Sulfhydryl regulation of L-selectin shedding: Phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes

Journal of Immunology

Volumn 164, Issue 8, 2000, Pages 4120-4129

  Bennett, Teresa A ^a   Edwards, Bruce S ^a   Sklar, Larry A ^a,b   Rogelj, Snezna ^a,c  

^a UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^b LOS ALAMOS NATIONAL LABORATORY   (United States)

^c NEW MEXICO INSTITUTE OF MINING AND TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARSENOSOBENZENE; BACITRACIN; L SELECTIN; PROTEIN DISULFIDE ISOMERASE; THIOL DERIVATIVE;

ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; LEUKOCYTE ACTIVATION; LYMPH NODE; LYMPHOCYTE TRANSFER; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 0034655128     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.164.8.4120     Document Type: Article

References (73)

1. Kishimoto, T. K., and R. Rothlein. 1994. Integrins, ICAMs, and selectins: role and regulation of adhesion molecules in neutrophil recruitment to inflammatory sites. Adv. Pharmacol. 25:117.
2. Butcher, E. C., and L. J. Picker. 1996. Lymphocyte homing and homeostasis. Science 272:60.
3. Tedder, T. F., D. A. Steeber, A. Chen, and P. Engel. 1995. The selectins: vascular adhesion molecules, FASEB J. 9:866.
4. Springer, T. A. 1995. Traffic signals on endothelium for lymphocyte recirculation and leukocyte emigration. Annu. Rev. Physiol. 57:827.
5. Smith, C. W., T. K. Kishimoto, O. Abbassi, B. Hughes, R. Rothlein, L. V. McIntire, E. Butcher, D. C. Anderson, and O. Abbassi. 1991. Chemotactic factors regulate lectin adhesion molecule-1 (LECAM-1)-dependent neutrophil adhesion to cytokine-stimulated endothelial cells in vitro. J. Clin. Invest. 87:609.
6. Bennett, T. A., C. M. Schammel, E. B. Lynam, D. A. Guyer, A. Mellors, B. Edwards, S. Rogelj, and L. A. Sklar. 1995. Evidence for a third component in neutrophil aggregation: potential roles of O-linked glycoproteins as L-selectin counter-structures. J. Leukocyte Biol. 58:510.
7. Guyer, D. A., K. L. Moore, E. B. Lynam, C. M. Schammel, S. Rogelj, R. P. McEver, and L. A. Sklar. 1996. P-selectin glycoprotein ligand-1 (PSGL-1) is a ligand for L-selectin in neutrophil aggregation. Blood 88:2415.
8. Bargatze, R. F., S. Kurk, E. C. Butcher, and M. A. Jutila. 1994. Neutrophils roll on adherent neutrophils bound to cytokine-induced endothelial cells via L-selectin on the rolling cells. J. Exp. Med. 180:1785.
9. + T cells. Immunology 87:186.
10. Malhotra, R., R. Priest, and M. I. Bird. 1996. Role for L-selectin in lipopolysaccharide-induced activation of neutrophils. Biochem. J. 320:589.
11. Ramamoorthy, C., S. R. Sharar, J. M. Harlan, T. F. Tedder, and R. K. Winn. 1996. Blocking L-selectin function attenuates reperfusion injury following hemorrhagic shock in rabbits. Am. J. Physiol. 271:H1871.
12. Bargatze, R. F., N. W. Wu, I. L. Weissman, and E. C. Butcher. 1987. High endothelial venule binding as a predictor of the dissemination of passaged murine lymphomas. J. Exp. Med. 166:1125.
13. Spertini, O., A. S. Freedman, M. P. Belvin, A. C. Penta, J. D. Griffin, and T. F. Tedder. 1991. Regulation of leukocyte adhesion molecule-1 (TQ1, Leu-8) expression and shedding by normal and malignant cells. Leukemia. 5:300.
14. Wang, L., J. J. Chen, B. B. Gelman, R. Konig, and M.W. Cloyd. 1999. A novel mechanism of CD4 lymphocyte depletion involves effects of HIV on resting lymphocytes: induction of lymph node homing and apoptosis upon secondary signaling through homing receptors. J. Immunol. 162:268.
15. Jutila, M. A. 1994. Function and regulation of leukocyte homing receptors. J. Leukocyte Biol. 55:133.
16. Kishimoto, T. K., M. A. Jutila, E. L. Berg, and E. C. Butcher. 1989. Neutrophil Mac-1 and MEL-14 adhesion proteins inversely regulated by chemotactic factors. Science 245:1238.
17. Tedder, T. F., D. A. Steeber, and P. Pizcueta. 1995. L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sites. J. Exp. Med. 181: 2259.
18. Bennett, T. A., E. B. Lynam, L. A. Sklar, and S. Rogelj. 1996. Hydroxamate-based metalloprotease inhibitor blocks shedding of L-selectin adhesion molecule from leukocytes: functional consequences for neutrophil aggregation. J. Immunol. 156:3093.
19. Miethke, T., C. Wahl, B. Holzmann, K. Heeg, and H. Wagner. 1993. Bacterial superantigens induce rapid and T cell receptor Vβ-selective down-regulation of L-selectin (gp90 Mel-14) in vivo. J. Immunol. 151:6777.
20. 2+, exocytosis of azurophilic granules, quantitative up-regulation of CD18, shedding of L-selectin, and actin polymerization. J. Leukocyte Biol. 56:625.
21. Palecanda, A., B. Walcheck, D. K. Bishop, and M. A. Jutila. 1992. Rapid activation-independent shedding of leukocyte L-selectin induced by cross-linking of the surface antigen. Eur. J. Immunol. 22:1279.
22. Steeber, D. A., N. E. Green, S. Sato, and T. F. Tedder. 1996. Lymphocyte migration in L-selectin-deficient mice. Altered subset migration and aging of the immune system. J. Immunol. 157:1096.
23. Steeber, D. A., N. E. Green, S. Sato, and T. F. Tedder. 1996. Humoral immune responses in L-selectin-deficient mice. J. Immunol. 157:4899.
24. Blann, A. D., P. A. Sanders, A. Herrick, and M. I. Jayson. 1996. Soluble L-selectin in the connective tissue diseases. Br. J. Haematol. 95:192.
25. Spertini, O., B. Schleiffenbaum, C. White-Owen, P. Ruiz, Jr., and T. F. Tedder. 1992. ELISA for quantitation of L-selectin shed from leukocytes in vivo. J. Immunol Methods 156:115.
26. Stoddart, J. H., Jr., R. R. Jasuja, M. A. Sikorski, U. H. von Andrian, and J. W. Mier. 1996. Protease-resistant L-selectin mutants: down-modulation by cross-linking but not cellular activation. J. Immunol. 157:5653.
27. Migaki, G. I., J. Kahn, and T. K. Kishimoto. 1995. Mutational analysis of the membrane-proximal cleavage site of L-selectin: relaxed sequence specificity surrounding the cleavage site. J. Exp. Med. 182:549.
28. Peschon, J. J., J. L. Slack, P. Reddy, K. L. Stocking, S. W. Sunnarborg, D. C. Lee, W. E. Russell, B. J. Castner, R. S. Johnson, J. N. Fitzner, et al. 1998. An essential role for ectodomain shedding in mammalian development. Science 282:1281.
29. Walcheck, B., J. Kahn, J. M. Fisher, B. B. Wang, R. S. Fisk, D. G. Payan, C. Feehan, R. Betageri, H. Darlak, A. F. Spatola. et al. 1996. Neutrophil rolling altered by inhibition of L-selectin shedding in vitro. Nature 380:720.
30. Allport, J. R., H. T. Ding, A. Ager, D. A. Steeber, T. F. Tedder, and F. W. Luscinskas. 1997. L-selectin shedding does not regulate human neutrophil attachment, rolling, or transmigration across human vascular endothelium in vitro. J. Immunol. 158:4365.
31. Preece, G., G. Murphy, and A. Ager. 1996. Metalloproteinase-mediated regulation of L-selectin levels on leucocytes. J. Biol. Chem. 271:11614.
32. Chen, A., P. Engel, and T. F. Tedder. 1995. Structural requirements regulate endoproteolytic release of the L-selectin (CD62L) adhesion receptor from the cell surface of leukocytes. J. Exp. Med. 182:519.
33. Kahn, J., B. Walcheck, G. I. Migaki, M. A. Jutila, and T. K. Kishimoto. 1998. Calmodulin regulates L-selectin adhesion molecule expression and function through a protease-dependent mechanism. Cell 92:809.
34. Webb, J. L. 1963. Enzyme and Metabolic Inhibitors, Vol. 3. Academic Press, New York, pp. 595-608.
35. Hoffman, R. D., and M. D. Lane. 1992. Iodophenylarsine oxide and arsenical affinity chromatography: new probes for dithiol proteins: application to tubulins and to components of the insulin receptor-glucose transporter signal transduction pathway. J. Biol. Chem. 267:14005.
36. Stockton, L. A., and R. H. S. Thompson. 1946. British anti-Lewisite. I. Arsenic derivatives of thiol proteins. Biochem. J. 40:529.
37. Hertel, C., S. J. Coulter, and J. P. Perkins. 1985. A comparison of catecholamine-induced internalization of β-adrenergic receptors and receptor-mediated endocytosis of epidermal growth factor in human astrocytoma cells: inhibition by phenylarsine oxide. J. Biol. Chem. 260:12547.
38. Liebl, B., H. Muckler, E. Doklea, F. X. Reichl, B. Fichtl, and W. Forth. 1995. Influence of glucose on the toxicity of oxophenylarsine in MDCK cells. Arch. Toxicol. 69:421.
39. Le Cabec, V., and I. Maridonneau-Parini. 1995. Complete and reversible inhibition of NADPH oxidase in human neutrophils by phenylarsine oxide at a step distal to membrane translocation of the enzyme subunits. J. Biol. Chem. 270: 2067.
40. Sugatani, J., M. E. Steinhelper, K. Saito, M. S. Olson, and D. J. Hanahan. 1987. Potential involvement of vicinal sulfhydryls in stimulus-induced rabbit platelet activation. J. Biol. Chem. 262:16995.
41. Flelcher, M. C., L. E. Samelson, and C. H. June. 1993. Complex effects of phenylarsine oxide in T cells: induction of tyrosine phosphorylation and calcium mobilization independent of CD45 expression. J. Biol. Chem. 268:23697.
42. Takahashi, A., P. J. Goldschmidt-Clermont,. E. S. Alnemri, T. Fernandes-Alnemri, K. Yoshizawa-Kumagaya, K. Nakajima, M. Sasada, G. G. Poirier, and W. C. Earnshaw. 1997. Inhibition of ICE-relaled proteases (caspases) and nuclear apoptosis by phenylarsine oxide. Exp. Cell Res. 231:123.
43. Ferrari, D. M., and H. D. Soling. 1999. The protein disulphide-isomerase family: unraveling a string of folds. Biochem. J. 339:1.
44. Wang, C. C. 1998. Protein disulfide isomerase assists protein folding as both an isomerase and a chaperone. Ann. NY Acad. Sci. 864:9.
45. Gilbert, H. F. 1997. Protein disulfide isomerase and assisted protein folding. J. Biol. Chem. 272:29399.
46. Thurau, A. M., U. Schylz, V. Wolf, N. Krug, and U. Schauer. 1996. Identification of eosinophils by flow cytometry. Cytometry 23:150.
47. 2-integrins. J. Leukocyte Biol. 60:356.
48. Edwards, B. S., M. S. Curry, E. A. Southon, A. S. Chong, and L. H. Graf, Jr. 1995. Evidence for a dithiol-activated signaling pathway in natural killer cell avidity regulation of leukocyte function antigen-1: structural requirements and relationship to phorbol ester-and CD16-triggered pathways. Blood 86:2288.
49. Hirota, K., M. Matsui, S. Iwata, A. Nishiyama, K. Mori, and J. Yodoi. 1997. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. USA 94:3633.
50. Jamba, L., B. Nehru, D. Medina, M. P. Bansal, and R. Sinha. 1996. Isolation and identification of selenium-labeled proteins in the mouse kidney. Anticancer Res. 16:1651.
51. Hillson, D. A., and R. B. Freedman RB. 1980. Resolution of protein disulphideisomerase and glutathione-insulin transhydrogenase activities by covalent chromatography. Biochem. J. 191:373.
52. Aposhian, H.V. 1982. Biological chelation: 2,3-dimercapto-propanesulfonic acid and meso-dimercaptosuccinic acid. Adv. Enzyme Regul. 20:301.
53. Aposhian, H. V., R. M. Maiorino, D. Gonzalez-Ramirez, M. Zuniga-Charles, Z. Xu, K. M. Hurlbut, P. Junco-Munoz, R. C. Dart, and M. M. Aposhian. 1995. Mobilization of heavy metals by newer, therapeutically useful chelating agents. Toxicology 97:23.
54. 2+ mobilization induced by collagen, but not thrombin or ADP, are inhibited by phenylarsine oxide. Br. J. Haematol. 88:830.
55. Yousefi, S., D. A. Green, K. Blaset, and H. U. Simon. 1994. Protein-tyrosine phosphorylation regulates apoptosis in human eosinophils and neutrophils. Proc. Natl. Acad. Sci. USA 91:10868.
56. Durden, D. L., H. Rosen, B. A. Michel, and J. A. Cooper. 1994. Protein tyrosine phosphatase inhibitors block myeloid signal transduction through the Fcγ receptor. Exp. Cell Res. 211:150.
57. Okuyama, M., J. Kambayashi, M. Sakon, and M. Monden. 1996. LFA-I/ICAM-3 mediates neutrophil homotypic aggregation under fluid shear stress. J. Cell. Biochem. 60:550.
58. 2-integrins mediate stable adhesion in collisional interactions between neutrophils and ICAM-1-expressing cells. J. Leukocyte Biol. 64:622.
59. Orlandi, P. A. 1997. Protein-disulfide isomerase-mediated reduction of the A subunit of cholera toxin in a human intestinal cell line. J. Biol. Chem. 272:4591.
60. Couet, J., S. de Bernard, H. Loosfelt, B. Saunier, E. Milgrom, and M. Misrahi. 1996. Cell surface protein disulfide-isomerase is involved in the shedding of human thyrotropin receptor ectodomain. Biochemistry 35:14800.
61. Kroning, H., T. Kahne, A. Ittenson, A. Franke, and S. Ansorge. 1994. Thiol-protein disulfide-oxidoreductase (proteindisulfide isomerase): a new plasma membrane constituent of mature human B lymphocytes. Scand. J. Immunol. 39:346.
62. Haribabu, B., D. A. Steeber, H. Ali, R. M. Richardson, R. Snyderman, and T. F. Tedder. 1997. Chemoattractant receptor-induced phosphorylation of L-selectin, J. Biol. Chem. 272:13961.
63. Ye, J. M., C. J. Key, and J. L. Wolfe. 1996. Covalent association of protein disulfide isomerase with recombinant human interleukin 2 in vitro. Biochem. Biophys. Res. Commun. 223:153.
64. Patel-King, R. S., S. E. Benashaki, A. Harrison, and S. M. King. 1996. Two functional thioredoxins containing redox-sensitive vicinal dithiols from the chlamydomonas outer dynein arm. J. Biol. Chem. 271:6283.
65. Horiuchi, R., K. Yamauchi, H. Hayashi, S. Koya, Y. Takeuchi, K. Kato, M. Kobayashi, and H. Takikawa. 1989. Purification and characterization of 55-kDa protein with 3,5,3′-triiodo-L-thyronine-binding activity and protein disulfide-isomerase activity from beef liver membrane. Eur. J. Biochem. 183:529.
66. Kalef, E., P. G. Walfish, and C. Gitler. 1993. Arsenical-based affinity chromatography of vicinal dithiol-containing proteins: purification of L1210 leukemia cytoplasmic proteins and the recombinant rat c-erbAβ1 T3 receptor. Anal. Biochem. 212:325.
67. Wetterau, J. R., K. A. Combs, L. R. McLean, S. N. Spinner, and L. P. Aggerbeck. 1991. Protein disulfide isomerase appears necessary to maintain the catalytically active structure of the microsomal triglyceride transfer protein. Biochemistry 30: 9728.
68. Terada, K., P. Manchikalapudi, R. Noiva, H. O. Jauregui, R. J. Stocken, and M. L. Schilsky. 1995. Secretion, surface localization, turnover, and steady state expression of protein disulfide isomerase in rat hepatocytes. J. Biol. Chem. 270: 20410.
69. Essex, D. W., K. Chen, and M. Swiatkowska, 1995. Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane. Blood 86:2168.
70. Krishna Rao, A. S., and R. E. Hausman. 1993. cDNA for R-cognin: homology with a multifunctional protein. Proc. Natl. Acad. Sci. USA 90:2950.
71. Huang, E. M., T. C. Detwiler, Y. Milev, and D. W. Essex. 1997. Thiol-disulfide isomerization in thrombospondin: effects of conformation and protein disulfide isomerase. Blood 89:3205.
72. Bassuk, J. A., C. Capodici, and R. A. Berg. 1990. Protein disulphide isomerase from human peripheral blood neutrophils. J. Cell. Physiol. 144:280.
73. Kim, J., and S. P. Mayfield. 1997. Protein disulfide isomerase as a regulator of chloroplast translational activation. Science 278:1954.