메뉴 건너뛰기




Volumn 18, Issue 4, 2015, Pages 334-338

Genetic and metabolic determinants of human epigenetic variation

Author keywords

DNMT; Epigenetics; Genotype; Imprinting; Nutrition; TET

Indexed keywords

ALCOHOL CONSUMPTION; DIET; DNA METHYLATION; DNA SEQUENCE; ENVIRONMENTAL FACTOR; EPIGENETICS; GENETIC VARIABILITY; GENOME IMPRINTING; HERITABILITY; HUMAN; NUTRITION; REVIEW; SMOKING; SOCIAL STATUS; FEEDING BEHAVIOR; GENETIC EPIGENESIS; GENETIC VARIATION; GENETICS; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN GENOME; INFERTILITY; MOTOR ACTIVITY; NUTRITIONAL STATUS; SOCIAL BEHAVIOR;

EID: 84942807956     PISSN: 13631950     EISSN: 14736519     Source Type: Journal    
DOI: 10.1097/MCO.0000000000000194     Document Type: Review
Times cited : (21)

References (57)
  • 1
    • 84913562415 scopus 로고    scopus 로고
    • Life course epigenetics and healthy ageing
    • In: Kuh D, Cooper R, Hardy R, Richards M, Ben-Shlomo Y, editors. 1st ed London: Oxford University Press
    • Haggarty P, Ferguson-Smith AC. Life course epigenetics and healthy ageing. In: Kuh D, Cooper R, Hardy R, Richards M, Ben-Shlomo Y, editors. A life course approach to healthy ageing, 1st ed London: Oxford University Press; 2014. pp. 198-212.
    • (2014) A Life Course Approach to Healthy Ageing , pp. 198-212
    • Haggarty, P.1    Ferguson-Smith, A.C.2
  • 2
    • 77957859197 scopus 로고    scopus 로고
    • DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome
    • Ollikainen M, Smith KR, Joo EJ, et al. DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome. Hum Mol Genet 2010; 19: 4176-4188.
    • (2010) Hum Mol Genet , vol.19 , pp. 4176-4188
    • Ollikainen, M.1    Smith, K.R.2    Joo, E.J.3
  • 3
    • 80053449066 scopus 로고    scopus 로고
    • Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins
    • Coolen MW, Statham AL, Qu W, et al. Impact of the genome on the epigenome is manifested in DNA methylation patterns of imprinted regions in monozygotic and dizygotic twins. PLoS One 2011; 6: E25590.
    • (2011) PLoS One , vol.6 , pp. e25590
    • Coolen, M.W.1    Statham, A.L.2    Qu, W.3
  • 4
    • 79959997358 scopus 로고    scopus 로고
    • Epigenetic discordance at imprinting control regions in twins
    • Ollikainen M, Craig JM. Epigenetic discordance at imprinting control regions in twins. Epigenomics 2011; 3: 295-306.
    • (2011) Epigenomics , vol.3 , pp. 295-306
    • Ollikainen, M.1    Craig, J.M.2
  • 5
    • 84878004354 scopus 로고    scopus 로고
    • Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance
    • Martino D, Loke YJ, Gordon L, et al. Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance. Genome Biol 2013; 14: R42.
    • (2013) Genome Biol , vol.14 , pp. R42
    • Martino, D.1    Loke, Y.J.2    Gordon, L.3
  • 6
    • 84922067700 scopus 로고    scopus 로고
    • Genome-wide DNA methylation variability in adolescent monozygotic twins followed since birth
    • Levesque ML, Casey KF, Szyf M, et al. Genome-wide DNA methylation variability in adolescent monozygotic twins followed since birth. Epigenetics 2014; 9: 1410-1421.
    • (2014) Epigenetics , vol.9 , pp. 1410-1421
    • Levesque, M.L.1    Casey, K.F.2    Szyf, M.3
  • 7
    • 84861797256 scopus 로고    scopus 로고
    • Nutrition and the epigenome
    • Haggarty P. Nutrition and the epigenome. Prog Mol Biol Translat Sci 2012; 108: 427-466.
    • (2012) Prog Mol Biol Translat Sci , vol.108 , pp. 427-466
    • Haggarty, P.1
  • 8
  • 9
    • 83855163995 scopus 로고    scopus 로고
    • Uncovering the role of 5-hydroxymethylcytosine in the epigenome
    • Branco MR, Ficz G, Reik W. Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nat Rev Genet 2012; 13: 7-13.
    • (2012) Nat Rev Genet , vol.13 , pp. 7-13
    • Branco, M.R.1    Ficz, G.2    Reik, W.3
  • 10
    • 84925511390 scopus 로고    scopus 로고
    • Structural insight into autoinhibition and histone H3- induced activation of DNMT3A
    • Guo X, Wang L, Li J, et al. Structural insight into autoinhibition and histone H3- induced activation of DNMT3A. Nature 2015; 517: 640-644.
    • (2015) Nature , vol.517 , pp. 640-644
    • Guo, X.1    Wang, L.2    Li, J.3
  • 11
    • 84939205466 scopus 로고    scopus 로고
    • Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements
    • Zhang W, Spector TD, Deloukas P, et al. Predicting genome-wide DNA methylation using methylation marks, genomic position, and DNA regulatory elements. Genome Biol 2015; 16: 14.
    • (2015) Genome Biol , vol.16 , pp. 14
    • Zhang, W.1    Spector, T.D.2    Deloukas, P.3
  • 12
    • 76249083210 scopus 로고    scopus 로고
    • ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain
    • Kernohan KD, Jiang Y, Tremblay DC, et al. ATRX partners with cohesin and MeCP2 and contributes to developmental silencing of imprinted genes in the brain. Dev Cell 2010; 18: 191-202.
    • (2010) Dev Cell , vol.18 , pp. 191-202
    • Kernohan, K.D.1    Jiang, Y.2    Tremblay, D.C.3
  • 13
    • 78549247463 scopus 로고    scopus 로고
    • L1 retrotransposition in neurons is modulated by MeCP2
    • Muotri AR, Marchetto MC, Coufal NG, et al. L1 retrotransposition in neurons is modulated by MeCP2. Nature 2010; 468: 443-446.
    • (2010) Nature , vol.468 , pp. 443-446
    • Muotri, A.R.1    Marchetto, M.C.2    Coufal, N.G.3
  • 14
    • 67549119096 scopus 로고    scopus 로고
    • CTCF: Master weaver of the genome
    • Phillips JE, Corces VG. CTCF: Master weaver of the genome. Cell 2009; 137: 1194-1211.
    • (2009) Cell , vol.137 , pp. 1194-1211
    • Phillips, J.E.1    Corces, V.G.2
  • 15
    • 45849127657 scopus 로고    scopus 로고
    • Intra-individual change over time in DNA methylation with familial clustering
    • Bjornsson HT, Sigurdsson MI, Fallin MD, et al. Intra-individual change over time in DNA methylation with familial clustering. J Am Med Assoc 2008; 299: 2877-2883.
    • (2008) J Am Med Assoc , vol.299 , pp. 2877-2883
    • Bjornsson, H.T.1    Sigurdsson, M.I.2    Fallin, M.D.3
  • 16
    • 80054994283 scopus 로고    scopus 로고
    • Identification of genetic elements that autonomously determine DNA methylation states
    • Lienert F, Wirbelauer C, Som I, et al. Identification of genetic elements that autonomously determine DNA methylation states. Nat Genet 2011; 43: 1091-1097.
    • (2011) Nat Genet , vol.43 , pp. 1091-1097
    • Lienert, F.1    Wirbelauer, C.2    Som, I.3
  • 17
    • 84887322043 scopus 로고    scopus 로고
    • Identification of genetic variants that affect histone modifications in human cells
    • McVicker G, van de Geijn B, Degner JF, et al. Identification of genetic variants that affect histone modifications in human cells. Science 2013; 342: 747-749.
    • (2013) Science , vol.342 , pp. 747-749
    • McVicker, G.1    Van De Geijn, B.2    Degner, J.F.3
  • 18
    • 84887320563 scopus 로고    scopus 로고
    • Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription
    • Kilpinen H, Waszak SM, Gschwind AR, et al. Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. Science 2013; 342: 744-747.
    • (2013) Science , vol.342 , pp. 744-747
    • Kilpinen, H.1    Waszak, S.M.2    Gschwind, A.R.3
  • 19
    • 84922621952 scopus 로고    scopus 로고
    • Function and information content of DNA methylation
    • Schubeler D. Function and information content of DNA methylation. Nature 2015; 517: 321-326.
    • (2015) Nature , vol.517 , pp. 321-326
    • Schubeler, D.1
  • 20
    • 84880776373 scopus 로고    scopus 로고
    • DNA methyltransferase candidate polymorphisms, imprinting methylation, and birth outcome
    • Haggarty P, Hoad G, Horgan GW, Campbell DM. DNA methyltransferase candidate polymorphisms, imprinting methylation, and birth outcome. PLoS One 2013; 8: E68896.
    • (2013) PLoS One , vol.8 , pp. e68896
    • Haggarty, P.1    Hoad, G.2    Horgan, G.W.3    Campbell, D.M.4
  • 21
    • 77956224313 scopus 로고    scopus 로고
    • Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking
    • Haggarty P, Hoad G, Harris SE, et al. Human intelligence and polymorphisms in the DNA methyltransferase genes involved in epigenetic marking. PLoS One 2010; 5: E11329.
    • (2010) PLoS One , vol.5 , pp. e11329
    • Haggarty, P.1    Hoad, G.2    Harris, S.E.3
  • 22
    • 78751567821 scopus 로고    scopus 로고
    • Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: Diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer
    • de VS, Wouters KA, Gottschalk RW, et al. Dietary methyl donors, methyl metabolizing enzymes, and epigenetic regulators: Diet-gene interactions and promoter CpG island hypermethylation in colorectal cancer. Cancer Causes Control 2011; 22: 1-12.
    • (2011) Cancer Causes Control , vol.22 , pp. 1-12
    • De, V.S.1    Wouters, K.A.2    Gottschalk, R.W.3
  • 23
    • 84897951905 scopus 로고    scopus 로고
    • Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer
    • Lin J, Zeng RM, Li RN, Cao WH. Aberrant DNA methylation of the P16, MGMT, and hMLH1 genes in combination with the methylenetetrahydrofolate reductase C677T genetic polymorphism and folate intake in gastric cancer. Genet Mol Res 2014; 13: 2060-2068.
    • (2014) Genet Mol Res , vol.13 , pp. 2060-2068
    • Lin, J.1    Zeng, R.M.2    Li, R.N.3    Cao, W.H.4
  • 24
    • 84889795506 scopus 로고    scopus 로고
    • Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson's disease in Chinese Han population
    • Liao XX, Zhan ZX, Luo YY, et al. Association study between SNP rs150689919 in the DNA demethylation gene, TET1, and Parkinson's disease in Chinese Han population. BMC Neurol 2013; 13: 196.
    • (2013) BMC Neurol , vol.13 , pp. 196
    • Liao, X.X.1    Zhan, Z.X.2    Luo, Y.Y.3
  • 25
    • 84883498536 scopus 로고    scopus 로고
    • Methylation loss at H19 imprinted gene correlates with methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples from infertile males
    • Rotondo JC, Selvatici R, Di DM, et al. Methylation loss at H19 imprinted gene correlates with methylenetetrahydrofolate reductase gene promoter hypermethylation in semen samples from infertile males. Epigenetics 2013; 8: 990-997.
    • (2013) Epigenetics , vol.8 , pp. 990-997
    • Rotondo, J.C.1    Selvatici R Di, D.M.2
  • 26
    • 84859150673 scopus 로고    scopus 로고
    • Genetic and nongenetic influences during pregnancy on infant global and site specific DNA methylation: Role for folate gene variants and vitamin B12
    • McKay JA, Groom A, Potter C, et al. Genetic and nongenetic influences during pregnancy on infant global and site specific DNA methylation: Role for folate gene variants and vitamin B12. PLoS One 2012; 7: E33290.
    • (2012) PLoS One , vol.7 , pp. e33290
    • McKay, J.A.1    Groom, A.2    Potter, C.3
  • 27
    • 84871943160 scopus 로고    scopus 로고
    • Folate in pregnancy and imprinted gene and repeat element methylation in the offspring
    • Haggarty P, Hoad G, Campbell DM, et al. Folate in pregnancy and imprinted gene and repeat element methylation in the offspring. Am J Clin Nutr 2013; 97: 94-99.
    • (2013) Am J Clin Nutr , vol.97 , pp. 94-99
    • Haggarty, P.1    Hoad, G.2    Campbell, D.M.3
  • 28
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010; 363: 2424-2433.
    • (2010) N Engl J Med , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 29
    • 84901429351 scopus 로고    scopus 로고
    • DNA methyl transferase (DNMT) gene polymorphisms could be a primary event in epigenetic susceptibility to schizophrenia
    • Saradalekshmi KR, Neetha NV, Sathyan S, et al. DNA methyl transferase (DNMT) gene polymorphisms could be a primary event in epigenetic susceptibility to schizophrenia. PLoS One 2014; 9: E98182.
    • (2014) PLoS One , vol.9 , pp. e98182
    • Saradalekshmi, K.R.1    Neetha, N.V.2    Sathyan, S.3
  • 30
    • 84906833959 scopus 로고    scopus 로고
    • Identification of a melanoma susceptibility locus and somatic mutation in TET2
    • Song F, Amos CI, Lee JE, et al. Identification of a melanoma susceptibility locus and somatic mutation in TET2. Carcinogenesis 2014; 35: 2097-2101.
    • (2014) Carcinogenesis , vol.35 , pp. 2097-2101
    • Song, F.1    Amos, C.I.2    Lee, J.E.3
  • 31
    • 84893090129 scopus 로고    scopus 로고
    • Epigenetic consequences of a changing human diet
    • Haggarty P. Epigenetic consequences of a changing human diet. Proc Nutr Soc 2013; 72: 363-371.
    • (2013) Proc Nutr Soc , vol.72 , pp. 363-371
    • Haggarty, P.1
  • 32
    • 84908125109 scopus 로고    scopus 로고
    • Supplementation with N-3 longchain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells
    • Hoile SP, Clarke-Harris R, Huang RC, et al. Supplementation with N-3 longchain polyunsaturated fatty acids or olive oil in men and women with renal disease induces differential changes in the DNA methylation of FADS2 and ELOVL5 in peripheral blood mononuclear cells. PLoS One 2014; 9: E109896.
    • (2014) PLoS One , vol.9 , pp. e109896
    • Hoile, S.P.1    Clarke-Harris, R.2    Huang, R.C.3
  • 33
    • 84892680128 scopus 로고    scopus 로고
    • PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects: Impact of 5 days of high-fat overfeeding
    • Gillberg L, Jacobsen SC, Ronn T, et al. PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects: Impact of 5 days of high-fat overfeeding. Metabolism 2014; 63: 263-271.
    • (2014) Metabolism , vol.63 , pp. 263-271
    • Gillberg, L.1    Jacobsen, S.C.2    Ronn, T.3
  • 34
    • 84902987423 scopus 로고    scopus 로고
    • Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets
    • Hall E, Volkov P, Dayeh T, et al. Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets. BMC Med 2014; 12: 103.
    • (2014) BMC Med , vol.12 , pp. 103
    • Hall, E.1    Volkov, P.2    Dayeh, T.3
  • 35
    • 84861852370 scopus 로고    scopus 로고
    • Are sirtuins viable targets for improving healthspan and lifespan?
    • Baur JA, Ungvari Z, Minor RK, et al. Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov 2012; 11: 443-461.
    • (2012) Nat Rev Drug Discov , vol.11 , pp. 443-461
    • Baur, J.A.1    Ungvari, Z.2    Minor, R.K.3
  • 36
    • 84858654396 scopus 로고    scopus 로고
    • Socio-economic status is associated with epigenetic differences in the pSoBid cohort
    • McGuinness D, McGlynn LM, Johnson PC, et al. Socio-economic status is associated with epigenetic differences in the pSoBid cohort. Int J Epidemiol 2012; 41: 151-160.
    • (2012) Int J Epidemiol , vol.41 , pp. 151-160
    • McGuinness, D.1    McGlynn, L.M.2    Johnson, P.C.3
  • 37
    • 84858657971 scopus 로고    scopus 로고
    • Associations with early-life socioeconomic position in adult DNA methylation
    • Borghol N, Suderman M, McArdle W, et al. Associations with early-life socioeconomic position in adult DNA methylation. Int J Epidemiol 2012; 41: 62-74.
    • (2012) Int J Epidemiol , vol.41 , pp. 62-74
    • Borghol, N.1    Suderman, M.2    McArdle, W.3
  • 38
    • 80052584384 scopus 로고    scopus 로고
    • Methylation patterns in sentinel genes in peripheral blood cells of heavy smokers: Influence of cruciferous vegetables in an intervention study
    • Scoccianti C, Ricceri F, Ferrari P, et al. Methylation patterns in sentinel genes in peripheral blood cells of heavy smokers: Influence of cruciferous vegetables in an intervention study. Epigenetics 2011; 6: 1114-1119.
    • (2011) Epigenetics , vol.6 , pp. 1114-1119
    • Scoccianti, C.1    Ricceri, F.2    Ferrari, P.3
  • 39
    • 77449083293 scopus 로고    scopus 로고
    • Epigenetics and the environmental regulation of the genome and its function
    • Zhang TY, Meaney MJ. Epigenetics and the environmental regulation of the genome and its function. Annu Rev Psychol 2010; 61: 439-443.
    • (2010) Annu Rev Psychol , vol.61 , pp. 439-443
    • Zhang, T.Y.1    Meaney, M.J.2
  • 40
    • 84906100296 scopus 로고    scopus 로고
    • Parenting from before conception
    • Lane M, Robker RL, Robertson SA. Parenting from before conception. Science 2014; 345: 756-760.
    • (2014) Science , vol.345 , pp. 756-760
    • Lane, M.1    Robker, R.L.2    Robertson, S.A.3
  • 41
    • 84858253017 scopus 로고    scopus 로고
    • Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: Prospective results from a folate-replete population
    • Boeke CE, Baccarelli A, Kleinman KP, et al. Gestational intake of methyl donors and global LINE-1 DNA methylation in maternal and cord blood: Prospective results from a folate-replete population. Epigenetics 2012; 7: 253-260.
    • (2012) Epigenetics , vol.7 , pp. 253-260
    • Boeke, C.E.1    Baccarelli, A.2    Kleinman, K.P.3
  • 42
    • 84873253940 scopus 로고    scopus 로고
    • Paternal obesity is associated with IGF2 hypomethylation in newborns: Results from a Newborn Epigenetics Study (NEST) cohort
    • Soubry A, Schildkraut JM, Murtha A, et al. Paternal obesity is associated with IGF2 hypomethylation in newborns: Results from a Newborn Epigenetics Study (NEST) cohort. BMC Med 2013; 11: 29.
    • (2013) BMC Med , vol.11 , pp. 29
    • Soubry, A.1    Schildkraut, J.M.2    Murtha, A.3
  • 43
    • 84914164721 scopus 로고    scopus 로고
    • Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants
    • Lee HS, Barraza-Villarreal A, Biessy C, et al. Dietary supplementation with polyunsaturated fatty acid during pregnancy modulates DNA methylation at IGF2/H19 imprinted genes and growth of infants. Physiol Genomics 2014; 46: 851-857.
    • (2014) Physiol Genomics , vol.46 , pp. 851-857
    • Lee, H.S.1    Barraza-Villarreal, A.2    Biessy, C.3
  • 44
    • 84904563107 scopus 로고    scopus 로고
    • The role of genomic imprinting in biology and disease: An expanding view
    • Peters J. The role of genomic imprinting in biology and disease: An expanding view. Nat Rev Genet 2014; 15: 517-530.
    • (2014) Nat Rev Genet , vol.15 , pp. 517-530
    • Peters, J.1
  • 45
    • 79251579948 scopus 로고    scopus 로고
    • Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue
    • Woodfine K, Huddleston JE, Murrell A. Quantitative analysis of DNA methylation at all human imprinted regions reveals preservation of epigenetic stability in adult somatic tissue. Epigenet Chromatin 2011; 4: 1.
    • (2011) Epigenet Chromatin , vol.4 , pp. 1
    • Woodfine, K.1    Huddleston, J.E.2    Murrell, A.3
  • 46
    • 84892371264 scopus 로고    scopus 로고
    • Beckwith-Wiedemann and Russell-Silver syndromes: From new molecular insights to the comprehension of imprinting regulation
    • Azzi S, Abi HW, Netchine I. Beckwith-Wiedemann and Russell-Silver syndromes: From new molecular insights to the comprehension of imprinting regulation. Curr Opin Endocrinol Diabetes Obes 2014; 21: 30-38.
    • (2014) Curr Opin Endocrinol Diabetes Obes , vol.21 , pp. 30-38
    • Azzi, S.1    Abi, H.W.2    Netchine, I.3
  • 47
    • 84897935458 scopus 로고    scopus 로고
    • Prader-Willi-like phenotypes: A systematic review of their chromosomal abnormalities
    • Rocha CF, Paiva CL. Prader-Willi-like phenotypes: A systematic review of their chromosomal abnormalities. Genet Mol Res 2014; 13: 2290-2298.
    • (2014) Genet Mol Res , vol.13 , pp. 2290-2298
    • Rocha, C.F.1    Paiva, C.L.2
  • 48
    • 84901292089 scopus 로고    scopus 로고
    • Angelman syndrome: Review of clinical and molecular aspects
    • Bird LM. Angelman syndrome: Review of clinical and molecular aspects. Appl Clin Genet 2014; 7: 93-104.
    • (2014) Appl Clin Genet , vol.7 , pp. 93-104
    • Bird, L.M.1
  • 50
    • 84913603626 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived spontaneously
    • Lazaraviciute G, Kauser M, Bhattacharya S, et al. A systematic review and meta-analysis of DNA methylation levels and imprinting disorders in children conceived by IVF/ICSI compared with children conceived spontaneously. Hum Reprod Update 2014; 20: 840-852.
    • (2014) Hum Reprod Update , vol.20 , pp. 840-852
    • Lazaraviciute, G.1    Kauser, M.2    Bhattacharya, S.3
  • 51
    • 84902665540 scopus 로고    scopus 로고
    • Epigenetic status in the offspring of spontaneous and assisted conception
    • Whitelaw N, Bhattacharya S, Hoad G, et al. Epigenetic status in the offspring of spontaneous and assisted conception. Hum Reprod 2014; 29: 1452-1458.
    • (2014) Hum Reprod , vol.29 , pp. 1452-1458
    • Whitelaw, N.1    Bhattacharya, S.2    Hoad, G.3
  • 52
    • 28044436691 scopus 로고    scopus 로고
    • Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life
    • Weaver IC, Champagne FA, Brown SE, et al. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: Altering epigenetic marking later in life. J Neurosci 2005; 25: 11045-11054.
    • (2005) J Neurosci , vol.25 , pp. 11045-11054
    • Weaver, I.C.1    Champagne, F.A.2    Brown, S.E.3
  • 53
    • 84863341417 scopus 로고    scopus 로고
    • Reversal of cocaine-conditioned place preference through methyl supplementation in mice: Altering global DNA methylation in the prefrontal cortex
    • Tian W, Zhao M, Li M, et al. Reversal of cocaine-conditioned place preference through methyl supplementation in mice: Altering global DNA methylation in the prefrontal cortex. PLoS One 2012; 7: E33435.
    • (2012) PLoS One , vol.7 , pp. e33435
    • Tian, W.1    Zhao, M.2    Li, M.3
  • 54
    • 84922227196 scopus 로고    scopus 로고
    • Green tea polyphenol EGCG reverse cisplatin resistance of A549/DDP cell line through candidate genes demethylation
    • Zhang Y, Wang X, Han L, et al. Green tea polyphenol EGCG reverse cisplatin resistance of A549/DDP cell line through candidate genes demethylation. Biomed Pharmacother 2015; 69: 285-290.
    • (2015) Biomed Pharmacother , vol.69 , pp. 285-290
    • Zhang, Y.1    Wang, X.2    Han, L.3
  • 55
    • 84881476916 scopus 로고    scopus 로고
    • Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells
    • Blaschke K, Ebata KT, Karimi MM, et al. Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells. Nature 2013; 500: 222-226.
    • (2013) Nature , vol.500 , pp. 222-226
    • Blaschke, K.1    Ebata, K.T.2    Karimi, M.M.3
  • 56
    • 84924664088 scopus 로고    scopus 로고
    • Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: A randomized, double blind, crossover study
    • Cabo R, Hernes S, Slettan A, et al. Effect of genetic polymorphisms involved in folate metabolism on the concentration of serum folate and plasma total homocysteine (p-tHcy) in healthy subjects after short-term folic acid supplementation: A randomized, double blind, crossover study. Genes Nutr 2015; 10: 456.
    • (2015) Genes Nutr , vol.10 , pp. 456
    • Cabo, R.1    Hernes, S.2    Slettan, A.3
  • 57
    • 84927934049 scopus 로고    scopus 로고
    • Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: A systematic review and meta-analysis of trials and observational studies
    • Epub ahead of print
    • Tsang BL, Devine OJ, Cordero AM, et al. Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677C>T polymorphism and blood folate concentrations: A systematic review and meta-analysis of trials and observational studies. Am J Clin Nutr 2015. [Epub ahead of print]
    • (2015) Am J Clin Nutr
    • Tsang, B.L.1    Devine, O.J.2    Cordero, A.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.