Extracellular Juxtamembrane Segment of ADAM17 Interacts with Membranes and Is Essential for Its Shedding Activity

Biochemistry

Volumn 54, Issue 38, 2015, Pages 5791-5801

  Düsterhöft, Stefan ^a   Michalek, Matthias ^b   Kordowski, Felix ^b   Oldefest, Mirja ^a   Sommer, Anselm ^c   Röseler, Jona ^a   Reiss, Karina ^c   Grötzinger, Joachim ^a   Lorenzen, Inken ^a  

^a Kiel and Lungen Clinic Grosshansdorf   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

LIPID BILAYERS;

AMINO ACID RESIDUES; BIOLOGICAL PROCESS; CANCER PROGRESSION; DYNAMIC INTERACTION; EXTRACELLULAR REGION; METALLO-PROTEASE; SUBSTRATE RECOGNITION; TUMOR NECROSIS FACTORS;

SUBSTRATES;

LIPOSOME; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; ADAM PROTEIN; LIPID BILAYER; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ADSORPTION; ANIMAL CELL; ARTICLE; CIRCULAR DICHROISM; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DISSOCIATION CONSTANT; EMBRYO; ENZYME SUBSTRATE; EXTRACELLULAR MATRIX; FLUORESCENCE SPECTROSCOPY; LIPID BILAYER; LIPID COMPOSITION; MEMBRANE BINDING; MOLECULAR RECOGNITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; STATIC ELECTRICITY; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CELL MEMBRANE; CHEMICAL PHENOMENA; ENZYME SPECIFICITY; GENETICS; HEPG2 CELL LINE; HUMAN; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN DOMAIN;

ADAM PROTEINS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; CELL MEMBRANE; HEP G2 CELLS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LIPID BILAYERS; MICE; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; SUBSTRATE SPECIFICITY;

EID: 84942694202     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00497     Document Type: Article

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