메뉴 건너뛰기




Volumn 10, Issue 8, 2015, Pages

Metabolomics reveals metabolically healthy and unhealthy obese individuals differ in their response to a caloric challenge

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCARNITINE; ALANINE; ARACHIDONIC ACID; ARGININE; ASPARAGINE; ASPARTIC ACID; BETAINE; CARNITINE; CITRULLINE; CYSTINE; GAMMA LINOLENIC ACID; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; HISTIDINE; INSULIN; ISOLEUCINE; LEUCINE; LINOLEIC ACID; LYSINE; METHIONINE; MYRISTIC ACID; PALMITIC ACID; PHENYLALANINE; PROLINE; SERINE; THREONINE; VALINE; AMINO ACID; CARBOHYDRATE DIET; FATTY ACID;

EID: 84942880726     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134613     Document Type: Article
Times cited : (46)

References (38)
  • 1
    • 84933678058 scopus 로고    scopus 로고
    • The epidemiology of obesity: A big picture
    • Hruby A, Hu F (2014) The Epidemiology of Obesity: A Big Picture. PharmacoEconomics 1-17.
    • (2014) PharmacoEconomics , pp. 1-17
    • Hruby, A.1    Hu, F.2
  • 2
    • 72749100942 scopus 로고    scopus 로고
    • A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome
    • PMID: 19828712
    • van Dijk SJ, Feskens EJ, Bos MB, Hoelen DW, Heijligenberg R, Bromhaar MG, et al. (2009) A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome. Am J Clin Nutr 90(6):1656-64. doi: 10.3945/ajcn 2009.27792 PMID: 19828712
    • (2009) Am J Clin Nutr , vol.90 , Issue.6 , pp. 1656-1664
    • Van Dijk, S.J.1    Feskens, E.J.2    Bos, M.B.3    Hoelen, D.W.4    Heijligenberg, R.5    Bromhaar, M.G.6
  • 3
    • 84900407381 scopus 로고    scopus 로고
    • Hypertriglyceridemia influences the degree of postprandial lipemic response in patients with metabolic syndrome and coronary artery disease: From the cordioprev study
    • PMID: 24802225
    • Alcala-Diaz JF, Delgado-Lista J, Perez-Martinez P, Garcia-Rios A, Marin C, Quintana-Navarro GM, et al. (2014) Hypertriglyceridemia Influences the Degree of Postprandial Lipemic Response in Patients with Metabolic Syndrome and Coronary Artery Disease: From the Cordioprev Study. PLoS ONE 9(5): e96297. doi: 10.1371/journal.pone.0096297 PMID: 24802225
    • (2014) PLoS ONE , vol.9 , Issue.5 , pp. e96297
    • Alcala-Diaz, J.F.1    Delgado-Lista, J.2    Perez-Martinez, P.3    Garcia-Rios, A.4    Marin, C.5    Quintana-Navarro, G.M.6
  • 5
    • 0032742992 scopus 로고    scopus 로고
    • The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus
    • PMID: 10491414
    • Weyer C, Bogardus C, Mott DM, Pratley RE (1999) The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus. J Clin Invest 104(6):787-94. PMID: 10491414
    • (1999) J Clin Invest , vol.104 , Issue.6 , pp. 787-794
    • Weyer, C.1    Bogardus, C.2    Mott, D.M.3    Pratley, R.E.4
  • 6
    • 84901317554 scopus 로고    scopus 로고
    • Metabolomics reveals differences in postprandial responses to breads and fasting metabolic characteristics associated with postprandial insulin demand in postmenopausal women
    • PMID: 24717363
    • Moazzami AA, Shrestha A, Morrison DA, Poutanen K, Mykkänen H (2014) Metabolomics Reveals Differences in Postprandial Responses to Breads and Fasting Metabolic Characteristics Associated with Postprandial Insulin Demand in Postmenopausal Women. J Nutr 144(6):807-14. doi: 10.3945/jn.113 88912 PMID: 24717363
    • (2014) J Nutr , vol.144 , Issue.6 , pp. 807-814
    • Moazzami, A.A.1    Shrestha, A.2    Morrison, D.A.3    Poutanen, K.4    Mykkänen, H.5
  • 7
    • 84906279651 scopus 로고    scopus 로고
    • Metabolically healthy and unhealthy obese- The 2013 stock conference report
    • PMID: 25059108
    • Samocha-Bonet D, Dixit VD, Kahn CR, Leibel RL, Lin X, Nieuwdorp M, et al. (2014) Metabolically healthy and unhealthy obese-the 2013 Stock Conference report. Obesity Reviews 15(9):697-708. doi: 10.1111/obr.12199 PMID: 25059108
    • (2014) Obesity Reviews , vol.15 , Issue.9 , pp. 697-708
    • Samocha-Bonet, D.1    Dixit, V.D.2    Kahn, C.R.3    Leibel, R.L.4    Lin, X.5    Nieuwdorp, M.6
  • 8
    • 84937423157 scopus 로고    scopus 로고
    • Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals
    • PMID: 25411437
    • Badoud F, Perreault M, Zulyniak MA, Mutch DM (2014) Molecular insights into the role of white adipose tissue in metabolically unhealthy normal weight and metabolically healthy obese individuals. FASEB J 29(3):748-58. doi: 10.1096/fj.14-263913 PMID: 25411437
    • (2014) FASEB J , vol.29 , Issue.3 , pp. 748-758
    • Badoud, F.1    Perreault, M.2    Zulyniak, M.A.3    Mutch, D.M.4
  • 9
    • 48749105019 scopus 로고    scopus 로고
    • Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals
    • PMID: 18551117
    • Succurro E, Marini MA, Frontoni S, Hribal ML, Andreozzi F, Lauro R, et al. (2008) Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals. Obesity 16 (8):1881-6. doi: 10.1038/oby.2008.308 PMID: 18551117
    • (2008) Obesity , vol.16 , Issue.8 , pp. 1881-1886
    • Succurro, E.1    Marini, M.A.2    Frontoni, S.3    Hribal, M.L.4    Andreozzi, F.5    Lauro, R.6
  • 10
    • 79953807628 scopus 로고    scopus 로고
    • Effects of a lifestyle intervention in metabolically benign and malign obesity
    • PMID: 21174075
    • Kantartzis K, Machann J, Schick F, Rittig K, Machicao F, Fritsche A, et al. (2011) Effects of a lifestyle intervention in metabolically benign and malign obesity. Diabetologia 54(4):864-8. doi: 10.1007/s00125-010-2006-3 PMID: 21174075
    • (2011) Diabetologia , vol.54 , Issue.4 , pp. 864-868
    • Kantartzis, K.1    Machann, J.2    Schick, F.3    Rittig, K.4    Machicao, F.5    Fritsche, A.6
  • 12
    • 84890898823 scopus 로고    scopus 로고
    • Characterising metabolically healthy obesity in weight-discordant monozygotic twins
    • PMID: 24100782
    • Naukkarinen J, Heinonen S, Hakkarainen A, Lundbom J, Vuolteenaho K, Saarinen L, et al. (2014) Characterising metabolically healthy obesity in weight-discordant monozygotic twins. Diabetologia 57 (1):167-76. doi: 10.1007/s00125-013-3066-y PMID: 24100782
    • (2014) Diabetologia , vol.57 , Issue.1 , pp. 167-176
    • Naukkarinen, J.1    Heinonen, S.2    Hakkarainen, A.3    Lundbom, J.4    Vuolteenaho, K.5    Saarinen, L.6
  • 13
    • 84903692940 scopus 로고    scopus 로고
    • Serum and adipose tissue amino acid homeostasis in the metabolically healthy obese
    • PMID: 24933025
    • Badoud F, Lam KP, DiBattista A, Perreault M, Zulyniak MA, Cattrysse B, et al. (2014) Serum and Adipose Tissue Amino Acid Homeostasis in the Metabolically Healthy Obese. J Proteome Res 13 (7):3455-66. doi: 10.1021/pr500416v PMID: 24933025
    • (2014) J Proteome Res , vol.13 , Issue.7 , pp. 3455-3466
    • Badoud, F.1    Lam, K.P.2    DiBattista, A.3    Perreault, M.4    Zulyniak, M.A.5    Cattrysse, B.6
  • 14
    • 84895771789 scopus 로고    scopus 로고
    • A distinct fatty acid profile underlies the reduced inflammatory state of metabolically healthy obese individuals
    • PMID: 24520395
    • Perreault M, Zulyniak MA, Badoud F, Stephenson S, Badawi A, Buchholz A, et al. (2014) A Distinct Fatty Acid Profile Underlies the Reduced Inflammatory State of Metabolically Healthy Obese Individuals. PLoS One 9(2):e88539. doi: 10.1371/journal.pone.0088539 PMID: 24520395
    • (2014) PLoS One , vol.9 , Issue.2 , pp. e88539
    • Perreault, M.1    Zulyniak, M.A.2    Badoud, F.3    Stephenson, S.4    Badawi, A.5    Buchholz, A.6
  • 15
    • 84859224327 scopus 로고    scopus 로고
    • Measuring adiposity in patients: The utility of body mass index (bmi), percent body fat, and leptin
    • PMID: 22485140
    • Shah NR, Braverman ER (2012) Measuring Adiposity in Patients: The Utility of Body Mass Index (BMI), Percent Body Fat, and Leptin. PLoS One 7(4):e33308. doi: 10.1371/journal.pone.0033308 PMID: 22485140
    • (2012) PLoS One , vol.7 , Issue.4 , pp. e33308
    • Shah, N.R.1    Braverman, E.R.2
  • 16
    • 11244269558 scopus 로고    scopus 로고
    • Can we identify metabolically healthy but obese individuals (MHO)?
    • Karelis A, Brochu M, Rabasa-Lhoret R (2004) Can we identify metabolically healthy but obese individuals (MHO)? Diabetes & Metabolism 30(6):569-72.
    • (2004) Diabetes & Metabolism , vol.30 , Issue.6 , pp. 569-572
    • Karelis, A.1    Brochu, M.2    Rabasa-Lhoret, R.3
  • 17
    • 72749126091 scopus 로고    scopus 로고
    • Effects of a prolonged standardized diet on normalizing the human metabolome
    • PMID: 19864408
    • Winnike JH, Busby MG, Watkins PB, O'Connell TM (2009) Effects of a prolonged standardized diet on normalizing the human metabolome. Am J Clin Nutr 90(6):1496-501. doi: 10.3945/ajcn.2009.28234 PMID: 19864408
    • (2009) Am J Clin Nutr , vol.90 , Issue.6 , pp. 1496-1501
    • Winnike, J.H.1    Busby, M.G.2    Watkins, P.B.3    O'Connell, T.M.4
  • 18
    • 84861790964 scopus 로고    scopus 로고
    • The dynamic range of the human metabolome revealed by challenges
    • PMID: 22426117
    • Krug S, Kastenmüller G, Stückler F, Rist MJ, Skurk T, Sailer M, et al. (2012) The dynamic range of the human metabolome revealed by challenges. FASEB J 26(6):2607-19. doi: 10.1096/fj.11-198093 PMID: 22426117
    • (2012) FASEB J , vol.26 , Issue.6 , pp. 2607-2619
    • Krug, S.1    Kastenmüller, G.2    Stückler, F.3    Rist, M.J.4    Skurk, T.5    Sailer, M.6
  • 19
    • 84857789767 scopus 로고    scopus 로고
    • Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status
    • PMID: 22448156
    • Pellis L, van Erk M, van Ommen B, Bakker GM, Hendriks HJ, Cnubben NP, et al. (2012) Plasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status. Metabolomics 8(2):347-59. PMID: 22448156
    • (2012) Metabolomics , vol.8 , Issue.2 , pp. 347-359
    • Pellis, L.1    Van Erk, M.2    Van Ommen, B.3    Bakker, G.M.4    Hendriks, H.J.5    Cnubben, N.P.6
  • 21
    • 0038671678 scopus 로고    scopus 로고
    • Postprandial kinetics of dietary amino acids are the main determinant of their metabolism after soy or milk protein ingestion in humans
    • PMID: 12730415
    • Bos C, Metges CC, Gaudichon C, Petzke KJ, Pueyo ME, Morens C, et al. (2003) Postprandial Kinetics of Dietary Amino Acids Are the Main Determinant of Their Metabolism after Soy or Milk Protein Ingestion in Humans. J Nutr 133(5):1308-15. PMID: 12730415
    • (2003) J Nutr , vol.133 , Issue.5 , pp. 1308-1315
    • Bos, C.1    Metges, C.C.2    Gaudichon, C.3    Petzke, K.J.4    Pueyo, M.E.5    Morens, C.6
  • 22
    • 84866279808 scopus 로고    scopus 로고
    • The association of cysteine with obesity, inflammatory cytokines and insulin resistance in hispanic children and adolescents
    • PMID: 22984471
    • Elshorbagy AK, Valdivia-Garcia M, Refsum H, Butte N (2012) The Association of Cysteine with Obesity, Inflammatory Cytokines and Insulin Resistance in Hispanic Children and Adolescents. PLoS ONE 7 (9):e44166. doi: 10.1371/journal.pone.0044166 PMID: 22984471
    • (2012) PLoS ONE , vol.7 , Issue.9 , pp. e44166
    • Elshorbagy, A.K.1    Valdivia-Garcia, M.2    Refsum, H.3    Butte, N.4
  • 23
    • 67649723393 scopus 로고    scopus 로고
    • The association of plasma cysteine and ?-glutamyltransferase with bmi and obesity
    • PMID: 19214177
    • Elshorbagy AK, Refsum H, Smith AD, Graham IM (2009) The Association of Plasma Cysteine and ?-Glutamyltransferase With BMI and Obesity. Obesity 17(7):1435-40. doi: 10.1038/oby.2008.671 PMID: 19214177
    • (2009) Obesity , vol.17 , Issue.7 , pp. 1435-1440
    • Elshorbagy, A.K.1    Refsum, H.2    Smith, A.D.3    Graham, I.M.4
  • 24
    • 41549125912 scopus 로고    scopus 로고
    • Global transcript profiles of fat in monozygotic twins discordant for bmi: Pathways behind acquired obesity
    • PMID: 18336063
    • Pietiläinen KH, Naukkarinen J, Rissanen A, Saharinen J, Ellonen P, Keränen H, et al. (2008) Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity. PLoS Medicine 5(3):e51. doi: 10.1371/journal.pmed.0050051 PMID: 18336063
    • (2008) PLoS Medicine , vol.5 , Issue.3 , pp. e51
    • Pietiläinen, K.H.1    Naukkarinen, J.2    Rissanen, A.3    Saharinen, J.4    Ellonen, P.5    Keränen, H.6
  • 25
    • 84878622190 scopus 로고    scopus 로고
    • Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity
    • PMID: 23512805
    • Lackey DE, Lynch CJ, Olson KC, Mostaedi R, Ali M, Smith WH, et al. (2013) Regulation of adipose branched-chain amino acid catabolism enzyme expression and cross-adipose amino acid flux in human obesity. Am J Physiol Endocrinol Metab 304(11):E1175-E87. doi: 10.1152/ajpendo.00630 2012 PMID: 23512805
    • (2013) Am J Physiol Endocrinol Metab , vol.304 , Issue.11 , pp. E1175-E1187
    • Lackey, D.E.1    Lynch, C.J.2    Olson, K.C.3    Mostaedi, R.4    Ali, M.5    Smith, W.H.6
  • 26
    • 84907026878 scopus 로고    scopus 로고
    • Personalized metabolomics for predicting glucose tolerance changes in sedentary women after high-intensity interval training
    • PMID: 25164777
    • Kuehnbaum NL, Gillen JB, Gibala MJ, Britz-McKibbin P (2014) Personalized Metabolomics for Predicting Glucose Tolerance Changes in Sedentary Women After High-Intensity Interval Training. Sci Rep 4:6166. doi: 10.1038/srep06166 PMID: 25164777
    • (2014) Sci Rep , vol.4 , pp. 6166
    • Kuehnbaum, N.L.1    Gillen, J.B.2    Gibala, M.J.3    Britz-McKibbin, P.4
  • 27
    • 84942871972 scopus 로고    scopus 로고
    • A metabolomic profile associated with insulin resistance and conversion to diabetes in the insulin resistance atherosclerosis study
    • Palmer ND, Stevens RD, Antinozzi PA, Anderson A, Bergman RN, Wagenknecht LE, et al. (2014) A Metabolomic Profile Associated with Insulin Resistance and Conversion to Diabetes in the Insulin Resistance Atherosclerosis Study. J Clin Endocrinol Metab 0(0):jc.2014-357.
    • (2014) J Clin Endocrinol Metab , pp. jc2014-jc2357
    • Palmer, N.D.1    Stevens, R.D.2    Antinozzi, P.A.3    Anderson, A.4    Bergman, R.N.5    Wagenknecht, L.E.6
  • 28
    • 84927950033 scopus 로고    scopus 로고
    • Plasma amino acid profiles are associated with insulin, C-peptide and adiponectin levels in type 2 diabetic patients
    • Nakamura H, Jinzu H, Nagao K, Noguchi Y, Shimba N, Miyano H, et al. (2014) Plasma amino acid profiles are associated with insulin, C-peptide and adiponectin levels in type 2 diabetic patients. Nutrition & Diabetes 4(9):e133.
    • (2014) Nutrition & Diabetes , vol.4 , Issue.9 , pp. e133
    • Nakamura, H.1    Jinzu, H.2    Nagao, K.3    Noguchi, Y.4    Shimba, N.5    Miyano, H.6
  • 29
    • 84874412069 scopus 로고    scopus 로고
    • Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults
    • PMID: 23129134
    • Würtz P, Soininen P, Kangas AJ, Rönnemaa T, Lehtimäki T, Kähönen M, et al. (2013) Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults. Diabetes Care 36 (3):648-55. doi: 10.2337/dc12-0895 PMID: 23129134
    • (2013) Diabetes Care , vol.36 , Issue.3 , pp. 648-655
    • Würtz, P.1    Soininen, P.2    Kangas, A.J.3    Rönnemaa, T.4    Lehtimäki, T.5    Kähönen, M.6
  • 30
    • 84874800752 scopus 로고    scopus 로고
    • Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents
    • PMID: 22961720
    • McCormack SE, Shaham O, McCarthy MA, Deik AA, Wang TJ, Gerszten RE, et al. (2013) Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatric Obesity 8(1):52-61. doi: 10.1111/j.2047-6310.2012.00087.x PMID: 22961720
    • (2013) Pediatric Obesity , vol.8 , Issue.1 , pp. 52-61
    • McCormack, S.E.1    Shaham, O.2    McCarthy, M.A.3    Deik, A.A.4    Wang, T.J.5    Gerszten, R.E.6
  • 31
    • 79953737332 scopus 로고    scopus 로고
    • Metabolite profiles and the risk of developing diabetes
    • PMID: 21423183
    • Wang TJ, Larson MG, Vasan RS, Cheng S, Rhee EP, McCabe E, et al. (2011) Metabolite profiles and the risk of developing diabetes. Nat Med 17(4):448-53. doi: 10.1038/nm.2307 PMID: 21423183
    • (2011) Nat Med , vol.17 , Issue.4 , pp. 448-453
    • Wang, T.J.1    Larson, M.G.2    Vasan, R.S.3    Cheng, S.4    Rhee, E.P.5    McCabe, E.6
  • 32
    • 79953329970 scopus 로고    scopus 로고
    • Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans
    • PMID: 21403394
    • Rhee EP, Cheng S, Larson MG, Walford GA, Lewis GD, McCabe E, et al. (2011) Lipid profiling identifies a triacylglycerol signature of insulin resistance and improves diabetes prediction in humans. The J Clin Invest 121(4):1402-11. doi: 10.1172/JCI44442 PMID: 21403394
    • (2011) The J Clin Invest , vol.121 , Issue.4 , pp. 1402-1411
    • Rhee, E.P.1    Cheng, S.2    Larson, M.G.3    Walford, G.A.4    Lewis, G.D.5    McCabe, E.6
  • 33
    • 0031892855 scopus 로고    scopus 로고
    • Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+
    • PMID: 9519739
    • Komatsu M, SharpGW (1998) Palmitate and myristate selectively mimic the effect of glucose in augmenting insulin release in the absence of extracellular Ca2+. Diabetes 47(3):352-7. PMID: 9519739
    • (1998) Diabetes , vol.47 , Issue.3 , pp. 352-357
    • Komatsu, M.1    Sharp, G.W.2
  • 34
    • 84895880028 scopus 로고    scopus 로고
    • Plasma levels of 14: 0, 16:0, 16:1n-7, and 20:3n-6 are positively associated, but 18:0 and 18:2n-6 are inversely associated with markers of inflammation in young healthy adults
    • PMID: 24338596
    • Perreault M, Roke K, Badawi A, Nielsen D, Abdelmagid S, El-Sohemy A, et al. (2014) Plasma Levels of 14:0, 16:0, 16:1n-7, and 20:3n-6 are Positively Associated, but 18:0 and 18:2n-6 are Inversely Associated with Markers of Inflammation in Young Healthy Adults. Lipids 49(3):255-63. doi: 10.1007/s11745-013-3874-3 PMID: 24338596
    • (2014) Lipids , vol.49 , Issue.3 , pp. 255-263
    • Perreault, M.1    Roke, K.2    Badawi, A.3    Nielsen, D.4    Abdelmagid, S.5    El-Sohemy, A.6
  • 35
    • 84879065722 scopus 로고    scopus 로고
    • Ethnic-and sexspecific associations between plasma fatty acids and markers of insulin resistance in healthy young adults
    • Ralston JC, Zulyniak MA, Nielsen DE, Clarke S, Badawi A, El-Sohemy A, et al. (2013) Ethnic-and sexspecific associations between plasma fatty acids and markers of insulin resistance in healthy young adults. Nutr Metab 10(1):42.
    • (2013) Nutr Metab , vol.10 , Issue.1 , pp. 42
    • Ralston, J.C.1    Zulyniak, M.A.2    Nielsen, D.E.3    Clarke, S.4    Badawi, A.5    El-Sohemy, A.6
  • 36
    • 34447264474 scopus 로고    scopus 로고
    • Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: Interpreting the role of linoleic acid
    • PMID: 17616780
    • Hodge AM, English DR, O'Dea K, Sinclair AJ, Makrides M, Gibson RA, et al. (2007) Plasma phospholipid and dietary fatty acids as predictors of type 2 diabetes: interpreting the role of linoleic acid. Am J Clin Nutr 86(1):189-97. PMID: 17616780
    • (2007) Am J Clin Nutr , vol.86 , Issue.1 , pp. 189-197
    • Hodge, A.M.1    English, D.R.2    O'Dea, K.3    Sinclair, A.J.4    Makrides, M.5    Gibson, R.A.6
  • 37
    • 78149273926 scopus 로고    scopus 로고
    • Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: A pilot study in the european prospective investigation into cancer and nutrition (epic)-norfolk cohort
    • PMID: 20861175
    • Patel PS, Sharp SJ, Jansen E, Luben RN, Khaw K-T, Wareham NJ, et al. (2010) Fatty acids measured in plasma and erythrocyte-membrane phospholipids and derived by food-frequency questionnaire and the risk of new-onset type 2 diabetes: a pilot study in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk cohort. Am J Clin Nutr 92(5):1214-22. doi: 10.3945/ajcn.2010.29182 PMID: 20861175
    • (2010) Am J Clin Nutr , vol.92 , Issue.5 , pp. 1214-1222
    • Patel, P.S.1    Sharp, S.J.2    Jansen, E.3    Luben, R.N.4    Khaw, K.-T.5    Wareham, N.J.6
  • 38
    • 82355163487 scopus 로고    scopus 로고
    • Individual differences in apparent energy digestibility are larger than generally recognized
    • PMID: 22106417
    • Heymsfield SB, Pietrobelli A (2011) Individual differences in apparent energy digestibility are larger than generally recognized. Am J Clin Nutr 94(6):1650-1. doi: 10.3945/ajcn.111.026476 PMID: 22106417
    • (2011) Am J Clin Nutr , vol.94 , Issue.6 , pp. 1650-1651
    • Heymsfield, S.B.1    Pietrobelli, A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.