메뉴 건너뛰기




Volumn 23, Issue 10, 2015, Pages 2118-2122

Association of the fat mass and obesity-associated gene risk allele, rs9939609A, and reward-related brain structures

Author keywords

[No Author keywords available]

Indexed keywords

AGE; AGED; ALLELE; AMYGDALOID NUCLEUS; ARTICLE; BODY MASS; BRAIN SIZE; CAUDATE NUCLEUS; CONTROLLED STUDY; DUTCHMAN; FEMALE; GENDER; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; GLOBUS PALLIDUS; GRAY MATTER; HIPPOCAMPUS; HUMAN; LINEAR REGRESSION ANALYSIS; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEUS ACCUMBENS; PUTAMEN; REWARD; SINGLE NUCLEOTIDE POLYMORPHISM; THALAMUS; WHITE MATTER; BRAIN; COMPLICATION; DOUBLE BLIND PROCEDURE; GENETICS; OBESITY; PATHOLOGY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; VERY ELDERLY;

EID: 84942683847     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.21191     Document Type: Article
Times cited : (17)

References (40)
  • 1
    • 34248594090 scopus 로고    scopus 로고
    • A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity
    • Frayling TM, Timpson NJ, Weedon MN, et al., A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. Science 2007; 316: 889-894.
    • (2007) Science , vol.316 , pp. 889-894
    • Frayling, T.M.1    Timpson, N.J.2    Weedon, M.N.3
  • 2
    • 34249777814 scopus 로고    scopus 로고
    • Variation in FTO contributes to childhood obesity and severe adult obesity
    • Dina C, Meyre D, Gallina S, et al., Variation in FTO contributes to childhood obesity and severe adult obesity. Nat Genet 2007; 39: 724-726.
    • (2007) Nat Genet , vol.39 , pp. 724-726
    • Dina, C.1    Meyre, D.2    Gallina, S.3
  • 3
    • 41749090524 scopus 로고    scopus 로고
    • Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants
    • Hinney A, Nguyen TT, Scherag A, et al., Genome wide association (GWA) study for early onset extreme obesity supports the role of fat mass and obesity associated gene (FTO) variants. PLoS One 2007; 2: e1361.
    • (2007) PLoS One , vol.2 , pp. e1361
    • Hinney, A.1    Nguyen, T.T.2    Scherag, A.3
  • 4
    • 34547625955 scopus 로고    scopus 로고
    • Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits
    • Scuteri A, Sanna S, Chen WM, et al., Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits. PLoS Genet 2007; 3: e115.
    • (2007) PLoS Genet , vol.3 , pp. e115
    • Scuteri, A.1    Sanna, S.2    Chen, W.M.3
  • 5
    • 36749041363 scopus 로고    scopus 로고
    • The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase
    • Gerken T, Girard CA, Tung YC, et al., The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science 2007; 318: 1469-1472.
    • (2007) Science , vol.318 , pp. 1469-1472
    • Gerken, T.1    Girard, C.A.2    Tung, Y.C.3
  • 6
    • 84908637530 scopus 로고    scopus 로고
    • Brief communication: The fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults
    • Benedict C, Axelsson T, Soderberg S, et al., Brief communication: the fat mass and obesity-associated gene (FTO) is linked to higher plasma levels of the hunger hormone ghrelin and lower serum levels of the satiety hormone leptin in older adults. Diabetes 2014; 63: 3955-3859.
    • (2014) Diabetes , vol.63 , pp. 3955-3859
    • Benedict, C.1    Axelsson, T.2    Soderberg, S.3
  • 7
    • 84881257670 scopus 로고    scopus 로고
    • A link between FTO, ghrelin, and impaired brain food-cue responsivity
    • Karra E, O'Daly OG, Choudhury AI, et al., A link between FTO, ghrelin, and impaired brain food-cue responsivity. J Clin Invest 2013; 123: 3539-3551.
    • (2013) J Clin Invest , vol.123 , pp. 3539-3551
    • Karra, E.1    O'Daly, O.G.2    Choudhury, A.I.3
  • 8
    • 84897855294 scopus 로고    scopus 로고
    • Obesity-associated variants within FTO form long-range functional connections with IRX3
    • Smemo S, Tena JJ, Kim KH, et al., Obesity-associated variants within FTO form long-range functional connections with IRX3. Nature 2014; 507: 371-375.
    • (2014) Nature , vol.507 , pp. 371-375
    • Smemo, S.1    Tena, J.J.2    Kim, K.H.3
  • 9
    • 70350647201 scopus 로고    scopus 로고
    • Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO
    • den HM, Westerterp-Plantenga MS, Bouwman FG, et al., Postprandial responses in hunger and satiety are associated with the rs9939609 single nucleotide polymorphism in FTO. Am J Clin Nutr 2009; 90: 1426-1432.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1426-1432
    • Den, H.M.1    Westerterp-Plantenga, M.S.2    Bouwman, F.G.3
  • 10
    • 67649852402 scopus 로고    scopus 로고
    • Variation in the FTO gene influences food intake but not energy expenditure
    • Haupt A, Thamer C, Staiger H, et al., Variation in the FTO gene influences food intake but not energy expenditure. Exp Clin Endocrinol Diabet 2009; 117: 194-197.
    • (2009) Exp Clin Endocrinol Diabet , vol.117 , pp. 194-197
    • Haupt, A.1    Thamer, C.2    Staiger, H.3
  • 12
    • 84914107948 scopus 로고    scopus 로고
    • FTO genetic variants, dietary intake and body mass index: Insights from 177,330 individuals
    • Qi Q, Kilpelainen TO, Downer MK, et al., FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals. Hum Mol Genet 2014; 23: 6961-6972.
    • (2014) Hum Mol Genet , vol.23 , pp. 6961-6972
    • Qi, Q.1    Kilpelainen, T.O.2    Downer, M.K.3
  • 13
    • 84905924410 scopus 로고    scopus 로고
    • Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese Caucasian adults
    • Harbron J, van der Merwe L, Zaahl MG, Kotze MJ, Senekal M., Fat mass and obesity-associated (FTO) gene polymorphisms are associated with physical activity, food intake, eating behaviors, psychological health, and modeled change in body mass index in overweight/obese Caucasian adults. Nutrients 2014; 6: 3130-3152.
    • (2014) Nutrients , vol.6 , pp. 3130-3152
    • Harbron, J.1    Van Der Merwe, L.2    Zaahl, M.G.3    Kotze, M.J.4    Senekal, M.5
  • 14
    • 72749115949 scopus 로고    scopus 로고
    • The FTO gene rs9939609 obesity-risk allele and loss of control over eating
    • Tanofsky-Kraff M, Han JC, Anandalingam K, et al., The FTO gene rs9939609 obesity-risk allele and loss of control over eating. Am J Clin Nutr 2009; 90: 1483-1488.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1483-1488
    • Tanofsky-Kraff, M.1    Han, J.C.2    Anandalingam, K.3
  • 15
    • 84869102944 scopus 로고    scopus 로고
    • FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children
    • Velders FP, De Wit JE, Jansen PW, et al., FTO at rs9939609, food responsiveness, emotional control and symptoms of ADHD in preschool children. PLoS One 2012; 7: e49131.
    • (2012) PLoS One , vol.7 , pp. e49131
    • Velders, F.P.1    De Wit, J.E.2    Jansen, P.W.3
  • 16
    • 84903280081 scopus 로고    scopus 로고
    • Body mass index-related regional gray and white matter volume reductions in first-episode mania patients
    • Bond DJ, Ha TH, Lang DJ, et al., Body mass index-related regional gray and white matter volume reductions in first-episode mania patients. Biol Psychiatry 2014; 76: 138-145.
    • (2014) Biol Psychiatry , vol.76 , pp. 138-145
    • Bond, D.J.1    Ha, T.H.2    Lang, D.J.3
  • 17
    • 77952340870 scopus 로고    scopus 로고
    • A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
    • Ho AJ, Stein JL, Hua X, et al., A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci USA 2010; 107: 8404-8409.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8404-8409
    • Ho, A.J.1    Stein, J.L.2    Hua, X.3
  • 18
    • 79959649105 scopus 로고    scopus 로고
    • Disinhibited eating in obese adolescents is associated with orbitofrontal volume reductions and executive dysfunction
    • Maayan L, Hoogendoorn C, Sweat V, Convit A., Disinhibited eating in obese adolescents is associated with orbitofrontal volume reductions and executive dysfunction. Obesity 2011; 19: 1382-1387.
    • (2011) Obesity , vol.19 , pp. 1382-1387
    • Maayan, L.1    Hoogendoorn, C.2    Sweat, V.3    Convit, A.4
  • 19
    • 79954490068 scopus 로고    scopus 로고
    • Sex-dependent influences of obesity on cerebral white matter investigated by diffusion-tensor imaging
    • Mueller K, Anwander A, Moller HE, et al., Sex-dependent influences of obesity on cerebral white matter investigated by diffusion-tensor imaging. PLoS One 2011; 6: e18544.
    • (2011) PLoS One , vol.6 , pp. e18544
    • Mueller, K.1    Anwander, A.2    Moller, H.E.3
  • 20
    • 79955538364 scopus 로고    scopus 로고
    • Body weight and the reward system: The volume of the right amygdala may be associated with body mass index in young overweight men
    • Orsi G, Perlaki G, Kovacs N, et al., Body weight and the reward system: the volume of the right amygdala may be associated with body mass index in young overweight men. Brain Imaging Behav 2011; 5: 149-157.
    • (2011) Brain Imaging Behav , vol.5 , pp. 149-157
    • Orsi, G.1    Perlaki, G.2    Kovacs, N.3
  • 21
    • 33745456661 scopus 로고    scopus 로고
    • Brain abnormalities in human obesity: A voxel-based morphometric study
    • Pannacciulli N, Del PA, Chen K, et al., Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage 2006; 31: 1419-1425.
    • (2006) Neuroimage , vol.31 , pp. 1419-1425
    • Pannacciulli, N.1    Del, P.A.2    Chen, K.3
  • 23
    • 77953826124 scopus 로고    scopus 로고
    • Structural brain differences and cognitive functioning related to body mass index in older females
    • Walther K, Birdsill AC, Glisky EL, Ryan L., Structural brain differences and cognitive functioning related to body mass index in older females. Hum Brain Mapp 2010; 31: 1052-1064.
    • (2010) Hum Brain Mapp , vol.31 , pp. 1052-1064
    • Walther, K.1    Birdsill, A.C.2    Glisky, E.L.3    Ryan, L.4
  • 24
    • 79956301147 scopus 로고    scopus 로고
    • Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease
    • Widya RL, de RA, Trompet S, et al., Increased amygdalar and hippocampal volumes in elderly obese individuals with or at risk of cardiovascular disease. Am J Clin Nutr 2011; 93: 1190-1195.
    • (2011) Am J Clin Nutr , vol.93 , pp. 1190-1195
    • Widya, R.L.1    De, R.A.2    Trompet, S.3
  • 25
    • 84860707186 scopus 로고    scopus 로고
    • Relation of regional gray and white matter volumes to current BMI and future increases in BMI: A prospective MRI study
    • Yokum S, Ng J, Stice E., Relation of regional gray and white matter volumes to current BMI and future increases in BMI: a prospective MRI study. Int J Obes (Lond) 2012; 36: 656-664.
    • (2012) Int J Obes (Lond) , vol.36 , pp. 656-664
    • Yokum, S.1    Ng, J.2    Stice, E.3
  • 26
    • 0032707276 scopus 로고    scopus 로고
    • The design of a prospective study of Pravastatin in the elderly at risk (PROSPER). PROSPER Study Group. PROspective Study of Pravastatin in the Elderly at Risk
    • Shepherd J, Blauw GJ, Murphy MB, et al., The design of a prospective study of Pravastatin in the elderly at risk (PROSPER). PROSPER Study Group. PROspective Study of Pravastatin in the Elderly at Risk. Am J Cardiol 1999; 84: 1192-1197.
    • (1999) Am J Cardiol , vol.84 , pp. 1192-1197
    • Shepherd, J.1    Blauw, G.J.2    Murphy, M.B.3
  • 27
    • 0016823810 scopus 로고
    • Mini-mental state: A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR., Mini-mental state: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975; 12: 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 28
    • 7044260964 scopus 로고    scopus 로고
    • Advances in functional and structural MR image analysis and implementation as FSL
    • Smith SM, Jenkinson M, Woolrich MW, et al., Advances in functional and structural MR image analysis and implementation as FSL. Neuroimage 2004; 23: S208-S219.
    • (2004) Neuroimage , vol.23 , pp. S208-S219
    • Smith, S.M.1    Jenkinson, M.2    Woolrich, M.W.3
  • 29
    • 65549131149 scopus 로고    scopus 로고
    • Bayesian analysis of neuroimaging data in FSL
    • Woolrich MW, Jbabdi S, Patenaude B, et al., Bayesian analysis of neuroimaging data in FSL. Neuroimage 2009; 45: S173-S186.
    • (2009) Neuroimage , vol.45 , pp. S173-S186
    • Woolrich, M.W.1    Jbabdi, S.2    Patenaude, B.3
  • 30
    • 84949114805 scopus 로고    scopus 로고
    • Gender-specific genetic associations of polymorphisms in ACE, AKR1C2, FTO and MMP2 with weight gain over a 10-year period
    • Bouwman FG, Boer JM, Imholz S, et al., Gender-specific genetic associations of polymorphisms in ACE, AKR1C2, FTO and MMP2 with weight gain over a 10-year period. Genes Nutr 2014; 9: 434.
    • (2014) Genes Nutr , vol.9 , pp. 434
    • Bouwman, F.G.1    Boer, J.M.2    Imholz, S.3
  • 31
    • 42249083837 scopus 로고    scopus 로고
    • The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain
    • Fredriksson R, Hagglund M, Olszewski PK, et al., The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain. Endocrinology 2008; 149: 2062-2071.
    • (2008) Endocrinology , vol.149 , pp. 2062-2071
    • Fredriksson, R.1    Hagglund, M.2    Olszewski, P.K.3
  • 32
    • 82355194591 scopus 로고    scopus 로고
    • FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting
    • McTaggart JS, Lee S, Iberl M, Church C, Cox RD, Ashcroft FM., FTO is expressed in neurones throughout the brain and its expression is unaltered by fasting. PLoS One 2011; 6: e27968.
    • (2011) PLoS One , vol.6 , pp. e27968
    • McTaggart, J.S.1    Lee, S.2    Iberl, M.3    Church, C.4    Cox, R.D.5    Ashcroft, F.M.6
  • 34
    • 84877091458 scopus 로고    scopus 로고
    • Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus
    • Vujovic P, Stamenkovic S, Jasnic N, et al., Fasting induced cytoplasmic Fto expression in some neurons of rat hypothalamus. PLoS One 2013; 8: e63694.
    • (2013) PLoS One , vol.8 , pp. e63694
    • Vujovic, P.1    Stamenkovic, S.2    Jasnic, N.3
  • 35
    • 84887989544 scopus 로고    scopus 로고
    • Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: Effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors
    • Nunes EJ, Randall PA, Podurgiel S, Correa M, Salamone JD., Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors. Neurosci Biobehav Rev 2013; 37: 2015-2025.
    • (2013) Neurosci Biobehav Rev , vol.37 , pp. 2015-2025
    • Nunes, E.J.1    Randall, P.A.2    Podurgiel, S.3    Correa, M.4    Salamone, J.D.5
  • 36
    • 84868265622 scopus 로고    scopus 로고
    • Contribution of the mesolimbic dopamine system in mediating the effects of leptin and ghrelin on feeding
    • van Zessen R, van der Plasse G, Adan RA., Contribution of the mesolimbic dopamine system in mediating the effects of leptin and ghrelin on feeding. Proc Nutr Soc 2012; 71: 435-445.
    • (2012) Proc Nutr Soc , vol.71 , pp. 435-445
    • Van Zessen, R.1    Van Der Plasse, G.2    Adan, R.A.3
  • 37
    • 0028237718 scopus 로고
    • The nucleus accumbens as a complex of functionally distinct neuronal ensembles: An integration of behavioural, electrophysiological and anatomical data
    • Pennartz CM, Groenewegen HJ., Lopes da Silva FH. The nucleus accumbens as a complex of functionally distinct neuronal ensembles: an integration of behavioural, electrophysiological and anatomical data. Prog Neurobiol 1994; 42: 719-761.
    • (1994) Prog Neurobiol , vol.42 , pp. 719-761
    • Pennartz, C.M.1    Groenewegen, H.J.2    Lopes Da Silva, F.H.3
  • 38
    • 84880916638 scopus 로고    scopus 로고
    • The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry
    • Hess ME, Hess S, Meyer KD, et al., The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry. Nat Neurosci 2013; 16: 1042-1048.
    • (2013) Nat Neurosci , vol.16 , pp. 1042-1048
    • Hess, M.E.1    Hess, S.2    Meyer, K.D.3
  • 39
    • 84873415004 scopus 로고    scopus 로고
    • FTO, obesity and the adolescent brain
    • Melka MG, Gillis J, Bernard M, et al., FTO, obesity and the adolescent brain. Hum Mol Genet 2013; 22: 1050-1058.
    • (2013) Hum Mol Genet , vol.22 , pp. 1050-1058
    • Melka, M.G.1    Gillis, J.2    Bernard, M.3
  • 40
    • 84883620674 scopus 로고    scopus 로고
    • Body mass index, but not FTO genotype or major depressive disorder, influences brain structure
    • Cole JH, Boyle CP, Simmons A, et al., Body mass index, but not FTO genotype or major depressive disorder, influences brain structure. Neuroscience 2013; 252: 109-117.
    • (2013) Neuroscience , vol.252 , pp. 109-117
    • Cole, J.H.1    Boyle, C.P.2    Simmons, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.