메뉴 건너뛰기




Volumn 27, Issue 4, 2015, Pages 357-363

Endoplasmic reticulum aminopeptidase 1 and rheumatic disease: Functional variation

Author keywords

Ankylosing spondylitis; Endoplasmic reticulum aminopeptidase 1; Human leukocyte antigen B27; Rheumatic disease

Indexed keywords

AMINOPEPTIDASE; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; HLA B27 ANTIGEN; UNCLASSIFIED DRUG; ERAP1 PROTEIN, HUMAN; HLA ANTIGEN CLASS 1; MINOR HISTOCOMPATIBILITY ANTIGEN;

EID: 84942616583     PISSN: 10408711     EISSN: 15316963     Source Type: Journal    
DOI: 10.1097/BOR.0000000000000188     Document Type: Review
Times cited : (24)

References (35)
  • 1
    • 84890047365 scopus 로고    scopus 로고
    • Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum
    • Shastri N, Nagarajan N, Lind KC, et al. Monitoring peptide processing for MHC class I molecules in the endoplasmic reticulum. Curr Opin Immunol 2014;26:123-127.
    • (2014) Curr Opin Immunol , vol.26 , pp. 123-127
    • Shastri, N.1    Nagarajan, N.2    Lind, K.C.3
  • 4
    • 84873091770 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B∗51 and ERAP1
    • Kirino Y, Bertsias G, Ishigatsubo Y, et al. Genome-wide association analysis identifies new susceptibility loci for Behcet's disease and epistasis between HLA-B∗51 and ERAP1. Nat Genet 2013;45:202-207.
    • (2013) Nat Genet , vol.45 , pp. 202-207
    • Kirino, Y.1    Bertsias, G.2    Ishigatsubo, Y.3
  • 5
    • 0031051852 scopus 로고    scopus 로고
    • Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome
    • Hughes EA, Hammond C, Cresswell P. Misfolded major histocompatibility complex class I heavy chains are translocated into the cytoplasm and degraded by the proteasome. Proc Natl Acad Sci U S A 1997;94:1896-1901.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 1896-1901
    • Hughes, E.A.1    Hammond, C.2    Cresswell, P.3
  • 6
    • 84883483728 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidases: Biochemistry, physiology and pathology
    • Hattori A, Tsujimoto M. Endoplasmic reticulum aminopeptidases: biochemistry, physiology and pathology. J Biochem 2013;154:219-228.
    • (2013) J Biochem , vol.154 , pp. 219-228
    • Hattori, A.1    Tsujimoto, M.2
  • 7
    • 67650465638 scopus 로고    scopus 로고
    • IRAP identifies an endosomal compartment required for MHC class I cross-presentation
    • Saveanu L, Carroll O, Weimershaus M, et al. IRAP identifies an endosomal compartment required for MHC class I cross-presentation. Science 2009;325:213-217.
    • (2009) Science , vol.325 , pp. 213-217
    • Saveanu, L.1    Carroll, O.2    Weimershaus, M.3
  • 8
    • 22744438096 scopus 로고    scopus 로고
    • The oxytocinase subfamily of M1 aminopeptidases
    • Tsujimoto M, Hattori A. The oxytocinase subfamily of M1 aminopeptidases. Biochim Biophys Acta 2005;1751:9-18.
    • (2005) Biochim Biophys Acta , vol.1751 , pp. 9-18
    • Tsujimoto, M.1    Hattori, A.2
  • 9
    • 79956348710 scopus 로고    scopus 로고
    • Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming
    • Kochan G, Krojer T, Harvey D, et al. Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming. Proc Natl Acad Sci U S A 2011;108:7745-7750.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 7745-7750
    • Kochan, G.1    Krojer, T.2    Harvey, D.3
  • 10
    • 0037015624 scopus 로고    scopus 로고
    • ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
    • Serwold T, Gonzalez F, Kim J, et al. ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature 2002;419:480-483.
    • (2002) Nature , vol.419 , pp. 480-483
    • Serwold, T.1    Gonzalez, F.2    Kim, J.3
  • 11
    • 29244461714 scopus 로고    scopus 로고
    • The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules
    • Hammer GE, Gonzalez F, Champsaur M, et al. The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules. Nat Immunol 2006;7:103-112.
    • (2006) Nat Immunol , vol.7 , pp. 103-112
    • Hammer, G.E.1    Gonzalez, F.2    Champsaur, M.3
  • 12
    • 0036884090 scopus 로고    scopus 로고
    • The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
    • York IA, Chang SC, Saric T, et al. The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol 2002;3:1177-1184.
    • (2002) Nat Immunol , vol.3 , pp. 1177-1184
    • York, I.A.1    Chang, S.C.2    Saric, T.3
  • 13
    • 22144442460 scopus 로고    scopus 로고
    • Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum
    • Saveanu L, Carroll O, Lindo V, et al. Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum. Nat Immunol 2005;6:689-697.
    • (2005) Nat Immunol , vol.6 , pp. 689-697
    • Saveanu, L.1    Carroll, O.2    Lindo, V.3
  • 14
    • 79951817611 scopus 로고    scopus 로고
    • Cutting edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme
    • Evnouchidou I, Kamal RP, Seregin SS, et al. Cutting edge: coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme. J Immunol 2011;186:1909-1913.
    • (2011) J Immunol , vol.186 , pp. 1909-1913
    • Evnouchidou, I.1    Kamal, R.P.2    Seregin, S.S.3
  • 15
    • 78449233933 scopus 로고    scopus 로고
    • Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation
    • Andres AM, Dennis MY, Kretzschmar WW, et al. Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. PLoS Genet 2010;6:e1001157.
    • (2010) PLoS Genet , vol.6 , pp. e1001157
    • Andres, A.M.1    Dennis, M.Y.2    Kretzschmar, W.W.3
  • 16
    • 80051949544 scopus 로고    scopus 로고
    • A common functional variant of endoplasmic reticulum aminopeptidase 2 (ERAP2) that reduces major histocompatibility complex class I expression is not associated with ankylosing spondylitis
    • Harvey D, Pointon JJ, Karaderi T, et al. A common functional variant of endoplasmic reticulum aminopeptidase 2 (ERAP2) that reduces major histocompatibility complex class I expression is not associated with ankylosing spondylitis. Rheumatology (Oxford) 2011;50:1720-1721.
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 1720-1721
    • Harvey, D.1    Pointon, J.J.2    Karaderi, T.3
  • 17
    • 84911388736 scopus 로고    scopus 로고
    • A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy
    • Kuiper JJ, Van Setten J, Ripke S, et al. A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy. Hum Mol Genet 2014;23:6081-6087.
    • (2014) Hum Mol Genet , vol.23 , pp. 6081-6087
    • Kuiper, J.J.1    Van Setten, J.2    Ripke, S.3
  • 18
    • 33745125912 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance
    • York IA, Brehm MA, Zendzian S, et al. Endoplasmic reticulum aminopeptidase 1 (ERAP1) trims MHC class I-presented peptides in vivo and plays an important role in immunodominance. Proc Natl Acad Sci U S A 2006;103:9202-9207.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 9202-9207
    • York, I.A.1    Brehm, M.A.2    Zendzian, S.3
  • 19
    • 33645089946 scopus 로고    scopus 로고
    • In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules
    • Yan J, Parekh VV, Mendez-Fernandez Y, et al. In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules. J Exp Med 2006;203:647-659.
    • (2006) J Exp Med , vol.203 , pp. 647-659
    • Yan, J.1    Parekh, V.V.2    Mendez-Fernandez, Y.3
  • 20
    • 33846927019 scopus 로고    scopus 로고
    • The role of endoplasmic reticulumassociated aminopeptidase 1 in immunity to infection and in cross-presentation
    • Firat E, Saveanu L, Aichele P, et al. The role of endoplasmic reticulumassociated aminopeptidase 1 in immunity to infection and in cross-presentation. J Immunol 2007;178:2241-2248.
    • (2007) J Immunol , vol.178 , pp. 2241-2248
    • Firat, E.1    Saveanu, L.2    Aichele, P.3
  • 21
    • 28044456942 scopus 로고    scopus 로고
    • The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a 'molecular ruler' mechanism
    • Chang SC, Momburg F, Bhutani N, et al. The ER aminopeptidase, ERAP1, trims precursors to lengths of MHC class I peptides by a 'molecular ruler' mechanism. Proc Natl Acad Sci U S A 2005;102:17107-17112.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17107-17112
    • Chang, S.C.1    Momburg, F.2    Bhutani, N.3
  • 22
    • 77951900588 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells
    • Blanchard N, Kanaseki T, Escobar H, et al. Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J Immunol 2010;184:3033-3042.
    • (2010) J Immunol , vol.184 , pp. 3033-3042
    • Blanchard, N.1    Kanaseki, T.2    Escobar, H.3
  • 23
    • 84896269583 scopus 로고    scopus 로고
    • Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27
    • Chen L, Fischer R, Peng Y, et al. Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27. Arthritis Rheumatol 2014;66:284-294.
    • (2014) Arthritis Rheumatol , vol.66 , pp. 284-294
    • Chen, L.1    Fischer, R.2    Peng, Y.3
  • 24
    • 73249153202 scopus 로고    scopus 로고
    • From HLA-B27 to spondyloarthritis: A journey through the ER
    • Colbert RA, De Lay ML, Klenk EI, et al. From HLA-B27 to spondyloarthritis: a journey through the ER. Immunol Rev 2010;233:181-202.
    • (2010) Immunol Rev , vol.233 , pp. 181-202
    • Colbert, R.A.1    De Lay, M.L.2    Klenk, E.I.3
  • 25
    • 79960899377 scopus 로고    scopus 로고
    • Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
    • Evans DM, Spencer CC, Pointon JJ, et al. Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. Nat Genet 2011;43:761-767.
    • (2011) Nat Genet , vol.43 , pp. 761-767
    • Evans, D.M.1    Spencer, C.C.2    Pointon, J.J.3
  • 26
    • 70349991884 scopus 로고    scopus 로고
    • Investigating the genetic association between ERAP1 and ankylosing spondylitis
    • Harvey D, Pointon JJ, Evans DM, et al. Investigating the genetic association between ERAP1 and ankylosing spondylitis. Hum Mol Genet 2009;18:4204-4212.
    • (2009) Hum Mol Genet , vol.18 , pp. 4204-4212
    • Harvey, D.1    Pointon, J.J.2    Evans, D.M.3
  • 27
    • 84916890237 scopus 로고    scopus 로고
    • Functionally distinct ERAP1 allotype combinations distinguish individuals with ankylosing spondylitis
    • Reeves E, Colebatch-Bourn A, Elliott T, et al. Functionally distinct ERAP1 allotype combinations distinguish individuals with ankylosing spondylitis. Proc Natl Acad Sci U S A 2014;111:17594-17599.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 17594-17599
    • Reeves, E.1    Colebatch-Bourn, A.2    Elliott, T.3
  • 28
    • 84879663069 scopus 로고    scopus 로고
    • Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity
    • Reeves E, Edwards CJ, Elliott T, et al. Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity. J Immunol 2013;191:35-43.
    • (2013) J Immunol , vol.191 , pp. 35-43
    • Reeves, E.1    Edwards, C.J.2    Elliott, T.3
  • 29
    • 84856072195 scopus 로고    scopus 로고
    • The origin of proteasomeinhibitor resistant HLA class I peptidomes: A study with HLA-A∗68:01
    • Garcia-Medel N, Sanz-Bravo A, Barnea E, et al. The origin of proteasomeinhibitor resistant HLA class I peptidomes: a study with HLA-A∗68:01. Mol Cell Proteomics 2012;11:M111-011486-1-15.
    • (2012) Mol Cell Proteomics , vol.11
    • Garcia-Medel, N.1    Sanz-Bravo, A.2    Barnea, E.3
  • 30
    • 84929891993 scopus 로고    scopus 로고
    • ERAP1 gene expression is influenced by nonsynonymous polymorphisms associated with predisposition to spondyloarthritis
    • Epub ahead of print
    • Costantino F, Talpin A, Evnouchidou I, et al. ERAP1 gene expression is influenced by nonsynonymous polymorphisms associated with predisposition to spondyloarthritis. Arthritis Rheumatol 2015. [Epub ahead of print]
    • (2015) Arthritis Rheumatol
    • Costantino, F.1    Talpin, A.2    Evnouchidou, I.3
  • 31
    • 84857924158 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis
    • Haroon N, Tsui FW, Uchanska-Ziegler B, et al. Endoplasmic reticulum aminopeptidase 1 (ERAP1) exhibits functionally significant interaction with HLA-B27 and relates to subtype specificity in ankylosing spondylitis. Ann Rheum Dis 2012;71:589-595.
    • (2012) Ann Rheum Dis , vol.71 , pp. 589-595
    • Haroon, N.1    Tsui, F.W.2    Uchanska-Ziegler, B.3
  • 32
    • 84902180272 scopus 로고    scopus 로고
    • HLA-B27, but not HLA-B7, immunodominance to influenza is ERAP dependent
    • Akram A, Lin A, Gracey E, et al. HLA-B27, but not HLA-B7, immunodominance to influenza is ERAP dependent. J Immunol 2014;192:5520-5528.
    • (2014) J Immunol , vol.192 , pp. 5520-5528
    • Akram, A.1    Lin, A.2    Gracey, E.3
  • 33
    • 84899576357 scopus 로고    scopus 로고
    • TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages
    • Goto Y, Ogawa K, Nakamura TJ, et al. TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages. J Immunol 2014;192:4443-4452
    • (2014) J Immunol , vol.192 , pp. 4443-4452
    • Goto, Y.1    Ogawa, K.2    Nakamura, T.J.3
  • 34
    • 79958709420 scopus 로고    scopus 로고
    • Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma
    • Goto Y, Ogawa K, Hattori A, et al. Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-gamma. J Biol Chem 2011;286:21906-21914.
    • (2011) J Biol Chem , vol.286 , pp. 21906-21914
    • Goto, Y.1    Ogawa, K.2    Hattori, A.3
  • 35
    • 84924271854 scopus 로고    scopus 로고
    • Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages
    • Epub ahead of print
    • Goto Y, Ogawa K, Nakamura TJ, et al. Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages. J Biochem 2015. [Epub ahead of print]
    • (2015) J Biochem
    • Goto, Y.1    Ogawa, K.2    Nakamura, T.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.