Regulation of mitochondrial dynamics by Dynamin- related protein-1 in acute cardiorenal syndrome

Journal of the American Society of Nephrology

Volumn 26, Issue 10, 2015, Pages 2378-2387

  Sumida, Maki ^a   Doi, Kent ^a   Ogasawara, Emi ^a   Yamashita, Tetsushi ^a   Hamasaki, Yoshifumi ^a   Kariya, Taro ^a   Takimoto, Eiki ^a   Yahagi, Naoki ^a   Nangaku, Masaomi ^a   Noiri, Eisei ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b JAPAN INTERNATIONAL COOPERATION AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DYNAMIN; DYNAMIN RELATED PROTEIN 1; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; OPTIC ATROPHY 1; UNCLASSIFIED DRUG; DNM1L PROTEIN, MOUSE;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIORENAL SYNDROME; CELL FRACTIONATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; ELECTRON MICROSCOPY; HEART; HEART DISEASE; HEART MUSCLE CELL; IN VITRO STUDY; IN VIVO STUDY; KIDNEY; KIDNEY ARTERY; KIDNEY ISCHEMIA; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRION; MOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; ACUTE DISEASE; ANIMAL; C57BL MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACUTE DISEASE; ANIMALS; CARDIO-RENAL SYNDROME; DYNAMINS; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIAL DYNAMICS;

EID: 84942890361     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2014080750     Document Type: Article

References (43)

1. Bellomo R, Kellum JA, Ronco C: Acute kidney injury. Lancet 380: 756- 766, 2012.
2. Kellum JA, Bellomo R, Ronco C: Kidney attack. JAMA 307: 2265-2266, 2012.
3. Chawla LS, Amdur RL, Shaw AD, Faselis C, Palant CE, Kimmel PL: Association between AKI and long-term renal and cardiovascular outcomes in United States veterans. Clin J Am Soc Nephrol 9: 448-456, 2014.
4. Ronco C, Haapio M, House AA, Anavekar N, Bellomo R: Cardiorenal syndrome. J AmColl Cardiol 52: 1527-1539, 2008.
5. Rosner MH, Ronco C, Okusa MD: The role of inflammation in the cardiorenal syndrome: A focus on cytokines and inflammatory mediators. Semin Nephrol 32: 70-78, 2012.
6. Bagshaw SM, Hoste EA, Braam B, Briguori C, Kellum JA, McCullough PA, Ronco C: Cardiorenal syndrome type 3: Pathophysiologic and epidemiologic considerations. Contrib Nephrol 182: 137-157, 2013.
7. Mullens W, Abrahams Z, Francis GS, Sokos G, Taylor DO, Starling RC, Young JB, Tang WH: Importance of venous congestion for worsening of renal function in advanced decompensated heart failure. J Am Coll Cardiol 53: 589-596, 2009.
8. Robinson SC, Bowmer CJ, Yates MS: Cardiac function in rats with acute renal failure. J Pharm Pharmacol 44: 1007-1014, 1992.
9. Kelly KJ: Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 14: 1549-1558, 2003.
10. Nath KA, Grande JP, Croatt AJ, Frank E, Caplice NM, Hebbel RP, Katusic ZS: Transgenic sickle mice are markedly sensitive to renal ischemia- reperfusion injury. Am J Pathol 166: 963-972, 2005.
11. Archer SL: Mitochondrial dynamics-mitochondrial fission and fusion in human diseases. N Engl J Med 369: 2236-2251, 2013.
12. Santel A, Fuller MT: Control of mitochondrial morphology by a human mitofusin. J Cell Sci 114: 867-874, 2001.
13. Legros F, Lombès A, Frachon P, Rojo M:Mitochondrial fusion in human cells is efficient, requires the inner membrane potential, and is mediated by mitofusins. Mol Biol Cell 13: 4343-4354, 2002.
14. Alexander C, Votruba M, Pesch UE, Thiselton DL, Mayer S, Moore A, Rodriguez M, Kellner U, Leo-Kottler B, Auburger G, Bhattacharya SS, Wissinger B:OPA1, encoding a dynamin-related GTPase, ismutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat Genet 26: 211-215, 2000.
15. Brooks C, Wei Q, Cho SG, Dong Z: Regulation of mitochondrial dynamics in acute kidney injury in cell culture and rodent models. J Clin Invest 119: 1275-1285, 2009.
16. Ong SB, Subrayan S, Lim SY, Yellon DM, Davidson SM, Hausenloy DJ: Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 121: 2012-2022, 2010.
17. Sharp WW, Fang YH, Han M, Zhang HJ, Hong Z, Banathy A, Morrow E, Ryan JJ, Archer SL: Dynamin-related protein 1 (Drp1)-mediated diastolic dysfunction in myocardial ischemia-reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission. FASEB J 28: 316-326, 2014.
18. Braschi E, McBride HM: Mitochondria and the culture of the Borg: Understanding the integration of mitochondrial function within the reticulum, the cell, and the organism. BioEssays 32: 958-966, 2010.
19. Martinou JC, Youle RJ: Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics. Dev Cell 21: 92-101, 2011.
20. Suen DF, Norris KL, Youle RJ: Mitochondrial dynamics and apoptosis. Genes Dev 22: 1577-1590, 2008.
21. Frank S, Gaume B, Bergmann-Leitner E S, Leitner WW, Robert EG, Catez F, Smith CL, Youle RJ: The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1: 515-525, 2001.
22. Germain M, Mathai JP, McBride HM, Shore GC: Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J 24: 1546-1556, 2005.
23. Ban-Ishihara R, Ishihara T, Sasaki N, Mihara K, Ishihara N: Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c. Proc Natl Acad Sci U S A 110: 11863-11868, 2013.
24. Breckenridge DG, Stojanovic M, Marcellus RC, Shore GC: Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol 160: 1115-1127, 2003.
25. Arnoult D, Rismanchi N, Grodet A, Roberts RG, Seeburg DP, Estaquier J, Sheng M, Blackstone C: Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death. Curr Biol 15: 2112-2118, 2005.
26. Wasiak S, Zunino R, McBride HM: Bax/Bak promote sumoylation of DRP1 and its stable association withmitochondria during apoptotic cell death. J Cell Biol 177: 439-450, 2007.
27. Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P, Lenaers G: Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 278: 7743-7746, 2003.
28. Sugioka R, Shimizu S, Tsujimoto Y: Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis. J Biol Chem 279: 52726-52734, 2004.
29. Taguchi N, Ishihara N, Jofuku A, Oka T, Mihara K: Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission. J Biol Chem 282: 11521-11529, 2007.
30. Park YY, Lee S, Karbowski M, Neutzner A, Youle RJ, Cho H: Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci 123: 619-626, 2010.
31. Cassidy-Stone A, Chipuk JE, Ingerman E, Song C, Yoo C, Kuwana T, Kurth MJ, Shaw JT, Hinshaw JE, Green DR, Nunnari J: Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization. Dev Cell 14: 193-204, 2008.
32. Park SW, Kim KY, Lindsey JD, Dai Y, Heo H, Nguyen DH, Ellisman MH, Weinreb RN, Ju WK: A selective inhibitor of drp1, mdivi-1, increases retinal ganglion cell survival in acute ischemic mouse retina. Invest Ophthalmol Vis Sci 52: 2837-2843, 2011.
33. Zhang N, Wang S, Li Y, Che L, Zhao Q: A selective inhibitor of Drp1, mdivi-1, acts against cerebral ischemia/reperfusion injury via an antiapoptotic pathway in rats. Neurosci Lett 535: 104-109, 2013.
34. Doi K, Ishizu T, Tsukamoto-Sumida M, Hiruma T, Yamashita T, Ogasawara E, Hamasaki Y, Yahagi N, Nangaku M, Noiri E: The highmobility group protein B1-Toll-like receptor 4 pathway contributes to the acute lung injury induced by bilateral nephrectomy. Kidney Int 86: 316-326, 2014.
35. Andrés-Hernando A, Altmann C, Ahuja N, Lanaspa MA, Nemenoff R, He Z, Ishimoto T, Simpson PA, Weiser-Evans MC, Bacalja J, Faubel S: Splenectomy exacerbates lung injury after ischemic acute kidney injury in mice. Am J Physiol Renal Physiol 301: F907-F916, 2011.
36. Awad AS, Rouse M, Huang L, Vergis AL, Reutershan J, Cathro HP, Linden J, Okusa MD: Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney Int 75: 689-698, 2009.
37. Patschan D, Krupincza K, Patschan S, Zhang Z, Hamby C, Goligorsky MS: Dynamics of mobilization and homing of endothelial progenitor cells after acute renal ischemia: Modulation by ischemic preconditioning. Am J Physiol Renal Physiol 291: F176-F185, 2006.
38. U.S. Department of Health and Human Services Public Health Services: NIH Publication No. 86-23. NIH Guide for the Care and Use of Laboratory Animals, National Institutes of Health, Bethesda, MD, 1985.
39. Yamamoto T, Noiri E, Ono Y, Doi K, Negishi K, Kamijo A, Kimura K, Fujita T, Kinukawa T, Taniguchi H, Nakamura K, Goto M, Shinozaki N, Ohshima S, Sugaya T: Renal L-type fatty acid-binding protein in acute ischemic injury. J Am Soc Nephrol 18: 2894-2902, 2007.
40. Yuen PS, Dunn SR, Miyaji T, Yasuda H, Sharma K, Star RA: A simplified method for HPLC determination of creatinine in mouse serum. Am J Physiol Renal Physiol 286: F1116-F1119, 2004.
41. Doi K, Okamoto K, Negishi K, Suzuki Y, Nakao A, Fujita T, Toda A, Yokomizo T, Kita Y, Kihara Y, Ishii S, Shimizu T, Noiri E: Attenuation of folic acid-induced renal inflammatory injury in platelet-activating factor receptor-deficient mice. Am J Pathol 168: 1413-1424, 2006.
42. Takimoto E, Champion HC, LiM, Belardi D, Ren S, Rodriguez ER, Bedja D, Gabrielson KL, Wang Y, Kass DA: Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy. Nat Med 11: 214-222, 2005.
43. Takimoto E, Koitabashi N, Hsu S, Ketner EA, Zhang M, Nagayama T, Bedja D, Gabrielson KL, Blanton R, Siderovski DP, Mendelsohn ME, Kass DA: Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. J Clin Invest 119: 408-420, 2009.