Rapidly Escalating Hepcidin and Associated Serum Iron Starvation Are Features of the Acute Response to Typhoid Infection in Humans

PLoS Neglected Tropical Diseases

Volumn 9, Issue 9, 2015, Pages

  Darton, Thomas C ^a,b   Blohmke, Christoph J ^a,b   Giannoulatou, Eleni ^c   Waddington, Claire S ^a,b   Jones, Claire ^a,b   Sturges, Pamela ^d   Webster, Craig ^d   Drakesmith, Hal ^b,e   Pollard, Andrew J ^a,b   Armitage, Andrew E ^e  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NIHR OXFORD BIOMEDICAL RESEARCH CENTRE   (United Kingdom)

^c VICTOR CHANG CARDIAC RESEARCH INSTITUTE   (Australia)

^d BIRMINGHAM HEARTLANDS HOSPITAL   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; FERRITIN; HEMOGLOBIN; HEPCIDIN; INTERLEUKIN 6; IRON; TRANSFERRIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ACUTE PHASE RESPONSE; ADULT; ARTICLE; CLINICAL FEATURE; CYTOKINE RESPONSE; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; FEMALE; HUMAN; MALE; MEAN CORPUSCULAR VOLUME; NORMAL HUMAN; STARVATION; TYPHOID FEVER; UPREGULATION; ADOLESCENT; BLOOD; CHEMISTRY; FEVER; IMMUNOLOGY; INNATE IMMUNITY; MIDDLE AGED; PATHOLOGY; SERUM; YOUNG ADULT;

ADOLESCENT; ADULT; C-REACTIVE PROTEIN; CYTOKINES; FEMALE; FERRITINS; FEVER; HEALTHY VOLUNTEERS; HEPCIDINS; HUMANS; IMMUNITY, INNATE; IRON; MALE; MIDDLE AGED; SERUM; TYPHOID FEVER; YOUNG ADULT;

EID: 84943144463     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0004029     Document Type: Article

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