Modulation of human endothelial thrombomodulin by neutrophils and their release products

American Journal of Respiratory and Critical Care Medicine

Volumn 155, Issue 1, 1997, Pages 47-52

  Macgregor, Ian R ^a,b   Perrie, Ann Marie ^a   Donnelly, Seamas C ^a   Haslett, Christopher ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b SCOTTISH NATIONAL BLOOD TRANSFUSION SERVICE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN; HYDROGEN PEROXIDE; THROMBOMODULIN;

ADULT RESPIRATORY DISTRESS SYNDROME; ANTICOAGULATION; ARTICLE; CELL ACTIVITY; CELL SURFACE; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN TISSUE; LUNG BLOOD VESSEL; MICROVASCULATURE; NEUTROPHIL CHEMOTAXIS; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

EID: 0031029215     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.155.1.9001288     Document Type: Article

References (34)

1. Windsor, A. C. J., P.G. Mullen, and A. A. Fowler. 1993. Acute lung injury: what have we learned from animal models. Am. J. Med. Sci. 306:111-116.
2. McNaughton, P. D., and T. W. Evans. 1992. Management of adult respiratory distress syndrome. Lancet 339:469-472.
3. Repine, J. E. 1992. Scientific perspectives on adult respiratory distress syndrome. Lancet 339:466-469.
4. Donnelly, S. C., I. R. MacGregor, A. Zamani, M. W. G. Gordon, C. E. Robertson, D. J. Steedman, K. Little, and C. Haslett. 1995. Plasma elastase levels and the development of the adult respiratory distress syndrome (ARDS). Am. J. Respir. Crit. Care Med. 151:1428-1433.
5. Donnelly, S. C., C. Haslett, I. Dransfield, C. E. Robertson, D. C. Carter, J. A. Ross, I. S. Grant, and T. F. Tedder. 1994. Role of selectins in development of adult respiratory distress syndrome. Lancet 344: 215-219.
6. Donnelly, S. C., R. M. Streiter, S. L. Kunkel, A. Walz, C. R. Robertson, D. C. Carter, I. S. Grant, A. J. Pollok, and C. Haslett. 1993. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 341:643-647.
7. Moss, M., L. Ackerson, M. K. Gillespie, F. A. Moore, E. E. Moore, and P. E. Parsons. 1995. Von Willebrand factor antigen levels are not predictive for the adult respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 151:15-20.
8. Ruggeri, Z. M., and J. Ware. 1993. Von Willebrand factor. F.A.S.E.B. J. 7:308-316.
9. Basran, G. S., and J. G. Hardy. 1988. Monitoring pulmonary vascular permeability using radiolabelled transferrin. J. Thorac. Imaging 3: 25-35.
10. Basran, G. S., A. J. Byrne, and J. G. Hardy. 1985. Lung leak assessment using radiolabelled proteins imaging: a non-invasive method for monitoring lung vascular permeability in man. Nucl. Med. Commun. 6:3-10.
11. Takano, S., S. Kimura, S. Ohdama, and N. Aoki. 1990. Plasma thrombomodulin in health and diseases. Blood 76:2024-2029.
12. Esmon, C. T. 1993. Molecular events that control the protein-C anticoagulant pathway. Thromb. Haemost. 70:29-35.
13. Dittman, W. A., and P. W. Majerus. 1990. Structure and function of thrombomodulin: a natural anticoagulant. Blood 75:329-336.
14. Dittman, W. A. 1991. Thrombomodulin: biology and potential cardiovascular applications. Trends Cardiovasc. Med. 1:331-336.
15. Sawada, K., H. Yamamoto, K. Matsumoto, H. Yago, S. Suehiro, C. Tahara, H. Ishii, M. Kazama, and T. Abe. 1992. Changes in thrombomodulin level in plasma of endotoxin-infused rabbits. Thromb. Res. 65:199-209.
16. Sawada, K., H. Yamamoto, H. Yago, and S. Suehiro. 1992. A simple assay to detect endothelial cell injury: measurement of released thrombomodulin from cells. Exp. Mol. Pathol. 57:116-123.
17. Abe, H., K. Okajima, H. Okabe, K. Takatsuki, and B. R. Binder. 1994. Granulocyte proteases and hydrogen peroxide synergistically inactivate thrombomodulin of endothelial cells in vitro. J. Lab. Clin. Med. 123:874-881.
18. Glaser, C. B., J. Morser, J. H. Clarke, E. Blasko, K. Mclean, I. Kuhn, R. J. Chang, J. H. Lin, L. Vilander, W. H. Andrews, and D. R. Light. 1992. Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity: a potential rapid mechanism for modulation of coagulation. J. Clin. Invest. 90:2565-2573.
19. Murray, J. F., M. A. Matthey, J. M. Luce, and M. R. Flick. 1988. An expanded definition of the adult respiratory distress syndrome Am. Rev. Respir. Dis. 138:720-723.
20. Jaffe, E. A., R. L. Nachman, C. G. Becker, and C. R. Minick. 1993. Culture of human endothelial cells derived from umbilical vein. J. Clin. Invest. 52:2746-2756.
21. Hunter, N. R., J. Dawes, I. R. MacGregor, and D. S. Pepper. 1984. Quantitation by radioimmunoassay of thrombospondin synthesised and secreted by human endothelial cells. Thromb. Haemost. 52:288-291.
22. Haslett, C., L. A. Guthrie, M. M. Kopaniak, R. B. Johnston, and P. M. Henson. 1985. Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide. Am. J. Pathol. 119:101-110.
23. Smedly, L. A., M. G. Tonnesen, R. A. Sandhaus, C. Haslett, L. A. Guthrie, and R. B. Johnstone, Jr. 1986. Neutrophil-mediated injury to endothelial cells: enhancement by endotoxin and essential role of neutrophil elastase. J. Clin. Invest. 77:1233-1243.
24. Archipoff, G., A. Beretz, J. M. Freyssinet, C. Klein Soyer, C. Brisson, and J. P. Cazenave. 1991. Heterogeneous regulation of constitutive thrombomodulin or inducible tissue-factor activities on the surface of human saphenous-vein endothelial cells in culture following stimulation by interleukin-1, tumour necrosis factor, thrombin or phorbol ester. Biochem. J. 273:679-684.
25. Amiral, J., M. Adam, F. Mimilla, I. Larrivaz, B. Chambrette, and M. C. Boffa. 1994. Design and validation of a new immunoassay for soluble forms of thrombomodulin and studies on plasma. Hybridoma 13:205-213.
26. Hirokawa, K., and N. Aoki. 1991. Regulatory mechanisms for thrombomodulin expression in human umbilical vein endothelial cells in vitro. J. Cell. Physiol. 147:157-165.
27. Lentz, S. R., M. Tsiang, and J. E. Sadler. 1991. Regulation of thrombomodulin by tumor necrosis factor-alpha: comparison of transcriptional and posttranscriptional mechanisms. Blood 77:542-550.
28. Asselbergs, F. A. M., R. Burgi, J. Hamerman, J. Heim, J. Vanoostrum, and G. Agnelli. 1993. A hybrid plasminogen activator binds to the u-PA receptor and has a reduced thrombolytic potency in vivo. Thromb. Haemost. 69:50-55.
29. Ishii, H., H. Uchiyama, and M. Kazama. 1991. Soluble thrombomodulin antigen in conditioned medium is increased by damage of endothelial cells. Thromb. Haemost. 65:618-623.
30. Key, N. S., J. L. Platt, and G. M. Vercellotti. 1992. Vascular endothelial cell proteoglycans are susceptible to cleavage by neutrophils. Arterioscler. Thromb. 12:836-842.
31. Slungaard, A., G. M. Vercellotti, T. Tran, G. J. Gleich, N. S. Key. 1993. Eosinophil cationic granule proteins impair thrombomodulin function. J. Clin. Invest. 91:1721-1730.
32. Kurosawa, S., J. B. Galvin, N. L. Esmon, and C. T. Esmon. 1987. Proteolytic formation and properties of functional domains of thrombomodulin. J. Biol. Chem. 262:2206-2212.
33. Kimura, S., T. Nagoya, and N. Aoki. 1989. Monoclonal antibodies to human thrombomodulin whose binding is calcium dependent. J. Biochem. (Tokyo) 105:478-483.
34. Bauer, K. A., B. L. Kass, D. L. Beeler, and R. D. Rosenberg. 1984. Detection of protein C activation in humans. J. Clin Invest. 74: 2033-2041.