Assessing the association between the methylenetetrahydrofolate reductase (MTHFR) 677>T polymorphism and blood folate concentrations: A systematic review and meta-analysis of trials and observational studies

American Journal of Clinical Nutrition

Volumn 101, Issue 6, 2015, Pages 1286-1294

  Tsang, Becky L ^e   Devine, Owen J ^d   Cordero, Amy M ^a   Marchetta, Claire M ^e   Mulinare, Joseph ^d   Mersereau, Patricia ^f   Guo, Jing ^c   Qi, Yan Ping ^d,e   Berry, Robert J ^a   Rosenthal, Jorge ^a   Crider, Krista S ^a   Hamner, Heather C ^b  

^a NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES   (United States)

^b NATIONAL CENTER FOR CHRONIC DISEASE PREVENTION AND HEALTH PROMOTION   (United States)

^c NCBDDD)   (United States)

^d CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

^e OAK RIDGE INSTITUTE FOR SCIENCE AND EDUCATION   (United States)

^f SciMetrika   (United States)

Author keywords

MTHFR; Neural tube defects; Plasma folate; Red blood cell folate; Serum folate

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); FOLIC ACID; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN;

ALLELE; ARTICLE; BAYES THEOREM; ERYTHROCYTE; FOLIC ACID BLOOD LEVEL; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENOTYPE; HUMAN; MICROBIOLOGY; OBSERVATIONAL STUDY; PROTEIN BINDING; SYSTEMATIC REVIEW; ADOLESCENT; ADULT; BLOOD; CHILD; FACTUAL DATABASE; FEMALE; GENETICS; META ANALYSIS; METABOLISM; MIDDLE AGED; NEURAL TUBE DEFECTS; RANDOMIZED CONTROLLED TRIAL (TOPIC); RISK FACTOR; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

LONCHOCARPUS GLAUCIFOLIUS;

ADOLESCENT; ADULT; ALLELES; CHILD; DATABASES, FACTUAL; FEMALE; FOLIC ACID; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; NEURAL TUBE DEFECTS; OBSERVATIONAL STUDY AS TOPIC; POLYMORPHISM, GENETIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RISK FACTORS; SENSITIVITY AND SPECIFICITY; YOUNG ADULT;

EID: 84927934049     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.114.099994     Document Type: Article

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