-
1
-
-
79952232216
-
Global cancer statistics
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, Forman D. Global cancer statistics. CA Cancer J Clin 2011; 61: 69-90.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
Forman, D.6
-
2
-
-
0034995765
-
Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis
-
Laurent-Puig P, Legoix P, Bluteau O, Belghiti J, Franco D, Binot F et al. Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis. Gastroenterology 2001; 120: 1763-1773.
-
(2001)
Gastroenterology
, vol.120
, pp. 1763-1773
-
-
Laurent-Puig, P.1
Legoix, P.2
Bluteau, O.3
Belghiti, J.4
Franco, D.5
Binot, F.6
-
3
-
-
0037391756
-
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
-
Ye QH, Qin LX, Forgues M, He P, Kim JW, Peng AC et al. Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning. Nat Med 2003; 9: 416-423.
-
(2003)
Nat Med
, vol.9
, pp. 416-423
-
-
Ye, Q.H.1
Qin, L.X.2
Forgues, M.3
He, P.4
Kim, J.W.5
Peng, A.C.6
-
4
-
-
4544273428
-
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling
-
Lee JS, Chu IS, Heo J, Calvisi DF, Sun Z, Roskams T et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 2004; 40: 667-676.
-
(2004)
Hepatology
, vol.40
, pp. 667-676
-
-
Lee, J.S.1
Chu, I.S.2
Heo, J.3
Calvisi, D.F.4
Sun, Z.5
Roskams, T.6
-
5
-
-
33645742425
-
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells
-
Lee JS, Heo J, Libbrecht L, Chu IS, Kaposi-Novak P, Calvisi DF et al. A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells. Nat Med 2006; 12: 410-416.
-
(2006)
Nat Med
, vol.12
, pp. 410-416
-
-
Lee, J.S.1
Heo, J.2
Libbrecht, L.3
Chu, I.S.4
Kaposi-Novak, P.5
Calvisi, D.F.6
-
6
-
-
33747029250
-
Prediction of venous metastases, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment
-
Budhu A, Forgues M, Ye QH, Jia LH, He P, Zanetti KA et al. Prediction of venous metastases, recurrence and prognosis in hepatocellular carcinoma based on a unique immune response signature of the liver microenvironment. Cancer Cell 2006; 10: 99-111.
-
(2006)
Cancer Cell
, vol.10
, pp. 99-111
-
-
Budhu, A.1
Forgues, M.2
Ye, Q.H.3
Jia, L.H.4
He, P.5
Zanetti, K.A.6
-
7
-
-
33846463379
-
Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets
-
Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E et al. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 2007; 45: 42-52.
-
(2007)
Hepatology
, vol.45
, pp. 42-52
-
-
Boyault, S.1
Rickman, D.S.2
De Reynies, A.3
Balabaud, C.4
Rebouissou, S.5
Jeannot, E.6
-
8
-
-
40449099255
-
EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma
-
Yamashita T, Forgues M, Wang W, Kim JW, Ye Q, Jia H et al. EpCAM and alpha-fetoprotein expression defines novel prognostic subtypes of hepatocellular carcinoma. Cancer Res 2008; 68: 1451-1461.
-
(2008)
Cancer Res
, vol.68
, pp. 1451-1461
-
-
Yamashita, T.1
Forgues, M.2
Wang, W.3
Kim, J.W.4
Ye, Q.5
Jia, H.6
-
9
-
-
70349739285
-
Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma
-
Hoshida Y, Nijman SM, Kobayashi M, Chan JA, Brunet JP, Chiang DY et al. Integrative transcriptome analysis reveals common molecular subclasses of human hepatocellular carcinoma. Cancer Res 2009; 69: 7385-7392.
-
(2009)
Cancer Res
, vol.69
, pp. 7385-7392
-
-
Hoshida, Y.1
Nijman, S.M.2
Kobayashi, M.3
Chan, J.A.4
Brunet, J.P.5
Chiang, D.Y.6
-
10
-
-
0035871310
-
Experience of 1000 patients who underwent hepatectomy for small hepatocellular carcinoma
-
Zhou XD, Tang ZY, Yang BH, Lin ZY, Ma ZC, Ye SL et al. Experience of 1000 patients who underwent hepatectomy for small hepatocellular carcinoma. Cancer 2001; 91: 1479-1486.
-
(2001)
Cancer
, vol.91
, pp. 1479-1486
-
-
Zhou, X.D.1
Tang, Z.Y.2
Yang, B.H.3
Lin, Z.Y.4
Ma, Z.C.5
Ye, S.L.6
-
11
-
-
47949116252
-
Sorafenib in advanced hepatocellular carcinoma
-
Llovet JM, Ricci S, Mazzaferro V, Hilgard P, Gane E, Blanc JF et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390.
-
(2008)
N Engl J Med
, vol.359
, pp. 378-390
-
-
Llovet, J.M.1
Ricci, S.2
Mazzaferro, V.3
Hilgard, P.4
Gane, E.5
Blanc, J.F.6
-
13
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646-674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
14
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Stephens PJ, Tarpey PS, Davies H, Van LP, Greenman C, Wedge DC et al. The landscape of cancer genes and mutational processes in breast cancer. Nature 2012; 486: 400-404.
-
(2012)
Nature
, vol.486
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
Van Lp Greenman, C.4
Wedge, D.C.5
-
15
-
-
84861625981
-
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
-
Guichard C, Amaddeo G, Imbeaud S, Ladeiro Y, Pelletier L, Maad IB et al. Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma. Nat Genet 2012; 44: 694-698.
-
(2012)
Nat Genet
, vol.44
, pp. 694-698
-
-
Guichard, C.1
Amaddeo, G.2
Imbeaud, S.3
Ladeiro, Y.4
Pelletier, L.5
Maad, I.B.6
-
16
-
-
84864465226
-
Clinical implications of cancer stem cell biology in hepatocellular carcinoma
-
Ji J, Wang XW. Clinical implications of cancer stem cell biology in hepatocellular carcinoma. Semin Oncol 2012; 39: 461-472.
-
(2012)
Semin Oncol
, vol.39
, pp. 461-472
-
-
Ji, J.1
Wang, X.W.2
-
17
-
-
84877156945
-
Cancer stem cells in the development of liver cancer
-
Yamashita T, Wang XW. Cancer stem cells in the development of liver cancer. J Clin Invest 2013; 123: 1911-1918.
-
(2013)
J Clin Invest
, vol.123
, pp. 1911-1918
-
-
Yamashita, T.1
Wang, X.W.2
-
18
-
-
68949170622
-
Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells
-
Ji J, Yamashita T, Budhu A, Forgues M, Jia HL, Li C et al. Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells. Hepatology 2009; 50: 472-480.
-
(2009)
Hepatology
, vol.50
, pp. 472-480
-
-
Ji, J.1
Yamashita, T.2
Budhu, A.3
Forgues, M.4
Jia, H.L.5
Li, C.6
-
19
-
-
36348991571
-
Activation of hepatic stem cell marker EpCAM by Wnt-ß-catenin signaling in hepatocellular carcinoma
-
Yamashita T, Budhu A, Forgues M, Wang XW. Activation of hepatic stem cell marker EpCAM by Wnt-ß-catenin signaling in hepatocellular carcinoma. Cancer Res 2007; 67: 10831-10839.
-
(2007)
Cancer Res
, vol.67
, pp. 10831-10839
-
-
Yamashita, T.1
Budhu, A.2
Forgues, M.3
Wang, X.W.4
-
20
-
-
60449087921
-
EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features
-
Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY et al. EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features. Gastroenterology 2009; 136: 1012-1024.
-
(2009)
Gastroenterology
, vol.136
, pp. 1012-1024
-
-
Yamashita, T.1
Ji, J.2
Budhu, A.3
Forgues, M.4
Yang, W.5
Wang, H.Y.6
-
21
-
-
84859393351
-
Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival
-
Roessler S, Long EL, Budhu A, Chen Y, Zhao X, Ji J et al. Integrative genomic identification of genes on 8p associated with hepatocellular carcinoma progression and patient survival. Gastroenterology 2012; 142: 957-966.
-
(2012)
Gastroenterology
, vol.142
, pp. 957-966
-
-
Roessler, S.1
Long, E.L.2
Budhu, A.3
Chen, Y.4
Zhao, X.5
Ji, J.6
-
22
-
-
33745932545
-
An anthropoid-specific segmental duplication on human chromosome 1q22
-
Kuryshev VY, Vorobyov E, Zink D, Schmitz J, Rozhdestvensky TS, Munstermann E et al. An anthropoid-specific segmental duplication on human chromosome 1q22. Genomics 2006; 88: 143-151.
-
(2006)
Genomics
, vol.88
, pp. 143-151
-
-
Kuryshev, V.Y.1
Vorobyov, E.2
Zink, D.3
Schmitz, J.4
Rozhdestvensky, T.S.5
Munstermann, E.6
-
23
-
-
4143132121
-
Promoter hypermethylation of resected bronchial margins: A field defect of changes?
-
Guo M, House MG, Hooker C, Han Y, Heath E, Gabrielson E et al. Promoter hypermethylation of resected bronchial margins: a field defect of changes? Clin Cancer Res 2004; 10: 5131-5136.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5131-5136
-
-
Guo, M.1
House, M.G.2
Hooker, C.3
Han, Y.4
Heath, E.5
Gabrielson, E.6
-
24
-
-
0030751395
-
Norcantharidin inhibits growth of human HepG2 cell-transplanted tumor in nude mice and prolongs host survival
-
Yang EB, Tang WY, Zhang K, Cheng LY, Mack PO. Norcantharidin inhibits growth of human HepG2 cell-transplanted tumor in nude mice and prolongs host survival. Cancer Lett 1997; 117: 93-98.
-
(1997)
Cancer Lett
, vol.117
, pp. 93-98
-
-
Yang, E.B.1
Tang, W.Y.2
Zhang, K.3
Cheng, L.Y.4
Mack, P.O.5
-
25
-
-
27144491930
-
Complete tumor response following intratumoral 32P BioSilicon on human hepatocellular and pancreatic carcinoma xenografts in nude mice
-
Zhang K, Loong SL, Connor S, Yu SW, Tan SY, Ng RT et al. Complete tumor response following intratumoral 32P BioSilicon on human hepatocellular and pancreatic carcinoma xenografts in nude mice. Clin Cancer Res 2005; 11: 7532-7537.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7532-7537
-
-
Zhang, K.1
Loong, S.L.2
Connor, S.3
Yu, S.W.4
Tan, S.Y.5
Ng, R.T.6
-
26
-
-
2342445865
-
YY1AP, a novel co-activator of YY1
-
Wang CY, Liang YJ, Lin YS, Shih HM, Jou YS, Yu WC. YY1AP, a novel co-activator of YY1. J Biol Chem 2004; 279: 17750-17755.
-
(2004)
J Biol Chem
, vol.279
, pp. 17750-17755
-
-
Wang, C.Y.1
Liang, Y.J.2
Lin, Y.S.3
Shih, H.M.4
Jou, Y.S.5
Yu, W.C.6
-
27
-
-
79251565823
-
Genomic profiling of HMGN1 reveals an association with chromatin at regulatory regions
-
Cuddapah S, Schones DE, Cui K, Roh TY, Barski A, Wei G et al. Genomic profiling of HMGN1 reveals an association with chromatin at regulatory regions. Mol Cell Biol 2011; 31: 700-709.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 700-709
-
-
Cuddapah, S.1
Schones, D.E.2
Cui, K.3
Roh, T.Y.4
Barski, A.5
Wei, G.6
-
28
-
-
0037019333
-
Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast
-
Sun ZW, Allis CD. Ubiquitination of histone H2B regulates H3 methylation and gene silencing in yeast. Nature 2002; 418: 104-108.
-
(2002)
Nature
, vol.418
, pp. 104-108
-
-
Sun, Z.W.1
Allis, C.D.2
-
29
-
-
23944445861
-
BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex
-
Laribee RN, Krogan NJ, Xiao T, Shibata Y, Hughes TR, Greenblatt JF et al. BUR kinase selectively regulates H3 K4 trimethylation and H2B ubiquitylation through recruitment of the PAF elongation complex. Curr Biol 2005; 15: 1487-1493.
-
(2005)
Curr Biol
, vol.15
, pp. 1487-1493
-
-
Laribee, R.N.1
Krogan, N.J.2
Xiao, T.3
Shibata, Y.4
Hughes, T.R.5
Greenblatt, J.F.6
-
30
-
-
36849046285
-
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS
-
Lee JS, Shukla A, Schneider J, Swanson SK, Washburn MP, Florens L et al. Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell 2007; 131: 1084-1096.
-
(2007)
Cell
, vol.131
, pp. 1084-1096
-
-
Lee, J.S.1
Shukla, A.2
Schneider, J.3
Swanson, S.K.4
Washburn, M.P.5
Florens, L.6
-
31
-
-
65249105512
-
RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells
-
Kim J, Guermah M, McGinty RK, Lee JS, Tang Z, Milne TA et al. RAD6-mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 2009; 137: 459-471.
-
(2009)
Cell
, vol.137
, pp. 459-471
-
-
Kim, J.1
Guermah, M.2
McGinty, R.K.3
Lee, J.S.4
Tang, Z.5
Milne, T.A.6
-
32
-
-
16244384503
-
A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation
-
Kizer KO, Phatnani HP, Shibata Y, Hall H, Greenleaf AL, Strahl BD. A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation. Mol Cell Biol 2005; 25: 3305-3316.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 3305-3316
-
-
Kizer, K.O.1
Phatnani, H.P.2
Shibata, Y.3
Hall, H.4
Greenleaf, A.L.5
Strahl, B.D.6
-
33
-
-
80054787805
-
Targeting histone demethylases: A new avenue for the fight against cancer
-
Rotili D, Mai A. Targeting histone demethylases: a new avenue for the fight against cancer. Genes Cancer 2011; 2: 663-679.
-
(2011)
Genes Cancer
, vol.2
, pp. 663-679
-
-
Rotili, D.1
Mai, A.2
-
35
-
-
77249119762
-
The landscape of somatic copy-number alteration across human cancers
-
Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J et al. The landscape of somatic copy-number alteration across human cancers. Nature 2010; 463: 899-905.
-
(2010)
Nature
, vol.463
, pp. 899-905
-
-
Beroukhim, R.1
Mermel, C.H.2
Porter, D.3
Wei, G.4
Raychaudhuri, S.5
Donovan, J.6
-
36
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes SA, Bindal N, Bamford S, Cole C, Kok CY, Beare D et al. COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res 2011; 39: D945-D950.
-
(2011)
Nucleic Acids Res
, vol.39
, pp. D945-D950
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
Cole, C.4
Kok, C.Y.5
Beare, D.6
-
37
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E et al. Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 2012; 366: 883-892.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
38
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network, Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012; 487: 330-337.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
39
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network, Comprehensive genomic characterization of squamous cell lung cancers. Nature 2012; 489: 519-525.
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
40
-
-
84868204026
-
Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
-
Oishi N, Kumar MR, Roessler S, Ji J, Forgues M, Budhu A et al. Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma. Hepatology 2012; 56: 1792-1803.
-
(2012)
Hepatology
, vol.56
, pp. 1792-1803
-
-
Oishi, N.1
Kumar, M.R.2
Roessler, S.3
Ji, J.4
Forgues, M.5
Budhu, A.6
-
41
-
-
84875295407
-
Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes
-
Budhu A, Roessler S, Zhao X, Yu Z, Forgues M, Ji J et al. Integrated metabolite and gene expression profiles identify lipid biomarkers associated with progression of hepatocellular carcinoma and patient outcomes. Gastroenterology 2013; 144: 1066-1075.
-
(2013)
Gastroenterology
, vol.144
, pp. 1066-1075
-
-
Budhu, A.1
Roessler, S.2
Zhao, X.3
Yu, Z.4
Forgues, M.5
Ji, J.6
-
42
-
-
0037025173
-
Cancer Addiction to oncogenes-the Achilles heal of cancer
-
Weinstein IB. Cancer. Addiction to oncogenes-the Achilles heal of cancer. Science 2002; 297: 63-64.
-
(2002)
Science
, vol.297
, pp. 63-64
-
-
Weinstein, I.B.1
-
43
-
-
59149084182
-
Transcriptional repression of epithelial cell adhesion molecule contributes to p53 control of breast cancer invasion
-
Sankpal NV, Willman MW, Fleming TP, Mayfield JD, Gillanders WE. Transcriptional repression of epithelial cell adhesion molecule contributes to p53 control of breast cancer invasion. Cancer Res 2009; 69: 753-757.
-
(2009)
Cancer Res
, vol.69
, pp. 753-757
-
-
Sankpal, N.V.1
Willman, M.W.2
Fleming, T.P.3
Mayfield, J.D.4
Gillanders, W.E.5
-
44
-
-
78650361904
-
A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients
-
Roessler S, Jia HL, Budhu A, Forgues M, Ye QH, Lee JS et al. A unique metastasis gene signature enables prediction of tumor relapse in early-stage hepatocellular carcinoma patients. Cancer Res 2010; 70: 10202-10212.
-
(2010)
Cancer Res
, vol.70
, pp. 10202-10212
-
-
Roessler, S.1
Jia, H.L.2
Budhu, A.3
Forgues, M.4
Ye, Q.H.5
Lee, J.S.6
|