-
1
-
-
84865968858
-
Endothelium-neutrophil interactions in ANCA-associated diseases
-
Halbwachs L, Lesavre P. Endothelium-neutrophil interactions in ANCA-associated diseases. J Am Soc Nephrol 2012; 23: 1449-1461.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 1449-1461
-
-
Halbwachs, L.1
Lesavre, P.2
-
2
-
-
84875603640
-
Pathogenesis of antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis
-
Jennette JC, Falk RJ, Hu P et al. Pathogenesis of antineutrophil cytoplasmic autoantibody-associated small-vessel vasculitis. Annu Rev Pathol 2013; 8: 139-160.
-
(2013)
Annu Rev Pathol
, vol.8
, pp. 139-160
-
-
Jennette, J.C.1
Falk, R.J.2
Hu, P.3
-
3
-
-
79952184992
-
New pathophysiological insights and treatment of ANCA-associated vasculitis
-
Wilde B, van Paassen P, Witzke O et al. New pathophysiological insights and treatment of ANCA-associated vasculitis. Kidney Int 2011; 79: 599-612.
-
(2011)
Kidney Int
, vol.79
, pp. 599-612
-
-
Wilde, B.1
Van Paassen, P.2
Witzke, O.3
-
4
-
-
84888376081
-
Pathogenesis of ANCA-associated vasculitis: New possibilities for intervention
-
Kallenberg CG, Stegeman CA, Abdulahad WH et al. Pathogenesis of ANCA-associated vasculitis: new possibilities for intervention. Am J Kidney Dis 2013; 62: 1176-1187.
-
(2013)
Am J Kidney Dis
, vol.62
, pp. 1176-1187
-
-
Kallenberg, C.G.1
Stegeman, C.A.2
Abdulahad, W.H.3
-
5
-
-
21244503148
-
The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies
-
Xiao H, Heeringa P, Liu Z et al. The role of neutrophils in the induction of glomerulonephritis by anti-myeloperoxidase antibodies. Am J Pathol 2005; 167: 39-45.
-
(2005)
Am J Pathol
, vol.167
, pp. 39-45
-
-
Xiao, H.1
Heeringa, P.2
Liu, Z.3
-
6
-
-
84864748957
-
How anti-neutrophil cytoplasmic autoantibodies activate neutrophils
-
Kettritz R. How anti-neutrophil cytoplasmic autoantibodies activate neutrophils. Clin Exp Immunol 2012; 169: 220-228.
-
(2012)
Clin Exp Immunol
, vol.169
, pp. 220-228
-
-
Kettritz, R.1
-
7
-
-
33745559712
-
Neutrophil serine proteases: Specific regulators of inflammation
-
Pham CT. Neutrophil serine proteases: specific regulators of inflammation. Nat Rev Immunol 2006; 6: 541-550.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 541-550
-
-
Pham, C.T.1
-
8
-
-
84859950056
-
NSP4, an elastase-related protease in human neutrophils with arginine specificity
-
USA
-
Perera NC, Schilling O, Kittel H et al. NSP4, an elastase-related protease in human neutrophils with arginine specificity. Proc Natl Acad Sci USA 2012; 109: 6229-6234.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 6229-6234
-
-
Perera, N.C.1
Schilling, O.2
Kittel, H.3
-
9
-
-
78650096176
-
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases
-
Korkmaz B, Horwitz MS, Jenne DE et al. Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev 2010; 62: 726-759.
-
(2010)
Pharmacol Rev
, vol.62
, pp. 726-759
-
-
Korkmaz, B.1
Horwitz, M.S.2
Jenne, D.E.3
-
10
-
-
84863269507
-
Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis
-
Schreiber A, Pham CT, Hu Y et al. Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis. J Am Soc Nephrol 2012; 23: 470-482.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 470-482
-
-
Schreiber, A.1
Pham, C.T.2
Hu, Y.3
-
11
-
-
0346732028
-
Proteinase 3 sidesteps caspases and cleaves p21(Waf1/Cip1/Sdi1) to induce endothelial cell apoptosis
-
Pendergraft WF 3rd, Rudolph EH, Falk RJ et al. Proteinase 3 sidesteps caspases and cleaves p21(Waf1/Cip1/Sdi1) to induce endothelial cell apoptosis. Kidney Int 2004; 65: 75-84.
-
(2004)
Kidney Int
, vol.65
, pp. 75-84
-
-
Pendergraft, W.F.1
Rudolph, E.H.2
Falk, R.J.3
-
12
-
-
0036892507
-
Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways
-
Preston GA, Zarella CS, Pendergraft WF 3rd et al. Novel effects of neutrophil-derived proteinase 3 and elastase on the vascular endothelium involve in vivo cleavage of NF-kappaB and proapoptotic changes in JNK, ERK, and p38 MAPK signaling pathways. J Am Soc Nephrol 2002; 13: 2840-2849.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2840-2849
-
-
Preston, G.A.1
Zarella, C.S.2
Pendergraft, W.F.3
-
13
-
-
77749320923
-
Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products
-
Kleifeld O, Doucet A, auf dem Keller U et al. Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products. Nat Biotechnol 2010; 28: 281-288.
-
(2010)
Nat Biotechnol
, vol.28
, pp. 281-288
-
-
Kleifeld, O.1
Doucet, A.2
Auf Dem Keller, U.3
-
14
-
-
0037032544
-
Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation
-
Witko-Sarsat V, Canteloup S, Durant S et al. Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation. J Biol Chem 2002; 277: 47338-47347.
-
(2002)
J Biol Chem
, vol.277
, pp. 47338-47347
-
-
Witko-Sarsat, V.1
Canteloup, S.2
Durant, S.3
-
15
-
-
84907494620
-
Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation
-
Loison F, Zhu H, Karatepe K et al. Proteinase 3-dependent caspase-3 cleavage modulates neutrophil death and inflammation. J Clin Invest 2014; 124: 4445-4458.
-
(2014)
J Clin Invest
, vol.124
, pp. 4445-4458
-
-
Loison, F.1
Zhu, H.2
Karatepe, K.3
-
16
-
-
0014518082
-
The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin
-
Turini P, Kurooka S, Steer M et al. The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin. J Pharmacol Exp Ther 1969; 167: 98-104.
-
(1969)
J Pharmacol Exp Ther
, vol.167
, pp. 98-104
-
-
Turini, P.1
Kurooka, S.2
Steer, M.3
-
17
-
-
0029242261
-
Identification of CG-1, a natural peptide antibiotic derived from human neutrophil cathepsin G
-
Miyasaki KT, Qu XD, Harwig SS et al. Identification of CG-1, a natural peptide antibiotic derived from human neutrophil cathepsin G. Adv Dental Res 1995; 9: 63-66.
-
(1995)
Adv Dental Res
, vol.9
, pp. 63-66
-
-
Miyasaki, K.T.1
Qu, X.D.2
Harwig, S.S.3
-
18
-
-
0032038653
-
Elastase is the only human neutrophil granule protein that alone is responsible for in vitro killing of Borrelia burgdorferi
-
Garcia R, Gusmani L, Murgia R et al. Elastase is the only human neutrophil granule protein that alone is responsible for in vitro killing of Borrelia burgdorferi. Infect Immun 1998; 66: 1408-1412.
-
(1998)
Infect Immun
, vol.66
, pp. 1408-1412
-
-
Garcia, R.1
Gusmani, L.2
Murgia, R.3
-
19
-
-
0033056463
-
The cell biology of leukocyte-mediated proteolysis
-
Owen CA, Campbell EJ. The cell biology of leukocyte-mediated proteolysis. J Leukoc Biol 1999; 65: 137-150.
-
(1999)
J Leukoc Biol
, vol.65
, pp. 137-150
-
-
Owen, C.A.1
Campbell, E.J.2
-
20
-
-
0033215368
-
Extracellular proteolysis: New paradigms for an old paradox
-
Owen CA, Campbell EJ. Extracellular proteolysis: new paradigms for an old paradox. J Lab Clin Med 1999; 134: 341-351.
-
(1999)
J Lab Clin Med
, vol.134
, pp. 341-351
-
-
Owen, C.A.1
Campbell, E.J.2
-
21
-
-
0025359581
-
Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor
-
Rice WG, Weiss SJ. Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor. Science 1990; 249: 178-181.
-
(1990)
Science
, vol.249
, pp. 178-181
-
-
Rice, W.G.1
Weiss, S.J.2
-
22
-
-
84864014453
-
Genetically distinct subsets within ANCA-associated vasculitis
-
Lyons PA, Rayner TF, Trivedi S et al. Genetically distinct subsets within ANCA-associated vasculitis. N Engl J Med 2012; 367: 214-223.
-
(2012)
N Engl J Med
, vol.367
, pp. 214-223
-
-
Lyons, P.A.1
Rayner, T.F.2
Trivedi, S.3
-
23
-
-
80052478226
-
ANCA-associated vasculitis is linked to carriage of the Z allele of alpha(1) antitrypsin and its polymers
-
Morris H, Morgan MD, Wood AM et al. ANCA-associated vasculitis is linked to carriage of the Z allele of alpha(1) antitrypsin and its polymers. Ann Rheum Dis 2011; 70: 1851-1856.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1851-1856
-
-
Morris, H.1
Morgan, M.D.2
Wood, A.M.3
-
24
-
-
0035135617
-
Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants
-
Yang JJ, Preston GA, Pendergraft WF et al. Internalization of proteinase 3 is concomitant with endothelial cell apoptosis and internalization of myeloperoxidase with generation of intracellular oxidants. Am J Pathol 2001; 158: 581-592.
-
(2001)
Am J Pathol
, vol.158
, pp. 581-592
-
-
Yang, J.J.1
Preston, G.A.2
Pendergraft, W.F.3
-
25
-
-
84877112483
-
Beta2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells
-
Jerke U, Rolle S, Purfurst B et al. beta2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells. J Biol Chem 2013; 288: 12910-12919.
-
(2013)
J Biol Chem
, vol.288
, pp. 12910-12919
-
-
Jerke, U.1
Rolle, S.2
Purfurst, B.3
-
26
-
-
0034023795
-
Proteinase 3 interacts with a 111-kD membrane molecule of human umbilical vein endothelial cells
-
Taekema-Roelvink ME, Van Kooten C, Heemskerk E et al. Proteinase 3 interacts with a 111-kD membrane molecule of human umbilical vein endothelial cells. J Am Soc Nephrol 2000; 11: 640-648.
-
(2000)
J Am Soc Nephrol
, vol.11
, pp. 640-648
-
-
Taekema-Roelvink, M.E.1
Van Kooten, C.2
Heemskerk, E.3
-
27
-
-
84867407206
-
Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells
-
Gregory AD, Hale P, Perlmutter DH et al. Clathrin pit-mediated endocytosis of neutrophil elastase and cathepsin G by cancer cells. J Biol Chem 2012; 287: 35341-35350.
-
(2012)
J Biol Chem
, vol.287
, pp. 35341-35350
-
-
Gregory, A.D.1
Hale, P.2
Perlmutter, D.H.3
-
28
-
-
0035079801
-
Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes
-
Delgado MB, Clark-Lewis I, Loetscher P et al. Rapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes. Eur J Immunol 2001; 31: 699-707.
-
(2001)
Eur J Immunol
, vol.31
, pp. 699-707
-
-
Delgado, M.B.1
Clark-Lewis, I.2
Loetscher, P.3
-
29
-
-
0037013221
-
Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4
-
Valenzuela-Fernandez A, Planchenault T, Baleux F et al. Leukocyte elastase negatively regulates Stromal cell-derived factor-1 (SDF-1)/CXCR4 binding and functions by amino-terminal processing of SDF-1 and CXCR4. J Biol Chem 2002; 277: 15677-15689.
-
(2002)
J Biol Chem
, vol.277
, pp. 15677-15689
-
-
Valenzuela-Fernandez, A.1
Planchenault, T.2
Baleux, F.3
-
30
-
-
0030968521
-
Specific inhibition of thrombininduced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: Evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor
-
Renesto P, Si-Tahar M, Moniatte M et al. Specific inhibition of thrombininduced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor. Blood 1997; 89: 1944-1953.
-
(1997)
Blood
, vol.89
, pp. 1944-1953
-
-
Renesto, P.1
Si-Tahar, M.2
Moniatte, M.3
-
31
-
-
0031029215
-
Modulation of human endothelial thrombomodulin by neutrophils and their release products
-
MacGregor IR, Perrie AM, Donnelly SC et al. Modulation of human endothelial thrombomodulin by neutrophils and their release products. Am J Respir Crit Care Med 1997; 155: 47-52.
-
(1997)
Am J Respir Crit Care Med
, vol.155
, pp. 47-52
-
-
Macgregor, I.R.1
Perrie, A.M.2
Donnelly, S.C.3
-
32
-
-
0026825660
-
Mechanism of neutrophil-induced xanthine dehydrogenase to xanthine oxidase conversion in endothelial cells: Evidence of a role for elastase
-
Phan SH, Gannon DE, Ward PA et al. Mechanism of neutrophil-induced xanthine dehydrogenase to xanthine oxidase conversion in endothelial cells: evidence of a role for elastase. Am J Respir Cell Mol Biol 1992; 6: 270-278.
-
(1992)
Am J Respir Cell Mol Biol
, vol.6
, pp. 270-278
-
-
Phan, S.H.1
Gannon, D.E.2
Ward, P.A.3
-
33
-
-
0025719618
-
Inactivation of endothelin by polymorphonuclear leukocyte-derived lytic enzymes
-
Patrignani P, Del Maschio A, Bazzoni G et al. Inactivation of endothelin by polymorphonuclear leukocyte-derived lytic enzymes. Blood 1991; 78: 2715-2720.
-
(1991)
Blood
, vol.78
, pp. 2715-2720
-
-
Patrignani, P.1
Del Maschio, A.2
Bazzoni, G.3
-
34
-
-
0037853133
-
Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration
-
Hermant B, Bibert S, Concord E et al. Identification of proteases involved in the proteolysis of vascular endothelium cadherin during neutrophil transmigration. J Biol Chem 2003; 278: 14002-14012.
-
(2003)
J Biol Chem
, vol.278
, pp. 14002-14012
-
-
Hermant, B.1
Bibert, S.2
Concord, E.3
-
35
-
-
77951134556
-
Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics
-
Prudova A, auf dem Keller U, Butler GS et al. Multiplex N-terminome analysis of MMP-2 and MMP-9 substrate degradomes by iTRAQ-TAILS quantitative proteomics. Mol Cell Proteomics 2010; 9: 894-911.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 894-911
-
-
Prudova, A.1
Auf Dem Keller, U.2
Butler, G.S.3
-
36
-
-
84877887593
-
Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism
-
Wilson CH, Indarto D, Doucet A et al. Identifying natural substrates for dipeptidyl peptidases 8 and 9 using terminal amine isotopic labeling of substrates (TAILS) reveals in vivo roles in cellular homeostasis and energy metabolism. J Biol Chem 2013; 288: 13936-13949.
-
(2013)
J Biol Chem
, vol.288
, pp. 13936-13949
-
-
Wilson, C.H.1
Indarto, D.2
Doucet, A.3
-
37
-
-
70350732744
-
Improved visualization of protein consensus sequences by iceLogo
-
Colaert N, Helsens K, Martens L et al. Improved visualization of protein consensus sequences by iceLogo. Nat Methods 2009; 6: 786-787.
-
(2009)
Nat Methods
, vol.6
, pp. 786-787
-
-
Colaert, N.1
Helsens, K.2
Martens, L.3
-
38
-
-
44949142150
-
Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites
-
Schilling O, Overall CM. Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites. Nat Biotechnol 2008; 26: 685-694.
-
(2008)
Nat Biotechnol
, vol.26
, pp. 685-694
-
-
Schilling, O.1
Overall, C.M.2
-
39
-
-
84884477446
-
Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase
-
O'Donoghue AJ, Jin Y, Knudsen GM et al. Global substrate profiling of proteases in human neutrophil extracellular traps reveals consensus motif predominantly contributed by elastase. PloS one 2013; 8: e75141.
-
(2013)
PloS One
, vol.8
, pp. e75141
-
-
O'Donoghue, A.J.1
Jin, Y.2
Knudsen, G.M.3
-
41
-
-
79956322553
-
Global quantification of mammalian gene expression control
-
Schwanhausser B, Busse D, Li N et al. Global quantification of mammalian gene expression control. Nature 2011; 473: 337-342.
-
(2011)
Nature
, vol.473
, pp. 337-342
-
-
Schwanhausser, B.1
Busse, D.2
Li, N.3
-
42
-
-
0036433010
-
Kinetics of thrombomodulin release and endothelial cell injury by neutrophil-derived proteases and oxygen radicals
-
Boehme MW, Galle P, Stremmel W. Kinetics of thrombomodulin release and endothelial cell injury by neutrophil-derived proteases and oxygen radicals. Immunology 2002; 107: 340-349.
-
(2002)
Immunology
, vol.107
, pp. 340-349
-
-
Boehme, M.W.1
Galle, P.2
Stremmel, W.3
-
43
-
-
84865602319
-
Neutrophil serine proteases mediate inflammatory cell recruitment by glomerular endothelium and progression towards dysfunction
-
Kuravi SJ, Bevins A, Satchell SC et al. Neutrophil serine proteases mediate inflammatory cell recruitment by glomerular endothelium and progression towards dysfunction. Nephrol Dial Transplant 2012; 27: 4331-4338.
-
(2012)
Nephrol Dial Transplant
, vol.27
, pp. 4331-4338
-
-
Kuravi, S.J.1
Bevins, A.2
Satchell, S.C.3
-
44
-
-
8944225501
-
Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulphate after in vivo renal perfusion in rats
-
Heeringa P, Van den Born J, Brouwer E et al. Elastase, but not proteinase 3 (PR3), induces proteinuria associated with loss of glomerular basement membrane heparan sulphate after in vivo renal perfusion in rats. Clin Exp Immunol 1996; 105: 321-329.
-
(1996)
Clin Exp Immunol
, vol.105
, pp. 321-329
-
-
Heeringa, P.1
Van Den Born, J.2
Brouwer, E.3
-
45
-
-
33646487150
-
Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils
-
Lu X, Garfield A, Rainger GE et al. Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils. Arthritis Rheum 2006; 54: 1619-1628.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1619-1628
-
-
Lu, X.1
Garfield, A.2
Rainger, G.E.3
-
46
-
-
84911374663
-
New selective peptidyl di (chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases
-
Guarino C, Legowska M, Epinette C et al. New selective peptidyl di (chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases. J Biol Chem 2014; 289: 31777-31791.
-
(2014)
J Biol Chem
, vol.289
, pp. 31777-31791
-
-
Guarino, C.1
Legowska, M.2
Epinette, C.3
-
47
-
-
84923864234
-
Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN
-
Schreiber A, Luft FC, Kettritz R. Phagocyte NADPH oxidase restrains the inflammasome in ANCA-induced GN. J Am Soc Nephrol 2014; 26: 411-424.
-
(2014)
J Am Soc Nephrol
, vol.26
, pp. 411-424
-
-
Schreiber, A.1
Luft, F.C.2
Kettritz, R.3
-
48
-
-
44949182000
-
Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates
-
Korkmaz B, Attucci S, Juliano MA et al. Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates. Nat Protoc 2008; 3: 991-1000.
-
(2008)
Nat Protoc
, vol.3
, pp. 991-1000
-
-
Korkmaz, B.1
Attucci, S.2
Juliano, M.A.3
-
49
-
-
77956195339
-
Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis
-
Kuhl A, Korkmaz B, Utecht B et al. Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis. J Immunol 2010; 185: 387-399.
-
(2010)
J Immunol
, vol.185
, pp. 387-399
-
-
Kuhl, A.1
Korkmaz, B.2
Utecht, B.3
|