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Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 20, 2015, Pages 4544-4548

Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure-activity relationship and unique pyrrolylation of primary amines

(13) Dasari, Ramesh a Masi, Marco b Lisy, Romana c Ferdérin, Marlène c English, Lance R a Cimmino, Alessio b Mathieu, Véronique c Brenner, Andrew J d Kuhn, John G d Whitten, Steven T a Evidente, Antonio b Kiss, Robert c Kornienko, Alexander a

a Texas State University (United States)

b UNIVERSITY OF NAPLES FEDERICO II (Italy)

c UNIVERSITÉ LIBRE DE BRUXELLES (Belgium)

d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO (United States)

Author keywords

1 4 Dicarbonyl; Paal Knorr; Paraptosis; Pyrrole

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; CYTOTOXIC AGENT; LYSINE; OPHIOBOLIN A; UNCLASSIFIED DRUG; SESTERTERPENE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL LINE; CELL DEATH; CONTROLLED STUDY; DERIVATIZATION; GLIOBLASTOMA; GLIOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; MELANOMA; METABOLITE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION; ANIMAL; BRAIN NEOPLASMS; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

AMINES; ANIMALS; ANTINEOPLASTIC AGENTS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; GLIOBLASTOMA; HUMANS; MICE; MOLECULAR STRUCTURE; SESTERTERPENES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84942825350 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2015.08.066 Document Type: Article

Times cited : (36)

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