Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury

American Journal of Pathology

Volumn 166, Issue 4, 2005, Pages 963-972

  Nath, Karl A ^a,c   Grande, Joseph P ^a   Croatt, Anthony J ^a   Frank, Elena ^a   Caplice, Noel M ^a   Hebbel, Robert P ^b   Katusic, Zvonimir S ^a  

^a Mayo Clinic   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CASPASE 3; HEMOGLOBIN; SERUM AMYLOID P;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ERYTHROCYTE; HEART INFARCTION PREVENTION; HEART INJURY; HISTOPATHOLOGY; INJURY; KIDNEY ARTERY STENOSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; LUNG INJURY; MICROCIRCULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; SICKLE CELL ANEMIA; TRANSGENIC MOUSE;

EID: 17244380071     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)62318-8     Document Type: Article

References (57)

1. Embury SH, Hebbel RP, Steinberg MH, Mohandas N: Pathogenesis of vasoocclusion. Sickle Cell Disease: Basic Principles and Clinical Practice. Edited by Embury SH, Hebbel RP, Mohandas N, Steinberg MH. New York, Raven, 1994, pp 311-326
2. Kaul DK, Fabry ME, Nagel RL: The pathophysiology of vascular obstruction in the sickle syndromes. Blood Rev 1996, 10:29-44
3. Hebbel RP: Blockade of adhesion of sickle cells to endothelium by monoclonal antibodies. N Engl J Med 2000, 342:1910-1912
4. Osarogiagbon UR, Choong S, Belcher JD, Vercellotti GM, Paller MS, Hebbel RP: Reperfusion injury pathophysiology in sickle transgenic mice. Blood 2000, 96:314-320
5. Cheung AT, Chen PC, Larkin EC, Duong PL, Ramanujam S, Tablin F, Wun T: Microvascular abnormalities in sickle cell disease: a computer-assisted intravital microscopy study. Blood 2002, 99:3999-4005
6. Nath KA, Katusic ZS, Gladwin MT: The perfusion paradox and vascular instability in sickle cell disease. Microcirculation 2004, 11:179-193
7. Zager RA, Baltes LA, Sharma HM, Jurkowitz MS: Responses of the ischemic acute renal failure kidney to additional ischemic events. Kidney Int 1984, 26:689-700
8. Zager RA, Jurkowitz MS, Merola AJ: Responses of the normal rat kidney to sequential ischemic events. Am J Physiol 1985, 249:F148-F149
9. Park KM, Kramers C, Vayssier-Taussat M, Chen A, Bonventre JV: Prevention of kidney ischemia/reperfusion-induced functional injury, MAPK and MAPK kinase activation, and inflammation by remote transient ureteral obstruction. J Biol Chem 2002, 277:2040-2049
10. Bonventre JV: Kidney ischemic preconditioning. Curr Opin Nephrol Hypertens 2002, 11:43-48
11. Gumina RJ, Pucar D, Bast P, Hodgson DM, Kurtz CE, Dzeja PP, Miki T, Seino S, Terzic A: Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics. Am J Physiol 2003, 284:H2106-H2113
12. Eisen A, Fisman EZ, Rubenfire M, Freimark D, McKechnie R, Tenenbaum A, Motro M, Adler Y: Ischemic preconditioning: nearly two decades of research. A comprehensive review. Atherosclerosis 2004, 172:201-210
13. Solomon SD, Anavekar NS, Greaves S, Rouleau JL, Hennekens C, Pfeffer MA, HEART Investigators: Angina pectoris prior to myocardial infarction protects against subsequent left ventricular remodeling. J Am Coll Cardiol 2004, 43:1511-1514
14. Pong K: Ischaemic preconditioning: therapeutic implications for stroke? Expert Opin Ther Targets 2004, 8:125-139
15. Nath KA, Grande JP, Haggard JJ, Croatt AJ, Katusic ZS, Solovey A, Hebbel RP: Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. Am J Pathol 2001, 158:893-903
16. Powars DR, Elliott-Mills DD, Chan L, Niland J, Hiti AL, Opas LM, Johnson C: Chronic renal failure in sickle cell disease: risk factors, clinical course, and mortality. Ann Intern Med 1991, 115:614-620
17. de Jong PE, Statius van Eps LW: Sickle cell nephropathy: new insights into its pathophysiology. Kidney Int 1985, 27:711-717
18. Falk RJ, Jennette JC: Sickle cell nephropathy. Adv Nephrol Necker Hosp 1994, 23:133-147
19. Saborio P, Scheinman JI: Sickle cell nephropathy. J Am Soc Nephrol 1999, 10:187-192
20. Pham PT, Pham PC, Wilkinson AH, Lew SQ: Renal abnormalities in sickle cell disease. Kidney Int 2000, 57:1-8
21. Wesson DE: The initiation and progression of sickle cell nephropathy. Kidney Int 2002, 61:2277-2286
22. Nath KA, Shah V, Haggard JJ, Croatt AJ, Smith LA, Hebbel RP, Katusic ZS: Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease. Am J Physiol 2000, 279:R1949-R1955
23. Fabry ME, Sengupta A, Suzuka SM, Costantini F, Rubin EM, Hofrichter J, Christoph G, Manci E, Culberson D, Factor SM: A second generation transgenic mouse model expressing both hemoglobin S (HbS) and HbS-Antilles results in increased phenotypic severity. Blood 1995, 86:2419-2428
24. Rabb H, Ramirez G, Saba SR, Reynolds D, Xu J, Flavell R, Antonia S: Renal ischemic-reperfusion injury in L-selectin-deficient mice. Am J Physiol 1996, 271:F408-F413
25. Zager RA, Johnson A, Hanson S, dela Rosa V: Altered cholesterol localization and caveolin expression during the evolution of acute renal failure. Kidney Int 2002, 61:1674-1683
26. Nath KA, Haggard JJ, Croatt AJ, Grande JP, Poss KD, Alam J: The indispensability of heme oxygenase-1 in protecting against acute heme protein-induced toxicity in vivo. Am J Pathol 2000, 156:1527-1535
27. Nath KA, Vercellotti GM, Grande JP, Miyoshi H, Paya CV, Manivel JC, Haggard JJ, Croatt AJ, Payne WD, Alam J: Heme protein-induced chronic renal inflammation: suppressive effect of induced heme oxygenase-1. Kidney Int 2001, 59:106-117
28. Belcher JD, Bryant CJ, Nguyen J, Bowlin PR, Kielbik MC, Bischof JC, Hebbel RP, Vercellotti GM: Transgenic sickle mice have vascular inflammation. Blood 2003, 101:3953-3959
29. Kimmelstiel P: Vascular occlusion and ischemic infarction in sickle cell disease. Am J Med Sci 1948, 216:11-19
30. Femi-Pearse D, Odunjo EO: Renal cortical infarcts in sickle-cell trait. Br Med J 1968, 3:34
31. Miller WA, Peck D, Lowman RM: Perirenal hematoma in association with renal infarction in sickle-cell trait. Radiology 1969, 92:351-352
32. Sickles EA, Korobkin M: Perirenal hematoma as a complication of renal infarction in sickle-cell trait. A case report. Am J Roentgenol Radium Ther Nucl Med 1974, 122:800-803
33. al Ani O, Baqi N: Clinical quiz. Cortical infarction secondary to intravascular sickling in the renal cortex. Pediatr Nephrol 1999, 13:267-268
34. Mason J, Welsch J, Torhorst J: The contribution of vascular obstruction to the functional defect that follows renal ischemia. Kidney Int 1987, 31:65-71
35. Olof P, Hellberg A, Kallskog O, Wolgast M: Red cell trapping and postischemic renal blood flow. Differences between the cortex, outer and inner medulla. Kidney Int 1991, 40:625-631
36. Brodsky SV, Yamamoto T, Tada T, Kim B, Chen J, Kajiya F, Goligorsky MS: Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells. Am J Physiol 2002, 282:F1140-F1149
37. Sutton TA, Fisher CJ, Molitoris BA: Microvascular endothelial injury and dysfunction during ischemic acute renal failure. Kidney Int 2002, 62:1539-1549
38. Sutton TA, Mang HE, Campos SB, Sandoval RM, Yoder MC, Molitoris BA: Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol 2003, 285:F191-F198
39. Bohle A, von Gise H, Mackensen-Haen S, Stark-Jakob B: The obliteration of the postglomerular capillaries and its influence upon the function of both glomeruli and tubuli. Functional interpretation of morphologic findings. Klin Wochenschr 1981, 59:1043-1051
40. Nath KA: Tubulointerstitial changes as a major determinant in the progression of renal damage. Am J Kidney Dis 1992, 20:1-17
41. Basile DP, Donohoe D, Roethe K, Osborn JL: Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function. Am J Physiol 2001, 281:F887-F899
42. Basile DP, Donohoe DL, Roethe K, Mattson DL: Chronic renal hypoxia after acute ischemic injury: effects of L-arginine on hypoxia and secondary damage. Am J Physiol 2003, 284:F338-F348
43. Basile DP: Rarefaction of peritubular capillaries following ischemic acute renal failure: a potential factor predisposing to progressive nephropathy. Curr Opin Nephrol Hypertens 2004, 13:1-7
44. Basile DP, Martin DR, Hammerman MR: Extracellular matrix-related genes in kidney after ischemic injury, potential role for TGF-beta in repair. Am J Physiol 1998, 275:F894-F903
45. Sung FL, Zhu TY, Au-Yeung KK, Siow YL, OK: Enhanced MCP-1 expression during ischemia/reperfusion injury is mediated by oxidative stress and NF-kappaB. Kidney Int 2002, 62:1160-1170
46. Kramer AA, Postler G, Salhab KF, Mendez C, Carey LC, Rabb H: Renal ischemia/reperfusion leads to macrophage-mediated increase in pulmonary vascular permeability. Kidney Int 1999, 55:2362-2367
47. Rabb H, Wang Z, Nemoto T, Hotchkiss J, Yokota N, Soleimani M: Acute renal failure leads to dysregulation of lung salt and water channels. Kidney Int 2003, 63:600-606
48. Kelly KJ: Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 2003, 14:1549-1558
49. Kielar ML, Rohan Jeyarajah D, Lu CY: The regulation of ischemic acute renal failure by extrarenal organs. Curr Opin Nephrol Hypertens 2002, 11:451-457
50. Simmons EM, Himmelfarb J, Sezer MT, Chertow GM, Mehta RL, Paganini EP, Soroko S, Freedman S, Becker K, Spratt D, Shyr Y, Ikizler TA, PICARD Study Group: Plasma cytokine levels predict mortality in patients with acute renal failure. Kidney Int 2004, 65:1357-1365
51. Calabro P, Willerson JT, Yen ET: Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Circulation 2003, 108:1930-1932
52. Hattori Y, Matsumura M, Kasai K: Vascular smooth muscle cell activation by C-reactive protein. Cardiovasc Res 2003, 58:186-195
53. Verma S, Yeh ET: C-reactive protein and atherothrombosis-beyond a biomarker: an actual partaker of lesion formation. Am J Physiol 2003, 285:R1253-R1258
54. Yeh ET, Palusinski RP: C-reactive protein: the pawn has been promoted to queen. Curr Atheroscler Rep 2003, 5:101-105
55. Lobo SM, Lobo FR, Bota DP, Lopes-Ferreira F, Soliman HM, Melot C, Vincent JL: C-reactive protein levels correlate with mortality and organ failure in critically ill patients. Chest 2003, 123:2043-2049
56. Bourantas KL, Dalekos GN, Makis A, Chaidos A, Tsiara S, Mavridis A: Acute phase proteins and interleukins in steady state sickle cell disease. Eur J Haematol 1998, 61:49-54
57. Perelman N, Selvaraj SK, Batra S, Luck LR, Erdreich-Epstein A, Coates TD, Kalra VK, Malik P: Placenta growth factor activates monocytes and correlates with sickle cell disease severity. Blood 2003, 102:1506-1514