Lysine demethylase LSD1 coordinates glycolytic and mitochondrial metabolism in hepatocellular carcinoma cells

Cancer Research

Volumn 75, Issue 7, 2015, Pages 1445-1456

  Sakamoto, Akihisa ^a,b   Hino, Shinjiro ^a   Nagaoka, Katsuya ^a   Anan, Kotaro ^a   Takase, Ryuta ^a   Matsumori, Haruka ^a   Ojima, Hidenori ^c   Kanai, Yae ^c   Arita, Kazunori ^b   Nakao, Mitsuyoshi ^a,d  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE TRANSPORTER 1; GLYCOLYTIC ENZYME; HYPOXIA INDUCIBLE FACTOR 1ALPHA; LYSINE SPECIFIC DEMETHYLASE 1; UNCLASSIFIED DRUG; UNCLASSIFIED ENZYME; HIF1A PROTEIN, HUMAN; HISTONE; HISTONE DEMETHYLASE; KDM1A PROTEIN, HUMAN; SLC2A1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER TISSUE; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE ACTIVATION; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORT; GLUT1 GENE; GLYCOLYSIS; HEPATOCELLULAR CARCINOMA CELL LINE; HISTONE DEMETHYLATION; HISTONE METHYLATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPLETION; PROTEIN EXPRESSION; TUMOR ENGRAFTMENT; UPREGULATION; ANIMAL; CANCER TRANSPLANTATION; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HEPG2 CELL LINE; LIVER MITOCHONDRION; LIVER TUMOR; METABOLISM; METHYLATION; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; SCID MOUSE; TUMOR VOLUME;

ANIMALS; CARCINOMA, HEPATOCELLULAR; GENE EXPRESSION; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; HEP G2 CELLS; HISTONE DEMETHYLASES; HISTONES; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LIVER NEOPLASMS; METHYLATION; MICE, SCID; MITOCHONDRIA, LIVER; NEOPLASM TRANSPLANTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; TUMOR BURDEN;

EID: 84942926198     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-14-1560     Document Type: Article

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