Comparison of the efficiency of different NF membranes for the enrichment of milk oligosaccharides from bovine milk

European Food Research and Technology

Volumn 241, Issue 6, 2015, Pages 803-815

  Altmann, Karina ^a   Wutkowski, Adam ^a   Kämpfer, Sebastian ^b   Klempt, Martin ^a   Lorenzen, Peter Chr ^a   Clawin Rädecker, Ingrid ^a  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

^b Central Production and Engineering Müller Service GmbH   (Germany)

Author keywords

Content of MOS in relation to total sugar content; Enrichment of bovine milk oligosaccharides (MOS) by nanofiltration (NF); Immunostimulatory effect; NF B activity; Retention of MOS; Transfer of NF process from laboratory to industrial scale

Indexed keywords

ION EXCHANGE; MAMMALS; MASS SPECTROMETRY; NANOFILTRATION; PILOT PLANTS; SUGARS;

BOVINE MILK; IMMUNOSTIMULATORY EFFECT; INDUSTRIAL SCALE; RETENTION OF MOS; TOTAL SUGARS;

OLIGOSACCHARIDES;

EID: 84942821458     PISSN: 14382377     EISSN: 14382385     Source Type: Journal    
DOI: 10.1007/s00217-015-2505-z     Document Type: Article

References (32)

1. ten Bruggencate SJM, Bovee-Oudenhoven IMJ, Feitsma AL, van Hoffen E, Schoterman MHC (2014) Functional role and mechanisms of sialyllactose and other sialylated milk oligosaccharides. Nutr Rev 72:377–389
2. Mehra R, Kelly P (2006) Milk oligosaccharides: structural and technological aspects. Int Dairy J 16:1334–1340
3. Kunz C, Rudloff S (2006) Health promoting aspects of milk oligosaccharides. Int Dairy J 16:1341–1346
4. Oliveira DL, Wilbey RA, Grandison AS, Duarte LC, Roseiro LB (2012) Separation of oligosaccharides from caprine milk whey, prior to prebiotic evaluation. Int Dairy J 24:102–106
5. Ninonuevo MR, Park Y, Yin H, Zhang J, Ward RE, Clowers BH, German JB, Freeman SL, Killeen K, Grimm R, Lebrilla CB (2006) A strategy for annotating the human milk glycome. J Agric Food Chem 54:7471–7480
6. Boehm G, Stahl B (2007) Oligosaccharides from milk. J Nutr 137:847S–849S
7. Mehra R, Barile D, Marotta M, Lebrilla CB, Chu C, German JB (2014) Novel high-molecular weight fucosylated milk oligosaccharides identified in dairy streams. Plos One. doi:10.1371/journal.pone.0096040
8. Gnoth MJ, Rudloff S, Kunz C, Kinne RKH (2001) Investigations of the in vitro transport of human milk oligosaccharides by a Caco-2 monolayer using a novel high performance liquid chromatography-mass spectrometry technique. J Biol Chem 276:34363–34370
9. Eiwegger T, Stahl B, Schmitt J, Boehm G, Gerstmayr M, Pichler J, Dehlink E, Loibichler C, Urbanek R, Szepfalusi Z (2004) Human milk-derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro. Pediatr Res 56:536–540
10. Lane JA, O’Callaghan J, Carrington SD, Hickey RM (2013) Transcriptional response of HT-29 intestinal epithelial cells to human and bovine milk oligosaccharides. Br J Nutr 110:2127–2137
11. Kurakevich E, Hennet T, Hausmann M, Rogler G, Borsig L (2013) Milk oligosaccharide sialyl(alpha2,3)lactose activates intestinal CD11c+ cells through TLR4. Proc Natl Acad Sci USA 110:17444–17449
12. Rijnierse A, Jeurink PV, van Esch BCAM, Garssen J, Knippels LMJ (2011) Food-derived oligosaccharides exhibit pharmaceutical properties. European Journal of Pharmacology 668(Supplement 1):S117–S123
13. Comstock SS, Wang M, Hester SN, Li M, Donovan SM (2014) Select human milk oligosaccharides directly modulate peripheral blood mononuclear cells isolated from 10-d-old pigs. Br J Nutr 111:819–828
14. Mills S, Ross RP, Hill C, Fitzgerald GF, Stanton C (2011) Milk intelligence: mining milk for bioactive substances associated with human health. Int Dairy J 21:377–401
15. Capitán-Cañadas F, Ortega-González M, Guadix E, Zarzuelo A, Suárez MD, de Medina FS, Martínez-Augustin O (2014) Prebiotic oligosaccharides directly modulate proinflammatory cytokine production in monocytes via activation of TLR4. Mol Nutr Food Res 58:1098–1110
16. Gopal PK, Gill HS (2000) Oligosaccharides and glycoconjugates in bovine milk and colostrum. Br J Nutr 84:69–74
17. Zivkovic AM, Barile D (2011) Bovine milk as a source of functional oligosaccharides for improving human health. Adv Nutr 2:284–289
18. Martinez-Ferez A, Guadix A, Guadix EM (2006) Recovery of caprine milk oligosaccharides with ceramic membranes. J Membr Sci 276:23–30
19. Sarney DB, Hale C, Frankel G, Vulfson EN (2000) A novel approach to the recovery of biologically active oligosaccharides from milk using a combination of enzymatic treatment and nanofiltration. Biotechnol Bioeng 69:461–467
20. Oliveira D, Wilbey RA, Grandison A, Roseiro L (2014) Natural caprine whey oligosaccharides separated by membrane technology and profile evaluation by capillary electrophoresis. Food Bioprocess Technol 7:915–920
21. Packer N, Lawson M, Jardine D, Redmond J (1998) A general approach to desalting oligosaccharides released from glycoproteins. Glycoconj J 15:737–747
22. Bruggink C, Maurer R, Herrmann H, Cavalli S, Hoefler F (2005) Analysis of carbohydrates by anion exchange chromatography and mass spectrometry. J Chromatogr A 1085:104–109
23. Frenzel M, Zerge K, Clawin-Rädecker I, Lorenzen PC (2015) Comparison of the galacto-oligosaccharide forming activity of different β-galactosidases. LWT Food Sci Technol 60:1068–1071
24. Zerge K (2014) Charakterisierung und Gewinnung von Oligosacchariden als potenielle funktionelle Lebensmittelinhaltsstoffe. Doctoral Thesis, Technical University Dresden, Dresden, Germany
25. Malinowski J, Klempt M, Clawin-Rädecker I, Lorenzen PC, Meisel H (2014) Identification of a NFκB inhibitory peptide from tryptic β-casein hydrolysate. Food Chem 165:129–133
26. Fong B, Ma K, McJarrow P (2011) Quantification of bovine milk oligosaccharides using liquid chromatography–selected reaction monitoring–mass spectrometry. J Agric Food Chem 59:9788–9795
27. Luo J, Nordvang RT, Morthensen ST, Zeuner B, Meyer AS, Mikkelsen JD, Pinelo M (2014) An integrated membrane system for the biocatalytic production of 3′-sialyllactose from dairy by-products. Bioresour Technol 166:9–16
28. Schlimme E, Buchheim W (1999) Milch und ihre Inhaltstoffe. Chemische und Physikalische Eigenschaften. Th. Mann, Gelsenkirchen
29. Mariño K, Lane JA, Abrahams JL, Struwe WB, Harvey DJ, Marotta M, Hickey RM, Rudd PM (2011) Method for milk oligosaccharide profiling by 2-aminobenzamide labeling and hydrophilic interaction chromatography. Glycobiology 21:1317–1330
30. Albrecht S, Lane AL, Mariño K, Al Busadah KA, Carrington SD, Hickey RM, Rudd PM (2014) A comparative study of free oligosaccharides in the milk of domestic animals. Br J Nutr 111:1313–1328
31. Urashima T, Fujita S, Fukuda K, Nakamura T, Saito T, Cowan P, Messer M (2014) Chemical characterization of milk oligosaccharides of the common brushtail possum (Trichosurus vulpecula). Glycoconj J 31:387–399
32. Ortega-González M, Ocón B, Romero-Calvo I, Anzola A, Guadix E, Zarzuelo A, Suárez MD, Sánchez de Medina F, Martínez-Augustin O (2014) Nondigestible oligosaccharides exert nonprebiotic effects on intestinal epithelial cells enhancing the immune response via activation of TLR4-NFκB. Mol Nutr Food Res 58:384–393