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Volumn 21, Issue 11, 2015, Pages 1385-1395

The burden of multiple sclerosis variants in continental Italians and Sardinians

(39)  Sanna, Serena b   Barizzone, Nadia a   Zara, Ilenia c   Sorosina, Melissa d   Lupoli, Sara f   Porcu, Eleonora b,g   Pitzalis, Maristella b   Zoledziewska, Magdalena b   Esposito, Federica d   Leone, Maurizio a,j   Mulas, Antonella b,g   Cocco, Eleonora i   Ferrigno, Paola e   Guerini, Franca R h   Brambilla, Paola d   Farina, Gabriele g   Murru, Raffaele i   Deidda, Francesca b   Sanna, Sonia b   Loi, Alessia b,g   more..

b CNR   (Italy)

Author keywords

Autoimmune disease; epidemiology; genetic risk score; genetics; human leukocyte antigen; Italy; Mediterranean populations; multiple sclerosis; Sardinia

Indexed keywords

ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE PREDISPOSITION; EUROPE; FEMALE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HETEROZYGOTE; HLA SYSTEM; HUMAN; ITALIAN (CITIZEN); ITALY; MAJOR CLINICAL STUDY; MALE; MULTIPLE SCLEROSIS; POPULATION GENETICS; POPULATION RESEARCH; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; RISK ASSESSMENT; SARDINIA; SARDINIAN; SCORING SYSTEM; SOUTHERN EUROPEAN; ETHNOLOGY; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; RISK; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84943164376     PISSN: 13524585     EISSN: 14770970     Source Type: Journal    
DOI: 10.1177/1352458515596599     Document Type: Article
Times cited : (12)

References (35)
  • 1
    • 84255194782 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci
    • Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist, et al
    • Patsopoulos NA, Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist, et al. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol 2011; 70: 897-912.
    • (2011) Ann Neurol , vol.70 , pp. 897-912
    • Patsopoulos, N.A.1
  • 2
    • 77952884985 scopus 로고    scopus 로고
    • Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis
    • Sanna S, Pitzalis M, Zoledziewska M, et al. Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet 2010; 42: 495-497.
    • (2010) Nat Genet , vol.42 , pp. 495-497
    • Sanna, S.1    Pitzalis, M.2    Zoledziewska, M.3
  • 3
    • 80051684615 scopus 로고    scopus 로고
    • Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
    • International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2
    • International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2, Sawcer S, et al. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature. 2011; 476: 214-219.
    • (2011) Nature , vol.476 , pp. 214-219
    • Sawcer, S.1
  • 4
    • 84887058596 scopus 로고    scopus 로고
    • Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
    • International Multiple Sclerosis Genetics Consortium (IMSGC)
    • International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham AH, Patsopoulos NA, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet 2013; 45: 1353-1360.
    • (2013) Nat Genet , vol.45 , pp. 1353-1360
    • Beecham, A.H.1    Patsopoulos, N.A.2
  • 5
    • 71849098862 scopus 로고    scopus 로고
    • Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score
    • De Jager PL, Chibnik LB, Cui J, et al. Integration of genetic risk factors into a clinical algorithm for multiple sclerosis susceptibility: A weighted genetic risk score. Lancet Neurol 2009; 12: 1111-1119.
    • (2009) Lancet Neurol , vol.12 , pp. 1111-1119
    • De Jager, P.L.1    Chibnik, L.B.2    Cui, J.3
  • 6
    • 79551484517 scopus 로고    scopus 로고
    • Aggregation of multiple sclerosis genetic risk variants in multiple and single case families
    • Gourraud PA, McElroy JP, Caillier SJ, et al. Aggregation of multiple sclerosis genetic risk variants in multiple and single case families. Ann Neurol 2011; 69: 65-74.
    • (2011) Ann Neurol , vol.69 , pp. 65-74
    • Gourraud, P.A.1    McElroy, J.P.2    Caillier, S.J.3
  • 7
    • 84881307811 scopus 로고    scopus 로고
    • Genetic risk variants in African Americans with multiple sclerosis
    • Isobe N, Gourraud PA, Harbo HF, et al. Genetic risk variants in African Americans with multiple sclerosis. Neurology 2013; 81: 219-227.
    • (2013) Neurology , vol.81 , pp. 219-227
    • Isobe, N.1    Gourraud, P.A.2    Harbo, H.F.3
  • 8
    • 84943165393 scopus 로고    scopus 로고
    • An ImmunoChip study of multiple sclerosis risk in African Americans
    • Brain
    • Isobe N, Madireddy L, Khankhanian P, et al. An ImmunoChip study of multiple sclerosis risk in African Americans. Brain Brain 2015; 138: 1518-30.
    • (2015) Brain , vol.138 , pp. 1518-1530
    • Isobe, N.1    Madireddy, L.2    Khankhanian, P.3
  • 9
    • 55549115654 scopus 로고    scopus 로고
    • Genes mirror geography within Europe
    • Novembre J, Johnson T, Bryc K, et al. Genes mirror geography within Europe. Nature 2008; 456: 98-101.
    • (2008) Nature , vol.456 , pp. 98-101
    • Novembre, J.1    Johnson, T.2    Bryc, K.3
  • 10
    • 18244367163 scopus 로고    scopus 로고
    • Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia
    • Marrosu MG, Murru R, Murru MR, et al. Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia. Hum Mol Genet 2001; 10: 1296-2907.
    • (2001) Hum Mol Genet , vol.10 , pp. 1296-2907
    • Marrosu, M.G.1    Murru, R.2    Murru, M.R.3
  • 11
    • 11144358033 scopus 로고    scopus 로고
    • HLA-multiple sclerosis association in continental Italy and correlation with disease prevalence in Europe
    • Ballerini C, Guerini FR, Rombolà G, et al. HLA-multiple sclerosis association in continental Italy and correlation with disease prevalence in Europe. J Neuroimmunol 2004; 150: 178-185.
    • (2004) J Neuroimmunol , vol.150 , pp. 178-185
    • Ballerini, C.1    Guerini, F.R.2    Rombolà, G.3
  • 12
    • 33746588738 scopus 로고    scopus 로고
    • The epidemiology of multiple sclerosis in Europe
    • Pugliatti M, Rosati G, Carton H, et al. The epidemiology of multiple sclerosis in Europe. Eur J Neurol 2006; 13: 700-722.
    • (2006) Eur J Neurol , vol.13 , pp. 700-722
    • Pugliatti, M.1    Rosati, G.2    Carton, H.3
  • 13
    • 29944438955 scopus 로고    scopus 로고
    • Multiple sclerosis in twins from continental Italy and Sardinia: A nationwide study
    • Ristori G, Cannoni S, Stazi MA, et al. Multiple sclerosis in twins from continental Italy and Sardinia: A nationwide study. Ann Neurol 2006; 59: 27-34.
    • (2006) Ann Neurol , vol.59 , pp. 27-34
    • Ristori, G.1    Cannoni, S.2    Stazi, M.A.3
  • 14
    • 84943173068 scopus 로고    scopus 로고
    • Enrichment for Northern European-derived multiple sclerosis risk alleles in Sardinia
    • Hadjixenofontos A, Gourraud PA, Bakthavachalam V, et al. Enrichment for Northern European-derived multiple sclerosis risk alleles in Sardinia. Mult Scler 2015. DOI: 10.1177/1352458515581872.
    • (2015) Mult Scler
    • Hadjixenofontos, A.1    Gourraud, P.A.2    Bakthavachalam, V.3
  • 15
    • 84856261411 scopus 로고    scopus 로고
    • Genome-wide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase
    • Salvi E, Kutalik Z, Glorioso N, et al. Genome-wide association study using a high-density single nucleotide polymorphism array and case-control design identifies a novel essential hypertension susceptibility locus in the promoter region of endothelial NO synthase. Hypertension 2012; 59: 248-255.
    • (2012) Hypertension , vol.59 , pp. 248-255
    • Salvi, E.1    Kutalik, Z.2    Glorioso, N.3
  • 16
    • 79951796542 scopus 로고    scopus 로고
    • Association of the CBLB gene with multiple sclerosis: New evidence from a replication study in an Italian population
    • Corrado L, Bergamaschi L, Barizzone N, et al. Association of the CBLB gene with multiple sclerosis: New evidence from a replication study in an Italian population. J Med Genet 2011; 48: 210-211.
    • (2011) J Med Genet , vol.48 , pp. 210-211
    • Corrado, L.1    Bergamaschi, L.2    Barizzone, N.3
  • 17
    • 0032126141 scopus 로고    scopus 로고
    • HLA associations with multiple sclerosis in the Canary Islands
    • Coraddu F, Reyes-Yanez MP, Parra A, et al. HLA associations with multiple sclerosis in the Canary Islands. J Neuroimmunol 1998; 87: 130-135.
    • (1998) J Neuroimmunol , vol.87 , pp. 130-135
    • Coraddu, F.1    Reyes-Yanez, M.P.2    Parra, A.3
  • 18
    • 0033384955 scopus 로고    scopus 로고
    • Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster
    • Allcock RJ, De la Concha EG, Fernandez-Arquero M, et al. Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster. Hum Immunol 1999; 60: 1266-1273.
    • (1999) Hum Immunol , vol.60 , pp. 1266-1273
    • Allcock, R.J.1    De La Concha, E.G.2    Fernandez-Arquero, M.3
  • 19
    • 0030967709 scopus 로고    scopus 로고
    • HLA-DR and-DQ associations with multiple sclerosis in Turkey
    • Saruhan-Direskeneli G, Esin S, Baykan-Kurt B, et al. HLA-DR and-DQ associations with multiple sclerosis in Turkey. Hum Immunol 1997; 55: 59-65.
    • (1997) Hum Immunol , vol.55 , pp. 59-65
    • Saruhan-Direskeneli, G.1    Esin, S.2    Baykan-Kurt, B.3
  • 20
    • 84900528867 scopus 로고    scopus 로고
    • Genetic risk score of NOS gene variants associated with myocardial infarction correlates with coronary incidence across Europe
    • Carreras-Torres R, Kundu S, Zanetti D, et al. Genetic risk score of NOS gene variants associated with myocardial infarction correlates with coronary incidence across Europe. PLoS One 2014; 9: e96504.
    • (2014) PLoS One , vol.9 , pp. e96504
    • Carreras-Torres, R.1    Kundu, S.2    Zanetti, D.3
  • 21
    • 77953231426 scopus 로고    scopus 로고
    • Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection
    • Zhernakova A, Elbers CC, Ferwerda B, et al. Evolutionary and functional analysis of celiac risk loci reveals SH2B3 as a protective factor against bacterial infection. Am J Hum Genet 2010; 86: 970-977.
    • (2010) Am J Hum Genet , vol.86 , pp. 970-977
    • Zhernakova, A.1    Elbers, C.C.2    Ferwerda, B.3
  • 22
    • 84875952705 scopus 로고    scopus 로고
    • Common risk alleles for inflammatory diseases are targets of recent positive selection
    • Raj T, Kuchroo M, Replogle JM, et al. Common risk alleles for inflammatory diseases are targets of recent positive selection. Am J Hum Genet 2013; 92: 517-529.
    • (2013) Am J Hum Genet , vol.92 , pp. 517-529
    • Raj, T.1    Kuchroo, M.2    Replogle, J.M.3
  • 23
    • 84893660175 scopus 로고    scopus 로고
    • Genes associated with SLE are targets of recent positive selection
    • Ramos PS, Shaftman SR, Ward RC, et al. Genes associated with SLE are targets of recent positive selection. Autoimmune Dis 2014; 2014: 203435.
    • (2014) Autoimmune Dis , vol.2014 , pp. 203435
    • Ramos, P.S.1    Shaftman, S.R.2    Ward, R.C.3
  • 24
    • 84908378499 scopus 로고    scopus 로고
    • The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease
    • Brinkworth JF, Barreiro LB., The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease. Curr Opin Immunol 2014; 31: 66-78.
    • (2014) Curr Opin Immunol , vol.31 , pp. 66-78
    • Brinkworth, J.F.1    Barreiro, L.B.2
  • 25
    • 84918554994 scopus 로고    scopus 로고
    • A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk
    • Yarwood A, Han B, Raychaudhuri S, et al. A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk. Ann Rheum Dis 2015; 74: 170-6.
    • (2015) Ann Rheum Dis , vol.74 , pp. 170-176
    • Yarwood, A.1    Han, B.2    Raychaudhuri, S.3
  • 26
    • 84893804907 scopus 로고    scopus 로고
    • Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants
    • Romanos J, Rosen A, Kumar V, et al. Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants. Gut 2014; 63: 415-422.
    • (2014) Gut , vol.63 , pp. 415-422
    • Romanos, J.1    Rosen, A.2    Kumar, V.3
  • 27
    • 68249108329 scopus 로고    scopus 로고
    • Prediction and interaction in complex disease genetics: Experience in Type 1 diabetes
    • Clayton DG., Prediction and interaction in complex disease genetics: Experience in Type 1 diabetes. PLoS Genet 2009; 5: e1000540.
    • (2009) PLoS Genet , vol.5 , pp. e1000540
    • Clayton, D.G.1
  • 28
    • 82755175640 scopus 로고    scopus 로고
    • Genetic risk prediction in complex disease
    • Jostins L, Barrett JC., Genetic risk prediction in complex disease. Hum Mol Genet 2011; 20: R182-188.
    • (2011) Hum Mol Genet , vol.20 , pp. R182-188
    • Jostins, L.1    Barrett, J.C.2
  • 29
    • 77649289047 scopus 로고    scopus 로고
    • What role for genetics in the prediction of multiple sclerosis?
    • Sawcer S, Ban M, Wason J, et al. What role for genetics in the prediction of multiple sclerosis? Ann Neurol 2010; 67: 3-10.
    • (2010) Ann Neurol , vol.67 , pp. 3-10
    • Sawcer, S.1    Ban, M.2    Wason, J.3
  • 30
    • 77649209124 scopus 로고    scopus 로고
    • The genetic interpretation of area under the ROC curve in genomic profiling
    • Wray NR, Yang J, Goddard ME, et al. The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet 2010; 6: e1000864.
    • (2010) PLoS Genet , vol.6 , pp. e1000864
    • Wray, N.R.1    Yang, J.2    Goddard, M.E.3
  • 31
    • 82455175773 scopus 로고    scopus 로고
    • Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children
    • Kilpeläinen TO, Qi L, Brage S, et al. Physical activity attenuates the influence of FTO variants on obesity risk: A meta-analysis of 218,166 adults and 19,268 children. PLoS Med 2011; 8: e1001116.
    • (2011) PLoS Med , vol.8 , pp. e1001116
    • Kilpeläinen, T.O.1    Qi, L.2    Brage, S.3
  • 32
    • 84901387060 scopus 로고    scopus 로고
    • Gene-lifestyle interaction and Type 2 diabetes: The EPIC interact case-cohort study
    • Langenberg C, Sharp SJ, Franks PW, et al. Gene-lifestyle interaction and Type 2 diabetes: The EPIC interact case-cohort study. PLoS Med 2014; 11: e1001647.
    • (2014) PLoS Med , vol.11 , pp. e1001647
    • Langenberg, C.1    Sharp, S.J.2    Franks, P.W.3
  • 33
    • 84906226879 scopus 로고    scopus 로고
    • Simulation study of gene-by-environment interactions in GWAS implies ample hidden effects
    • Marigorta UM, Gibson GA., Simulation study of gene-by-environment interactions in GWAS implies ample hidden effects. Front Genet 2014; 5: 225.
    • (2014) Front Genet , vol.5 , pp. 225
    • Marigorta, U.M.1    Gibson, G.A.2
  • 34
    • 84901759936 scopus 로고    scopus 로고
    • Studying the elusive environment in large scale
    • Patel CJ, Ioannidis JP., Studying the elusive environment in large scale. JAMA 2014; 311: 2173-2174.
    • (2014) JAMA , vol.311 , pp. 2173-2174
    • Patel, C.J.1    Ioannidis, J.P.2
  • 35
    • 84875963918 scopus 로고    scopus 로고
    • The benefits of using genetic information to design prevention trials
    • Hu Y, Li L, Ehm MG, et al. The benefits of using genetic information to design prevention trials. Am J Hum Genet 2013; 92: 547-557.
    • (2013) Am J Hum Genet , vol.92 , pp. 547-557
    • Hu, Y.1    Li, L.2    Ehm, M.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.