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Volumn 82, Issue 14, 2008, Pages 7078-7088

The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; INTERLEUKIN 7 RECEPTOR; STEM CELL FACTOR;

EID: 47049083749     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00619-08     Document Type: Article
Times cited : (113)

References (57)
  • 1
    • 0032850736 scopus 로고    scopus 로고
    • The severity of Murray Valley encephalitis in mice is linked to neutrophil infiltration and inducible nitric oxide synthase activity in the central nervous system
    • Andrews, D. M., V. B. Matthews, L. M. Sammels, A. C. Carrello, and P. C. McMinn. 1999. The severity of Murray Valley encephalitis in mice is linked to neutrophil infiltration and inducible nitric oxide synthase activity in the central nervous system. J. Virol. 73:8781-8790.
    • (1999) J. Virol , vol.73 , pp. 8781-8790
    • Andrews, D.M.1    Matthews, V.B.2    Sammels, L.M.3    Carrello, A.C.4    McMinn, P.C.5
  • 2
    • 25444448498 scopus 로고    scopus 로고
    • Cutting edge: TLR2-mediated proinflammatory cytokine and chemokine production hy microglial cells in response to herpes simplex virus
    • Aravalli, R. N., S. Hu, T. N. Rowen, J. M. Palmquist, and J. R. Lokensgard. 2005. Cutting edge: TLR2-mediated proinflammatory cytokine and chemokine production hy microglial cells in response to herpes simplex virus. J. Immunol. 175:4189-4193.
    • (2005) J. Immunol , vol.175 , pp. 4189-4193
    • Aravalli, R.N.1    Hu, S.2    Rowen, T.N.3    Palmquist, J.M.4    Lokensgard, J.R.5
  • 3
    • 14744302017 scopus 로고    scopus 로고
    • Herpes simplex virus infections of the newborn
    • Bale, J. F., and L. J. Miner. 2005. Herpes simplex virus infections of the newborn. Curr. Treat. Options Neurol. 7:151-156.
    • (2005) Curr. Treat. Options Neurol , vol.7 , pp. 151-156
    • Bale, J.F.1    Miner, L.J.2
  • 4
    • 0029037526 scopus 로고
    • Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1
    • Cantin, E. M., D. R. Hinton, J. Chen, and H. Openshaw. 1995. Gamma interferon expression during acute and latent nervous system infection by herpes simplex virus type 1. J. Virol. 69:4898-4905.
    • (1995) J. Virol , vol.69 , pp. 4898-4905
    • Cantin, E.M.1    Hinton, D.R.2    Chen, J.3    Openshaw, H.4
  • 5
    • 33845414503 scopus 로고    scopus 로고
    • Efficient reactivation of latent herpes simplex virus from mouse central nervous system tissues
    • Chen, S.H., H.-W. Yao, W.-Y. Huang, K.-S. Hsu, H.-Y. Lei, A.-L. Shiau, and S.-H. Chen. 2006. Efficient reactivation of latent herpes simplex virus from mouse central nervous system tissues. J. Virol. 80:12387-12392.
    • (2006) J. Virol , vol.80 , pp. 12387-12392
    • Chen, S.H.1    Yao, H.-W.2    Huang, W.-Y.3    Hsu, K.-S.4    Lei, H.-Y.5    Shiau, A.-L.6    Chen, S.-H.7
  • 7
    • 0027272534 scopus 로고
    • Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family
    • Fleming, T. J., M. L. Fleming, and T. R. Malek. 1993. Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family. J. Immunol. 151:2399-2408.
    • (1993) J. Immunol , vol.151 , pp. 2399-2408
    • Fleming, T.J.1    Fleming, M.L.2    Malek, T.R.3
  • 8
    • 0029002659 scopus 로고
    • Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared
    • Ford, A. L., A. L. Goodsall, W. F. Hickey, and J. D. Sedgwick. 1995. Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared. J. Immunol. 154:4309-4321.
    • (1995) J. Immunol , vol.154 , pp. 4309-4321
    • Ford, A.L.1    Goodsall, A.L.2    Hickey, W.F.3    Sedgwick, J.D.4
  • 9
    • 0035471754 scopus 로고    scopus 로고
    • Interleukin-7: Master regulator of peripheral T-cell homeostasis?
    • Fry, T. J., and C. L. Mackall. 2001. Interleukin-7: master regulator of peripheral T-cell homeostasis? Trends Immunol. 22:564-571.
    • (2001) Trends Immunol , vol.22 , pp. 564-571
    • Fry, T.J.1    Mackall, C.L.2
  • 10
    • 27944446952 scopus 로고    scopus 로고
    • Origins of peripheral B cells in IL-7 receptor-deficient mice
    • Hesslein, D. G. T., S. Y. Yang, and D. G. Schatz. 2006. Origins of peripheral B cells in IL-7 receptor-deficient mice. Mol. Immunol. 43:326-334.
    • (2006) Mol. Immunol , vol.43 , pp. 326-334
    • Hesslein, D.G.T.1    Yang, S.Y.2    Schatz, D.G.3
  • 11
    • 0037378907 scopus 로고    scopus 로고
    • Depletion of neutrophils in IL-10-/- mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter
    • Ismail, H. F., P. Fick, J. Zhang, R. G. Lynch, and D. J. Berg. 2003. Depletion of neutrophils in IL-10-/- mice delays clearance of gastric Helicobacter infection and decreases the Th1 immune response to Helicobacter. J. Immunol. 170:3782-3789.
    • (2003) J. Immunol , vol.170 , pp. 3782-3789
    • Ismail, H.F.1    Fick, P.2    Zhang, J.3    Lynch, R.G.4    Berg, D.J.5
  • 13
    • 0033523613 scopus 로고    scopus 로고
    • Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes
    • Kang, J., M. Coles, and D. H. Raulet. 1999. Defective development of gamma/delta T cells in interleukin 7 receptor-deficient mice is due to impaired expression of T cell receptor gamma genes. J. Exp. Med. 190:973-982.
    • (1999) J. Exp. Med , vol.190 , pp. 973-982
    • Kang, J.1    Coles, M.2    Raulet, D.H.3
  • 14
    • 0030723360 scopus 로고    scopus 로고
    • The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis
    • Krakowski, M. L., and T. Owens. 1997. The central nervous system environment controls effector CD4+ T cell cytokine profile in experimental allergic encephalomyelitis. Eur. J. Immunol. 27:2840-2847.
    • (1997) Eur. J. Immunol , vol.27 , pp. 2840-2847
    • Krakowski, M.L.1    Owens, T.2
  • 15
    • 0036165433 scopus 로고    scopus 로고
    • Immunity to intracellular pathogens as a complex genetic trait
    • Kramnik, I., and V. Boyartchuk. 2002. Immunity to intracellular pathogens as a complex genetic trait. Curr. Opin. Microbiol. 5:111-117.
    • (2002) Curr. Opin. Microbiol , vol.5 , pp. 111-117
    • Kramnik, I.1    Boyartchuk, V.2
  • 16
    • 14044271514 scopus 로고    scopus 로고
    • Development and migration of protective CD8+ T cells into the nervous system following ocular herpes simplex virus-1 infection
    • Lang, A., and J. Nikolich-Zugich. 2005. Development and migration of protective CD8+ T cells into the nervous system following ocular herpes simplex virus-1 infection. J. Immunol. 174:2919-2925.
    • (2005) J. Immunol , vol.174 , pp. 2919-2925
    • Lang, A.1    Nikolich-Zugich, J.2
  • 18
    • 0034118465 scopus 로고    scopus 로고
    • Immunocytochemical characterization of long-term persistent immune activation in human brain after herpes simplex encephalitis
    • Lellouch-Tubiana, A., M. Fohlen, O. Robain, and F. Rozenberg. 2000. Immunocytochemical characterization of long-term persistent immune activation in human brain after herpes simplex encephalitis. Neuropathol. Appl. Neurobiol. 26:285-294.
    • (2000) Neuropathol. Appl. Neurobiol , vol.26 , pp. 285-294
    • Lellouch-Tubiana, A.1    Fohlen, M.2    Robain, O.3    Rozenberg, F.4
  • 19
    • 0036891401 scopus 로고    scopus 로고
    • Glial cell responses to herpesvirus infections: Role in defense and immunopathogenesis
    • Lokensgard, J. R., M. C. Cheeran, S. Hu, G. Gekker, and P. K. Peterson. 2002. Glial cell responses to herpesvirus infections: role in defense and immunopathogenesis. J. Infect. Dis. 186(Suppl. 2):S171-S179.
    • (2002) J. Infect. Dis , vol.186 , Issue.SUPPL. 2
    • Lokensgard, J.R.1    Cheeran, M.C.2    Hu, S.3    Gekker, G.4    Peterson, P.K.5
  • 20
    • 0034922931 scopus 로고    scopus 로고
    • Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus
    • Lokensgard, J. R., S. Hu, W. Sheng, M. vanOijen, D. Cox, M. C. Cheeran, and P. K. Peterson. 2001. Robust expression of TNF-alpha, IL-1beta, RANTES, and IP-10 by human microglial cells during nonproductive infection with herpes simplex virus. J. Neurovirol. 7:208-219.
    • (2001) J. Neurovirol , vol.7 , pp. 208-219
    • Lokensgard, J.R.1    Hu, S.2    Sheng, W.3    vanOijen, M.4    Cox, D.5    Cheeran, M.C.6    Peterson, P.K.7
  • 21
    • 0016850988 scopus 로고
    • Genetics of natural resistance to herpesvirus infections in mice
    • Lopez, C. 1975. Genetics of natural resistance to herpesvirus infections in mice. Nature 258:152-153.
    • (1975) Nature , vol.258 , pp. 152-153
    • Lopez, C.1
  • 22
    • 0019739413 scopus 로고
    • Resistance to herpes simplex virus - type 1 (HSV-1)
    • Lopez, C. 1981. Resistance to herpes simplex virus - type 1 (HSV-1). Curr. Top. Microbiol. Immunol. 92:15-24.
    • (1981) Curr. Top. Microbiol. Immunol , vol.92 , pp. 15-24
    • Lopez, C.1
  • 23
    • 0019291938 scopus 로고
    • Resistance to HSV-1 in the mouse is governed by two major, independently segregating, non-H-2 loci
    • Lopez, C. 1980. Resistance to HSV-1 in the mouse is governed by two major, independently segregating, non-H-2 loci. Immunogenetics 11:87-92.
    • (1980) Immunogenetics , vol.11 , pp. 87-92
    • Lopez, C.1
  • 24
    • 35148834159 scopus 로고    scopus 로고
    • Effects of CXCR3 signaling on development of fatal encephalitis and corneal and periocular skin disease in HSV-infected mice are mouse-strain dependent
    • Lundberg, P., H. Openshaw, M. Wang, H. J. Yang, and E. Cantin. 2007. Effects of CXCR3 signaling on development of fatal encephalitis and corneal and periocular skin disease in HSV-infected mice are mouse-strain dependent. Investig. Ophthalmol. Vis. Sci. 48:4162-4170.
    • (2007) Investig. Ophthalmol. Vis. Sci , vol.48 , pp. 4162-4170
    • Lundberg, P.1    Openshaw, H.2    Wang, M.3    Yang, H.J.4    Cantin, E.5
  • 25
    • 0142124128 scopus 로고    scopus 로고
    • A locus on mouse chromosome 6 that determines resistance to herpes simplex virus also influences reactivation, while an unlinked locus augments resistance of female mice
    • Lundberg, P., P. Welander, H. Openshaw, C. Nalbandian, C. Edwards, L. Moldawer, and E. Cantin. 2003. A locus on mouse chromosome 6 that determines resistance to herpes simplex virus also influences reactivation, while an unlinked locus augments resistance of female mice. J. Virol. 77:11661-11673.
    • (2003) J. Virol , vol.77 , pp. 11661-11673
    • Lundberg, P.1    Welander, P.2    Openshaw, H.3    Nalbandian, C.4    Edwards, C.5    Moldawer, L.6    Cantin, E.7
  • 26
    • 33846476600 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2
    • Lundberg, P., P. V. Welander, C. K. Edwards III, N. van Rooijen, and E. Cantin. 2007. Tumor necrosis factor (TNF) protects resistant C57BL/6 mice against herpes simplex virus-induced encephalitis independently of signaling via TNF receptor 1 or 2. J. Virol. 81:1451-1460.
    • (2007) J. Virol , vol.81 , pp. 1451-1460
    • Lundberg, P.1    Welander, P.V.2    Edwards III, C.K.3    van Rooijen, N.4    Cantin, E.5
  • 27
    • 0026635179 scopus 로고
    • Pathways of viral gene expression during acute neuronal infection with HSV-1
    • Margolis, T. P., F. Sedarati, A. T. Dobson, L. T. Feldman, and J. G. Stevens. 1992. Pathways of viral gene expression during acute neuronal infection with HSV-1. Virology 189:150-160.
    • (1992) Virology , vol.189 , pp. 150-160
    • Margolis, T.P.1    Sedarati, F.2    Dobson, A.T.3    Feldman, L.T.4    Stevens, J.G.5
  • 29
    • 0037300921 scopus 로고    scopus 로고
    • Experimental herpes simplex virus encephalitis: A combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities
    • Meyding-Lamade, U. K., C. Oberlinner, P. R. Rau, S. Seyfer, S. Heiland, J. Sellner, B. T. Wildemann, and W. R. Lamade. 2003. Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities. J. Neurovirol. 9:118-125.
    • (2003) J. Neurovirol , vol.9 , pp. 118-125
    • Meyding-Lamade, U.K.1    Oberlinner, C.2    Rau, P.R.3    Seyfer, S.4    Heiland, S.5    Sellner, J.6    Wildemann, B.T.7    Lamade, W.R.8
  • 31
    • 0031058875 scopus 로고    scopus 로고
    • Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo
    • Miller, C. L., V. I. Rebel, C. D. Helgason, P. M. Lansdorp, and C. J. Eaves. 1997. Impaired steel factor responsiveness differentially affects the detection and long-term maintenance of fetal liver hematopoietic stem cells in vivo. Blood 89:1214-1223.
    • (1997) Blood , vol.89 , pp. 1214-1223
    • Miller, C.L.1    Rebel, V.I.2    Helgason, C.D.3    Lansdorp, P.M.4    Eaves, C.J.5
  • 33
    • 0026758280 scopus 로고
    • Predominance of Th1 cells in ocular tissues during herpetic stromal keratitis
    • Niemialtowski, M. G., and B. T. Rouse. 1992. Predominance of Th1 cells in ocular tissues during herpetic stromal keratitis. J. Immunol. 149:3035-3039.
    • (1992) J. Immunol , vol.149 , pp. 3035-3039
    • Niemialtowski, M.G.1    Rouse, B.T.2
  • 34
    • 0025334596 scopus 로고
    • Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W
    • Nocka, K., J. C. Tan, E. Chiu, T. Y. Chu, P. Ray, P. Traktman, and P. Besmer. 1990. Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J. 9:1805-1813.
    • (1990) EMBO J , vol.9 , pp. 1805-1813
    • Nocka, K.1    Tan, J.C.2    Chiu, E.3    Chu, T.Y.4    Ray, P.5    Traktman, P.6    Besmer, P.7
  • 35
  • 36
    • 33947168235 scopus 로고    scopus 로고
    • Herpes simplex virus infections in preterm infants
    • O'Riordan, D. P., W. C. Golden, and S. W. Aucott. 2006. Herpes simplex virus infections in preterm infants. Pediatrics 118:e1612-e1620.
    • (2006) Pediatrics , vol.118
    • O'Riordan, D.P.1    Golden, W.C.2    Aucott, S.W.3
  • 38
    • 0025218634 scopus 로고
    • W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor
    • Reith, A. D., R. Rottapel, E. Giddens, C. Brady, L. Forrester, and A. Bernstein. 1990. W mutant mice with mild or severe developmental defects contain distinct point mutations in the kinase domain of the c-kit receptor. Genes Dev. 4:390-400.
    • (1990) Genes Dev , vol.4 , pp. 390-400
    • Reith, A.D.1    Rottapel, R.2    Giddens, E.3    Brady, C.4    Forrester, L.5    Bernstein, A.6
  • 39
    • 0023504742 scopus 로고
    • An inquiry into the mechanisms of herpes simplex virus latency
    • Roizman, B., and A. E. Sears. 1987. An inquiry into the mechanisms of herpes simplex virus latency. Annu. Rev. Microbiol. 41:543-577.
    • (1987) Annu. Rev. Microbiol , vol.41 , pp. 543-577
    • Roizman, B.1    Sears, A.E.2
  • 40
    • 0032721294 scopus 로고    scopus 로고
    • Encephalitis
    • Roos, K. L. 1999. Encephalitis. Neurol. Clin. 17:813-833.
    • (1999) Neurol. Clin , vol.17 , pp. 813-833
    • Roos, K.L.1
  • 41
    • 0041823868 scopus 로고    scopus 로고
    • Genetic susceptibility to infectious disease
    • Segal, S., and A. V. Hill. 2003. Genetic susceptibility to infectious disease. Trends Microbiol. 11:445-448.
    • (2003) Trends Microbiol , vol.11 , pp. 445-448
    • Segal, S.1    Hill, A.V.2
  • 42
    • 33847687292 scopus 로고    scopus 로고
    • Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice
    • Sergerie, Y., G. Boivin, D. Gosselin, and S. Rivest. 2007. Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice. J. Infect. Dis. 195:817-825.
    • (2007) J. Infect. Dis , vol.195 , pp. 817-825
    • Sergerie, Y.1    Boivin, G.2    Gosselin, D.3    Rivest, S.4
  • 43
    • 34548490485 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and interleukin 1-beta play a critical role in the resistance against lethal herpes simplex virus encephalitis
    • Sergerie, Y., S. Rivest, and G. Boivin. 2007. Tumor necrosis factor-alpha and interleukin 1-beta play a critical role in the resistance against lethal herpes simplex virus encephalitis. J. Infect. Dis. 196:853-860.
    • (2007) J. Infect. Dis , vol.196 , pp. 853-860
    • Sergerie, Y.1    Rivest, S.2    Boivin, G.3
  • 44
    • 0035026471 scopus 로고    scopus 로고
    • Tracking the spread of a lacZ-tagged herpes simplex virus type 1 between the eye and the nervous system of the mouse: Comparison of primary and recurrent infection
    • Shimeld, C., S. Efstathiou, and T. Hill. 2001. Tracking the spread of a lacZ-tagged herpes simplex virus type 1 between the eye and the nervous system of the mouse: comparison of primary and recurrent infection. J. Virol. 75:5252-5262.
    • (2001) J. Virol , vol.75 , pp. 5252-5262
    • Shimeld, C.1    Efstathiou, S.2    Hill, T.3
  • 46
    • 0031066764 scopus 로고    scopus 로고
    • On the essential involvement of neutrophils in the immunopathologic disease: Herpetic stromal keratitis
    • Thomas, J., S. Gangappa, S. Kanangat, and B. T. Rouse. 1997. On the essential involvement of neutrophils in the immunopathologic disease: herpetic stromal keratitis. J. Immunol. 158:1383-1391.
    • (1997) J. Immunol , vol.158 , pp. 1383-1391
    • Thomas, J.1    Gangappa, S.2    Kanangat, S.3    Rouse, B.T.4
  • 47
    • 0034104642 scopus 로고    scopus 로고
    • Herpes simplex replication and dissemination is not increased by corticosteroid treatment in a rat model of focal Herpes encephalitis
    • Thompson, K. A., W. W. Blessing, and S. L. Wesselingh. 2000. Herpes simplex replication and dissemination is not increased by corticosteroid treatment in a rat model of focal Herpes encephalitis. J. Neurovirol. 6:25-32.
    • (2000) J. Neurovirol , vol.6 , pp. 25-32
    • Thompson, K.A.1    Blessing, W.W.2    Wesselingh, S.L.3
  • 48
    • 0030045764 scopus 로고    scopus 로고
    • Neutrophilmediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea
    • Tumpey, T. M., S. H. Chen, J. E. Oakes, and R. N. Lausch. 1996. Neutrophilmediated suppression of virus replication after herpes simplex virus type 1 infection of the murine cornea. J. Virol. 70:898-904.
    • (1996) J. Virol , vol.70 , pp. 898-904
    • Tumpey, T.M.1    Chen, S.H.2    Oakes, J.E.3    Lausch, R.N.4
  • 49
    • 0034528620 scopus 로고    scopus 로고
    • Herpes simplex virus type 1 latency in the murine nervous system is associated with oxidative damage to neurons
    • Valyi-Nagy, T., S. J. Olson, K. Valyi-Nagy, T. J. Montine, and T. S. Dermody. 2000. Herpes simplex virus type 1 latency in the murine nervous system is associated with oxidative damage to neurons. Virology 278:309-321.
    • (2000) Virology , vol.278 , pp. 309-321
    • Valyi-Nagy, T.1    Olson, S.J.2    Valyi-Nagy, K.3    Montine, T.J.4    Dermody, T.S.5
  • 50
    • 0347364689 scopus 로고    scopus 로고
    • Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation
    • van Lint, A., M. Ayers, A. G. Brooks, R. M. Coles, W. R. Heath, and F. R. Carbone. 2004. Herpes simplex virus-specific CD8+ T cells can clear established lytic infections from skin and nerves and can partially limit the early spread of virus after cutaneous inoculation. J. Immunol. 172:392-397.
    • (2004) J. Immunol , vol.172 , pp. 392-397
    • van Lint, A.1    Ayers, M.2    Brooks, A.G.3    Coles, R.M.4    Heath, W.R.5    Carbone, F.R.6
  • 51
    • 0028111256 scopus 로고
    • Liposome mediated depletion of macrophages: Mechanism of action, preparation of liposomes and applications
    • Van Roorjen, N., and A. Sanders. 1994. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 174:83-93.
    • (1994) J. Immunol. Methods , vol.174 , pp. 83-93
    • Van Roorjen, N.1    Sanders, A.2
  • 52
    • 20744440453 scopus 로고    scopus 로고
    • Innate STAT1-dependent genomic response of neurons to the antiviral cytokine alpha interferon
    • Wang, J., and I. L. Campbell. 2005. Innate STAT1-dependent genomic response of neurons to the antiviral cytokine alpha interferon. J. Virol. 79:8295-8302.
    • (2005) J. Virol , vol.79 , pp. 8295-8302
    • Wang, J.1    Campbell, I.L.2
  • 53
    • 0036753694 scopus 로고    scopus 로고
    • Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis
    • Waskow, C., S. Paul, C. Haller, M. Gassmann, and H. Rodewald. 2002. Viable c-Kit(W/W) mutants reveal pivotal role for c-kit in the maintenance of lymphopoiesis. Immunity 17:277-288.
    • (2002) Immunity , vol.17 , pp. 277-288
    • Waskow, C.1    Paul, S.2    Haller, C.3    Gassmann, M.4    Rodewald, H.5
  • 55
    • 0037045572 scopus 로고    scopus 로고
    • Viral encephalitis: Familiar infections and emerging pathogens
    • Whitley, R. J., and J. W. Gnann. 2002. Viral encephalitis: familiar infections and emerging pathogens. Lancet 359:507-513.
    • (2002) Lancet , vol.359 , pp. 507-513
    • Whitley, R.J.1    Gnann, J.W.2
  • 57
    • 0346035761 scopus 로고    scopus 로고
    • Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis
    • Zhou, J., S. A. Stohlman, D. R. Hinton, and N. W. Marten. 2003. Neutrophils promote mononuclear cell infiltration during viral-induced encephalitis. J. Immunol. 170:3331-3336.
    • (2003) J. Immunol , vol.170 , pp. 3331-3336
    • Zhou, J.1    Stohlman, S.A.2    Hinton, D.R.3    Marten, N.W.4


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