • (2003) Cell Death Differ , vol.10 , pp. 853-855
    • Waterhouse, N.J.1    Trapani, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.