-
1
-
-
33744758028
-
The role of PI3K/ AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis
-
DOI 10.1093/hmg/ddl112
-
Armstrong, L., Hughes, O., Yung, S., Hyslop, L., Stewart, R., Wappler, I., Peters, H., Walter, T., Stojkovic, P., Evans, J., et al. (2006). The role of PI3K/ AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis. Hum. Mol. Genet. 15, 1894-1913 (Pubitemid 43821780)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.11
, pp. 1894-1913
-
-
Armstrong, L.1
Hughes, O.2
Yung, S.3
Hyslop, L.4
Stewart, R.5
Wappler, I.6
Peters, H.7
Walter, T.8
Stojkovic, P.9
Evans, J.10
Stojkovic, M.11
Lako, M.12
-
2
-
-
22144487405
-
+ cord blood cells to stromal cell-derived factor-1/CXCL12
-
DOI 10.1182/blood-2004-10-4145
-
Basu, S., and Broxmeyer, H.E. (2005). Transforming growth factor-b1 modulates responses of CD34+ cord blood cells to stromal cell-derived factor-1/ CXCL12. Blood 106, 485-493. (Pubitemid 40981242)
-
(2005)
Blood
, vol.106
, Issue.2
, pp. 485-493
-
-
Basu, S.1
Broxmeyer, H.E.2
-
3
-
-
0033526067
-
Bone morphogenetic proteins regulate the developmental program of human hematopoietic stem cells
-
DOI 10.1084/jem.189.7.1139
-
Bhatia, M., Bonnet, D., Wu, D., Murdoch, B., Wrana, J., Gallacher, L., and Dick, J. (1999). Bone morphogenic proteins regulate the developmental program of human hematopoietic stem cells. J. Exp. Med. 189, 1139-1147. (Pubitemid 29169831)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.7
, pp. 1139-1147
-
-
Bhatia, M.1
Bonnet, D.2
Wu, D.3
Murdoch, B.4
Wrana, J.5
Gallacher, L.6
Dick, J.E.7
-
4
-
-
0037871588
-
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells
-
DOI 10.1182/blood-2003-03-0832
-
Chadwick, K., Wang, L., Li, L., Menendez, P., Murdoch, B., and Bhatia, M. (2003). Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood 102, 906-915. (Pubitemid 36917782)
-
(2003)
Blood
, vol.102
, Issue.3
, pp. 906-915
-
-
Chadwick, K.1
Wang, L.2
Li, L.3
Menendez, P.4
Murdoch, B.5
Rouleau, A.6
Bhatia, M.7
-
5
-
-
33748203633
-
Definitive-like erythroid cells derived from human embryonic stem cells coexpress high levels of embryonic and fetal globins with little or no adult globin
-
DOI 10.1182/blood-2005-11-011874
-
Chang, K.H., Nelson, A.M., Cao, H., Wang, L., Nakamoto, B., Ware, C.B., and Papayannopoulou, T. (2006). Definitive-like erythroid cells derived from human embryonic stem cells co-express high levels of embryonic and fetal globins with little or no adult globin. Blood 108, 1515-1523. (Pubitemid 44316116)
-
(2006)
Blood
, vol.108
, Issue.5
, pp. 1515-1523
-
-
Chang, K.-H.1
Nelson, A.M.2
Cao, H.3
Wang, L.4
Nakamoto, B.5
Ware, C.B.6
Papayannopoulou, T.7
-
6
-
-
0034813102
-
Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution
-
DOI 10.1016/S1074-7613(01)00190-X
-
Cumano, A., Ferraz, J.C., Klaine, M., Di Santo, J.P., and Godin, I. (2001). Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. Immunity 15, 477-485. (Pubitemid 32907394)
-
(2001)
Immunity
, vol.15
, Issue.3
, pp. 477-485
-
-
Cumano, A.1
Ferraz, J.C.2
Klaine, M.3
Di Santo, J.P.4
Godin, I.5
-
7
-
-
0018346005
-
Isolation of the pericellular matrix of human fibroblast cultures
-
Hedman, K., Kurkinen, M., Alitalo, K., Vaheri, A., Johansson, S., and Hook, M. (1979). Isolation of the pericellular matrix of human fibroblast cultures. J. Cell Biol. 81, 83-91. (Pubitemid 9148438)
-
(1979)
Journal of Cell Biology
, vol.81
, Issue.1
, pp. 83-91
-
-
Hedman, K.1
Kurkinen, M.2
Alitalo, K.3
-
8
-
-
0035845526
-
Hematopoietic colony-forming cells derived from human embryonic stem cells
-
DOI 10.1073/pnas.191362598
-
Kaufman, D.S., Hanson, E.T., Lewis, R.L., Auerbach, R., and Thomson, J.A. (2001). Hematopoietic colony-forming cells derived from human embryonic stem cells. Proc. Natl. Acad. Sci. USA 98, 10716-10721. (Pubitemid 32878687)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.19
, pp. 10716-10721
-
-
Kaufman, D.S.1
Hanson, E.T.2
Lewis, R.L.3
Auerbach, R.4
Thomson, J.A.5
-
9
-
-
33947587879
-
Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures
-
DOI 10.1182/blood-2006-09-047704
-
Kennedy, M., D'Souza, S.L., Lynch-Kattman, M., Schwantz, S., and Keller, G. (2007). Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures. Blood 109, 2679-2687. (Pubitemid 46482058)
-
(2007)
Blood
, vol.109
, Issue.7
, pp. 2679-2687
-
-
Kennedy, M.1
D'Souza, S.L.2
Lynch-Kattman, M.3
Schwantz, S.4
Keller, G.5
-
10
-
-
33749152535
-
Promotion of haematopoietic activity in embryonic stem cells by the aorta-gonad-mesonephros microenvironment
-
DOI 10.1016/j.yexcr.2006.08.001, PII S0014482706003132
-
Krassowska, A., Gordon-Keylock, S., Samuel, K., Gilchrist, D., Dzierzak, E., Oostendorp, R.A.J., Forrester, L.M., and Ansell, J.D. (2006). Haematopoetic activity in differentiating embryonic stem cells is enhanced by the aorta-gonad-mesonephros region. Exp. Cell Res. 312, 3595-3603. (Pubitemid 44470777)
-
(2006)
Experimental Cell Research
, vol.312
, Issue.18
, pp. 3595-3603
-
-
Krassowska, A.1
Gordon-Keylock, S.2
Samuel, K.3
Gilchrist, D.4
Dzierzak, E.5
Oostendorp, R.6
Forrester, L.M.7
Ansell, J.D.8
-
11
-
-
34848927475
-
Bone morphogenetic protein 4 modulates c-Kit expression and differentiation potential in murine embryonic aorta-gonad-mesonephros haematopoiesis in vitro
-
DOI 10.1111/j.1365-2141.2007.06795.x
-
Marshall, C., Sinclair, J., Thrasher, A., and Kinnon, C. (2007). Bone morphogenic protein 4 modulates c-kit expression and differentiation potential in murine embryonic aorta-gonads-mesonephros haematopoiesis in vitro. Br. J. Haematol. 139, 321-330. (Pubitemid 47493096)
-
(2007)
British Journal of Haematology
, vol.139
, Issue.2
, pp. 321-330
-
-
Marshall, C.J.1
Sinclair, J.C.2
Thrasher, A.J.3
Kinnon, C.4
-
12
-
-
0030595341
-
Definitive hematopoiesis is autonomously initiated by the AGM region
-
DOI 10.1016/S0092-8674(00)80165-8
-
Medvinsky, A., and Dzierzak, E. (1996). Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86, 897-906. (Pubitemid 26336794)
-
(1996)
Cell
, vol.86
, Issue.6
, pp. 897-906
-
-
Medvinsky, A.1
Dzierzak, E.2
-
13
-
-
33344461144
-
Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients
-
DOI 10.1182/blood-2005-05-1922
-
Narayan, A.D., Chase, J.L., Lewis, R.L., Tian, X., Kaufman, D.S., Thomson, J.A., and Zanjani, E.D. (2006). Human embryonic stem cell derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. Blood 107, 2180-2183. (Pubitemid 43289404)
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 2180-2183
-
-
Narayan, A.D.1
Chase, J.L.2
Lewis, R.L.3
Tian, X.4
Kaufman, D.S.5
Thomson, J.A.6
Zanjani, E.D.7
-
14
-
-
37549020639
-
Wnt, activin and BMP signalling regulate distinct stages in the developmental pathway from embryonic stem cells
-
Nostro, M.C., Cheng, X., Keller, G., and Gadue, P. (2008). Wnt, activin and BMP signalling regulate distinct stages in the developmental pathway from embryonic stem cells. Cell Stem Cell 2, 60-71.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 60-71
-
-
Nostro, M.C.1
Cheng, X.2
Keller, G.3
Gadue, P.4
-
15
-
-
0037082497
-
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity
-
DOI 10.1182/blood.V99.4.1183
-
Oostendorp, R.A.J., Harvey, K.N., Kusadasi, N., de Bruijn, M.F., Saris, C., Ploemacher, R.E., Medvinsky, A.L., and Dzierzak, E.A. (2002a). Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood 99, 1183-1189. (Pubitemid 34547069)
-
(2002)
Blood
, vol.99
, Issue.4
, pp. 1183-1189
-
-
Oostendorp, R.A.J.1
Harvey, K.N.2
Kusadasi, N.3
De Bruijn, M.F.T.R.4
Saris, C.5
Ploemacher, R.E.6
Medvinsky, A.L.7
Dzierzak, E.A.8
-
16
-
-
0037092512
-
Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis
-
Oostendorp, R.A.J., Medvinsky, A.J., Kusadasi, N., Nakayama, N., Harvey, K., Orelio, C., Ottersbach, K., Covey, T., Ploemacher, R.E., Saris, C., and Dzierzak, E. (2002b). Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis. J. Cell Sci. 115, 2099-2108. (Pubitemid 34746376)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.10
, pp. 2099-2108
-
-
Oostendorp, R.A.J.1
Medvinsky, A.J.2
Kusadasi, N.3
Nakayama, N.4
Harvey, K.5
Orelio, C.6
Ottersbach, K.7
Ploemacher, R.E.8
Saris, C.9
Dzierzak, E.10
-
17
-
-
16644392750
-
Generation of murine stromal cell lines: Models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region
-
Oostendorp, R.A.J., Harvey, K., and Dzierzak, E.A. (2005a). Generation of murine stromal cell lines: models for the microenvironment of the embryonic mouse aorta-gonads-mesonephros region. Methods Mol. Biol. 290, 163-172.
-
(2005)
Methods Mol. Biol.
, vol.290
, pp. 163-172
-
-
Oostendorp, R.A.J.1
Harvey, K.2
Dzierzak, E.A.3
-
18
-
-
20344370721
-
Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in cocultures
-
DOI 10.1634/stemcells.2004-0120
-
Oostendorp, R.A.J., Robin, C., Steinhoff, C., Marz, S., Brauer, R., Nuber, U.A., Dzierzak, E.A., and Peschel, C. (2005b). Long-term maintenance of hematopoietic stem cells does not require contact with embryo-derived stromal cells in co-cultures. Stem Cells 23, 842-851. (Pubitemid 40791799)
-
(2005)
Stem Cells
, vol.23
, Issue.6
, pp. 842-851
-
-
Oostendorp, R.A.J.1
Robin, C.2
Steinhoff, C.3
Marz, S.4
Brauer, R.5
Nuber, U.A.6
Dzierzak, E.A.7
Peschel, C.8
-
19
-
-
3042733135
-
A hierarchical order of factors in the generation of FLK1- and SCL- expressing hematopoietic and endothelial progenitors from embryonic stem cells
-
DOI 10.1242/dev.01130
-
Park, C., Afrikanova, I., Chung, Y.S., Zhang, W.J., Arentson, E., Fong, G.H., Rosendahl, A., and Choi, K. (2004). A hierarchical order of factors in the generation of FLK-1 and SCL expressing hematopoietic and endothelial progenitors from embryonic stem cells. Development 131, 2749-2762. (Pubitemid 38877906)
-
(2004)
Development
, vol.131
, Issue.11
, pp. 2749-2762
-
-
Park, C.1
Afrikanova, I.2
Chung, Y.S.3
Zhang, W.J.4
Arentson, E.5
Fong, G.H.6
Rosendahl, A.7
Choi, K.8
-
20
-
-
34548595361
-
Endoglin is required for hemangioblast and early hematopoietic development
-
DOI 10.1242/dev.002907
-
Perlingeiro, R.C. (2007). Endoglin is required for hemangioblast and early hematopoietic development. Development 134, 3041-3048. (Pubitemid 47386915)
-
(2007)
Development
, vol.134
, Issue.16
, pp. 3041-3048
-
-
Perlingeiro, R.C.R.1
-
21
-
-
28844443906
-
Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development
-
DOI 10.1016/j.exphem.2005.09.003, PII S0301472X05004546
-
Qiu, C., Hanson, E., Olivier, E., Inada, M., Kaufman, D.S., Gupta, S., and Bouhassira, E.E. (2005). Differentiation of human embryonic stem cells into hematopoietic cells by coculture with human fetal liver cells recapitulates the globin switch that occurs early in development. Exp. Hematol. 33, 1450-1458. (Pubitemid 41773845)
-
(2005)
Experimental Hematology
, vol.33
, Issue.12
, pp. 1450-1458
-
-
Qiu, C.1
Hanson, E.2
Olivier, E.3
Inada, M.4
Kaufman, D.S.5
Gupta, S.6
Bouhassira, E.E.7
-
22
-
-
24644475227
-
Autocrine transforming growth factor-β regulation of hematopoiesis: Many outcomes that depend on the context
-
DOI 10.1038/sj.onc.1208921, PII 1208921
-
Ruscetti, F., Akel, S., and Bartelmez, S. (2005). Autocrine transforming growth factor-b regulation of hematopoiesis: many outcomes that depend on the context. Oncogene 24, 5751-5763. (Pubitemid 43086135)
-
(2005)
Oncogene
, vol.24
, Issue.37
, pp. 5751-5763
-
-
Ruscetti, F.W.1
Akel, S.2
Bartelmez, S.H.3
-
23
-
-
36749023976
-
HOXB4's road map to stem cell expansion
-
DOI 10.1073/pnas.0703082104
-
Schiedlmeier, B., Santos, A.C., Ribeiro, A., Moncaut, N., Lesinski, D., Auer, H., Kornacker, K., Ostertag, W., Baum, C., Mallo, M., and Klump, H. (2007). HOXB4's road map to stem cell expansion. Proc. Natl. Acad. Sci. USA 104, 16952-16957. (Pubitemid 350210971)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.43
, pp. 16952-16957
-
-
Schiedlmeier, B.1
Santos, A.C.2
Ribeiro, A.3
Moncaut, N.4
Lesinski, D.5
Auer, H.6
Kornacker, K.7
Ostertag, W.8
Baum, C.9
Mallo, M.10
Klump, H.11
-
24
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
DOI 10.1016/j.cell.2007.11.019, PII S0092867407014717
-
Takahashi, K., Tanabe, K., Ohnuki, M., Narita, M., Ichisaka, T., Tomoda, K., and Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131, 861-872. (Pubitemid 350138099)
-
(2007)
Cell
, vol.131
, Issue.5
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
25
-
-
0037082481
-
Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow
-
DOI 10.1182/blood.V99.4.1190
-
Takeuchi, M., Sekiguchi, T., Hara, T., Kinoshita, T., and Miyajima, A. (2002). Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow. Blood 99, 1190-1196. (Pubitemid 34547070)
-
(2002)
Blood
, vol.99
, Issue.4
, pp. 1190-1196
-
-
Takeuchi, M.1
Sekiguchi, T.2
Hara, T.3
Kinoshita, T.4
Miyajima, A.5
-
26
-
-
6944229647
-
Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells
-
DOI 10.1016/j.exphem.2004.06.013, PII S0301472X04002565
-
Tian, X., Woll, P.S., Morris, J.K., Linehan, J.L., and Kauffman, D. (2004). Cytokine requirements differ for stroma and embryoid body-mediated hematopoiesis from human embryonic stem cells. Exp. Hematol. 32, 1000-1009. (Pubitemid 39410714)
-
(2004)
Experimental Hematology
, vol.32
, Issue.10
, pp. 1000-1009
-
-
Tian, X.1
Morris, J.K.2
Linehan, J.L.3
Kaufman, D.S.4
-
27
-
-
33746897865
-
Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity
-
DOI 10.1634/stemcells.2005-0340
-
Tian, X., Woll, P.S., Morris, J.K., Linehan, J.I., and Kaufman, D. (2006). Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity. Stem Cells 24, 1370-1380. (Pubitemid 44464705)
-
(2006)
Stem Cells
, vol.24
, Issue.5
, pp. 1370-1380
-
-
Tian, X.1
Woll, P.S.2
Morris, J.K.3
Linehan, J.L.4
Kaufman, D.S.5
-
28
-
-
11244285402
-
+ cells: Efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential
-
DOI 10.1182/blood-2004-04-1649
-
Vodyanik, M.A., Bork, J.A., Thomson, J.A., and Slukvin, I.I. (2005). Human embryonic stem cell-derived CD34+ cells: efficient production in the coculture with OP9 stromal cells and analysis of lymphohematopoietic potential. Blood 105, 617-626. (Pubitemid 40070744)
-
(2005)
Blood
, vol.105
, Issue.2
, pp. 617-626
-
-
Vodyanik, M.A.1
Bork, J.A.2
Thomson, J.A.3
Slukvin, I.I.4
-
29
-
-
3142776112
-
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties
-
DOI 10.1016/j.immuni.2004.06.006, PII S1074761304001669
-
Wang, L., Shojaei, F., Levac, K., Cerdan, C., Menendez, P., Martin, T., Rouleau, A., and Bhatia, M. (2004). Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity 21, 31-41. (Pubitemid 38925265)
-
(2004)
Immunity
, vol.21
, Issue.1
, pp. 31-41
-
-
Wang, L.1
Li, L.2
Shojaei, F.3
Levac, K.4
Cerdan, C.5
Menendez, P.6
Martin, T.7
Rouleau, A.8
Bhatia, M.9
-
30
-
-
19344361972
-
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression
-
DOI 10.1084/jem.20041888
-
Wang, L., Menendez, P., Shojaei, F., Li, L., Mazurier, F., Dick, J.E., Cerdan, C., Levac, K., and Bhatia, M. (2005). Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J. Exp. Med. 201, 1603-1614. (Pubitemid 40721004)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.10
, pp. 1603-1614
-
-
Wang, L.1
Menendez, P.2
Shojaei, F.3
Li, L.4
Mazurier, F.5
Dick, J.E.6
Cerdan, C.7
Levac, K.8
Bhatia, M.9
-
31
-
-
36749043230
-
Induced pluripotent stem cell lines derived from human somatic cells
-
Yu, J., Vodyanik, M.A., Smuga-Otto, K., Antosiewicz-Bourget, J., Frane, J.L., Tian, S., Nie, J., Jonsdottir, G.A., Ruotti, V., Stewart, R., et al. (2007). Induced pluripotent stem cell lines derived from human somatic cells. Science 318, 1917-1920.
-
(2007)
Science
, vol.318
, pp. 1917-1920
-
-
Yu, J.1
Vodyanik, M.A.2
Smuga-Otto, K.3
Antosiewicz-Bourget, J.4
Frane, J.L.5
Tian, S.6
Nie, J.7
Jonsdottir, G.A.8
Ruotti, V.9
Stewart, R.10
-
32
-
-
39349091570
-
Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells
-
Zhang, P., Li, J., Tan, Z., Wang, C., Liu, T., Chen, L., Yong, J., Jiang, W., Sun, X., Du, L., et al. (2007). Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells. Blood 111, 1933-1941.
-
(2007)
Blood
, vol.111
, pp. 1933-1941
-
-
Zhang, P.1
Li, J.2
Tan, Z.3
Wang, C.4
Liu, T.5
Chen, L.6
Yong, J.7
Jiang, W.8
Sun, X.9
Du, L.10
|