Postprandial kinetics of dietary amino acids are the main determinant of their metabolism after soy or milk protein ingestion in humans

Journal of Nutrition

Volumn 133, Issue 5, 2003, Pages 1308-1315

  Bos, Cécile ^a   Metges, Cornelia C ^b,d   Gaudichon, Claire ^a   Petzke, Klaus J ^b   Pueyo, Maria E ^a   Morens, Céline ^a   Everwand, Julia ^b   Benamouzig, Robert ^c   Tomé, Daniel ^a  

^a INRA Institut National de la Recherche Agronomique   (France)

^b Unit Protein Metabolism   (Germany)

^c AVICENNE HOSPITAL   (France)

^d LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

Amino acids; Dietary protein; GC C IRMS; Humans; Postprandial metabolism

Indexed keywords

AMINO ACID; GLUCAGON; INSULIN; LIVER PROTEIN; MILK PROTEIN; NITROGEN 15; SOYBEAN PROTEIN;

ADULT; AMINO ACID COMPOSITION; AMINO ACID METABOLISM; ARTICLE; CONTROLLED STUDY; DEAMINATION; DIGESTION; FEMALE; GAS CHROMATOGRAPHY; GLUCAGON BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; INSULIN BLOOD LEVEL; KINETICS; MALE; MASS SPECTROMETRY; NORMAL HUMAN; PERIPHERAL CIRCULATION; POSTPRANDIAL STATE; PROTEIN BLOOD LEVEL; PROTEIN INTAKE; PROTEIN SYNTHESIS;

GLYCINE MAX;

EID: 0038671678     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/133.5.1308     Document Type: Article

References (43)

1. 15N]-labeled milk protein nitrogen is influenced by diet composition in humans. J. Nutr. 129: 890-895.
2. 15N-labelled milk nitrogen in human subjects. Br. J. Nutr. 81: 221-226.
3. Mariotti, F., Mahe, S., Luengo, C., Benamouzig, R. & Tomé, D. (2000) Postprandial modulation of dietary and who(e-body nitrogen utilization by carbohydrates in humans. Am. J. Clin. Nutr. 72: 954-962.
4. Lohrke, B., Saggau, E., Schadereit, R., Beyer, M., Bellman, O., Kuhla, S. & Hagemeister, H. (2001) Activation of skeletal muscle protein breakdown following consumption of soyabean protein in pigs. Br. J. Nutr. 85: 447-457.
5. Deutz, N. E., Bruins, M. J. & Soeters, P. B. (1998) Infusion of soy and casein protein meals affects interorgan amino acid metabolism and urea kinetics differently in pigs. J. Nutr. 128: 2435-2445.
6. 15N]-soy protein isolate assessed from ileal digestibility and postprandial protein utilization in humans. J. Nutr. 129: 1992-1997.
7. Gaudichon, C., Bos, C., Morens, C., Petzke, K. J., Mariotti F., Everwand, J., Benamouzig, R., Dare, S., Tomé, D. & Metges, C. C. (2002) Ileal losses of nitrogen and amino acids in humans and their importance to the assessment of amino acid requirements. Gastroenterology 123: 50-59.
8. Reeds, P. J., Burrin, D. G., Stoll, B. & van Goudoever, J. B. (2000) Role of the gut in the amino acid economy of the host. Nestlé Nutr. Workshop Ser. Clin. Perform. Programme 3: 25-40.
9. Stoll, B., Henry, J., Reeds, P. J., Yu, H., Jahoor, F. & Burrin, D. G. (1998) Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets. J. Nutr. 128: 606-614.
10. Benevenga, N. J., Gahl, M. J. & Blemings, K. P. (1993) Role of protein synthesis in amino acid catabolism. J. Nutr. 123: 332-336.
11. Waterlow, J. C. (1999) The mysteries of nitrogen balance. Nutr. Res. Rev. 12: 25-54.
12. Boirie, Y., Dangin, M., Gachon, P., Vasson, M. P., Maubois, J. L. & Beaufrere, B. (1997) Slow and fast dietary proteins differently modulate postprandial protein accretion. Proc. Natl. Acad. Sci. U.S.A. 94: 14930-14935.
13. Fouillet, H., Mariotti, F., Gaudichon, C., Bos, C. & Tomé, D. (2002) Peripheral and splanchnic metabolism of dietary nitrogen are differently affected by the protein source in humans as assessed by compartmental modeling. J. Nutr. 132: 125-133.
14. Billeaud, C., Guillet, J. & Sandler, B. (1990) Gastric emptying in infants with or without gastro-oesophageal reflux according to the type of milk. Eur. J. Clin. Nutr. 44: 577-583.
15. 15N]beta-lactoglobulin and casein in humans: the influence of the nature and quantity of the protein. Am. J. Clin. Nutr. 63: 546-552.
16. Mahe, S., Huneau, J. F., Marteau, P., Thuillier, F. & Tomé, D. (1992) Gastroileal nitrogen and electrolyte movements after bovine milk ingestion in humans. Am. J. Clin. Nutr. 56: 410-416.
17. Baglieri, A., Mahe, S., Zidi, S., Huneau, J. F., Thuillier, F., Marteau, P. & Tomé, D. (1994) Gastro-jejunal digestion of soya-bean-milk protein in humans. Br. J. Nutr. 72: 519-532.
18. Wilson, R. H. & Leibholz, J. (1981) Digestion in the pig between 7 and 35 d of age. 2. The digestion of dry matter and the pH of digesta in pigs given milk and soya-bean proteins. Br. J. Nutr. 45: 321-336.
19. Moughan, P. J., Cranwell, P. D. & Smith, W. C. (1991) An evaluation with piglets of bovine milk, hydrolyzed bovine milk, and isolated soybean proteins included in infant milk formulas. II. Stomach-emptying rate and the postprandial change in gastric pH and milk-clotting enzyme activity. J. Pediatr. Gastroenterol. Nutr. 12: 253-259.
20. Hara, H., Nishikawa, H. & Kiriyama, S. (1992) Different effects of casein and soyabean protein on gastric emptying of protein and small intestinal transit after spontaneous feeding of diets in rats. Br. J. Nutr. 68: 59-66.
21. Nuttall, F. Q. & Gannon, M. C. (1990) Metabolic response to egg white and cottage cheese protein in normal subjects. Metabolism 39: 749-755.
22. van Loon, L. J., Saris, W. H., Verhagen, H. & Wagenmakers, A. J. (2000) Plasma insulin responses after ingestion of different amino acid or protein mixtures with carbohydrate. Am. J. Clin. Nutr. 72: 96-105.
23. Calbet, J. A. & MacLean, D. A. (2002) Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans. J. Nutr. 132: 2174-2182.
24. De Feo, P., Horber, F. F. & Haymond, M. W. (1992) Meal stimulation of albumin synthesis: a significant contributor to whole body protein synthesis in humans. Am. J. Physiol. 263: E794-E799.
25. Gannon, M. C., Nuttall, F. Q., Neil, B. J. & Westphal, S. A. (1988) The insulin and glucose responses to meals of glucose plus various proteins in type II diabetic subjects. Metabolism 37: 1081-1088.
26. Lang, V., Bellisle, F., Oppert, J. M., Craplet, C., Bornet, F. R., Slama, G. & Guy-Grand, B. (1998) Satiating effect of proteins in healthy subjects: a comparison of egg albumin, casein, gelatin, soy protein, pea protein, and wheat gluten. Am. J. Clin. Nutr. 67: 1197-1204.
27. 14N isotopic composition in individual plasma free amino acids of human adults at natural abundance by gas chromatography-combustion isotope ratio mass spectrometry. Anal. Biochem. 247: 158-164.
28. Metges, C. C. & Petzke, K. J. (1999) The use of GC-C-IRMS for the analysis of stable isotopes in nitrogenous compounds. In: Methods for Investigation of Amino Acid and Protein Metabolism (El-Khoury, A. E., ed.), pp. 121-134. CRC Press, Boca Raton, FL.
29. Gannong, W. F. (1969) Review of Medical Physiology, 4th ed. Lange Medical Publications, Los Altos, CA.
30. Roubenoff, R. (1996) Applications of bioelectrical impedance analysis for body composition to epidemiologic studies. Am. J. Clin. Nutr. 64: 459S-462S.
31. McIntyre, A., Vincent, R. M., Perkins, A. C. & Spiller, R. C. (1997) Effect of bran, ispaghula, and inert plastic particles on gastric emptying and small bowel transit in humans: the role of physical factors. Gut 40: 223-227.
32. Read, N. W., Cammack, J., Edwards, C., Holgate, A. M., Cann, P. A. & Brown, C. (1982) Is the transit time of a meal through the small intestine related to the rate at which it leaves the stomach? Gut 23: 824-828.
33. Patten, G. S., Head, R. J., Abeywardena, M. Y. & McMurchie, E. J. (2001) An apparatus to assay opioid activity in the infused lumen of the intact isolated guinea pig ileum. J. Pharmacol. Toxicol. Methods 45: 39-46.
34. Allescher, H. D., Storr, M., Piller, C., Brantl, V. & Schusdziarra, V. (2000) Effect of opioid active therapeutics on the ascending reflex pathway in the rat ileum. Neuropeptides 34: 181-186.
35. Collin-Vidal, C., Cayol, M., Obled, C., Ziegler, F., Bommelaer, G. & Beaufrere, B. (1994) Leucine kinetics are different during feeding with whole protein or oligopeptides. Am. J. Physiol. 267: E907-E914.
36. Dangin, M., Boirie, Y., Garcia-Rodenas, C., Gachon, P., Fauquant, J., Callier, P., Ballevre, O. & Beaufrere, B. (2001) The digestion rate of protein is an independent regulating factor of postprandial protein retention. Am. J. Physiol. 280:E340-E348.
37. Daenzer, M., Petzke, K. J., Bequette, B. J. & Metges, C. C. (2001) Whole-body nitrogen and splanchnic amino acid metabolism differ in rats fed mixed diets containing casein or its corresponding amino acid mixture. J. Nutr. 131: 1965-1972.
38. Morens, C., Gaudichon, C., Fromentin, G., Marsset-Baglieri, A., Bensaid, A., Larue-Achagiotis, C., Luengo, C. & Tomé, D. (2001) Daily delivery of dietary nitrogen to the periphery is stable in rats adapted to increased protein intake. Am. J. Physiol. 281: E826-E836.
39. Nissen, S. & Haymond, M. W. (1986) Changes in leucine kinetics during meal absorption: effects of dietary leucine availability. Am. J. Physiol. 250: E695-E701.
40. Lecavalier, L., De Feo, P. & Haymond, M. W. (1991) Isolated hypo-isoleucinemia impairs whole body but not hepatic protein synthesis in humans. Am. J. Physiol. 261: E578-E586.
41. Boirie, Y., Gachon, P., Cordat, N., Ritz, P. & Beaufrere, B. (2001) Differential insulin sensitivities of glucose, amino acid, and albumin metabolism in elderly men and women. J. Clin. Endocrinol. Metab. 86: 638-644.
42. Hutton, J. C., Sener, A. & Malaisse, W. J. (1980) Interaction of branched chain amino acids and keto acids upon pancreatic islet metabolism and insulin secretion. J. Biol. Chem. 255: 7340-7346.
43. Sener, A., Blachier, F., Rasschaert, J., Mourtada, A., Malaisse-Lagae, F. & Malaisse, W. J. (1989) Stimulus-secretion coupling of arginine-induced insulin release: comparison with lysine-induced insulin secretion. Endocrinology 124: 2558-2567.