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Volumn 44, Issue 9, 2015, Pages 714-721

A reverse Warburg metabolism in oral squamous cell carcinoma is not dependent upon myofibroblasts

Author keywords

Myofibroblast; Oral squamous cell carcinoma; Reverse Warburg effect

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CAVEOLIN 1; GLUCOSE TRANSPORTER 1; KI 67 ANTIGEN; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 4; PEPTIDES AND PROTEINS; PROTEIN TOMM20; UNCLASSIFIED DRUG; ACTA2 PROTEIN, HUMAN; ACTIN; COTRANSPORTER; MONOCARBOXYLATE TRANSPORT PROTEIN 1; MONOCARBOXYLATE TRANSPORTER; MUSCLE PROTEIN; SLC16A4 PROTEIN, HUMAN;

EID: 84942885449     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/jop.12297     Document Type: Article
Times cited : (21)

References (31)
  • 1
    • 32144457645 scopus 로고
    • Über den Stoffwechsel der Carcinomzelle
    • Warburg O. Über den Stoffwechsel der Carcinomzelle. Naturwissenschaften 1924; 12: 1131-7.
    • (1924) Naturwissenschaften , vol.12 , pp. 1131-1137
    • Warburg, O.1
  • 2
    • 74849087878 scopus 로고    scopus 로고
    • The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
    • Pavlides S, Whitaker-Menezes D, Castello-Cros R, et al. The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma. Cell Cycle 2009a; 8: 3984-4001.
    • (2009) Cell Cycle , vol.8 , pp. 3984-4001
    • Pavlides, S.1    Whitaker-Menezes, D.2    Castello-Cros, R.3
  • 3
    • 66549114050 scopus 로고    scopus 로고
    • An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers
    • Witkiewicz AK, Dasgupta A, Sotgia F, et al. An absence of stromal caveolin-1 expression predicts early tumor recurrence and poor clinical outcome in human breast cancers. Am J Pathol 2009; 174: 2023-34.
    • (2009) Am J Pathol , vol.174 , pp. 2023-2034
    • Witkiewicz, A.K.1    Dasgupta, A.2    Sotgia, F.3
  • 4
    • 79957922046 scopus 로고    scopus 로고
    • Evidence for a stromal-epithelial 'lactate shuttle' in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts
    • Whitaker-Menezes D, Martinez-Outschoorn UE, Lin Z, et al. Evidence for a stromal-epithelial 'lactate shuttle' in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts. Cell Cycle 2011a; 10: 1772-83.
    • (2011) Cell Cycle , vol.10 , pp. 1772-1783
    • Whitaker-Menezes, D.1    Martinez-Outschoorn, U.E.2    Lin, Z.3
  • 5
    • 79551572428 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer
    • Bello IO, Vered M, Dayan D, et al. Cancer-associated fibroblasts, a parameter of the tumor microenvironment, overcomes carcinoma-associated parameters in the prognosis of patients with mobile tongue cancer. Oral Oncol 2011; 47: 33-8.
    • (2011) Oral Oncol , vol.47 , pp. 33-38
    • Bello, I.O.1    Vered, M.2    Dayan, D.3
  • 6
    • 79551692337 scopus 로고    scopus 로고
    • Stromal features are predictive of disease mortality in oral cancer patients
    • Marsh D, Suchak K, Moutasim KA, et al. Stromal features are predictive of disease mortality in oral cancer patients. J Pathol 2011; 223: 470-81.
    • (2011) J Pathol , vol.223 , pp. 470-481
    • Marsh, D.1    Suchak, K.2    Moutasim, K.A.3
  • 7
    • 71949119461 scopus 로고    scopus 로고
    • Tumor-host histopathologic variables, stromal myofibroblasts and risk score, are significantly associated with recurrent disease in tongue cancer
    • Vered M, Dobriyan A, Dayan D, et al. Tumor-host histopathologic variables, stromal myofibroblasts and risk score, are significantly associated with recurrent disease in tongue cancer. Cancer Sci 2010; 101: 274-80.
    • (2010) Cancer Sci , vol.101 , pp. 274-280
    • Vered, M.1    Dobriyan, A.2    Dayan, D.3
  • 8
    • 80052265882 scopus 로고    scopus 로고
    • Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A
    • Sobral LM, Bufalino A, Lopes MA, et al. Myofibroblasts in the stroma of oral cancer promote tumorigenesis via secretion of activin A. Oral Oncol 2011; 47: 840-6.
    • (2011) Oral Oncol , vol.47 , pp. 840-846
    • Sobral, L.M.1    Bufalino, A.2    Lopes, M.A.3
  • 9
    • 1642334157 scopus 로고    scopus 로고
    • Tumour-derived TGF-[beta]1 modulates myofibroblast differentiation and promotes HGF//SF-dependent invasion of squamous carcinoma cells
    • Lewis MP, Lygoe KA, Nystrom ML, et al. Tumour-derived TGF-[beta]1 modulates myofibroblast differentiation and promotes HGF//SF-dependent invasion of squamous carcinoma cells. Br J Cancer 2004; 90: 822-32.
    • (2004) Br J Cancer , vol.90 , pp. 822-832
    • Lewis, M.P.1    Lygoe, K.A.2    Nystrom, M.L.3
  • 10
    • 0037899253 scopus 로고    scopus 로고
    • Role of tissue stroma in cancer cell invasion
    • De Wever O, Mareel M. Role of tissue stroma in cancer cell invasion. J Pathol 2003; 200: 429-47.
    • (2003) J Pathol , vol.200 , pp. 429-447
    • De Wever, O.1    Mareel, M.2
  • 11
    • 36549084032 scopus 로고    scopus 로고
    • Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis
    • Kellermann MG, Sobral LM, Silva SDD, et al. Myofibroblasts in the stroma of oral squamous cell carcinoma are associated with poor prognosis. Histopathology 2007; 51: 849-53.
    • (2007) Histopathology , vol.51 , pp. 849-853
    • Kellermann, M.G.1    Sobral, L.M.2    Silva, S.D.D.3
  • 12
    • 33344477759 scopus 로고    scopus 로고
    • Pathology and genetics of head and neck tumours
    • IARC
    • Barnes L. Pathology and genetics of head and neck tumours. IARC, 2005.
    • (2005)
    • Barnes, L.1
  • 13
    • 82855182002 scopus 로고    scopus 로고
    • Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue
    • Whitaker-Menezes D, Martinez-Outschoorn UE, Flomenberg N, et al. Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue. Cell Cycle 2011b; 10: 4047.
    • (2011) Cell Cycle , vol.10 , pp. 4047
    • Whitaker-Menezes, D.1    Martinez-Outschoorn, U.E.2    Flomenberg, N.3
  • 14
    • 84884490529 scopus 로고    scopus 로고
    • EMMPRIN promotes angiogenesis, proliferation, invasion and resistance to sunitinib in renal cell carcinoma, and its level predicts patient outcome
    • Sato M, Nakai Y, Nakata W, et al. EMMPRIN promotes angiogenesis, proliferation, invasion and resistance to sunitinib in renal cell carcinoma, and its level predicts patient outcome. PLoS ONE 2013; 8: e74313.
    • (2013) PLoS ONE , vol.8 , pp. e74313
    • Sato, M.1    Nakai, Y.2    Nakata, W.3
  • 15
    • 84868625980 scopus 로고    scopus 로고
    • Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth
    • Guido C, Whitaker-Menezes D, Lin Z, et al. Mitochondrial fission induces glycolytic reprogramming in cancer-associated myofibroblasts, driving stromal lactate production, and early tumor growth. Oncotarget 2012; 3: 798.
    • (2012) Oncotarget , vol.3 , pp. 798
    • Guido, C.1    Whitaker-Menezes, D.2    Lin, Z.3
  • 16
    • 34047248572 scopus 로고    scopus 로고
    • Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer
    • Humar B, Fukuzawa R, Blair V, et al. Destabilized adhesion in the gastric proliferative zone and c-Src kinase activation mark the development of early diffuse gastric cancer. Cancer Res 2007; 67: 2480-9.
    • (2007) Cancer Res , vol.67 , pp. 2480-2489
    • Humar, B.1    Fukuzawa, R.2    Blair, V.3
  • 17
    • 84877307244 scopus 로고    scopus 로고
    • Expression of conventional and novel glucose transporters, GLUT1,-9,-10, and-12, in vascular smooth muscle cells
    • Pyla R, Poulose N, Jun JY, et al. Expression of conventional and novel glucose transporters, GLUT1, -9, -10, and-12, in vascular smooth muscle cells. Am J Physiol Cell Physiol 2013; 304: C574-89.
    • (2013) Am J Physiol Cell Physiol , vol.304 , pp. C574-C589
    • Pyla, R.1    Poulose, N.2    Jun, J.Y.3
  • 18
    • 78650034777 scopus 로고    scopus 로고
    • Towards a knowledge-based human protein atlas
    • Uhlen M, Oksvold P, Fagerberg L, et al. Towards a knowledge-based human protein atlas. Nat Biotechnol 2010; 28: 1248-50.
    • (2010) Nat Biotechnol , vol.28 , pp. 1248-1250
    • Uhlen, M.1    Oksvold, P.2    Fagerberg, L.3
  • 19
    • 0019486524 scopus 로고
    • A novel immunocytochemical model system for specificity and sensitivity screening of antisera against multiple antigens
    • Larsson L-I. A novel immunocytochemical model system for specificity and sensitivity screening of antisera against multiple antigens. J Histochem Cytochem 1981; 29: 408-10.
    • (1981) J Histochem Cytochem , vol.29 , pp. 408-410
    • Larsson, L.-I.1
  • 20
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: the metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324: 1029-33.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 21
    • 34249933120 scopus 로고    scopus 로고
    • Expression of caveolin-1 reduces cellular responses to TGF-β1 through down-regulating the expression of TGF-β type II receptor gene in NIH3T3 fibroblast cells
    • Lee EK, Lee YS, Han I-O, et al. Expression of caveolin-1 reduces cellular responses to TGF-β1 through down-regulating the expression of TGF-β type II receptor gene in NIH3T3 fibroblast cells. Biochem Biophys Res Commun 2007; 359: 385-90.
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 385-390
    • Lee, E.K.1    Lee, Y.S.2    Han, I.-O.3
  • 22
    • 84900462660 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients
    • Zhu J, Wu Y-N, Zhang W, et al. Monocarboxylate transporter 4 facilitates cell proliferation and migration and is associated with poor prognosis in oral squamous cell carcinoma patients. PLoS ONE 2014; 9: e87904.
    • (2014) PLoS ONE , vol.9 , pp. e87904
    • Zhu, J.1    Wu, Y.-N.2    Zhang, W.3
  • 23
    • 84877150506 scopus 로고    scopus 로고
    • Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
    • Curry JM, Tuluc M, Whitaker-Menezes D, et al. Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer. Cell Cycle 2013; 12: 1371.
    • (2013) Cell Cycle , vol.12 , pp. 1371
    • Curry, J.M.1    Tuluc, M.2    Whitaker-Menezes, D.3
  • 24
    • 0015091526 scopus 로고
    • Permeability of the epidermis and the phagocytic activity of keratinocytes: ultrastructural studies with thorotrast as a marker
    • Wolff K, Hönigsmann H. Permeability of the epidermis and the phagocytic activity of keratinocytes: ultrastructural studies with thorotrast as a marker. J Ultrastruct Res 1971; 36: 176-90.
    • (1971) J Ultrastruct Res , vol.36 , pp. 176-190
    • Wolff, K.1    Hönigsmann, H.2
  • 25
    • 0016231084 scopus 로고
    • Penetration of human albumin through the oral mucosa of guinea-pigs immunized to this protein
    • Tolo K. Penetration of human albumin through the oral mucosa of guinea-pigs immunized to this protein. Arch Oral Biol 1974; 19: 259-63.
    • (1974) Arch Oral Biol , vol.19 , pp. 259-263
    • Tolo, K.1
  • 26
    • 79251517382 scopus 로고    scopus 로고
    • Mak TW Regulation of cancer cell metabolism
    • Cairns RA, Harris IS. Mak TW Regulation of cancer cell metabolism. Nat Rev Cancer 2011; 11: 85-95.
    • (2011) Nat Rev Cancer , vol.11 , pp. 85-95
    • Cairns, R.A.1    Harris, I.S.2
  • 27
    • 33646917296 scopus 로고    scopus 로고
    • The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism
    • Ullah MS, DavieS AJ, Halestrap AP. The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism. J Biol Chem 2006; 281: 9030-7.
    • (2006) J Biol Chem , vol.281 , pp. 9030-9037
    • Ullah, M.S.1    DavieS, A.J.2    Halestrap, A.P.3
  • 28
    • 0035432151 scopus 로고    scopus 로고
    • Hypoxia-inducible factor: Achilles' heel of antiangiogenic cancer therapy (Review)
    • Blagosklonny MV. Hypoxia-inducible factor: Achilles' heel of antiangiogenic cancer therapy (Review). Int J Oncol 2001; 19: 257-62.
    • (2001) Int J Oncol , vol.19 , pp. 257-262
    • Blagosklonny, M.V.1
  • 29
    • 0037478437 scopus 로고    scopus 로고
    • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene
    • Pennacchietti S, Michieli P, Galluzzo M, et al. Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene. Cancer Cell 2003; 3: 347-61.
    • (2003) Cancer Cell , vol.3 , pp. 347-361
    • Pennacchietti, S.1    Michieli, P.2    Galluzzo, M.3
  • 30
    • 1642472018 scopus 로고    scopus 로고
    • Antiangiogenic therapy and tumor progression
    • Blagosklonny MV. Antiangiogenic therapy and tumor progression. Cancer Cell 2004; 5: 13-7.
    • (2004) Cancer Cell , vol.5 , pp. 13-17
    • Blagosklonny, M.V.1
  • 31
    • 77951692165 scopus 로고    scopus 로고
    • Molecular mechanisms of resistance to tumour anti-angiogenic strategies
    • Grépin R, Pagès G. Molecular mechanisms of resistance to tumour anti-angiogenic strategies. J Oncol 2010; 2010: 835680.
    • (2010) J Oncol , vol.2010 , pp. 835680
    • Grépin, R.1    Pagès, G.2


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