-
1
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J., Slack, J. L., Reddy, P., Stocking, K. L., Sunnarborg, S. W., Lee, D. C., Russell, W. E., Castner, B. J., Johnson, R. S., Fitzner, J. N., Boyce, R. W., Nelson, N., Kozlosky, C. J., Wolfson, M. F., Rauch, C. T., Cerretti, D. P., Paxton, R. J., March, C. J., and Black, R. A. (1998) An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
Slack, J.L.2
Reddy, P.3
Stocking, K.L.4
Sunnarborg, S.W.5
Lee, D.C.6
Russell, W.E.7
Castner, B.J.8
Johnson, R.S.9
Fitzner, J.N.10
Boyce, R.W.11
Nelson, N.12
Kozlosky, C.J.13
Wolfson, M.F.14
Rauch, C.T.15
Cerretti, D.P.16
Paxton, R.J.17
March, C.J.18
Black, R.A.19
-
2
-
-
77955348535
-
Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice
-
Chalaris, A., Adam, N., Sina, C., Rosenstiel, P., Lehmann-Koch, J., Schirmacher, P., Hartmann, D., Cichy, J., Gavrilova, O., Schreiber, S., Jostock, T., Matthews, V., Häsler, R., Becker, C., Neurath, M. F., Reiss, K., Saftig, P., Scheller, J., and Rose-John, S. (2010) Critical role of the disintegrin metalloprotease ADAM17 for intestinal inflammation and regeneration in mice. J. Exp. Med. 207, 1617-1624
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1617-1624
-
-
Chalaris, A.1
Adam, N.2
Sina, C.3
Rosenstiel, P.4
Lehmann-Koch, J.5
Schirmacher, P.6
Hartmann, D.7
Cichy, J.8
Gavrilova, O.9
Schreiber, S.10
Jostock, T.11
Matthews, V.12
Häsler, R.13
Becker, C.14
Neurath, M.F.15
Reiss, K.16
Saftig, P.17
Scheller, J.18
Rose-John, S.19
-
3
-
-
38449086094
-
Cutting edge: TNF-α-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock
-
Horiuchi, K., Kimura, T., Miyamoto, T., Takaishi, H., Okada, Y., Toyama, Y., and Blobel, C. P. (2007) Cutting edge: TNF-α-converting enzyme (TACE/ADAM17) inactivation in mouse myeloid cells prevents lethality from endotoxin shock. J. Immunol. 179, 2686-2689
-
(2007)
J. Immunol.
, vol.179
, pp. 2686-2689
-
-
Horiuchi, K.1
Kimura, T.2
Miyamoto, T.3
Takaishi, H.4
Okada, Y.5
Toyama, Y.6
Blobel, C.P.7
-
4
-
-
63649105591
-
The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer
-
Pruessmeyer, J., and Ludwig, A. (2009) The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer. Semin. Cell Dev. Biol. 20, 164-174
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 164-174
-
-
Pruessmeyer, J.1
Ludwig, A.2
-
5
-
-
79960923986
-
ADAM17: A molecular switch to control inflammation and tissue regeneration
-
Scheller, J., Chalaris, A., Garbers, C., and Rose-John, S. (2011) ADAM17: a molecular switch to control inflammation and tissue regeneration. Trends Immunol. 32, 380-387
-
(2011)
Trends Immunol.
, vol.32
, pp. 380-387
-
-
Scheller, J.1
Chalaris, A.2
Garbers, C.3
Rose-John, S.4
-
6
-
-
0141509970
-
Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-α-converting enzyme (ADAM 17)
-
Garton, K. J., Gough, P. J., Philalay, J., Wille, P. T., Blobel, C. P., Whitehead, R. H., Dempsey, P. J., and Raines, E. W. (2003) Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-α-converting enzyme (ADAM 17). J. Biol. Chem. 278, 37459-37464
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 37459-37464
-
-
Garton, K.J.1
Gough, P.J.2
Philalay, J.3
Wille, P.T.4
Blobel, C.P.5
Whitehead, R.H.6
Dempsey, P.J.7
Raines, E.W.8
-
7
-
-
10744227313
-
Leukocyte migration is regulated by L-selectin endoproteolytic release
-
Venturi, G. M., Tu, L., Kadono, T., Khan, A. I., Fujimoto, Y., Oshel, P., Bock, C. B., Miller, A. S., Albrecht, R. M., Kubes, P., Steeber, D. A., and Tedder, T. F. (2003) Leukocyte migration is regulated by L-selectin endoproteolytic release. Immunity 19, 713-724
-
(2003)
Immunity
, vol.19
, pp. 713-724
-
-
Venturi, G.M.1
Tu, L.2
Kadono, T.3
Khan, A.I.4
Fujimoto, Y.5
Oshel, P.6
Bock, C.B.7
Miller, A.S.8
Albrecht, R.M.9
Kubes, P.10
Steeber, D.A.11
Tedder, T.F.12
-
8
-
-
8044257704
-
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
-
Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., Nelson, N., Boiani, N., Schooley, K. A., Gerhart, M., Davis, R., Fitzner, J. N., Johnson, R. S., Paxton, R. J., March, C. J., and Cerretti, D. P. (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells. Nature 385, 729-733
-
(1997)
Nature
, vol.385
, pp. 729-733
-
-
Black, R.A.1
Rauch, C.T.2
Kozlosky, C.J.3
Peschon, J.J.4
Slack, J.L.5
Wolfson, M.F.6
Castner, B.J.7
Stocking, K.L.8
Reddy, P.9
Srinivasan, S.10
Nelson, N.11
Boiani, N.12
Schooley, K.A.13
Gerhart, M.14
Davis, R.15
Fitzner, J.N.16
Johnson, R.S.17
Paxton, R.J.18
March, C.J.19
Cerretti, D.P.20
more..
-
9
-
-
8044250278
-
Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α
-
Moss, M. L., Jin, S. L., Milla, M. E., Bickett, D. M., Burkhart, W., Carter, H. L., Chen, W. J., Clay, W. C., Didsbury, J. R., Hassler, D., Hoffman, C. R., Kost, T. A., Lambert, M. H., Leesnitzer, M. A., McCauley, P., McGeehan, G., Mitchell, J., Moyer, M., Pahel, G., Rocque, W., Overton, L. K., Schoenen, F., Seaton, T., Su, J. L., and Becherer, J. D. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α. Nature 385, 733-736
-
(1997)
Nature
, vol.385
, pp. 733-736
-
-
Moss, M.L.1
Jin, S.L.2
Milla, M.E.3
Bickett, D.M.4
Burkhart, W.5
Carter, H.L.6
Chen, W.J.7
Clay, W.C.8
Didsbury, J.R.9
Hassler, D.10
Hoffman, C.R.11
Kost, T.A.12
Lambert, M.H.13
Leesnitzer, M.A.14
McCauley, P.15
McGeehan, G.16
Mitchell, J.17
Moyer, M.18
Pahel, G.19
Rocque, W.20
Overton, L.K.21
Schoenen, F.22
Seaton, T.23
Su, J.L.24
Becherer, J.D.25
more..
-
10
-
-
0034640286
-
Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme
-
Reddy, P., Slack, J. L., Davis, R., Cerretti, D. P., Kozlosky, C. J., Blanton, R. A., Shows, D., Peschon, J. J., and Black, R. A. (2000) Functional analysis of the domain structure of tumor necrosis factor-α converting enzyme. J. Biol. Chem. 275, 14608-14614
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14608-14614
-
-
Reddy, P.1
Slack, J.L.2
Davis, R.3
Cerretti, D.P.4
Kozlosky, C.J.5
Blanton, R.A.6
Shows, D.7
Peschon, J.J.8
Black, R.A.9
-
11
-
-
0027428924
-
Differential shedding of the two subunits of the interleukin-6 receptor
-
Müllberg, J., Dittrich, E., Graeve, L., Gerhartz, C., Yasukawa, K., Taga, T., Kishimoto, T., Heinrich, P. C., and Rose-John, S. (1993) Differential shedding of the two subunits of the interleukin-6 receptor. FEBS Lett. 332, 174-178
-
(1993)
FEBS Lett.
, vol.332
, pp. 174-178
-
-
Müllberg, J.1
Dittrich, E.2
Graeve, L.3
Gerhartz, C.4
Yasukawa, K.5
Taga, T.6
Kishimoto, T.7
Heinrich, P.C.8
Rose-John, S.9
-
12
-
-
0033395850
-
Shedding of soluble receptor for tumor necrosis factor α induced by M. Leprae or LPS from human mononuclear cells
-
Santos, D. O., Lorré, K., de Boer, M., and Van Heuverswyn, H. (1999) Shedding of soluble receptor for tumor necrosis factor α induced by M. leprae or LPS from human mononuclear cells. Nihon Hansenbyo Gakkai Zasshi 68, 185-193
-
(1999)
Nihon Hansenbyo Gakkai Zasshi
, vol.68
, pp. 185-193
-
-
Santos, D.O.1
Lorré, K.2
De Boer, M.3
Van Heuverswyn, H.4
-
13
-
-
34347391898
-
Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages
-
Bell, J. H., Herrera, A. H., Li, Y., and Walcheck, B. (2007) Role of ADAM17 in the ectodomain shedding of TNF-α and its receptors by neutrophils and macrophages. J. Leukocyte Biol. 82, 173-176
-
(2007)
J. Leukocyte Biol.
, vol.82
, pp. 173-176
-
-
Bell, J.H.1
Herrera, A.H.2
Li, Y.3
Walcheck, B.4
-
14
-
-
84867818285
-
A role for cGMP in inducible nitric-oxide synthase (iNOS) - Induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes
-
Chanthaphavong, R. S., Loughran, P. A., Lee, T. Y., Scott, M. J., and Billiar, T. R. (2012) A role for cGMP in inducible nitric-oxide synthase (iNOS) - induced tumor necrosis factor (TNF) α-converting enzyme (TACE/ADAM17) activation, translocation, and TNF receptor 1 (TNFR1) shedding in hepatocytes. J. Biol. Chem. 287, 35887-35898
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 35887-35898
-
-
Chanthaphavong, R.S.1
Loughran, P.A.2
Lee, T.Y.3
Scott, M.J.4
Billiar, T.R.5
-
15
-
-
33748848714
-
Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: Role in inflammation and cancer
-
Rose-John, S., Scheller, J., Elson, G., and Jones, S. (2006) Interleukin-6 biology is coordinated by membrane-bound and soluble receptors: role in inflammation and cancer. J. Leukocyte Biol. 80, 227-236
-
(2006)
J. Leukocyte Biol.
, vol.80
, pp. 227-236
-
-
Rose-John, S.1
Scheller, J.2
Elson, G.3
Jones, S.4
-
16
-
-
79955650634
-
The pro- and anti-inflammatory properties of the cytokine interleukin-6
-
Scheller, J., Chalaris, A., Schmidt-Arras, D., and Rose-John, S. (2011) The pro- and anti-inflammatory properties of the cytokine interleukin-6. Biochim. Biophys. Acta 1813, 878-888
-
(2011)
Biochim. Biophys. Acta
, vol.1813
, pp. 878-888
-
-
Scheller, J.1
Chalaris, A.2
Schmidt-Arras, D.3
Rose-John, S.4
-
17
-
-
80052358980
-
Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling
-
Jones, S. A., Scheller, J., and Rose-John, S. (2011) Therapeutic strategies for the clinical blockade of IL-6/gp130 signaling. J. Clin. Invest. 121, 3375-3383
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 3375-3383
-
-
Jones, S.A.1
Scheller, J.2
Rose-John, S.3
-
18
-
-
26844448800
-
Adam meets Eph: An ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans
-
Janes, P. W., Saha, N., Barton, W. A., Kolev, M. V., Wimmer-Kleikamp, S. H., Nievergall, E., Blobel, C. P., Himanen, J. P., Lackmann, M., and Nikolov, D. B. (2005) Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans. Cell 123, 291-304
-
(2005)
Cell
, vol.123
, pp. 291-304
-
-
Janes, P.W.1
Saha, N.2
Barton, W.A.3
Kolev, M.V.4
Wimmer-Kleikamp, S.H.5
Nievergall, E.6
Blobel, C.P.7
Himanen, J.P.8
Lackmann, M.9
Nikolov, D.B.10
-
19
-
-
84876476723
-
Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase
-
Düsterhöft, S., Jung, S., Hung, C. W., Tholey, A., Sönnichsen, F. D., Grötzinger, J., and Lorenzen, I. (2013) Membrane-proximal domain of a disintegrin and metalloprotease-17 represents the putative molecular switch of its shedding activity operated by protein-disulfide isomerase. J. Am. Chem. Soc. 135, 5776-5781
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 5776-5781
-
-
Düsterhöft, S.1
Jung, S.2
Hung, C.W.3
Tholey, A.4
Sönnichsen, F.D.5
Grötzinger, J.6
Lorenzen, I.7
-
20
-
-
63649149047
-
Three-dimensional domain architecture of the ADAM family proteinases
-
Takeda, S. (2009) Three-dimensional domain architecture of the ADAM family proteinases. Semin. Cell Dev. Biol. 20, 146-152
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 146-152
-
-
Takeda, S.1
-
21
-
-
65249090883
-
ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as TGFα, L-Selectin and TNFα
-
Le Gall, S. M., Bobé, P., Reiss, K., Horiuchi, K., Niu, X. D., Lundell, D., Gibb, D. R., Conrad, D., Saftig, P., and Blobel, C. P. (2009) ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as TGFα, L-Selectin and TNFα. Mol. Biol. Cell 20, 1785-1794
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 1785-1794
-
-
Le Gall, S.M.1
Bobé, P.2
Reiss, K.3
Horiuchi, K.4
Niu, X.D.5
Lundell, D.6
Gibb, D.R.7
Conrad, D.8
Saftig, P.9
Blobel, C.P.10
-
22
-
-
78649757591
-
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site
-
Le Gall, S. M., Maretzky, T., Issuree, P. D., Niu, X. D., Reiss, K., Saftig, P., Khokha, R., Lundell, D., and Blobel, C. P. (2010) ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site. J. Cell Sci. 123, 3913-3922
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3913-3922
-
-
Le Gall, S.M.1
Maretzky, T.2
Issuree, P.D.3
Niu, X.D.4
Reiss, K.5
Saftig, P.6
Khokha, R.7
Lundell, D.8
Blobel, C.P.9
-
23
-
-
2542423590
-
Integrin α5β1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells
-
Bax, D. V., Messent, A. J., Tart, J., van Hoang, M., Kott, J., Maciewicz, R. A., and Humphries, M. J. (2004) Integrin α5β1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells. J. Biol. Chem. 279, 22377-22386
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 22377-22386
-
-
Bax, D.V.1
Messent, A.J.2
Tart, J.3
Van Hoang, M.4
Kott, J.5
Maciewicz, R.A.6
Humphries, M.J.7
-
24
-
-
77953910301
-
Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase α subunit
-
Saha, A., Backert, S., Hammond, C. E., Gooz, M., and Smolka, A. J. (2010) Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase α subunit. Gastroenterology 139, 239-248
-
(2010)
Gastroenterology
, vol.139
, pp. 239-248
-
-
Saha, A.1
Backert, S.2
Hammond, C.E.3
Gooz, M.4
Smolka, A.J.5
-
25
-
-
84857875546
-
A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by α5β1 integrin in kidney mesangial cells
-
Gooz, P., Dang, Y., Higashiyama, S., Twal, W. O., Haycraft, C. J., and Gooz, M. (2012) A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by α5β1 integrin in kidney mesangial cells. PLoS ONE 7, e33350
-
(2012)
PLoS ONE
, vol.7
-
-
Gooz, P.1
Dang, Y.2
Higashiyama, S.3
Twal, W.O.4
Haycraft, C.J.5
Gooz, M.6
-
26
-
-
84876002140
-
The disintegrin domain of ADAM17 antagonises fibroblastcarcinoma cell interactions
-
Trad, A., Riese, M., Shomali, M., Hedeman, N., Effenberger, T., Grötzinger, J., and Lorenzen, I. (2013) The disintegrin domain of ADAM17 antagonises fibroblastcarcinoma cell interactions. Int. J. Oncol. 42, 1793-1800
-
(2013)
Int. J. Oncol.
, vol.42
, pp. 1793-1800
-
-
Trad, A.1
Riese, M.2
Shomali, M.3
Hedeman, N.4
Effenberger, T.5
Grötzinger, J.6
Lorenzen, I.7
-
27
-
-
33745731954
-
Crystal structures of VAP1 reveal ADAMs'MDCdomain architecture and its unique C-shaped scaffold
-
Takeda, S., Igarashi, T., Mori, H., and Araki, S. (2006) Crystal structures of VAP1 reveal ADAMs'MDCdomain architecture and its unique C-shaped scaffold. EMBO J. 25, 2388-2396
-
(2006)
EMBO J.
, vol.25
, pp. 2388-2396
-
-
Takeda, S.1
Igarashi, T.2
Mori, H.3
Araki, S.4
-
28
-
-
84859896499
-
The membrane-proximal domain of a disintegrin and metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II
-
Lorenzen, I., Lokau, J., Düsterhöft, S., Trad, A., Garbers, C., Scheller, J., Rose-John, S., and Grötzinger, J. (2012) The membrane-proximal domain of a disintegrin and metalloprotease 17 (ADAM17) is responsible for recognition of the interleukin-6 receptor and interleukin-1 receptor II. FEBS Lett. 586, 1093-1100
-
(2012)
FEBS Lett.
, vol.586
, pp. 1093-1100
-
-
Lorenzen, I.1
Lokau, J.2
Düsterhöft, S.3
Trad, A.4
Garbers, C.5
Scheller, J.6
Rose-John, S.7
Grötzinger, J.8
-
29
-
-
84855863627
-
Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain
-
Lorenzen, I., Trad, A., and Grötzinger, J. (2011) Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain. Biochem. Biophys. Res. Commun. 415, 330-336
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.415
, pp. 330-336
-
-
Lorenzen, I.1
Trad, A.2
Grötzinger, J.3
-
30
-
-
0032724176
-
Specific sequence elements are required for the expression of functional tumor necrosis factor-β-converting enzyme (TACE)
-
Milla, M. E., Leesnitzer, M. A., Moss, M. L., Clay, W. C., Carter, H. L., Miller, A. B., Su, J. L., Lambert, M. H., Willard, D. H., Sheeley, D. M., Kost, T. A., Burkhart, W., Moyer, M., Blackburn, R. K., Pahel, G. L., Mitchell, J. L., Hoffman, C. R., and Becherer, J. D. (1999) Specific sequence elements are required for the expression of functional tumor necrosis factor-β- converting enzyme (TACE). J. Biol. Chem. 274, 30563-30570
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30563-30570
-
-
Milla, M.E.1
Leesnitzer, M.A.2
Moss, M.L.3
Clay, W.C.4
Carter, H.L.5
Miller, A.B.6
Su, J.L.7
Lambert, M.H.8
Willard, D.H.9
Sheeley, D.M.10
Kost, T.A.11
Burkhart, W.12
Moyer, M.13
Blackburn, R.K.14
Pahel, G.L.15
Mitchell, J.L.16
Hoffman, C.R.17
Becherer, J.D.18
-
31
-
-
3042589336
-
Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-β converting enzyme (TACE)
-
Li, X., and Fan, H. (2004) Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-β converting enzyme (TACE). J. Biol. Chem. 279, 27365-27375
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27365-27375
-
-
Li, X.1
Fan, H.2
-
32
-
-
61449229249
-
Regulation of mature ADAM17 by redox agents for L-selectin shedding
-
Wang, Y., Herrera, A. H., Li, Y., Belani, K. K., and Walcheck, B. (2009) Regulation of mature ADAM17 by redox agents for L-selectin shedding. J. Immunol. 182, 2449-2457
-
(2009)
J. Immunol.
, vol.182
, pp. 2449-2457
-
-
Wang, Y.1
Herrera, A.H.2
Li, Y.3
Belani, K.K.4
Walcheck, B.5
-
33
-
-
77954902619
-
Thiol isomerases negatively regulate the cellular shedding activity of ADAM17
-
Willems, S. H., Tape, C. J., Stanley, P. L., Taylor, N. A., Mills, I. G., Neal, D. E., McCafferty, J., and Murphy, G. (2010) Thiol isomerases negatively regulate the cellular shedding activity of ADAM17. Biochem. J. 428, 439-450
-
(2010)
Biochem. J.
, vol.428
, pp. 439-450
-
-
Willems, S.H.1
Tape, C.J.2
Stanley, P.L.3
Taylor, N.A.4
Mills, I.G.5
Neal, D.E.6
McCafferty, J.7
Murphy, G.8
-
34
-
-
79955014374
-
Cross-domain inhibition of TACE ectodomain
-
Tape, C. J., Willems, S. H., Dombernowsky, S. L., Stanley, P. L., Fogarasi, M., Ouwehand, W., McCafferty, J., and Murphy, G. (2011) Cross-domain inhibition of TACE ectodomain. Proc. Natl. Acad. Sci. U. S. A. 108, 5578-5583
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 5578-5583
-
-
Tape, C.J.1
Willems, S.H.2
Dombernowsky, S.L.3
Stanley, P.L.4
Fogarasi, M.5
Ouwehand, W.6
McCafferty, J.7
Murphy, G.8
-
35
-
-
0027291015
-
Prediction of protein secondary structure at better than 70% accuracy
-
Rost, B., and Sander, C. (1993) Prediction of protein secondary structure at better than 70% accuracy. J. Mol. Biol. 232, 584-599
-
(1993)
J. Mol. Biol.
, vol.232
, pp. 584-599
-
-
Rost, B.1
Sander, C.2
-
36
-
-
51749085388
-
HELIQUEST: A Web server to screen sequences with specific β-helical properties
-
Gautier, R., Douguet, D., Antonny, B., and Drin, G. (2008) HELIQUEST: a Web server to screen sequences with specific β-helical properties. Bioinformatics 24, 2101-2102
-
(2008)
Bioinformatics
, vol.24
, pp. 2101-2102
-
-
Gautier, R.1
Douguet, D.2
Antonny, B.3
Drin, G.4
-
37
-
-
0025398721
-
WHAT IF: A molecular modeling and drug design program
-
Vriend, G. (1990) WHAT IF: a molecular modeling and drug design program. J. Mol. Graph. 8, 52-56
-
(1990)
J. Mol. Graph.
, vol.8
, pp. 52-56
-
-
Vriend, G.1
-
38
-
-
84879170482
-
Upd3: An ancestor of the four-helix bundle cytokines
-
Oldefest, M., Nowinski, J., Hung, C. W., Neelsen, D., Trad, A., Tholey, A., Grötzinger, J., and Lorenzen, I. (2013) Upd3: an ancestor of the four-helix bundle cytokines. Biochem. Biophys. Res. Commun. 436, 66-72
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.436
, pp. 66-72
-
-
Oldefest, M.1
Nowinski, J.2
Hung, C.W.3
Neelsen, D.4
Trad, A.5
Tholey, A.6
Grötzinger, J.7
Lorenzen, I.8
-
39
-
-
34548856204
-
Apoptosis is a natural stimulus of IL6R shedding and contributes to the pro-inflammatory transsignaling function of neutrophils
-
Chalaris, A., Rabe, B., Paliga, K., Lange, H., Laskay, T., Fielding, C. A., Jones, S. A., Rose-John, S., and Scheller, J. (2007) Apoptosis is a natural stimulus of IL6R shedding and contributes to the pro-inflammatory transsignaling function of neutrophils. Blood 110, 1748-1755
-
(2007)
Blood
, vol.110
, pp. 1748-1755
-
-
Chalaris, A.1
Rabe, B.2
Paliga, K.3
Lange, H.4
Laskay, T.5
Fielding, C.A.6
Jones, S.A.7
Rose-John, S.8
Scheller, J.9
-
40
-
-
84878247187
-
Minimal interleukin 6 (IL-6) receptor stalk composition for IL-6 receptor shedding and IL-6 classic signaling
-
Baran, P., Nitz, R., Grötzinger, J., Scheller, J., and Garbers, C. (2013) Minimal interleukin 6 (IL-6) receptor stalk composition for IL-6 receptor shedding and IL-6 classic signaling. J. Biol. Chem. 288, 14756-14768
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 14756-14768
-
-
Baran, P.1
Nitz, R.2
Grötzinger, J.3
Scheller, J.4
Garbers, C.5
-
41
-
-
79955456934
-
Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding
-
Garbers, C., Jänner, N., Chalaris, A., Moss, M. L., Floss, D. M., Meyer, D., Koch-Nolte, F., Rose-John, S., and Scheller, J. (2011) Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding. J. Biol. Chem. 286, 14804-14811
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 14804-14811
-
-
Garbers, C.1
Jänner, N.2
Chalaris, A.3
Moss, M.L.4
Floss, D.M.5
Meyer, D.6
Koch-Nolte, F.7
Rose-John, S.8
Scheller, J.9
-
43
-
-
84863205849
-
NIH Image to ImageJ: 25 years of image analysis
-
Schneider, C. A., Rasband, W. S., and Eliceiri, K. W. (2012) NIH Image to ImageJ: 25 years of image analysis. Nat. Meth. 9, 671-675
-
(2012)
Nat. Meth.
, vol.9
, pp. 671-675
-
-
Schneider, C.A.1
Rasband, W.S.2
Eliceiri, K.W.3
-
44
-
-
0027398766
-
The soluble interleukin-6 receptor is generated by shedding
-
Müllberg, J., Schooltink, H., Stoyan, T., Günther, M., Graeve, L., Buse, G., Mackiewicz, A., Heinrich, P. C., and Rose-John, S. (1993) The soluble interleukin-6 receptor is generated by shedding. Eur. J. Immunol. 23, 473-480
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 473-480
-
-
Müllberg, J.1
Schooltink, H.2
Stoyan, T.3
Günther, M.4
Graeve, L.5
Buse, G.6
Mackiewicz, A.7
Heinrich, P.C.8
Rose-John, S.9
-
45
-
-
33645798836
-
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
-
Roderfeld, M., Weiskirchen, R., Wagner, S., Berres, M. L., Henkel, C., Grötzinger, J., Gressner, A. M., Matern, S., and Roeb, E. (2006) Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice. FASEB J. 20, 444-454
-
(2006)
FASEB J.
, vol.20
, pp. 444-454
-
-
Roderfeld, M.1
Weiskirchen, R.2
Wagner, S.3
Berres, M.L.4
Henkel, C.5
Grötzinger, J.6
Gressner, A.M.7
Matern, S.8
Roeb, E.9
-
46
-
-
79956067767
-
Leukocyte ADAM17 regulates acute pulmonary inflammation
-
Arndt, P. G., Strahan, B., Wang, Y., Long, C., Horiuchi, K., and Walcheck, B. (2011) Leukocyte ADAM17 regulates acute pulmonary inflammation. PLoS ONE 6, e19938
-
(2011)
PLoS ONE
, vol.6
-
-
Arndt, P.G.1
Strahan, B.2
Wang, Y.3
Long, C.4
Horiuchi, K.5
Walcheck, B.6
-
47
-
-
84873292211
-
Architecture and membrane interactions of the EGF receptor
-
Arkhipov, A., Shan, Y., Das, R., Endres, N. F., Eastwood, M. P., Wemmer, D. E., Kuriyan, J., and Shaw, D. E. (2013) Architecture and membrane interactions of the EGF receptor. Cell 152, 557-569
-
(2013)
Cell
, vol.152
, pp. 557-569
-
-
Arkhipov, A.1
Shan, Y.2
Das, R.3
Endres, N.F.4
Eastwood, M.P.5
Wemmer, D.E.6
Kuriyan, J.7
Shaw, D.E.8
-
48
-
-
84873280409
-
Conformational coupling across the plasma membrane in activation of the EGF receptor
-
Endres, N. F., Das, R., Smith, A. W., Arkhipov, A., Kovacs, E., Huang, Y., Pelton, J. G., Shan, Y., Shaw, D. E., Wemmer, D. E., Groves, J. T., and Kuriyan, J. (2013) Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell 152, 543-556
-
(2013)
Cell
, vol.152
, pp. 543-556
-
-
Endres, N.F.1
Das, R.2
Smith, A.W.3
Arkhipov, A.4
Kovacs, E.5
Huang, Y.6
Pelton, J.G.7
Shan, Y.8
Shaw, D.E.9
Wemmer, D.E.10
Groves, J.T.11
Kuriyan, J.12
-
49
-
-
79960601577
-
Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry
-
Bi, S., Hong, P. W., Lee, B., and Baum, L. G. (2011) Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry. Proc. Natl. Acad. Sci. U. S. A. 108, 10650-10655
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 10650-10655
-
-
Bi, S.1
Hong, P.W.2
Lee, B.3
Baum, L.G.4
-
50
-
-
84864125078
-
Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of α3 integrins
-
Cho, J., Kennedy, D. R., Lin, L., Huang, M., Merrill-Skoloff, G., Furie, B. C., and Furie, B. (2012) Protein disulfide isomerase capture during thrombus formation in vivo depends on the presence of α3 integrins. Blood 120, 647-655
-
(2012)
Blood
, vol.120
, pp. 647-655
-
-
Cho, J.1
Kennedy, D.R.2
Lin, L.3
Huang, M.4
Merrill-Skoloff, G.5
Furie, B.C.6
Furie, B.7
-
51
-
-
34249295619
-
Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands
-
Kaiser, B. K., Yim, D., Chow, I. T., Gonzalez, S., Dai, Z., Mann, H. H., Strong, R. K., Groh, V., and Spies, T. (2007) Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. Nature 447, 482-486
-
(2007)
Nature
, vol.447
, pp. 482-486
-
-
Kaiser, B.K.1
Yim, D.2
Chow, I.T.3
Gonzalez, S.4
Dai, Z.5
Mann, H.H.6
Strong, R.K.7
Groh, V.8
Spies, T.9
-
52
-
-
84871339927
-
A protein disulfide isomerase/thioredoxin-1 complex is physically attached to exofacial membrane tumor necrosis factor receptors: Overexpression in chronic lymphocytic leukemia cells
-
Söderberg, A., Hossain, A., and Rosén, A. (2013) A protein disulfide isomerase/thioredoxin-1 complex is physically attached to exofacial membrane tumor necrosis factor receptors: overexpression in chronic lymphocytic leukemia cells. Antioxid. Redox Signal. 18, 363-375
-
(2013)
Antioxid. Redox Signal.
, vol.18
, pp. 363-375
-
-
Söderberg, A.1
Hossain, A.2
Rosén, A.3
-
53
-
-
41549150319
-
Interaction and functional association of protein disulfide isomerase with αVβ3 integrin on endothelial cells
-
Swiatkowska, M., Szymañski, J., Padula, G., and Cierniewski, C. S. (2008) Interaction and functional association of protein disulfide isomerase with αVβ3 integrin on endothelial cells. FEBS J. 275, 1813-1823
-
(2008)
FEBS J.
, vol.275
, pp. 1813-1823
-
-
Swiatkowska, M.1
Szymañski, J.2
Padula, G.3
Cierniewski, C.S.4
-
54
-
-
0032873455
-
KDEL proteins are found on the surface of NG108-15 cells
-
Xiao, G., Chung, T. F., Pyun, H. Y., Fine, R. E., and Johnson, R. J. (1999) KDEL proteins are found on the surface of NG108-15 cells. Brain Res. Mol. Brain Res. 72, 121-128
-
(1999)
Brain Res. Mol. Brain Res.
, vol.72
, pp. 121-128
-
-
Xiao, G.1
Chung, T.F.2
Pyun, H.Y.3
Fine, R.E.4
Johnson, R.J.5
-
55
-
-
84886930949
-
Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice
-
Kim, K., Hahm, E., Li, J., Holbrook, L. M., Sasikumar, P., Stanley, R. G., Ushio-Fukai, M., Gibbins, J. M., and Cho, J. (2013) Platelet protein disulfide isomerase is required for thrombus formation but not for hemostasis in mice. Blood 122, 1052-1061
-
(2013)
Blood
, vol.122
, pp. 1052-1061
-
-
Kim, K.1
Hahm, E.2
Li, J.3
Holbrook, L.M.4
Sasikumar, P.5
Stanley, R.G.6
Ushio-Fukai, M.7
Gibbins, J.M.8
Cho, J.9
-
56
-
-
0034844231
-
Processing of tumor necrosis factor by the membrane-bound TNF-β-converting enzyme, but not its truncated soluble form
-
Itai, T., Tanaka, M., and Nagata, S. (2001) Processing of tumor necrosis factor by the membrane-bound TNF-β-converting enzyme, but not its truncated soluble form. Eur. J. Biochem. 268, 2074-2082
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 2074-2082
-
-
Itai, T.1
Tanaka, M.2
Nagata, S.3
-
57
-
-
82955236074
-
Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1
-
Van Hauwermeiren, F., Van den Broucke, R. E., and Libert, C. (2011) Treatment of TNF mediated diseases by selective inhibition of soluble TNF or TNFR1. Cytokine Growth Factor Rev. 22, 311-319
-
(2011)
Cytokine Growth Factor Rev.
, vol.22
, pp. 311-319
-
-
Van Hauwermeiren, F.1
Van Den Broucke, R.E.2
Libert, C.3
-
58
-
-
84863845567
-
Antitumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo
-
Richards, F. M., Tape, C. J., Jodrell, D. I., and Murphy, G. (2012) Antitumour effects of a specific anti-ADAM17 antibody in an ovarian cancer model in vivo. PLoS ONE 7, e40597
-
(2012)
PLoS ONE
, vol.7
-
-
Richards, F.M.1
Tape, C.J.2
Jodrell, D.I.3
Murphy, G.4
|