A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects

Frontiers in Genetics

Volumn 5, Issue JUL, 2014, Pages

  Marigorta, Urko M ^a   Gibson, Greg ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Complex disease; Decanalization; Environmental perturbation; Gene by environment; Genetic risk score; GWAS; Modern lifestyle; Obesity

Indexed keywords

ARTICLE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETIC MODEL; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; META ANALYSIS (TOPIC); OBESITY; PHENOTYPE; QUANTITATIVE TRAIT; SCORING SYSTEM; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 84906226879     PISSN: None     EISSN: 16648021     Source Type: Journal    
DOI: 10.3389/fgene.2014.00225     Document Type: Article

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