Progress and obstacles towards generating hematopoietic stem cells from pluripotent stem cells

Current Opinion in Hematology

Volumn 22, Issue 4, 2015, Pages 317-323

  Lee, Jungmin ^a,b   Dykstra, Brad ^c   Sackstein, Robert ^c   Rossi, Derrick J ^a,b,d  

^a Harvard University   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

Cell migration; Directed differentiation; Hematopoietic stem cell; Homing; Pluripotency; Pluripotent stem cell

Indexed keywords

16,16 DIMETHYLPROSTAGLANDIN E2; INDOLE DERIVATIVE; KRUPPEL LIKE FACTOR 4; MONOCYTE CHEMOTACTIC PROTEIN 1; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN INHIBITOR; SIRTUIN 1; STEMREGENIN 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SOX17; TRANSCRIPTION FACTOR SOX2; UM 171; UNCLASSIFIED DRUG; VALPROIC ACID; MOLECULAR LIBRARY;

CELL DIFFERENTIATION; CELL HOMING; HEMANGIOBLAST; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HUMAN; MESENCHYMAL STEM CELL; MESODERM; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; BIOLOGICAL THERAPY; CELL LINEAGE; CELL MOTION; CYTOLOGY; DRUG EFFECTS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; METABOLISM; MOLECULAR LIBRARY; PHARMACOLOGY; PROCEDURES; STEM CELL NICHE; TRENDS;

CELL DIFFERENTIATION; CELL LINEAGE; CELL MOVEMENT; CELL- AND TISSUE-BASED THERAPY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; HUMANS; PLURIPOTENT STEM CELLS; SMALL MOLECULE LIBRARIES; STEM CELL NICHE; TRANSCRIPTION FACTORS;

EID: 84942778956     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0000000000000147     Document Type: Review

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