β2 integrin-mediated cell-cell contact transfers active myeloperoxidase from neutrophils to endothelial cells

Journal of Biological Chemistry

Volumn 288, Issue 18, 2013, Pages 12910-12919

  Jerke, Uwe ^a   Rolle, Susanne ^a   Purfürst, Bettina ^a   Luft, Friedrich C ^a   Nauseef, William M ^b,c   Kettritz, Ralph ^a,d  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b UNIVERSITY OF IOWA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL-CELL CONTACT; CONTACT SITES; DEGRANULATION; EXPOSURE-TIME; FLUORESCENT PROBES; INCUBATION TEMPERATURES; MYELOPEROXIDASE; VASCULITIS;

DISEASES; ELECTRON MICROSCOPY; FLOW CYTOMETRY;

ENDOTHELIAL CELLS;

CD11B ANTIGEN; CD18 ANTIGEN; ENDOTOXIN; MYELOPEROXIDASE;

ANIMAL CELL; ARTICLE; BLOCKING FACTOR; CELL CONTACT; CELL COUNT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DEGRANULATION; ELECTRON MICROSCOPY; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME RELEASE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; INCUBATION TEMPERATURE; INTERNALIZATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; TIME;

CELL-CELL INTERACTION; ENDOTHELIUM; INTEGRINS; MYELOPEROXIDASE; NEUTROPHIL; VASCULAR BIOLOGY;

ANIMALS; ANTIGENS, CD11B; ANTIGENS, CD18; ATHEROSCLEROSIS; CELL COMMUNICATION; CELL DEGRANULATION; COCULTURE TECHNIQUES; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIPOPOLYSACCHARIDES; MICE; MICE, KNOCKOUT; NEUTROPHILS; PEROXIDASE; PROTEIN TRANSPORT; VASCULITIS;

MUS;

EID: 84877112483     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.434613     Document Type: Article

References (33)

1. Agner, K. (1941) Verdoperoxidase: a ferment isolated from leukocytes. Acta Physiol. Scand. 2 (Suppl. 8), 1-62
2. Klebanoff, S. J., Kettle, A. J., Rosen, H., Winterbourn, C. C., and Nauseef, W. M. (2013) Myeloperoxidase: a front-line defender against phagocytosed microorganisms. J. Leukoc. Biol. 93, 185-198
3. Nauseef, W. M. (2007) How human neutrophils kill and degrade microbes: an integrated view. Immunol. Rev. 219, 88-102
4. Brennan, M. L., Penn, M. S., Van Lente, F., Nambi, V., Shishehbor, M. H., Aviles, R. J., Goormastic, M., Pepoy, M. L., McErlean, E. S., Topol, E. J., Nissen, S. E., and Hazen, S. L. (2003) Prognostic value of myeloperoxidase in patients with chest pain. N. Engl. J. Med. 349, 1595-1604 (Pubitemid 37288567)
5. Buffon, A., Biasucci, L. M., Liuzzo, G., D'Onofrio, G., Crea, F., and Maseri, A. (2002) Widespread coronary inflammation in unstable angina. N. Engl. J. Med. 347, 5-12 (Pubitemid 34728951)
6. Karakas, M., Koenig, W., Zierer, A., Herder, C., Rottbauer, W., Baumert, J., Meisinger, C., and Thorand, B. (2012) Myeloperoxidase is associated with incident coronary heart disease independently of traditional risk factors: results from the MONICA/KORA Augsburg study. J. Intern. Med. 271, 43-50
7. Kalantar-Zadeh, K., Brennan, M. L., and Hazen, S. L. (2006) Serum myeloperoxidase and mortality in maintenance hemodialysis patients. Am. J. Kidney Dis. 48, 59-68
8. Wang, A. Y., Lam, C. W., Chan, I. H., Wang, M., Lui, S. F., and Sanderson, J. E. (2010) Prognostic value of plasma myeloperoxidase in ESRD patients. Am. J. Kidney Dis. 56, 937-946
9. Eiserich, J. P., Baldus, S., Brennan, M. L., Ma, W., Zhang, C., Tousson, A., Castro, L., Lusis, A. J., Nauseef, W. M., White, C. R., and Freeman, B. A. (2002) Myeloperoxidase, a leukocyte-derived vascular NO oxidase. Science 296, 2391-2394 (Pubitemid 34734213)
10. Astern, J. M., Pendergraft, W. F., 3rd, Falk, R. J., Jennette, J. C., Schmaier, A. H., Mahdi, F., and Preston, G. A. (2007) Myeloperoxidase interacts with endothelial cell-surface cytokeratin 1 and modulates bradykinin production by the plasma kallikrein-kinin system. Am. J. Pathol. 171, 349-360 (Pubitemid 47339251)
11. McMillen, T. S., Heinecke, J. W., and LeBoeuf, R. C. (2005) Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice. Circulation 111, 2798-2804 (Pubitemid 40791552)
12. Klinke, A., Nussbaum, C., Kubala, L., Friedrichs, K., Rudolph, T. K., Rudolph, V., Paust, H. J., Schröder, C., Benten, D., Lau, D., Szocs, K., Furtmüller, P. G., Heeringa, P., Sydow, K., Duchstein, H. J., Ehmke, H., Schumacher, U., Meinertz, T., Sperandio, M., and Baldus, S. (2011) Myeloperoxidase attracts neutrophils by physical forces. Blood 117, 1350-1358
13. Rudolph, V., Andrié, R. P., Rudolph, T. K., Friedrichs, K., Klinke, A., Hirsch-Hoffmann, B., Schwoerer, A. P., Lau, D., Fu, X., Klingel, K., Sydow, K., Didié, M., Seniuk, A., von Leitner, E. C., Szoecs, K., Schrickel, J. W., Treede, H., Wenzel, U., Lewalter, T., Nickenig, G., Zimmermann, W. H., Meinertz, T., Böger, R. H., Reichenspurner, H., Freeman, B. A., Eschenhagen, T., Ehmke, H., Hazen, S. L., Willems, S., and Baldus, S. (2010) Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat. Med. 16, 470-474
14. Xiao, H., Heeringa, P., Hu, P., Liu, Z., Zhao, M., Aratani, Y., Maeda, N., Falk, R. J., and Jennette, J. C. (2002) Antineutrophil cytoplasmic autoantibodies specific for myeloperoxidase cause glomerulonephritis and vasculitis in mice. J. Clin. Invest. 110, 955-963
15. Segelmark, M., Persson, B., Hellmark, T., and Wieslander, J. (1997) Binding and inhibition of myeloperoxidase (MPO): a major function of ceruloplasmin? Clin. Exp. Immunol. 108, 167-174 (Pubitemid 27140345)
16. Chapman, A. L., Mocatta, T. J., Shiva, S., Seidel, A., Chen, B., Khalilova, I., Paumann-Page, M. E., Jameson, G. N., Winterbourn, C. C., and Kettle, A. J. (2013) Ceruloplasmin is an endogenous inhibitor of myeloperoxidase. J. Biol. Chem. 288, 6465-6477
17. Sengeløv, H., Kjeldsen, L., and Borregaard, N. (1993) Control of exocytosis in early neutrophil activation. J. Immunol. 150, 1535-1543 (Pubitemid 23127445)
18. Sengeløv, H., Follin, P., Kjeldsen, L., Lollike, K., Dahlgren, C., and Borregaard, N. (1995) Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils. J. Immunol. 154, 4157-4165
19. Essin, K., Gollasch, M., Rolle, S., Weissgerber, P., Sausbier, M., Bohn, E., Autenrieth, I. B., Ruth, P., Luft, F. C., Nauseef, W. M., and Kettritz, R. (2009) BK channels in innate immune functions of neutrophils and macrophages. Blood 113, 1326-1331
20. Uriarte, S. M., Rane, M. J., Luerman, G. C., Barati, M. T., Ward, R. A., Nauseef, W. M., and McLeish, K. R. (2011) Granule exocytosis contributes to priming and activation of the human neutrophil respiratory burst. J. Immunol. 187, 391-400
21. von Vietinghoff, S., Tunnemann, G., Eulenberg, C., Wellner, M., Cristina Cardoso, M., Luft, F. C., and Kettritz, R. (2007) NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils. Blood 109, 4487-4493 (Pubitemid 46743419)
22. Flemmig, J., Zschaler, J., Remmler, J., and Arnhold, J. (2012) The fluorescein-derived dye aminophenyl fluorescein is a suitable tool to detect hypobromous acid (HOBr)-producing activity in eosinophils. J. Biol. Chem. 287, 27913-27923
23. Bouma, M. G., Jeunhomme, T. M., Boyle, D. L., Dentener, M. A., Voitenok, N. N., van den Wildenberg, F. A., and Buurman, W. A. (1997) Adenosine inhibits neutrophil degranulation in activated human whole blood: involvement of adenosine A2 and A3 receptors. J. Immunol. 158, 5400-5408 (Pubitemid 127681247)
24. Meotti, F. C., Jameson, G. N., Turner, R., Harwood, D. T., Stockwell, S., Rees, M. D., Thomas, S. R., and Kettle, A. J. (2011) Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation. J. Biol. Chem. 286, 12901-12911
25. Zouaoui Boudjeltia, K., Moguilevsky, N., Legssyer, I., Babar, S., Guillaume, M., Delree, P., Vanhaeverbeek, M., Brohee, D., Ducobu, J., and Remacle, C. (2004) Oxidation of low density lipoproteins by myeloperoxidase at the surface of endothelial cells: an additional mechanism to subendothelium oxidation. Biochem. Biophys. Res. Commun. 325, 434-438 (Pubitemid 39458014)
26. Bergt, C., Pennathur, S., Fu, X., Byun, J., O'Brien, K., McDonald, T. O., Singh, P., Anantharamaiah, G. M., Chait, A., Brunzell, J., Geary, R. L., Oram, J. F., and Heinecke, J. W. (2004) The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. Proc. Natl. Acad. Sci. U.S.A. 101, 13032-13037 (Pubitemid 39167578)
27. Shock, A., and Baum, H. (1988) Inactivation of α1-proteinase inhibitor in serum by stimulated human polymorphonuclear leucocytes: evidence for a myeloperoxidase-dependent mechanism. Cell Biochem. Funct. 6, 13-23 (Pubitemid 18008105)
28. Lau, D., Mollnau, H., Eiserich, J. P., Freeman, B. A., Daiber, A., Gehling, U. M., Brümmer, J., Rudolph, V., Münzel, T., Heitzer, T., Meinertz, T., and Baldus, S. (2005) Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proc. Natl. Acad. Sci. U.S.A. 102, 431-436 (Pubitemid 40116784)
29. Horner, H., Frank, C., Dechant, C., Repp, R., Glennie, M., Herrmann, M., and Stockmeyer, B. (2007) Intimate cell conjugate formation and exchange of membrane lipids precede apoptosis induction in target cells during antibody-dependent, granulocyte-mediated cytotoxicity. J. Immunol. 179, 337-345 (Pubitemid 46986550)
30. van Spriel, A. B., Leusen, J. H., van Egmond, M., Dijkman, H. B., Assmann, K. J., Mayadas, T. N., and van de Winkel, J. G. (2001) Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation. Blood 97, 2478-2486 (Pubitemid 32291496)
31. Campbell, E. J., Senior, R. M., McDonald, J. A., and Cox, D. L. (1982) Proteolysis by neutrophils: relative importance of cell-substrate contact and oxidative inactivation of proteinase inhibitors in vitro. J. Clin. Invest. 70, 845-852 (Pubitemid 12038101)
32. Rice, W. G., and Weiss, S. J. (1990) Regulation of proteolysis at the neutrophil-substrate interface by secretory leukoprotease inhibitor. Science 249, 178-181
33. Loike, J. D., Silverstein, R., Wright, S. D., Weitz, J. I., Huang, A. J., and Silverstein, S. C. (1992) The role of protected extracellular compartments in interactions between leukocytes, and platelets, and fibrin/fibrinogen matrices. Ann. N.Y. Acad. Sci. 667, 163-172 (Pubitemid 23061574)