-
1
-
-
14844353173
-
Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils
-
Sengelov H, Follin P, Kjeldsen L, Lollike K, Dahlgren C, Borregaard N. Mobilization of granules and secretory vesicles during in vivo exudation of human neutrophils. J Immunol 1995; 154:4157-65.
-
(1995)
J Immunol
, vol.154
, pp. 4157-4165
-
-
Sengelov, H.1
Follin, P.2
Kjeldsen, L.3
Lollike, K.4
Dahlgren, C.5
Borregaard, N.6
-
2
-
-
0027174208
-
Control of exocytosis in early neutrophil activation
-
Sengelov H, Kjeldsen L, Borregaard N. Control of exocytosis in early neutrophil activation. J Immunol 1993; 150:1535-43.
-
(1993)
J Immunol
, vol.150
, pp. 1535-1543
-
-
Sengelov, H.1
Kjeldsen, L.2
Borregaard, N.3
-
3
-
-
0033214847
-
Presence of proteinase 3 in secretory vesicles: evidence of a novel, highly mobilizable intracellular pool distinct from azurophil granules
-
Witko Sarsat V, Cramer EM, Hieblot C etal. Presence of proteinase 3 in secretory vesicles: evidence of a novel, highly mobilizable intracellular pool distinct from azurophil granules. Blood 1999; 94:2487-96.
-
(1999)
Blood
, vol.94
, pp. 2487-2496
-
-
Witko Sarsat, V.1
Cramer, E.M.2
Hieblot, C.3
-
4
-
-
0025345612
-
Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro
-
Falk RJ, Terrell RS, Charles LA, Jennette JC. Anti-neutrophil cytoplasmic autoantibodies induce neutrophils to degranulate and produce oxygen radicals in vitro. Proc Natl Acad Sci USA 1990; 87:4115-19.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 4115-4119
-
-
Falk, R.J.1
Terrell, R.S.2
Charles, L.A.3
Jennette, J.C.4
-
5
-
-
0025934581
-
Antibodies against granule proteins activate neutrophils in vitro
-
Charles LA, Caldas ML, Falk RJ, Terrell RS, Jennette JC. Antibodies against granule proteins activate neutrophils in vitro. J Leukoc Biol 1991; 50:539-46.
-
(1991)
J Leukoc Biol
, vol.50
, pp. 539-546
-
-
Charles, L.A.1
Caldas, M.L.2
Falk, R.J.3
Terrell, R.S.4
Jennette, J.C.5
-
6
-
-
59949101550
-
C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis
-
Schreiber A, Xiao H, Jennette JC, Schneider W, Luft FC, Kettritz R. C5a receptor mediates neutrophil activation and ANCA-induced glomerulonephritis. J Am Soc Nephrol 2009; 20:289-98.
-
(2009)
J Am Soc Nephrol
, vol.20
, pp. 289-298
-
-
Schreiber, A.1
Xiao, H.2
Jennette, J.C.3
Schneider, W.4
Luft, F.C.5
Kettritz, R.6
-
7
-
-
31544480105
-
IL-18 is upregulated in the kidney and primes neutrophil responsiveness in ANCA-associated vasculitis
-
Hewins P, Morgan MD, Holden N etal. IL-18 is upregulated in the kidney and primes neutrophil responsiveness in ANCA-associated vasculitis. Kidney Int 2006; 69:605-15.
-
(2006)
Kidney Int
, vol.69
, pp. 605-615
-
-
Hewins, P.1
Morgan, M.D.2
Holden, N.3
-
8
-
-
0028307148
-
Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo
-
Csernok E, Ernst M, Schmitt W, Bainton DF, Gross WL. Activated neutrophils express proteinase 3 on their plasma membrane in vitro and in vivo. Clin Exp Immunol 1994; 95:244-50.
-
(1994)
Clin Exp Immunol
, vol.95
, pp. 244-250
-
-
Csernok, E.1
Ernst, M.2
Schmitt, W.3
Bainton, D.F.4
Gross, W.L.5
-
9
-
-
0027141424
-
Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides
-
Csernok E, Schmitt WH, Ernst M, Bainton DF, Gross WL. Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides. Adv Exp Med Biol 1993; 336:45-50.
-
(1993)
Adv Exp Med Biol
, vol.336
, pp. 45-50
-
-
Csernok, E.1
Schmitt, W.H.2
Ernst, M.3
Bainton, D.F.4
Gross, W.L.5
-
10
-
-
34547619575
-
Increased membrane expression of proteinase 3 during neutrophil adhesion in the presence of anti proteinase 3 antibodies
-
Brachemi S, Mambole A, Fakhouri F etal. Increased membrane expression of proteinase 3 during neutrophil adhesion in the presence of anti proteinase 3 antibodies. J Am Soc Nephrol 2007; 18:2330-9.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2330-2339
-
-
Brachemi, S.1
Mambole, A.2
Fakhouri, F.3
-
11
-
-
80052478226
-
ANCA-associated vasculitis is linked to carriage of the Z allele of alpha antitrypsin and its polymers
-
Morris H, Morgan MD, Wood AM etal. ANCA-associated vasculitis is linked to carriage of the Z allele of alpha antitrypsin and its polymers. Ann Rheum Dis 2011; 70:1851-6.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1851-1856
-
-
Morris, H.1
Morgan, M.D.2
Wood, A.M.3
-
12
-
-
0028790701
-
Bimodal distribution of proteinase 3 (PR3) surface expression reflects a constitutive heterogeneity in the polymorphonuclear neutrophil pool
-
Halbwachs-Mecarelli L, Bessou G, Lesavre P, Lopez S, Witko-Sarsat V. Bimodal distribution of proteinase 3 (PR3) surface expression reflects a constitutive heterogeneity in the polymorphonuclear neutrophil pool. FEBS Lett 1995; 374:29-33.
-
(1995)
FEBS Lett
, vol.374
, pp. 29-33
-
-
Halbwachs-Mecarelli, L.1
Bessou, G.2
Lesavre, P.3
Lopez, S.4
Witko-Sarsat, V.5
-
14
-
-
33750734363
-
Major histocompatibility complex HLA region largely explains the genetic variance exercised on neutrophil membrane proteinase 3 expression
-
von Vietinghoff S, Busjahn A, Schonemann C etal. Major histocompatibility complex HLA region largely explains the genetic variance exercised on neutrophil membrane proteinase 3 expression. J Am Soc Nephrol 2006; 17:3185-91.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 3185-3191
-
-
von Vietinghoff, S.1
Busjahn, A.2
Schonemann, C.3
-
15
-
-
0032991087
-
A large subset of neutrophils expressing membrane proteinase 3 is a risk factor for vasculitis and rheumatoid arthritis
-
Witko-Sarsat V, Lesavre P, Lopez S etal. A large subset of neutrophils expressing membrane proteinase 3 is a risk factor for vasculitis and rheumatoid arthritis. J Am Soc Nephrol 1999; 10:1224-33.
-
(1999)
J Am Soc Nephrol
, vol.10
, pp. 1224-1233
-
-
Witko-Sarsat, V.1
Lesavre, P.2
Lopez, S.3
-
16
-
-
0036707876
-
Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis
-
Rarok AA, Stegeman CA, Limburg PC, Kallenberg CGM. Neutrophil membrane expression of proteinase 3 (PR3) is related to relapse in PR3-ANCA-associated vasculitis. J Am Soc Nephrol 2002; 13:2232-8.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 2232-2238
-
-
Rarok, A.A.1
Stegeman, C.A.2
Limburg, P.C.3
Kallenberg, C.G.M.4
-
17
-
-
27744467907
-
Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils
-
Schreiber A, Otto B, Ju X etal. Membrane proteinase 3 expression in patients with Wegener's granulomatosis and in human hematopoietic stem cell-derived neutrophils. J Am Soc Nephrol 2005; 16:2216-24.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2216-2224
-
-
Schreiber, A.1
Otto, B.2
Ju, X.3
-
18
-
-
2442656372
-
Membrane proteinase 3 expression and ANCA-induced neutrophil activation
-
Schreiber A, Luft FC, Kettritz R. Membrane proteinase 3 expression and ANCA-induced neutrophil activation. Kidney Int 2004; 65:2172-83.
-
(2004)
Kidney Int
, vol.65
, pp. 2172-2183
-
-
Schreiber, A.1
Luft, F.C.2
Kettritz, R.3
-
19
-
-
44349095833
-
Computational prediction of the binding site of proteinase 3 to the plasma membrane
-
Hajjar E, Mihajlovic M, Witko-Sarsat V, Lazaridis T, Reuter N. Computational prediction of the binding site of proteinase 3 to the plasma membrane. Proteins 2008; 71:1655-69.
-
(2008)
Proteins
, vol.71
, pp. 1655-1669
-
-
Hajjar, E.1
Mihajlovic, M.2
Witko-Sarsat, V.3
Lazaridis, T.4
Reuter, N.5
-
20
-
-
80055082814
-
Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener's autoantigen, in RBL cells: implication for its pathogenic activity
-
Kantari C, Millet A, Gabillet J etal. Molecular analysis of the membrane insertion domain of proteinase 3, the Wegener's autoantigen, in RBL cells: implication for its pathogenic activity. J Leukoc Biol 2011; 90:941-50.
-
(2011)
J Leukoc Biol
, vol.90
, pp. 941-950
-
-
Kantari, C.1
Millet, A.2
Gabillet, J.3
-
21
-
-
33846699482
-
Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils
-
Bauer S, Abdgawad M, Gunnarsson L, Segelmark M, Tapper H, Hellmark T. Proteinase 3 and CD177 are expressed on the plasma membrane of the same subset of neutrophils. J Leukoc Biol 2007; 81:458-64.
-
(2007)
J Leukoc Biol
, vol.81
, pp. 458-464
-
-
Bauer, S.1
Abdgawad, M.2
Gunnarsson, L.3
Segelmark, M.4
Tapper, H.5
Hellmark, T.6
-
22
-
-
34248385300
-
NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils
-
von Vietinghoff S, Tunnemann G, Eulenberg C etal. NB1 mediates surface expression of the ANCA antigen proteinase 3 on human neutrophils. Blood 2007; 109:4487-93.
-
(2007)
Blood
, vol.109
, pp. 4487-4493
-
-
von Vietinghoff, S.1
Tunnemann, G.2
Eulenberg, C.3
-
23
-
-
43349095267
-
Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing
-
von Vietinghoff S, Eulenberg C, Wellner M, Luft FC, Kettritz R. Neutrophil surface presentation of the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal processing. Clin Exp Immunol 2008; 152:508-16.
-
(2008)
Clin Exp Immunol
, vol.152
, pp. 508-516
-
-
von Vietinghoff, S.1
Eulenberg, C.2
Wellner, M.3
Luft, F.C.4
Kettritz, R.5
-
24
-
-
58149096975
-
A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors
-
Korkmaz B, Kuhl A, Bayat B, Santoso S, Jenne DE. A hydrophobic patch on proteinase 3, the target of autoantibodies in Wegener granulomatosis, mediates membrane binding via NB1 receptors. J Biol Chem 2008; 283:35976-82.
-
(2008)
J Biol Chem
, vol.283
, pp. 35976-35982
-
-
Korkmaz, B.1
Kuhl, A.2
Bayat, B.3
Santoso, S.4
Jenne, D.E.5
-
25
-
-
77954652310
-
The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction
-
Choi M, Eulenberg C, Rolle S, von Kries JP, Luft FC, Kettritz R. The use of small molecule high-throughput screening to identify inhibitors of the proteinase 3-NB1 interaction. Clin Exp Immunol 2010; 161:389-96.
-
(2010)
Clin Exp Immunol
, vol.161
, pp. 389-396
-
-
Choi, M.1
Eulenberg, C.2
Rolle, S.3
von Kries, J.P.4
Luft, F.C.5
Kettritz, R.6
-
26
-
-
77956195339
-
Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis
-
Kuhl A, Korkmaz B, Utecht B etal. Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis. J Immunol 2010; 185:387-99.
-
(2010)
J Immunol
, vol.185
, pp. 387-399
-
-
Kuhl, A.1
Korkmaz, B.2
Utecht, B.3
-
27
-
-
66049102208
-
Coexpression of CD177 and membrane proteinase 3 on neutrophils in antineutrophil cytoplasmic autoantibody-associated systemic vasculitis: anti-proteinase 3-mediated neutrophil activation is independent of the role of CD177-expressing neutrophils
-
Hu N, Westra J, Huitema MG etal. Coexpression of CD177 and membrane proteinase 3 on neutrophils in antineutrophil cytoplasmic autoantibody-associated systemic vasculitis: anti-proteinase 3-mediated neutrophil activation is independent of the role of CD177-expressing neutrophils. Arthritis Rheum 2009; 60:1548-57.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 1548-1557
-
-
Hu, N.1
Westra, J.2
Huitema, M.G.3
-
28
-
-
84920235395
-
Autoantibodies against neutrophils and monocytes: tool for diagnosis and marker for disease activity in Wegener's granulomatosis
-
van der Woude FJ, Rasmussen N, Lobatto S etal. Autoantibodies against neutrophils and monocytes: tool for diagnosis and marker for disease activity in Wegener's granulomatosis. Lancet 1985; i:425-9.
-
(1985)
Lancet
, vol.1
, pp. 425-429
-
-
van der Woude, F.J.1
Rasmussen, N.2
Lobatto, S.3
-
29
-
-
15044352818
-
Antineutrophil cytoplasmic autoantibodies penetrate into human polymorphonuclear leukocytes and modify their apoptosis
-
Deutsch M, Guejes L, Zurgil N etal. Antineutrophil cytoplasmic autoantibodies penetrate into human polymorphonuclear leukocytes and modify their apoptosis. Clin Exp Rheumatol 2004; 22:S35-40.
-
(2004)
Clin Exp Rheumatol
, vol.22
-
-
Deutsch, M.1
Guejes, L.2
Zurgil, N.3
-
30
-
-
3543052882
-
Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis
-
Yang JJ, Pendergraft WF, Alcorta DA etal. Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis. J Am Soc Nephrol 2004; 15:2103-14.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 2103-2114
-
-
Yang, J.J.1
Pendergraft, W.F.2
Alcorta, D.A.3
-
31
-
-
77956370874
-
Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis
-
Ciavatta DJ, Yang J, Preston GA etal. Epigenetic basis for aberrant upregulation of autoantigen genes in humans with ANCA vasculitis. J Clin Invest 2010; 120:3209-19.
-
(2010)
J Clin Invest
, vol.120
, pp. 3209-3219
-
-
Ciavatta, D.J.1
Yang, J.2
Preston, G.A.3
-
32
-
-
0028939428
-
A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells
-
Kain R, Matsui K, Exner M etal. A novel class of autoantigens of anti-neutrophil cytoplasmic antibodies in necrotizing and crescentic glomerulonephritis: the lysosomal membrane glycoprotein h-lamp-2 in neutrophil granulocytes and a related membrane protein in glomerular endothelial cells. J Exp Med 1995; 181:585-97.
-
(1995)
J Exp Med
, vol.181
, pp. 585-597
-
-
Kain, R.1
Matsui, K.2
Exner, M.3
-
33
-
-
53549100724
-
Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis
-
Kain R, Exner M, Brandes R etal. Molecular mimicry in pauci-immune focal necrotizing glomerulonephritis. Nat Med 2008; 14:1088-96.
-
(2008)
Nat Med
, vol.14
, pp. 1088-1096
-
-
Kain, R.1
Exner, M.2
Brandes, R.3
-
34
-
-
0024245391
-
Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan
-
Carlsson SR, Roth J, Piller F, Fukuda M. Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2. Major sialoglycoproteins carrying polylactosaminoglycan. J Biol Chem 1988; 263:18911-19.
-
(1988)
J Biol Chem
, vol.263
, pp. 18911-18919
-
-
Carlsson, S.R.1
Roth, J.2
Piller, F.3
Fukuda, M.4
-
35
-
-
84863230295
-
Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis
-
Roth AJ, Brown MC, Smith RN etal. Anti-LAMP-2 antibodies are not prevalent in patients with antineutrophil cytoplasmic autoantibody glomerulonephritis. J Am Soc Nephrol 2012; 23:545-55.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 545-555
-
-
Roth, A.J.1
Brown, M.C.2
Smith, R.N.3
-
36
-
-
84863393655
-
High prevalence of autoantibodies to hLAMP-2 in anti-neutrophil cytoplasmic antibody-associated vasculitis
-
Kain R, Tadema H, McKinney EF etal. High prevalence of autoantibodies to hLAMP-2 in anti-neutrophil cytoplasmic antibody-associated vasculitis. J Am Soc Nephrol 2012; 23:556-66.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 556-566
-
-
Kain, R.1
Tadema, H.2
McKinney, E.F.3
-
37
-
-
84857981209
-
Anti-LAMP-2 autoantibodies in ANCA-associated pauci-immune glomerulonephritis
-
Flint SM, Savage CO. Anti-LAMP-2 autoantibodies in ANCA-associated pauci-immune glomerulonephritis. J Am Soc Nephrol 2012; 23:378-80.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 378-380
-
-
Flint, S.M.1
Savage, C.O.2
-
38
-
-
0031093277
-
Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils
-
Kettritz R, Jennette JC, Falk RJ. Crosslinking of ANCA-antigens stimulates superoxide release by human neutrophils. J Am Soc Nephrol 1997; 8:386-94.
-
(1997)
J Am Soc Nephrol
, vol.8
, pp. 386-394
-
-
Kettritz, R.1
Jennette, J.C.2
Falk, R.J.3
-
39
-
-
0026480849
-
Activation of normal neutrophils by anti-neutrophil cytoplasm antibodies
-
Keogan MT, Esnault VL, Green AJ, Lockwood CM, Brown DL. Activation of normal neutrophils by anti-neutrophil cytoplasm antibodies. Clin Exp Immunol 1992; 90:228-34.
-
(1992)
Clin Exp Immunol
, vol.90
, pp. 228-234
-
-
Keogan, M.T.1
Esnault, V.L.2
Green, A.J.3
Lockwood, C.M.4
Brown, D.L.5
-
40
-
-
0028278370
-
Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa
-
Porges AJ, Redecha PB, Kimberly WT, Csernok E, Gross WL, Kimberly RP. Anti-neutrophil cytoplasmic antibodies engage and activate human neutrophils via Fc gamma RIIa. J Immunol 1994; 153:1271-80.
-
(1994)
J Immunol
, vol.153
, pp. 1271-1280
-
-
Porges, A.J.1
Redecha, P.B.2
Kimberly, W.T.3
Csernok, E.4
Gross, W.L.5
Kimberly, R.P.6
-
41
-
-
0028075480
-
Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA): a Fc gamma RII-dependent process
-
Mulder AH, Heeringa P, Brouwer E, Limburg PC, Kallenberg CG. Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA): a Fc gamma RII-dependent process. Clin Exp Immunol 1994; 98:270-8.
-
(1994)
Clin Exp Immunol
, vol.98
, pp. 270-278
-
-
Mulder, A.H.1
Heeringa, P.2
Brouwer, E.3
Limburg, P.C.4
Kallenberg, C.G.5
-
42
-
-
0028841383
-
Effect of tumor necrosis factor-induced integrin activation on Fc gamma receptor II-mediated signal transduction: relevance for activation of neutrophils by anti-proteinase 3 or anti-myeloperoxidase antibodies
-
Reumaux D, Vossebeld PJ, Roos D, Verhoeven AJ. Effect of tumor necrosis factor-induced integrin activation on Fc gamma receptor II-mediated signal transduction: relevance for activation of neutrophils by anti-proteinase 3 or anti-myeloperoxidase antibodies. Blood 1995; 86:3189-95.
-
(1995)
Blood
, vol.86
, pp. 3189-3195
-
-
Reumaux, D.1
Vossebeld, P.J.2
Roos, D.3
Verhoeven, A.J.4
-
43
-
-
0037372710
-
Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG
-
Williams JM, Ben-Smith A, Hewins P etal. Activation of the G(i) heterotrimeric G protein by ANCA IgG F(ab')2 fragments is necessary but not sufficient to stimulate the recruitment of those downstream mediators used by intact ANCA IgG. J Am Soc Nephrol 2003; 14:661-9.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 661-669
-
-
Williams, J.M.1
Ben-Smith, A.2
Hewins, P.3
-
44
-
-
18644368703
-
Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibodies (ANCA)
-
Yang JJ, Preston GA, Alcorta DA etal. Expression profile of leukocyte genes activated by anti-neutrophil cytoplasmic autoantibodies (ANCA). Kidney Int 2002; 62:1638-49.
-
(2002)
Kidney Int
, vol.62
, pp. 1638-1649
-
-
Yang, J.J.1
Preston, G.A.2
Alcorta, D.A.3
-
45
-
-
0034945665
-
Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro
-
Weidner S, Neupert W, Goppelt-Struebe M, Rupprecht HD. Antineutrophil cytoplasmic antibodies induce human monocytes to produce oxygen radicals in vitro. Arthritis Rheum 2001; 44:1698-706.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1698-1706
-
-
Weidner, S.1
Neupert, W.2
Goppelt-Struebe, M.3
Rupprecht, H.D.4
-
46
-
-
0032534578
-
Antineutrophil cytoplasmic antibodies preferentially engage Fc gammaRIIIb on human neutrophils
-
Kocher M, Edberg JC, Fleit HB, Kimberly RP. Antineutrophil cytoplasmic antibodies preferentially engage Fc gammaRIIIb on human neutrophils. J Immunol 1998; 161:6909-14.
-
(1998)
J Immunol
, vol.161
, pp. 6909-6914
-
-
Kocher, M.1
Edberg, J.C.2
Fleit, H.B.3
Kimberly, R.P.4
-
47
-
-
79953800630
-
Immunoglobulin subclass determines ability of immunoglobulin (Ig)G to capture and activate neutrophils presented as normal human IgG or disease-associated anti-neutrophil cytoplasm antibody (ANCA)-IgG
-
Pankhurst T, Nash G, Williams J, Colman R, Hussain A, Savage C. Immunoglobulin subclass determines ability of immunoglobulin (Ig)G to capture and activate neutrophils presented as normal human IgG or disease-associated anti-neutrophil cytoplasm antibody (ANCA)-IgG. Clin Exp Immunol 2011; 164:218-26.
-
(2011)
Clin Exp Immunol
, vol.164
, pp. 218-226
-
-
Pankhurst, T.1
Nash, G.2
Williams, J.3
Colman, R.4
Hussain, A.5
Savage, C.6
-
48
-
-
0025852122
-
IgG subclass distribution of autoantibodies to neutrophil cytoplasmic antigens in systemic vasculitis
-
Jayne DR, Weetman AP, Lockwood CM. IgG subclass distribution of autoantibodies to neutrophil cytoplasmic antigens in systemic vasculitis. Clin Exp Immunol 1991; 84:476-81.
-
(1991)
Clin Exp Immunol
, vol.84
, pp. 476-481
-
-
Jayne, D.R.1
Weetman, A.P.2
Lockwood, C.M.3
-
49
-
-
84862956330
-
IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis
-
Kelley JM, Monach PA, Ji C etal. IgA and IgG antineutrophil cytoplasmic antibody engagement of Fc receptor genetic variants influences granulomatosis with polyangiitis. Proc Natl Acad Sci USA 2011; 108:20736-41.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 20736-20741
-
-
Kelley, J.M.1
Monach, P.A.2
Ji, C.3
-
50
-
-
33947203686
-
FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA
-
Wu J, Ji C, Xie F etal. FcalphaRI (CD89) alleles determine the proinflammatory potential of serum IgA. J Immunol 2007; 178:3973-82.
-
(2007)
J Immunol
, vol.178
, pp. 3973-3982
-
-
Wu, J.1
Ji, C.2
Xie, F.3
-
51
-
-
79959817309
-
Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's)
-
Espy C, Morelle W, Kavian N etal. Sialylation levels of anti-proteinase 3 antibodies are associated with the activity of granulomatosis with polyangiitis (Wegener's). Arthritis Rheum 2011; 63:2105-15.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 2105-2115
-
-
Espy, C.1
Morelle, W.2
Kavian, N.3
-
53
-
-
0347361648
-
Interaction of proteinase 3 with CD11b/CD18 (beta2 integrin) on the cell membrane of human neutrophils
-
David A, Kacher Y, Specks U, Aviram I. Interaction of proteinase 3 with CD11b/CD18 (beta2 integrin) on the cell membrane of human neutrophils. J Leukoc Biol 2003; 74:551-7.
-
(2003)
J Leukoc Biol
, vol.74
, pp. 551-557
-
-
David, A.1
Kacher, Y.2
Specks, U.3
Aviram, I.4
-
54
-
-
22144435486
-
The presence of membrane Proteinase 3 in neutrophil lipid rafts and its colocalization with FcgammaRIIIb and cytochrome b558
-
David A, Fridlich R, Aviram I. The presence of membrane Proteinase 3 in neutrophil lipid rafts and its colocalization with FcgammaRIIIb and cytochrome b558. Exp Cell Res 2005; 308:156-65.
-
(2005)
Exp Cell Res
, vol.308
, pp. 156-165
-
-
David, A.1
Fridlich, R.2
Aviram, I.3
-
55
-
-
79953230880
-
Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation
-
Jerke U, Rolle S, Dittmar G etal. Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation. J Biol Chem 2011; 286:7070-81.
-
(2011)
J Biol Chem
, vol.286
, pp. 7070-7081
-
-
Jerke, U.1
Rolle, S.2
Dittmar, G.3
-
56
-
-
0034667675
-
Induction of neutrophil responsiveness to myeloperoxidase antibodies by their exposure to supernatant of degranulated autologous neutrophils
-
Hess C, Sadallah S, Schifferli JA. Induction of neutrophil responsiveness to myeloperoxidase antibodies by their exposure to supernatant of degranulated autologous neutrophils. Blood 2000; 96:2822-7.
-
(2000)
Blood
, vol.96
, pp. 2822-2827
-
-
Hess, C.1
Sadallah, S.2
Schifferli, J.A.3
-
57
-
-
0030920656
-
Myeloperoxidase mediates cell adhesion via the alpha M beta 2 integrin (Mac-1, CD11b/CD18)
-
Johansson MW, Patarroyo M, Oberg F, Siegbahn A, Nilsson K. Myeloperoxidase mediates cell adhesion via the alpha M beta 2 integrin (Mac-1, CD11b/CD18). J Cell Sci 1997; 110 (Pt 9):1133-9.
-
(1997)
J Cell Sci
, vol.110 PART 9
, pp. 1133-1139
-
-
Johansson, M.W.1
Patarroyo, M.2
Oberg, F.3
Siegbahn, A.4
Nilsson, K.5
-
58
-
-
19944429288
-
Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins
-
Lau D, Mollnau H, Eiserich JP etal. Myeloperoxidase mediates neutrophil activation by association with CD11b/CD18 integrins. Proc Natl Acad Sci USA 2005; 102:431-6.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 431-436
-
-
Lau, D.1
Mollnau, H.2
Eiserich, J.P.3
-
59
-
-
0032881201
-
The activation of the neutrophil respiratory burst by anti-neutrophil cytoplasm autoantibody (ANCA) from patients with systemic vasculitis requires tyrosine kinases and protein kinase C activation
-
Radford DJ, Lord JM, Savage COS. The activation of the neutrophil respiratory burst by anti-neutrophil cytoplasm autoantibody (ANCA) from patients with systemic vasculitis requires tyrosine kinases and protein kinase C activation. Clin Exp Immunol 1999; 118:171-9.
-
(1999)
Clin Exp Immunol
, vol.118
, pp. 171-179
-
-
Radford, D.J.1
Lord, J.M.2
Savage, C.O.S.3
-
60
-
-
0035165470
-
Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies
-
Kettritz R, Schreiber A, Luft FC, Haller H. Role of mitogen-activated protein kinases in activation of human neutrophils by antineutrophil cytoplasmic antibodies. J Am Soc Nephrol 2001; 12:37-46.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 37-46
-
-
Kettritz, R.1
Schreiber, A.2
Luft, F.C.3
Haller, H.4
-
61
-
-
0037213448
-
Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA
-
Choi M, Rolle S, Rane M, Haller H, Luft FC, Kettritz R. Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA. Kidney Int 2003; 63:96-106.
-
(2003)
Kidney Int
, vol.63
, pp. 96-106
-
-
Choi, M.1
Rolle, S.2
Rane, M.3
Haller, H.4
Luft, F.C.5
Kettritz, R.6
-
62
-
-
42449162927
-
Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha
-
Polzer K, Soleiman A, Baum W etal. Selective p38MAPK isoform expression and activation in antineutrophil cytoplasmatic antibody-associated crescentic glomerulonephritis: role of p38MAPKalpha. Ann Rheum Dis 2008; 67:602-8.
-
(2008)
Ann Rheum Dis
, vol.67
, pp. 602-608
-
-
Polzer, K.1
Soleiman, A.2
Baum, W.3
-
63
-
-
78751702875
-
Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo
-
van der Veen BS, Chen M, Muller R etal. Effects of p38 mitogen-activated protein kinase inhibition on anti-neutrophil cytoplasmic autoantibody pathogenicity in vitro and in vivo. Ann Rheum Dis 2011; 70:356-65.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 356-365
-
-
van der Veen, B.S.1
Chen, M.2
Muller, R.3
-
64
-
-
0035469819
-
Antineutrophil cytoplasm autoantibodies from patients with systemic vasculitis activate neutrophils through distinct signaling cascades: comparison with conventional Fcgamma receptor ligation
-
Ben-Smith A, Dove SK, Martin A, Wakelam MJ, Savage CO. Antineutrophil cytoplasm autoantibodies from patients with systemic vasculitis activate neutrophils through distinct signaling cascades: comparison with conventional Fcgamma receptor ligation. Blood 2001; 98:1448-55.
-
(2001)
Blood
, vol.98
, pp. 1448-1455
-
-
Ben-Smith, A.1
Dove, S.K.2
Martin, A.3
Wakelam, M.J.4
Savage, C.O.5
-
65
-
-
0036293233
-
Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils
-
Kettritz R, Choi M, Butt W etal. Phosphatidylinositol 3-kinase controls antineutrophil cytoplasmic antibodies-induced respiratory burst in human neutrophils. J Am Soc Nephrol 2002; 13:1740-9.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1740-1749
-
-
Kettritz, R.1
Choi, M.2
Butt, W.3
-
66
-
-
34848894606
-
Febrile temperatures control antineutrophil cytoplasmic autoantibody-induced neutrophil activation via inhibition of phosphatidylinositol 3-kinase/Akt
-
von Vietinghoff S, Choi M, Rolle S, Luft FC, Kettritz R. Febrile temperatures control antineutrophil cytoplasmic autoantibody-induced neutrophil activation via inhibition of phosphatidylinositol 3-kinase/Akt. Arthritis Rheum 2007; 56:3149-58.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 3149-3158
-
-
von Vietinghoff, S.1
Choi, M.2
Rolle, S.3
Luft, F.C.4
Kettritz, R.5
-
67
-
-
33646375699
-
Fever-like temperatures affect neutrophil NF-kappaB signaling, apoptosis, and ANCA-antigen expression
-
Kettritz R, Choi M, Salanova B, Wellner M, Rolle S, Luft FC. Fever-like temperatures affect neutrophil NF-kappaB signaling, apoptosis, and ANCA-antigen expression. J Am Soc Nephrol 2006; 17:1345-53.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1345-1353
-
-
Kettritz, R.1
Choi, M.2
Salanova, B.3
Wellner, M.4
Rolle, S.5
Luft, F.C.6
-
68
-
-
73349137614
-
Phosphoinositol 3-kinase-gamma mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis
-
Schreiber A, Rolle S, Peripelittchenko L etal. Phosphoinositol 3-kinase-gamma mediates antineutrophil cytoplasmic autoantibody-induced glomerulonephritis. Kidney Int 2010; 77:118-28.
-
(2010)
Kidney Int
, vol.77
, pp. 118-128
-
-
Schreiber, A.1
Rolle, S.2
Peripelittchenko, L.3
-
69
-
-
33847052568
-
Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies
-
Xiao H, Schreiber A, Heeringa P, Falk RJ, Jennette JC. Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies. Am J Pathol 2007; 170:52-64.
-
(2007)
Am J Pathol
, vol.170
, pp. 52-64
-
-
Xiao, H.1
Schreiber, A.2
Heeringa, P.3
Falk, R.J.4
Jennette, J.C.5
-
70
-
-
33947651247
-
Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice
-
Huugen D, van Esch A, Xiao H etal. Inhibition of complement factor C5 protects against anti-myeloperoxidase antibody-mediated glomerulonephritis in mice. Kidney Int 2007; 71:646-54.
-
(2007)
Kidney Int
, vol.71
, pp. 646-654
-
-
Huugen, D.1
van Esch, A.2
Xiao, H.3
-
71
-
-
24744448647
-
Modulating autoimmunity: pick your PI3 kinase
-
Ohashi PS, Woodgett JR. Modulating autoimmunity: pick your PI3 kinase. Nat Med 2005; 11:924-5.
-
(2005)
Nat Med
, vol.11
, pp. 924-925
-
-
Ohashi, P.S.1
Woodgett, J.R.2
-
72
-
-
0029801153
-
IL-1 beta production by human polymorphonuclear leucocytes stimulated by anti-neutrophil cytoplasmic autoantibodies: relevance to systemic vasculitis
-
Brooks CJ, King WJ, Radford DJ, Adu D, McGrath M, Savage CO. IL-1 beta production by human polymorphonuclear leucocytes stimulated by anti-neutrophil cytoplasmic autoantibodies: relevance to systemic vasculitis. Clin Exp Immunol 1996; 106:273-9.
-
(1996)
Clin Exp Immunol
, vol.106
, pp. 273-279
-
-
Brooks, C.J.1
King, W.J.2
Radford, D.J.3
Adu, D.4
McGrath, M.5
Savage, C.O.6
-
73
-
-
0032986616
-
Interleukin-8: a pathogenetic role in antineutrophil cytoplasmic autoantibody-associated glomerulonephritis
-
Cockwell P, Brooks CJ, Adu D, Savage COS. Interleukin-8: a pathogenetic role in antineutrophil cytoplasmic autoantibody-associated glomerulonephritis. Kidney Int 1999; 55:852-63.
-
(1999)
Kidney Int
, vol.55
, pp. 852-863
-
-
Cockwell, P.1
Brooks, C.J.2
Adu, D.3
Savage, C.O.S.4
-
74
-
-
67650073210
-
Intracellular cytokine production in ANCA-associated vasculitis: low levels of interleukin-10 in remission are associated with a higher relapse rate in the long-term follow-up
-
Hruskova Z, Rihova Z, Mareckova H etal. Intracellular cytokine production in ANCA-associated vasculitis: low levels of interleukin-10 in remission are associated with a higher relapse rate in the long-term follow-up. Arch Med Res 2009; 40:276-84.
-
(2009)
Arch Med Res
, vol.40
, pp. 276-284
-
-
Hruskova, Z.1
Rihova, Z.2
Mareckova, H.3
-
75
-
-
0027532596
-
In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis
-
Noronha IL, Kruger C, Andrassy K, Ritz E, Waldherr R. In situ production of TNF-alpha, IL-1 beta and IL-2R in ANCA-positive glomerulonephritis. Kidney Int 1993; 43:682-92.
-
(1993)
Kidney Int
, vol.43
, pp. 682-692
-
-
Noronha, I.L.1
Kruger, C.2
Andrassy, K.3
Ritz, E.4
Waldherr, R.5
-
76
-
-
2442637919
-
Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis
-
Timoshanko JR, Kitching AR, Iwakura Y, Holdsworth SR, Tipping PG. Leukocyte-derived interleukin-1beta interacts with renal interleukin-1 receptor I to promote renal tumor necrosis factor and glomerular injury in murine crescentic glomerulonephritis. Am J Pathol 2004; 164:1967-77.
-
(2004)
Am J Pathol
, vol.164
, pp. 1967-1977
-
-
Timoshanko, J.R.1
Kitching, A.R.2
Iwakura, Y.3
Holdsworth, S.R.4
Tipping, P.G.5
-
77
-
-
84863269507
-
Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis
-
Schreiber A, Pham CT, Hu Y, Schneider W, Luft FC, Kettritz R. Neutrophil serine proteases promote IL-1beta generation and injury in necrotizing crescentic glomerulonephritis. J Am Soc Nephrol 2012; 23:470-82.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 470-482
-
-
Schreiber, A.1
Pham, C.T.2
Hu, Y.3
Schneider, W.4
Luft, F.C.5
Kettritz, R.6
-
78
-
-
33646487150
-
Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils
-
Lu X, Garfield A, Rainger GE, Savage CO, Nash GB. Mediation of endothelial cell damage by serine proteases, but not superoxide, released from antineutrophil cytoplasmic antibody-stimulated neutrophils. Arthritis Rheum 2006; 54:1619-28.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 1619-1628
-
-
Lu, X.1
Garfield, A.2
Rainger, G.E.3
Savage, C.O.4
Nash, G.B.5
-
79
-
-
84855586266
-
Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticles
-
Hong Y, Eleftheriou D, Hussain AA etal. Anti-neutrophil cytoplasmic antibodies stimulate release of neutrophil microparticles. J Am Soc Nephrol 2012; 23:49-62.
-
(2012)
J Am Soc Nephrol
, vol.23
, pp. 49-62
-
-
Hong, Y.1
Eleftheriou, D.2
Hussain, A.A.3
-
80
-
-
67349279881
-
Netting neutrophils in autoimmune small-vessel vasculitis
-
Kessenbrock K, Krumbholz M, Schonermarck U etal. Netting neutrophils in autoimmune small-vessel vasculitis. Nat Med 2009; 15:623-5.
-
(2009)
Nat Med
, vol.15
, pp. 623-625
-
-
Kessenbrock, K.1
Krumbholz, M.2
Schonermarck, U.3
|