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Volumn 157, Issue 6, 2015, Pages 439-449

Substrate-dependent nitric oxide synthesis by secreted endoplasmic reticulum aminopeptidase 1 in macrophages

Author keywords

Aminopeptidase; Arginine; Lipopolysaccharide; Macrophage; Nitric oxide

Indexed keywords

AMASTATIN; AMINOPEPTIDASE; ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE; UNCLASSIFIED DRUG; ERAP1 PROTEIN, MOUSE;

EID: 84924271854     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvv001     Document Type: Article
Times cited : (18)

References (60)
  • 1
    • 0027479013 scopus 로고
    • Aminopeptidases: Structure and function
    • Taylor, A. (1993) Aminopeptidases: structure and function. FASEB J. 7, 290-298
    • (1993) FASEB J. , vol.7 , pp. 290-298
    • Taylor, A.1
  • 2
    • 22744438096 scopus 로고    scopus 로고
    • The oxytocinase subfamily of M1 aminopeptidases
    • Tsujimoto, M. and Hattori, A. (2005) The oxytocinase subfamily of M1 aminopeptidases. Biochim. Biophys. Acta. 1751, 9-18
    • (2005) Biochim. Biophys. Acta. , vol.1751 , pp. 9-18
    • Tsujimoto, M.1    Hattori, A.2
  • 3
    • 0033958063 scopus 로고    scopus 로고
    • Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells
    • Matsumoto, H., Rogi, T., Yamashiro, K., Kodama, S., Tsuruoka, N., Hattori, A., Takio, K., Mizutani, S., and Tsujimoto, M. (2000) Characterization of a recombinant soluble form of human placental leucine aminopeptidase/oxytocinase expressed in Chinese hamster ovary cells. Eur. J. Biochem. 267, 46-52
    • (2000) Eur. J. Biochem. , vol.267 , pp. 46-52
    • Matsumoto, H.1    Rogi, T.2    Yamashiro, K.3    Kodama, S.4    Tsuruoka, N.5    Hattori, A.6    Takio, K.7    Mizutani, S.8    Tsujimoto, M.9
  • 7
    • 33846117473 scopus 로고    scopus 로고
    • Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat
    • Stragier, B., Demaegdt, H., De Bundel, D., Smolders, I., Sarre, S., Vauquelin, G., Ebinger, G., Michotte, Y., and Vanderheyden, P. (2007) Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat. Brain Res. 1131, 97-105
    • (2007) Brain Res. , vol.1131 , pp. 97-105
    • Stragier, B.1    Demaegdt, H.2    De Bundel, D.3    Smolders, I.4    Sarre, S.5    Vauquelin, G.6    Ebinger, G.7    Michotte, Y.8    Vanderheyden, P.9
  • 8
    • 33746407274 scopus 로고    scopus 로고
    • Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats
    • Stragier, B., Clinckers, R., Meurs, A., De Bundel, D., Sarre, S., Ebinger, G., Michotte, Y., and Smolders, I. (2006) Involvement of the somatostatin-2 receptor in the anti-convulsant effect of angiotensin IV against pilocarpine-induced limbic seizures in rats. J. Neurochem. 98, 1100-1113
    • (2006) J. Neurochem. , vol.98 , pp. 1100-1113
    • Stragier, B.1    Clinckers, R.2    Meurs, A.3    De Bundel, D.4    Sarre, S.5    Ebinger, G.6    Michotte, Y.7    Smolders, I.8
  • 10
    • 0029859206 scopus 로고    scopus 로고
    • Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: Predominant role of angiotensin III in the control of vasopressin release
    • Zini, S., Fournie-Zaluski, M. C., Chauvel, E., Roques, B. P., Corvol, P., and Llorens-Cortes, C. (1996) Identification of metabolic pathways of brain angiotensin II and III using specific aminopeptidase inhibitors: predominant role of angiotensin III in the control of vasopressin release. Proc. Natl. Acad. Sci. USA. 93, 11968-11973
    • (1996) Proc. Natl. Acad. Sci. USA. , vol.93 , pp. 11968-11973
    • Zini, S.1    Fournie-Zaluski, M.C.2    Chauvel, E.3    Roques, B.P.4    Corvol, P.5    Llorens-Cortes, C.6
  • 11
    • 0037409920 scopus 로고    scopus 로고
    • Neuron-specific aminopeptidase and puromycin-sensitive aminopeptidase in rat brain development
    • Hui, M. and Hui, K. S. (2003) Neuron-specific aminopeptidase and puromycin-sensitive aminopeptidase in rat brain development. Neurochem. Res. 28, 855-860
    • (2003) Neurochem. Res. , vol.28 , pp. 855-860
    • Hui, M.1    Hui, K.S.2
  • 12
    • 0020286158 scopus 로고
    • Effects of protease inhibitors on ingestion and digestion of soluble antigenantibody complexes by macrophages
    • Nihira, S. and Koyama, J. (1982) Effects of protease inhibitors on ingestion and digestion of soluble antigenantibody complexes by macrophages. J. Biochem. 92, 1567-1576
    • (1982) J. Biochem. , vol.92 , pp. 1567-1576
    • Nihira, S.1    Koyama, J.2
  • 13
    • 0020636015 scopus 로고
    • Analysis of proteases involved in phagocytic activity of macrophages through the use of various amino acid esters
    • Nihira, S. and Koyama, J. (1983) Analysis of proteases involved in phagocytic activity of macrophages through the use of various amino acid esters. J. Biochem. 94, 565-573
    • (1983) J. Biochem. , vol.94 , pp. 565-573
    • Nihira, S.1    Koyama, J.2
  • 14
    • 84883483728 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidases: Biochemistry, physiology and pathology
    • Hattori, A. and Tsujimoto, M. (2013) Endoplasmic reticulum aminopeptidases: biochemistry, physiology and pathology. J. Biochem. 154, 219-228
    • (2013) J. Biochem. , vol.154 , pp. 219-228
    • Hattori, A.1    Tsujimoto, M.2
  • 15
    • 0033056047 scopus 로고    scopus 로고
    • Molecular cloning of adipocytederived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase
    • Hattori, A., Matsumoto, H., Mizutani, S., and Tsujimoto, M. (1999) Molecular cloning of adipocytederived leucine aminopeptidase highly related to placental leucine aminopeptidase/oxytocinase. J. Biochem. 125, 931-938
    • (1999) J. Biochem. , vol.125 , pp. 931-938
    • Hattori, A.1    Matsumoto, H.2    Mizutani, S.3    Tsujimoto, M.4
  • 17
    • 0037015624 scopus 로고    scopus 로고
    • ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum
    • Serwold, T., Gonzalez, F., Kim, J., Jacob, R., and Shastri, N. (2002) ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum. Nature 419, 480-483
    • (2002) Nature , vol.419 , pp. 480-483
    • Serwold, T.1    Gonzalez, F.2    Kim, J.3    Jacob, R.4    Shastri, N.5
  • 19
    • 84859449946 scopus 로고    scopus 로고
    • Exon 10 coding sequence is important for endoplasmic reticulum retention of endoplasmic reticulum aminopeptidase 1
    • Hattori, A., Goto, Y., and Tsujimoto, M. (2012) Exon 10 coding sequence is important for endoplasmic reticulum retention of endoplasmic reticulum aminopeptidase 1. Biol. Pharm. Bull. 35, 601-605
    • (2012) Biol. Pharm. Bull. , vol.35 , pp. 601-605
    • Hattori, A.1    Goto, Y.2    Tsujimoto, M.3
  • 21
    • 84864376114 scopus 로고    scopus 로고
    • Role of endoplasmic reticulum aminopeptidases in health and disease: From infection to cancer
    • Cifaldi, L., Romania, P., Lorenzi, S., Locatelli, F., and Fruci, D. (2012) Role of endoplasmic reticulum aminopeptidases in health and disease: from infection to cancer. Int. J. Mol. Sci. 13, 8338-8352
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 8338-8352
    • Cifaldi, L.1    Romania, P.2    Lorenzi, S.3    Locatelli, F.4    Fruci, D.5
  • 22
    • 16644386079 scopus 로고    scopus 로고
    • Role of aminopeptidase in angiogenesis
    • Sato, Y. (2004) Role of aminopeptidase in angiogenesis. Biol. Pharm. Bull. 27, 772-776
    • (2004) Biol. Pharm. Bull. , vol.27 , pp. 772-776
    • Sato, Y.1
  • 23
    • 77955332608 scopus 로고    scopus 로고
    • Endoplasmic reticulum aminopeptidases: Biology and pathogenic potential
    • Haroon, N. and Inman, R. D. (2010) Endoplasmic reticulum aminopeptidases: biology and pathogenic potential. Nat. Rev. Rheumatol. 6, 461-467
    • (2010) Nat. Rev. Rheumatol. , vol.6 , pp. 461-467
    • Haroon, N.1    Inman, R.D.2
  • 24
    • 56949107069 scopus 로고    scopus 로고
    • The quality control of MHC class I peptide loading
    • Wearsch, P. A. and Cresswell, P. (2008) The quality control of MHC class I peptide loading. Curr. Opin. Cell Biol. 20, 624-631
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 624-631
    • Wearsch, P.A.1    Cresswell, P.2
  • 25
    • 0036565887 scopus 로고    scopus 로고
    • A mouse orthologue of puromycin-insensitive leucylspecific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis
    • Miyashita, H., Yamazaki, T., Akada, T., Niizeki, O., Ogawa, M., Nishikawa, S., and Sato, Y. (2002) A mouse orthologue of puromycin-insensitive leucylspecific aminopeptidase is expressed in endothelial cells and plays an important role in angiogenesis. Blood 99, 3241-3249
    • (2002) Blood , vol.99 , pp. 3241-3249
    • Miyashita, H.1    Yamazaki, T.2    Akada, T.3    Niizeki, O.4    Ogawa, M.5    Nishikawa, S.6    Sato, Y.7
  • 26
    • 0034129184 scopus 로고    scopus 로고
    • Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP
    • Schomburg, L., Kollmus, H., Friedrichsen, S., and Bauer, K. (2000) Molecular characterization of a puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP. Eur. J. Biochem. 267, 3198-3207
    • (2000) Eur. J. Biochem. , vol.267 , pp. 3198-3207
    • Schomburg, L.1    Kollmus, H.2    Friedrichsen, S.3    Bauer, K.4
  • 28
    • 0042206848 scopus 로고    scopus 로고
    • An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding
    • Cui, X., Rouhani, F. N., Hawari, F., and Levine, S. J. (2003) An aminopeptidase, ARTS-1, is required for interleukin-6 receptor shedding. J. Biol. Chem. 278, 28677-28685
    • (2003) J. Biol. Chem. , vol.278 , pp. 28677-28685
    • Cui, X.1    Rouhani, F.N.2    Hawari, F.3    Levine, S.J.4
  • 29
    • 0345735829 scopus 로고    scopus 로고
    • Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding
    • Cui, X., Rouhani, F. N., Hawari, F., and Levine, S. J. (2003) Shedding of the type II IL-1 decoy receptor requires a multifunctional aminopeptidase, aminopeptidase regulator of TNF receptor type 1 shedding. J. Immunol. 171, 6814-6819
    • (2003) J. Immunol. , vol.171 , pp. 6814-6819
    • Cui, X.1    Rouhani, F.N.2    Hawari, F.3    Levine, S.J.4
  • 30
    • 79958709420 scopus 로고    scopus 로고
    • Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-γ
    • Goto, Y., Ogawa, K., Hattori, A., and Tsujimoto, M. (2011) Secretion of endoplasmic reticulum aminopeptidase 1 is involved in the activation of macrophages induced by lipopolysaccharide and interferon-γ. J. Biol. Chem. 286, 21906-21914
    • (2011) J. Biol. Chem. , vol.286 , pp. 21906-21914
    • Goto, Y.1    Ogawa, K.2    Hattori, A.3    Tsujimoto, M.4
  • 31
    • 84899576357 scopus 로고    scopus 로고
    • TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages
    • Goto, Y., Ogawa, K., Nakamura, T. J., Hattori, A., and Tsujimoto, M. (2014) TLR-mediated secretion of endoplasmic reticulum aminopeptidase 1 from macrophages. J. Immunol. 192, 4443-4452
    • (2014) J. Immunol. , vol.192 , pp. 4443-4452
    • Goto, Y.1    Ogawa, K.2    Nakamura, T.J.3    Hattori, A.4    Tsujimoto, M.5
  • 32
    • 0034769118 scopus 로고    scopus 로고
    • Nitric oxide and the immune response
    • Bogdan, C. (2001) Nitric oxide and the immune response. Nat. Immunol. 2, 907-916
    • (2001) Nat. Immunol. , vol.2 , pp. 907-916
    • Bogdan, C.1
  • 34
    • 0035032518 scopus 로고    scopus 로고
    • Upregulation of inducible nitric oxide synthase and cytokine secretion in peripheral blood monocytes from pulmonary tuberculosis patients
    • Wang, C. H., Lin, H. C., Liu, C. Y., Huang, K. H., Huang, T. T., Yu, C. T., and Kuo, H. P. (2001) Upregulation of inducible nitric oxide synthase and cytokine secretion in peripheral blood monocytes from pulmonary tuberculosis patients. Int. J. Tuberc. Lung Dis. 5, 283-291
    • (2001) Int. J. Tuberc. Lung Dis. , vol.5 , pp. 283-291
    • Wang, C.H.1    Lin, H.C.2    Liu, C.Y.3    Huang, K.H.4    Huang, T.T.5    Yu, C.T.6    Kuo, H.P.7
  • 35
    • 0025787512 scopus 로고
    • L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae
    • Adams, L. B., Franzblau, S. G., Vavrin, Z., Hibbs, J. B. Jr., and Krahenbuhl, J. L. (1991) L-arginine-dependent macrophage effector functions inhibit metabolic activity of Mycobacterium leprae. J. Immunol. 147, 1642-1646
    • (1991) J. Immunol. , vol.147 , pp. 1642-1646
    • Adams, L.B.1    Franzblau, S.G.2    Vavrin, Z.3    Hibbs, J.B.4    Krahenbuhl, J.L.5
  • 36
    • 0036259784 scopus 로고    scopus 로고
    • Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities
    • Alam, M. S., Akaike, T., Okamoto, S., Kubota, T., Yoshitake, J., Sawa, T., Miyamoto, Y., Tamura, F., and Maeda, H. (2002) Role of nitric oxide in host defense in murine salmonellosis as a function of its antibacterial and antiapoptotic activities. Infect. Immun. 70, 3130-3142
    • (2002) Infect. Immun. , vol.70 , pp. 3130-3142
    • Alam, M.S.1    Akaike, T.2    Okamoto, S.3    Kubota, T.4    Yoshitake, J.5    Sawa, T.6    Miyamoto, Y.7    Tamura, F.8    Maeda, H.9
  • 37
    • 0037099165 scopus 로고    scopus 로고
    • Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis
    • Choi, H. S., Rai, P. R., Chu, H. W., Cool, C, and Chan, E. D. (2002) Analysis of nitric oxide synthase and nitrotyrosine expression in human pulmonary tuberculosis. Am. J. Respir. Crit. Care Med. 166, 178-186
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , pp. 178-186
    • Choi, H.S.1    Rai, P.R.2    Chu, H.W.3    Cool, C.4    Chan, E.D.5
  • 38
    • 84859487532 scopus 로고    scopus 로고
    • Nitric oxide synthases: Regulation and function
    • 837a-837d
    • Forstermann, U. and Sessa, W. C. (2012) Nitric oxide synthases: regulation and function. Eur. Heart J. 33, 829-837, 837a-837d
    • (2012) Eur. Heart J. , vol.33 , pp. 829-837
    • Forstermann, U.1    Sessa, W.C.2
  • 41
    • 0002540140 scopus 로고    scopus 로고
    • Regulation of arginine availability and its impact on NO synthesis in Nitric Oxide
    • Ignarro, L. J., ed., Academic Press, New York
    • Morris, S. M. Jr. (2009) Regulation of arginine availability and its impact on NO synthesis in Nitric Oxide: Biology and Pathobiology (Ignarro, L. J., ed.) pp. 187-197, Academic Press, New York
    • (2009) Biology and Pathobiology , pp. 187-197
    • Morris, S.M.1
  • 42
    • 0021868687 scopus 로고
    • Vascular, plasma membrane aminopeptidase M. Metabolism of vasoactive peptides
    • Palmieri, F. E., Petrelli, J. J., and Ward, P. E. (1985) Vascular, plasma membrane aminopeptidase M. Metabolism of vasoactive peptides. Biochem. Pharmacol. 34, 2309-2317
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 2309-2317
    • Palmieri, F.E.1    Petrelli, J.J.2    Ward, P.E.3
  • 44
    • 0042357061 scopus 로고    scopus 로고
    • Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases
    • Tanioka, T., Hattori, A., Masuda, S., Nomura, Y., Nakayama, H., Mizutani, S., and Tsujimoto, M. (2003) Human leukocyte-derived arginine aminopeptidase. The third member of the oxytocinase subfamily of aminopeptidases. J. Biol. Chem. 278, 32275-32283
    • (2003) J. Biol. Chem. , vol.278 , pp. 32275-32283
    • Tanioka, T.1    Hattori, A.2    Masuda, S.3    Nomura, Y.4    Nakayama, H.5    Mizutani, S.6    Tsujimoto, M.7
  • 45
    • 0033986606 scopus 로고    scopus 로고
    • Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: Role of cationic amino acid transporters
    • Closs, E. I., Scheld, J. S., Sharafi, M., and Forstermann, U. (2000) Substrate supply for nitric-oxide synthase in macrophages and endothelial cells: role of cationic amino acid transporters. Mol. Pharmacol. 57, 68-74
    • (2000) Mol. Pharmacol. , vol.57 , pp. 68-74
    • Closs, E.I.1    Scheld, J.S.2    Sharafi, M.3    Forstermann, U.4
  • 46
    • 0026560972 scopus 로고
    • L-arginine transport is increased in macrophages generating nitric oxide
    • Bogle, R. G., Baydoun, A. R., Pearson, J. D., Moncada, S., and Mann, G. E. (1992) L-arginine transport is increased in macrophages generating nitric oxide. Biochem. J. 284 (Pt 1), 15-18
    • (1992) Biochem. J. , vol.284 , pp. 15-18
    • Bogle, R.G.1    Baydoun, A.R.2    Pearson, J.D.3    Moncada, S.4    Mann, G.E.5
  • 47
    • 0035027566 scopus 로고    scopus 로고
    • Carboxypeptidase D is up-regulated in raw 264.7 macrophages and stimulates nitric oxide synthesis by cells in arginine-free medium
    • Hadkar, V. and Skidgel, R. A. (2001) Carboxypeptidase D is up-regulated in raw 264.7 macrophages and stimulates nitric oxide synthesis by cells in arginine-free medium. Mol. Pharmacol. 59, 1324-1332
    • (2001) Mol. Pharmacol. , vol.59 , pp. 1324-1332
    • Hadkar, V.1    Skidgel, R.A.2
  • 49
    • 78649498961 scopus 로고    scopus 로고
    • Expression, regulation and functional activities of aminopeptidase N (EC 3.4.11.2; APN; CD13) on murine macrophage J774 cell line
    • Gabrilovac, J., Cupic, B., Zivkovic, E., Horvat, L., and Majhen, D. (2011) Expression, regulation and functional activities of aminopeptidase N (EC 3.4.11.2; APN; CD13) on murine macrophage J774 cell line. Immunobiology 216, 132-144
    • (2011) Immunobiology , vol.216 , pp. 132-144
    • Gabrilovac, J.1    Cupic, B.2    Zivkovic, E.3    Horvat, L.4    Majhen, D.5
  • 51
  • 53
    • 34547127192 scopus 로고    scopus 로고
    • Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases
    • Maruyama, M., Hattori, A., Goto, Y., Ueda, M., Maeda, M., Fujiwara, H, and Tsujimoto, M. (2007) Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases. J. Biol. Chem. 282, 20088-20096
    • (2007) J. Biol. Chem. , vol.282 , pp. 20088-20096
    • Maruyama, M.1    Hattori, A.2    Goto, Y.3    Ueda, M.4    Maeda, M.5    Fujiwara, H.6    Tsujimoto, M.7
  • 55
    • 84879883082 scopus 로고    scopus 로고
    • ERAP1 in ankylosing spondylitis: Genetics, biology and pathogenetic role
    • Alvarez-Navarro, C. and Lopez de Castro, J. A. (2013) ERAP1 in ankylosing spondylitis: genetics, biology and pathogenetic role. Curr. Opin. Rheumatol. 25, 419-425
    • (2013) Curr. Opin. Rheumatol. , vol.25 , pp. 419-425
    • Alvarez-Navarro, C.1    Lopez De Castro, J.A.2
  • 56
    • 35748981184 scopus 로고    scopus 로고
    • Association scan of 14, 500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
    • Wellcome Trust Case Control, Consorsium. (2007) Association scan of 14, 500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat. Genet. 39, 1329-1337
    • (2007) Nat. Genet. , vol.39 , pp. 1329-1337
    • Wellcome Trust Case Control, Consorsium,1
  • 59
    • 0036192091 scopus 로고    scopus 로고
    • Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension
    • Yamamoto, N., Nakayama, J., Yamakawa-Kobayashi, K., Hamaguchi, H., Miyazaki, R., and Arinami, T. (2002) Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension. Hum. Mutat. 19, 251-257
    • (2002) Hum. Mutat. , vol.19 , pp. 251-257
    • Yamamoto, N.1    Nakayama, J.2    Yamakawa-Kobayashi, K.3    Hamaguchi, H.4    Miyazaki, R.5    Arinami, T.6
  • 60
    • 33644908217 scopus 로고    scopus 로고
    • Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1
    • Goto, Y., Hattori, A., Ishii, Y., and Tsujimoto, M. (2006) Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1. FEBS Lett. 580, 1833-1838
    • (2006) FEBS Lett. , vol.580 , pp. 1833-1838
    • Goto, Y.1    Hattori, A.2    Ishii, Y.3    Tsujimoto, M.4


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