-
1
-
-
79960505344
-
Risk assessment tools for identifying individuals at risk of developing type 2 diabetes
-
Buijsse, B., Simmons, R.K., Griffin, S.J. and Schulze, M.B. (2011) Risk assessment tools for identifying individuals at risk of developing type 2 diabetes. Epidemiol. Rev., 33, 46-62.
-
(2011)
Epidemiol. Rev.
, vol.33
, pp. 46-62
-
-
Buijsse, B.1
Simmons, R.K.2
Griffin, S.J.3
Schulze, M.B.4
-
2
-
-
67649516627
-
Predicting the 30-year risk of cardiovascular disease: the Framingham heart study
-
Pencina, M.J., D'Agostino, R.B., Larson, M.G., Massaro, J.M. and Vasan, R.S. (2009) Predicting the 30-year risk of cardiovascular disease: the Framingham heart study. Circulation, 119, 3078-3084.
-
(2009)
Circulation
, vol.119
, pp. 3078-3084
-
-
Pencina, M.J.1
D'Agostino, R.B.2
Larson, M.G.3
Massaro, J.M.4
Vasan, R.S.5
-
3
-
-
65649118180
-
ACOG Practice Bulletin No. 103 hereditary breast and ovarian cancer syndrome
-
Lu, K., Kauff, N., Powell, C.B., Chen, L.M., Cass, I., Lancaster, J., Karlan, B., Berchuck, A. and Mutch, D. (2009) ACOG Practice Bulletin No. 103: hereditary breast and ovarian cancer syndrome. Obstet. Gynecol., 113, 957-966.
-
(2009)
Obstet. Gynecol.
, vol.113
, pp. 957-966
-
-
Lu, K.1
Kauff, N.2
Powell, C.B.3
Chen, L.M.4
Cass, I.5
Lancaster, J.6
Karlan, B.7
Berchuck, A.8
Mutch, D.9
-
4
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff, L.A., Sethupathy, P., Junkins, H.A., Ramos, E.M., Mehta, J.P., Collins, F.S. and Manolio, T.A. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc. Natl Acad. Sci. USA, 106, 9362-9367.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 9362-9367
-
-
Hindorff, L.A.1
Sethupathy, P.2
Junkins, H.A.3
Ramos, E.M.4
Mehta, J.P.5
Collins, F.S.6
Manolio, T.A.7
-
5
-
-
57749193136
-
Detecting shared pathogenesis from the shared genetics of immune-related diseases
-
Zhernakova, A., van Diemen, C.C. and Wijmenga, C. (2009) Detecting shared pathogenesis from the shared genetics of immune-related diseases. Nat. Rev. Genet., 10, 43-55.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 43-55
-
-
Zhernakova, A.1
van Diemen, C.C.2
Wijmenga, C.3
-
6
-
-
79851502150
-
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
-
Rossin, E.J., Lage, K., Raychaudhuri, S., Xavier, R.J., Tatar, D., Benita, Y., Cotsapas, C. and Daly, M.J. (2011) Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet., 7, e1001273.
-
(2011)
PLoS Genet
, vol.7
-
-
Rossin, E.J.1
Lage, K.2
Raychaudhuri, S.3
Xavier, R.J.4
Tatar, D.5
Benita, Y.6
Cotsapas, C.7
Daly, M.J.8
-
7
-
-
77949533117
-
A study on the relationships of classifier performance metrics In Tools with Artificial Intelligence, 2009
-
IEEE Computer Society, Washington, DC, USA doi:10.1002/gepi.20600
-
Seliya, N., Khoshgoftaar, T.M. and Van Hulse, J. (2009) A study on the relationships of classifier performance metrics In Tools with Artificial Intelligence, 2009. ICTAI'09. 21st International Conference on, pp. 59-66. IEEE Computer Society, Washington, DC, USA. doi:10.1002/ gepi.20600.
-
(2009)
ICTAI'09. 21st International Conference on
, pp. 59-66
-
-
Seliya, N.1
Khoshgoftaar, T.M.2
Van Hulse, J.3
-
8
-
-
70349280929
-
An experimental comparison of performance measures for classification
-
Ferri, C., Hernández-Orallo, J. and Modroiu, R. (2009) An experimental comparison of performance measures for classification. Pattern Recognit. Lett., 30, 27-38.
-
(2009)
Pattern Recognit. Lett.
, vol.30
, pp. 27-38
-
-
Ferri, C.1
Hernández-Orallo, J.2
Modroiu, R.3
-
9
-
-
33646023117
-
An introduction to ROC analysis
-
Fawcett, T. (2006) An introduction to ROC analysis. Pattern Recognit. Lett., 27, 861-874.
-
(2006)
Pattern Recognit. Lett.
, vol.27
, pp. 861-874
-
-
Fawcett, T.1
-
10
-
-
78751696050
-
Family-based genetic risk prediction of multifactorial disease
-
Ruderfer, D.M., Korn, J. and Purcell, S.M. (2010) Family-based genetic risk prediction of multifactorial disease. Genome Med., 2, 2.
-
(2010)
Genome Med
, vol.2
, pp. 2
-
-
Ruderfer, D.M.1
Korn, J.2
Purcell, S.M.3
-
11
-
-
68249108329
-
Prediction and interaction in complex disease genetics: experience in type 1 diabetes
-
Clayton, D.G. (2009) Prediction and interaction in complex disease genetics: experience in type 1 diabetes. PLoS Genet., 5, e1000540.
-
(2009)
PLoS Genet
, vol.5
-
-
Clayton, D.G.1
-
12
-
-
0032565070
-
Frequency of breast cancer attributable to BRCA1 in a population-based series of American women
-
Newman, B., Mu, H., Butler, L.M., Millikan, R.C., Moorman, P.G. and King, M.C. (1998) Frequency of breast cancer attributable to BRCA1 in a population-based series of American women. JAMA, 279, 915-921.
-
(1998)
JAMA
, vol.279
, pp. 915-921
-
-
Newman, B.1
Mu, H.2
Butler, L.M.3
Millikan, R.C.4
Moorman, P.G.5
King, M.C.6
-
13
-
-
0033740880
-
Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases Anglian Breast Cancer Study Group
-
Anglian Breast Cancer Study Group
-
Anglian Breast Cancer Study Group. (2000) Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Anglian Breast Cancer Study Group. Br. J. Cancer, 83, 1301-1308.
-
(2000)
Br. J. Cancer
, vol.83
, pp. 1301-1308
-
-
-
14
-
-
33845654907
-
Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario Canada
-
Risch, H.A., McLaughlin, J.R., Cole, D.E., Rosen, B., Bradley, L., Fan, I., Tang, J., Li, S., Zhang, S., Shaw, P.A. and Narod, S.A. (2006) Population BRCA1 and BRCA2 mutation frequencies and cancer penetrances: a kin-cohort study in Ontario, Canada. J. Natl Cancer Inst., 98, 1694-1706.
-
(2006)
J. Natl Cancer Inst.
, vol.98
, pp. 1694-1706
-
-
Risch, H.A.1
McLaughlin, J.R.2
Cole, D.E.3
Rosen, B.4
Bradley, L.5
Fan, I.6
Tang, J.7
Li, S.8
Zhang, S.9
Shaw, P.A.10
Narod, S.A.11
-
15
-
-
34248170114
-
Meta-analysis of BRCA1 and BRCA2 penetrance
-
Chen, S. and Parmigiani, G. (2007) Meta-analysis of BRCA1 and BRCA2 penetrance. J. Clin. Oncol., 25, 1329-1333.
-
(2007)
J. Clin. Oncol.
, vol.25
, pp. 1329-1333
-
-
Chen, S.1
Parmigiani, G.2
-
16
-
-
84863035912
-
-
Howlader, N, Noone, A.M, Krapcho, M, Neyman, N, Aminou, R, Waldron, W, Altekruse, SF, Kosary, CL, Ruhl, J and Tatalovich, Z. (2011) SEER cancer statistics review, 1975-2008. http://seer.cancer.gov/csr/1975_2008/.
-
(2011)
SEER cancer statistics review
, pp. 1975-2008
-
-
Howlader, N.1
Noone, A.M.2
Krapcho, M.3
Neyman, N.4
Aminou, R.5
Waldron, W.6
Altekruse, S.F.7
Kosary, C.L.8
Ruhl, J.9
Tatalovich, Z.10
-
17
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for crohn's disease
-
Barrett, J.C., Hansoul, S., Nicolae, D.L., Cho, J.H., Duerr, R.H., Rioux, J.D., Brant, S.R., Silverberg, M.S., Taylor, K.D., Barmada, M.M. et al. (2008) Genome-wide association defines more than 30 distinct susceptibility loci for crohn's disease. Nat. Genet. 40, 955-962.
-
(2008)
Nat. Genet.
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
Brant, S.R.7
Silverberg, M.S.8
Taylor, K.D.9
Barmada, M.M.10
-
18
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke, A., McGovern, D.P., Barrett, J.C., Wang, K., Radford-Smith, G.L., Ahmad, T., Lees, C.W., Balschun, T., Lee, J., Roberts, R. et al. (2010) Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat. Genet., 42, 1118-1125.
-
(2010)
Nat. Genet.
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
Wang, K.4
Radford-Smith, G.L.5
Ahmad, T.6
Lees, C.W.7
Balschun, T.8
Lee, J.9
Roberts, R.10
-
19
-
-
33745966838
-
Narrative review: assessment of C-reactive protein in risk prediction for cardiovascular disease
-
Lloyd-Jones, D.M., Liu, K., Tian, L. and Greenland, P. (2006) Narrative review: assessment of C-reactive protein in risk prediction for cardiovascular disease. Ann. Intern. Med., 145, 35-42.
-
(2006)
Ann. Intern. Med.
, vol.145
, pp. 35-42
-
-
Lloyd-Jones, D.M.1
Liu, K.2
Tian, L.3
Greenland, P.4
-
20
-
-
38549101673
-
The LLP risk model: an individual risk prediction model for lung cancer
-
Cassidy, A., Myles, J.P., van Tongeren, M., Page, R.D., Liloglou, T., Duffy, S.W. and Field, J.K. (2008) The LLP risk model: an individual risk prediction model for lung cancer. Br. J. Cancer, 98, 270-276.
-
(2008)
Br. J. Cancer
, vol.98
, pp. 270-276
-
-
Cassidy, A.1
Myles, J.P.2
van Tongeren, M.3
Page, R.D.4
Liloglou, T.5
Duffy, S.W.6
Field, J.K.7
-
21
-
-
65549129157
-
Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables
-
Seddon, J.M., Reynolds, R., Maller, J., Fagerness, J.A., Daly, M.J. and Rosner, B. (2009) Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables. Invest. Ophthalmol. Vis. Sci., 50, 2044-2053.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 2044-2053
-
-
Seddon, J.M.1
Reynolds, R.2
Maller, J.3
Fagerness, J.A.4
Daly, M.J.5
Rosner, B.6
-
22
-
-
77949578084
-
Performance of common genetic variants in breast-cancer risk models
-
Wacholder, S., Hartge, P., Prentice, R., Garcia-Closas, M., Feigelson, H.S., Diver, W.R., Thun, M.J., Cox, D.G., Hankinson, S.E., Kraft, P. et al. (2010) Performance of common genetic variants in breast-cancer risk models. N. Engl. J. Med., 362, 986-993.
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 986-993
-
-
Wacholder, S.1
Hartge, P.2
Prentice, R.3
Garcia-Closas, M.4
Feigelson, H.S.5
Diver, W.R.6
Thun, M.J.7
Cox, D.G.8
Hankinson, S.E.9
Kraft, P.10
-
23
-
-
77649209124
-
The genetic interpretation of area under the ROC curve in genomic profiling
-
Wray, N.R., Yang, J., Goddard, M.E. and Visscher, P.M. (2010) The genetic interpretation of area under the ROC curve in genomic profiling. PLoS Genet., 6, e1000864.
-
(2010)
PLoS Genet
, vol.6
-
-
Wray, N.R.1
Yang, J.2
Goddard, M.E.3
Visscher, P.M.4
-
24
-
-
79955824808
-
Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening
-
So, H.C., Kwan, J.S., Cherny, S.S. and Sham, P.C. (2011) Risk prediction of complex diseases from family history and known susceptibility loci, with applications for cancer screening. Am. J. Hum. Genet., 88, 548-565.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 548-565
-
-
So, H.C.1
Kwan, J.S.2
Cherny, S.S.3
Sham, P.C.4
-
25
-
-
40949149395
-
Polymorphisms associated with cholesterol and risk of cardiovascular events
-
Kathiresan, S., Melander, O., Anevski, D., Guiducci, C., Burtt, N.P., Roos, C., Hirschhorn, J.N., Berglund, G., Hedblad, B., Groop, L. et al. (2008) Polymorphisms associated with cholesterol and risk of cardiovascular events. N. Engl. J. Med., 358, 1240-1249.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 1240-1249
-
-
Kathiresan, S.1
Melander, O.2
Anevski, D.3
Guiducci, C.4
Burtt, N.P.5
Roos, C.6
Hirschhorn, J.N.7
Berglund, G.8
Hedblad, B.9
Groop, L.10
-
26
-
-
79958230682
-
Genetic variants, cardiovascular risk and genome-wide association studies
-
Companioni, O., Rodríguez Esparragón, F., Fernández-Aceituno, A.M. and Rodríguez Pérez, J.C. (2011) Genetic variants, cardiovascular risk and genome-wide association studies. Rev. Esp. Cardiol., 64, 509-514.
-
(2011)
Rev. Esp. Cardiol.
, vol.64
, pp. 509-514
-
-
Companioni, O.1
Rodríguez Esparragón, F.2
Fernández-Aceituno, A.M.3
Rodríguez Pérez, J.C.4
-
27
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio, T.A., Collins, F.S., Cox, N.J., Goldstein, D.B., Hindorff, L.A., Hunter, D.J., McCarthy, M.I., Ramos, E.M., Cardon, L.R., Chakravarti, A. et al. (2009) Finding the missing heritability of complex diseases. Nature, 461, 747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
-
28
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee, S.H., Wray, N.R., Goddard, M.E. and Visscher, P.M. (2011) Estimating missing heritability for disease from genome-wide association studies. Am. J. Hum. Genet., 88, 294-305.
-
(2011)
Am. J. Hum. Genet.
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
Visscher, P.M.4
-
29
-
-
68449086236
-
Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
-
Purcell, S.M., Wray, N.R., Stone, J.L., Visscher, P.M., O'Donovan, M.C., Sullivan, P.F. and Sklar, P. (2009) Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature, 460, 748-752.
-
(2009)
Nature
, vol.460
, pp. 748-752
-
-
Purcell, S.M.1
Wray, N.R.2
Stone, J.L.3
Visscher, P.M.4
O'Donovan, M.C.5
Sullivan, P.F.6
Sklar, P.7
-
30
-
-
79957471451
-
Improved risk prediction for Crohn's disease with a multi-locus approach
-
Kang, J., Kugathasan, S., Georges, M., Zhao, H. and Cho, J.H. (2011) Improved risk prediction for Crohn's disease with a multi-locus approach. Hum. Mol. Genet., 20, 2435-2442.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2435-2442
-
-
Kang, J.1
Kugathasan, S.2
Georges, M.3
Zhao, H.4
Cho, J.H.5
-
31
-
-
73449129712
-
From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes
-
Wei, Z., Wang, K., Qu, H.Q., Zhang, H., Bradfield, J., Kim, C., Frackleton, E., Hou, C., Glessner, J.T., Chiavacci, R. et al. (2009) From disease association to risk assessment: an optimistic view from genome-wide association studies on type 1 diabetes. PLoS Genet., 5, e1000678.
-
(2009)
PLoS Genet
, vol.5
-
-
Wei, Z.1
Wang, K.2
Qu, H.Q.3
Zhang, H.4
Bradfield, J.5
Kim, C.6
Frackleton, E.7
Hou, C.8
Glessner, J.T.9
Chiavacci, R.10
-
32
-
-
80051817547
-
Evaluation of polygenic risk scores for predicting breast and prostate cancer risk
-
Machiela, M.J., Chen, C.Y., Chen, C., Chanock, S.J., Hunter, D.J. and Kraft, P. (2011) Evaluation of polygenic risk scores for predicting breast and prostate cancer risk. Genet. Epidemiol., 35, 506-514.
-
(2011)
Genet. Epidemiol.
, vol.35
, pp. 506-514
-
-
Machiela, M.J.1
Chen, C.Y.2
Chen, C.3
Chanock, S.J.4
Hunter, D.J.5
Kraft, P.6
-
33
-
-
78650134241
-
Multi-locus models of genetic risk of disease
-
Wray, N.R. and Goddard, M.E. (2010) Multi-locus models of genetic risk of disease. Genome Med., 2, 10.
-
(2010)
Genome Med
, vol.2
, pp. 10
-
-
Wray, N.R.1
Goddard, M.E.2
-
34
-
-
72649086454
-
Successful implementation of a national HLA-B*5701 genetic testing service in Canada
-
Lalonde, R.G., Thomas, R., Rachlis, A., Gill, M.J., Roger, M., Angel, J.B., Smith, G., Higgins, N. and Trottier, B. (2010) Successful implementation of a national HLA-B*5701 genetic testing service in Canada. Tissue Antigens, 75, 12-18.
-
(2010)
Tissue Antigens
, vol.75
, pp. 12-18
-
-
Lalonde, R.G.1
Thomas, R.2
Rachlis, A.3
Gill, M.J.4
Roger, M.5
Angel, J.B.6
Smith, G.7
Higgins, N.8
Trottier, B.9
-
35
-
-
55649105963
-
Clinical risk factors, DNA variants, and the development of type 2 diabetes
-
Lyssenko, V., Jonsson, A., Almgren, P., Pulizzi, N., Isomaa, B., Tuomi, T., Berglund, G., Altshuler, D., Nilsson, P. and Groop, L. (2008) Clinical risk factors, DNA variants, and the development of type 2 diabetes. N. Engl. J. Med., 359, 2220-2232.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 2220-2232
-
-
Lyssenko, V.1
Jonsson, A.2
Almgren, P.3
Pulizzi, N.4
Isomaa, B.5
Tuomi, T.6
Berglund, G.7
Altshuler, D.8
Nilsson, P.9
Groop, L.10
-
37
-
-
79251645624
-
Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease
-
Worthey, E.A., Mayer, A.N., Syverson, G.D., Helbling, D., Bonacci, B.B., Decker, B., Serpe, J.M., Dasu, T., Tschannen, M.R., Veith, R.L. et al. (2011) Making a definitive diagnosis: successful clinical application of whole exome sequencing in a child with intractable inflammatory bowel disease. Genet. Med., 13, 255-262.
-
(2011)
Genet. Med.
, vol.13
, pp. 255-262
-
-
Worthey, E.A.1
Mayer, A.N.2
Syverson, G.D.3
Helbling, D.4
Bonacci, B.B.5
Decker, B.6
Serpe, J.M.7
Dasu, T.8
Tschannen, M.R.9
Veith, R.L.10
-
38
-
-
77958469483
-
Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia
-
Rios, J., Stein, E., Shendure, J., Hobbs, H.H. and Cohen, J.C. (2010) Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia. Hum. Mol. Genet., 19, 4313-4318.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 4313-4318
-
-
Rios, J.1
Stein, E.2
Shendure, J.3
Hobbs, H.H.4
Cohen, J.C.5
-
39
-
-
79955016374
-
Identification of a novel tp53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML
-
Link, D.C., Schuettpelz, L.G., Shen, D., Wang, J., Walter, M.J., Kulkarni, S., Payton, J.E., Ivanovich, J., Goodfellow, P.J., Le Beau, M. et al. (2011) Identification of a novel tp53 cancer susceptibility mutation through whole-genome sequencing of a patient with therapy-related AML. JAMA, 305, 1568-1576.
-
(2011)
JAMA
, vol.305
, pp. 1568-1576
-
-
Link, D.C.1
Schuettpelz, L.G.2
Shen, D.3
Wang, J.4
Walter, M.J.5
Kulkarni, S.6
Payton, J.E.7
Ivanovich, J.8
Goodfellow, P.J.9
Le Beau, M.10
-
40
-
-
78651393550
-
Carrier testing for severe childhood recessive diseases by next-generation sequencing
-
Bell, C.J., Dinwiddie, D.L., Miller, N.A., Hateley, S.L., Ganusova, E.E., Mudge, J., Langley, R.J., Zhang, L., Lee, C.C., Schilkey, F.D. et al. (2011) Carrier testing for severe childhood recessive diseases by next-generation sequencing. Sci. Transl. Med., 3, 65ra4.
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Bell, C.J.1
Dinwiddie, D.L.2
Miller, N.A.3
Hateley, S.L.4
Ganusova, E.E.5
Mudge, J.6
Langley, R.J.7
Zhang, L.8
Lee, C.C.9
Schilkey, F.D.10
-
41
-
-
79953808430
-
Role of molecular genetics in transforming diagnosis of diabetes mellitus
-
Molven, A. and Njølstad, P.R. (2011) Role of molecular genetics in transforming diagnosis of diabetes mellitus. Expert Rev. Mol. Diagn., 11, 313-320.
-
(2011)
Expert Rev. Mol. Diagn.
, vol.11
, pp. 313-320
-
-
Molven, A.1
Njølstad, P.R.2
-
42
-
-
67650925282
-
Disclosure of APOE genotype for risk of Alzheimer's disease
-
Green, R.C., Roberts, J.S., Cupples, L.A., Relkin, N.R., Whitehouse, P.J., Brown, T., Eckert, S.L., Butson, M., Sadovnick, A.D., Quaid, K.A. et al. (2009) Disclosure of APOE genotype for risk of Alzheimer's disease. N. Engl. J. Med., 361, 245-254.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 245-254
-
-
Green, R.C.1
Roberts, J.S.2
Cupples, L.A.3
Relkin, N.R.4
Whitehouse, P.J.5
Brown, T.6
Eckert, S.L.7
Butson, M.8
Sadovnick, A.D.9
Quaid, K.A.10
-
43
-
-
55049135914
-
Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours
-
Marteau, T.M., French, D.P., Griffin, S.J., Prevost, A.T., Sutton, S., Watkinson, C., Attwood, S. and ollands, G.J. (2010) Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours. Cochrane Database Syst. Rev., 10, CD007275.
-
(2010)
Cochrane Database Syst. Rev.
, vol.10
-
-
Marteau, T.M.1
French, D.P.2
Griffin, S.J.3
Prevost, A.T.4
Sutton, S.5
Watkinson, C.6
Attwood, S.7
ollands, G.J.8
-
44
-
-
79851493086
-
Effect of direct-to-consumer genomewide profiling to assess disease risk
-
Bloss, C.S., Schork, N.J. and Topol, E.J. (2011) Effect of direct-to-consumer genomewide profiling to assess disease risk. N. Engl. J. Med., 364, 524-534.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 524-534
-
-
Bloss, C.S.1
Schork, N.J.2
Topol, E.J.3
-
45
-
-
79959851714
-
International Parkinson's Disease Genomics Consortium and Wellcome Trust Case Control Consortium 2. A two-stage meta-analysis identifies several new Loci for Parkinson's disease
-
International Parkinson's Disease Genomics Consortium and Wellcome Trust Case Control Consortium 2. (2011) A two-stage meta-analysis identifies several new Loci for Parkinson's disease. PLoS Genet., 7, e1002142.
-
(2011)
PLoS Genet
, vol.7
-
-
-
46
-
-
79951811351
-
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
-
Nalls, M.A., Plagnol, V., Hernandez, D.G., Sharma, M., Sheerin, U.M., Saad, M., Simon-Sanchez, J., Schulte, C., Lesage, S., Sveinbjornsdottir, S. et al. (2011) Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies. Lancet, 377, 641-649.
-
(2011)
Lancet
, vol.377
, pp. 641-649
-
-
Nalls, M.A.1
Plagnol, V.2
Hernandez, D.G.3
Sharma, M.4
Sheerin, U.M.5
Saad, M.6
Simon-Sanchez, J.7
Schulte, C.8
Lesage, S.9
Sveinbjornsdottir, S.10
-
47
-
-
77952147434
-
Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration
-
Chen, W., Stambolian, D., Edwards, A.O., Branham, K.E., Othman, M., Jakobsdottir, J., Tosakulwong, N., Pericak-Vance, M.A., Campochiaro, P.A., Klein, M.L. et al. (2010) Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration. Proc. Natl Acad. Sci. USA, 107, 7401-7406.
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 7401-7406
-
-
Chen, W.1
Stambolian, D.2
Edwards, A.O.3
Branham, K.E.4
Othman, M.5
Jakobsdottir, J.6
Tosakulwong, N.7
Pericak-Vance, M.A.8
Campochiaro, P.A.9
Klein, M.L.10
-
48
-
-
77954143522
-
Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
-
Voight, B.F., Scott, L.J., Steinthorsdottir, V., Morris, A.P., Dina, C., Welch, R.P., Zeggini, E., Huth, C., Aulchenko, Y.S., Thorleifsson, G. et al. (2010) Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis. Nat. Genet., 42, 579-589.
-
(2010)
Nat. Genet.
, vol.42
, pp. 579-589
-
-
Voight, B.F.1
Scott, L.J.2
Steinthorsdottir, V.3
Morris, A.P.4
Dina, C.5
Welch, R.P.6
Zeggini, E.7
Huth, C.8
Aulchenko, Y.S.9
Thorleifsson, G.10
-
49
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson, C.A., Boucher, G., Lees, C.W., Franke, A., D'Amato, M., Taylor, K.D., Lee, J.C., Goyette, P., Imielinski, M., Latiano, A. et al. (2011) Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat. Genet., 43, 246-252.
-
(2011)
Nat. Genet.
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
Franke, A.4
D'Amato, M.5
Taylor, K.D.6
Lee, J.C.7
Goyette, P.8
Imielinski, M.9
Latiano, A.10
-
50
-
-
70449719129
-
Genotyping for NOD2 genetic variants and Crohn disease: a metaanalysis
-
Yazdanyar, S., Weischer, M. and Nordestgaard, B.G. (2009) Genotyping for NOD2 genetic variants and Crohn disease: a metaanalysis. Clin. Chem., 55, 1950-1957.
-
(2009)
Clin. Chem.
, vol.55
, pp. 1950-1957
-
-
Yazdanyar, S.1
Weischer, M.2
Nordestgaard, B.G.3
-
51
-
-
77952888454
-
Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
-
Stahl, E.A., Raychaudhuri, S., Remmers, E.F., Xie, G., Eyre, S., Thomson, B.P., Li, Y., Kurreeman, F.A., Zhernakova, A., Hinks, A. et al. (2010) Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. Nat. Genet., 42, 508-514.
-
(2010)
Nat. Genet.
, vol.42
, pp. 508-514
-
-
Stahl, E.A.1
Raychaudhuri, S.2
Remmers, E.F.3
Xie, G.4
Eyre, S.5
Thomson, B.P.6
Li, Y.7
Kurreeman, F.A.8
Zhernakova, A.9
Hinks, A.10
-
52
-
-
79953204259
-
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
-
Schunkert, H., Konig, I.R., Kathiresan, S., Reilly, M.P., Assimes, T.L., Holm, H., Preuss, M., Stewart, A.F., Barbalic, M., Gieger, C. et al. (2011) Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat. Genet., 43, 333-338.
-
(2011)
Nat. Genet.
, vol.43
, pp. 333-338
-
-
Schunkert, H.1
Konig, I.R.2
Kathiresan, S.3
Reilly, M.P.4
Assimes, T.L.5
Holm, H.6
Preuss, M.7
Stewart, A.F.8
Barbalic, M.9
Gieger, C.10
-
53
-
-
77952887426
-
Genome-wide association study identifies five new breast cancer susceptibility loci
-
Turnbull, C., Ahmed, S., Morrison, J., Pernet, D., Renwick, A., Maranian, M., Seal, S., Ghoussaini, M., Hines, S., Healey, C.S. et al. (2010) Genome-wide association study identifies five new breast cancer susceptibility loci. Nat. Genet., 42, 504-517.
-
(2010)
Nat. Genet.
, vol.42
, pp. 504-517
-
-
Turnbull, C.1
Ahmed, S.2
Morrison, J.3
Pernet, D.4
Renwick, A.5
Maranian, M.6
Seal, S.7
Ghoussaini, M.8
Hines, S.9
Healey, C.S.10
-
54
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with alzheimer's disease
-
Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M.L., Pahwa, J.S., Moskvina, V., Dowzell, K., Williams, A. et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with alzheimer's disease. Nat. Genet., 41, 1088-1093.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
Sims, R.4
Gerrish, A.5
Hamshere, M.L.6
Pahwa, J.S.7
Moskvina, V.8
Dowzell, K.9
Williams, A.10
-
55
-
-
77955036445
-
Association of CR1 CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals
-
Corneveaux, J.J., Myers, A.J., Allen, A.N., Pruzin, J.J., Ramirez, M., Engel, A., Nalls, M.A., Chen, K., Lee, W., Chewning, K. et al. (2010) Association of CR1, CLU and PICALM with Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. Hum. Mol. Genet., 19, 3295-3301.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 3295-3301
-
-
Corneveaux, J.J.1
Myers, A.J.2
Allen, A.N.3
Pruzin, J.J.4
Ramirez, M.5
Engel, A.6
Nalls, M.A.7
Chen, K.8
Lee, W.9
Chewning, K.10
-
56
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6 IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
De Jager, P.L., Jia, X., Wang, J., de Bakker, P.I., Ottoboni, L., Aggarwal, N.T., Piccio, L., Raychaudhuri, S., Tran, D., Aubin, C. et al. (2009) Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat. Genet., 41, 776-782.
-
(2009)
Nat. Genet.
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
de Bakker, P.I.4
Ottoboni, L.5
Aggarwal, N.T.6
Piccio, L.7
Raychaudhuri, S.8
Tran, D.9
Aubin, C.10
-
57
-
-
79151475816
-
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies
-
Shyn, S.I., Shi, J., Kraft, J.B., Potash, J.B., Knowles, J.A., Weissman, M.M., Garriock, H.A., Yokoyama, J.S., McGrath, P.J., Peters, E.J. et al. (2009) Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies. Mol. Psychiatr., 16, 202-215.
-
(2009)
Mol. Psychiatr.
, vol.16
, pp. 202-215
-
-
Shyn, S.I.1
Shi, J.2
Kraft, J.B.3
Potash, J.B.4
Knowles, J.A.5
Weissman, M.M.6
Garriock, H.A.7
Yokoyama, J.S.8
McGrath, P.J.9
Peters, E.J.10
-
58
-
-
66149092770
-
Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry
-
Scott, L.J., Muglia, P., Kong, X.Q., Guan, W., Flickinger, M., Upmanyu, R., Tozzi, F., Li, J.Z., Burmeister, M., Absher, D. et al. (2009) Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry. Proc. Natl Acad. Sci. USA, 106, 7501-7506.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 7501-7506
-
-
Scott, L.J.1
Muglia, P.2
Kong, X.Q.3
Guan, W.4
Flickinger, M.5
Upmanyu, R.6
Tozzi, F.7
Li, J.Z.8
Burmeister, M.9
Absher, D.10
-
59
-
-
38649125210
-
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK KIAA1542 and other loci
-
Harley, J.B., Alarcon-Riquelme, M.E., Criswell, L.A., Jacob, C.O., Kimberly, R.P., Moser, K.L., Tsao, B.P., Vyse, T.J., Langefeld, C.D., Nath, S.K. et al. (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. Nat. Genet., 40, 204-210.
-
(2008)
Nat. Genet.
, vol.40
, pp. 204-210
-
-
Harley, J.B.1
Alarcon-Riquelme, M.E.2
Criswell, L.A.3
Jacob, C.O.4
Kimberly, R.P.5
Moser, K.L.6
Tsao, B.P.7
Vyse, T.J.8
Langefeld, C.D.9
Nath, S.K.10
-
60
-
-
56749176944
-
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer
-
Houlston, R.S., Webb, E., Broderick, P., Pittman, A.M., Di Bernardo, M.C., Lubbe, S., Chandler, I., Vijayakrishnan, J., Sullivan, K., Penegar, S. et al. (2008) Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. Nat. Genet., 40, 1426-1435.
-
(2008)
Nat. Genet.
, vol.40
, pp. 1426-1435
-
-
Houlston, R.S.1
Webb, E.2
Broderick, P.3
Pittman, A.M.4
Di Bernardo, M.C.5
Lubbe, S.6
Chandler, I.7
Vijayakrishnan, J.8
Sullivan, K.9
Penegar, S.10
-
61
-
-
70349545839
-
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study
-
Eeles, R.A., Kote-Jarai, Z., Al Olama, A.A., Giles, G.G., Guy, M., Severi, G., Muir, K., Hopper, J.L., Henderson, B.E., Haiman, C.A. et al. (2009) Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat. Genet., 41, 1116-1121.
-
(2009)
Nat. Genet.
, vol.41
, pp. 1116-1121
-
-
Eeles, R.A.1
Kote-Jarai, Z.2
Al Olama, A.A.3
Giles, G.G.4
Guy, M.5
Severi, G.6
Muir, K.7
Hopper, J.L.8
Henderson, B.E.9
Haiman, C.A.10
-
62
-
-
77957571905
-
A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
-
Goode, E.L., Chenevix-Trench, G., Song, H., Ramus, S.J., Notaridou, M., Lawrenson, K., Widschwendter, M., Vierkant, R.A., Larson, M.C., Kjaer, S.K. et al. (2010) A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat. Genet., 42, 874-879.
-
(2010)
Nat. Genet.
, vol.42
, pp. 874-879
-
-
Goode, E.L.1
Chenevix-Trench, G.2
Song, H.3
Ramus, S.J.4
Notaridou, M.5
Lawrenson, K.6
Widschwendter, M.7
Vierkant, R.A.8
Larson, M.C.9
Kjaer, S.K.10
-
63
-
-
69349102630
-
A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22 2
-
Song, H., Ramus, S.J., Tyrer, J., Bolton, K.L., Gentry-Maharaj, A., Wozniak, E., Anton-Culver, H., Chang-Claude, J., Cramer, D.W., DiCioccio, R. et al. (2009) A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat. Genet., 41, 996-1000.
-
(2009)
Nat. Genet.
, vol.41
, pp. 996-1000
-
-
Song, H.1
Ramus, S.J.2
Tyrer, J.3
Bolton, K.L.4
Gentry-Maharaj, A.5
Wozniak, E.6
Anton-Culver, H.7
Chang-Claude, J.8
Cramer, D.W.9
DiCioccio, R.10
|