Flavonoid glycosides from Rubus chingii Hu fruits display anti-inflammatory activity through suppressing MAPKs activation in macrophages

Journal of Functional Foods

Volumn 18, Issue , 2015, Pages 235-243

  Zhang, Tian Tian ^a   Wang, Min ^b   Yang, Li ^a   Jiang, Jian Guo ^a   Zhao, Jing Wen ^b   Zhu, Wei ^b  

^a SOUTH CHINA UNIVERSITY OF TECHNOLOGY   (China)

^b GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Anti inflammation; Flavonoid glycosides; Macrophages; MAPK; Rubus chingii Hu; Tiliroside

Indexed keywords

EID: 84942518299     PISSN: 17564646     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jff.2015.07.006     Document Type: Article

References (36)

1. Aggarwal B., Gupta S.C., Sung B. Curcumin: An orally bioavailable blocker of TNF and other pro-inflammatory biomarkers. British Journal of Pharmacology 2013, 169:1672-1692.
2. Benahmed M., Akkal S., Elomri A., Laouer H., Verite P., Seguin E. Constituents from Bupleurum montanum (Coss. & Dur.) (Apiaceae). Arabian Journal of Chemistry 2014, 7:1065-1069.
3. Byun E.B., Sung N.Y., Park J.N., Yang M.S., Park S.H., Byun E.H. Gamma-irradiated resveratrol negatively regulates LPS-induced MAPK and NF-κB signaling through TLR4 in macrophages. International Immunopharmacology 2015, 25:249-259.
4. Coulter J.A., McCarthy H.O., Xiang J., Roedl W., Wagner E., Robson T. Nitric oxide - A novel therapeutic for cancer. Nitric Oxide: Biology and Chemistry 2008, 19:192-198.
5. Ding H.Y. Extracts and constituents of Rubus chingii with 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging activity. International Journal of Molecular Sciences 2011, 12:3941-3949.
6. Elsherbiny N.M., Ahmad S., Naime M., Elsherbini A.M., Fulzele S., Al-Gayyar M.M., Eissa L.A., El-Shishtawy M.M., Liou G.I. ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy. Life Science 2013, 93:78-88.
7. Garcia-Perez M.E., Allaeys I., Rusu D., Pouliot R., Janezic T.S., Poubelle P.E. Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-alpha-activated psoriatic keratinocytes: Impact on NF-kappa B pathway. Journal of Ethnopharmacology 2014, 151:265-278.
8. Gautam R., Jachak S.M. Recent developments in anti-inflammatory natural products. Medicinal Research Reviews 2009, 29:767-820.
9. Gunawardena D., Karunaweera N., Lee S., van der Kooy F., Harman D.G., Raju R., Bennett L., Gyengesi E., Sucher N.J., Munch G. Anti-inflammatory activity of cinnamon (C. zeylanicum and C. cassia) extracts - Identification of E-cinnamaldehyde and o-methoxy cinnamaldehyde as the most potent bioactive compounds. Food & Function 2015, 6:910-919.
10. Hasnaoui N., Wathelet B., Jimenez-Araujo A.V. Valorization of pomegranate peel from 12 cultivars: Dietary fibre composition, antioxidant capacity and functional properties. Food Chemistry 2014, 160:196-203.
11. Hooshmand S., Kumar A., Zhang J.Y., Johnson S.A., Chai S.C., Arjmandi B.H. Evidence for anti-inflammatory and antioxidative properties of dried plum polyphenols in macrophage RAW 264.7 cells. Food & Function 2015, 6:1719-1725.
12. Ilic N.M., Dey M., Poulev A.A., Logendra S., Kuhn P.E., Raskin I. Anti-inflammatory activity of grains of Paradise (Aframomum melegueta Schum) extract. Journal of Agricultural and Food Chemistry 2014, 62:10452-10457.
13. Kanwar J.R., Kanwar R.K., Burrow H., Baratchi S. Recent advances on the roles of NO in cancer and chronic inflammatory disorders. Current Medicinal Chemistry 2009, 16:2373-2394.
14. Liao W.Z., Luo Z., Liu D., Ning Z.X., Yang J.G., Ren J.Y. Structure characterization of a novel polysaccharide from Dictyophora indusiata and its macrophage immunomodulatory activities. Journal of Agricultural and Food Chemistry 2015, 63:535-544.
15. Ma X.Q., Zheng C.J., Zhang Y., Hu C.L., Lin B., Fu X.Y., Han L.Y., Xu L.S., Rahman K., Qin L.P. Antiosteoporotic flavonoids from Podocarpium podocarpum. Phytochemistry Letters 2013, 6:118-122.
16. Mattiello T., Fiore G., Brown E.R., d'Ischia M., Palumbo A. Nitric oxide mediates the glutamate-dependent pathway for neurotransmission in Sepia officinalis chromatophore organs. Journal of Biological Chemistry 2010, 285:24154-24163.
17. Mueller D., Triebel S., Rudakovski O., Richling E. Influence of triterpenoids present in apple peel on inflammatory gene expression associated with inflammatory bowel disease (IBD). Food Chemistry 2013, 139:339-346.
18. Ndhlala A.R., Aderogba M.A., Ncube B., Staden J.V. Anti-oxidative and cholinesterase inhibitory effects of leaf extracts and their isolated compounds from two closely related Croton species. Molecules 2013, 18:1916-1932.
19. Pinheiro M.M.G., Fernandes S.B.O., Fingolo C.E., Boylan F., Fernandes P.D. Anti-inflammatory activity of ethanol extract and fractions from Couroupita guianensis Aublet leaves. Journal of Ethnopharmacology 2013, 146:324-330.
20. Sala A., Recio M.C., Schinella G.R., Manez S., Giner R.M., Cerda-Nicolas M., Rios J.L. Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside. European Journal of Pharmacology 2003, 461:53-61.
21. Sung J., Sung M., Kim Y., Ham H., Jeong H.S., Lee J. Anti-inflammatory effect of methanol extract from Erigeron Canadensis L. may be involved with upregulation of heme oxygenase-1 expression and suppression of NF-κB and MAPKs activation in macrophages. Nutrition Research and Practice 2014, 8:352-359.
22. Tandon M., Chen Z.J., Pratap J. Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells. Breast Cancer Research 2014, 16:R16.
23. Tao J.Y., Zheng G.H., Zhao L., Wu J.G., Zhang X.Y., Zhang S.L., Huang Z.J., Xiong F.L., Li C.M. Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells. Journal of Ethnopharmacology 2009, 123:97-105.
24. Uzbay T.I., Oglesby M.W. Nitric oxide and substance dependence. Neuroscience and Biobehavioral Reviews 2001, 25:43-52.
25. Vuolteenaho K., Moilanen T., Knowles R.G., Moilanen E. The role of nitric oxide in osteoarthritis. Scandinavian Journal of Rheumatology 2007, 36:247-258.
26. Xie Z.S., Huang J.Y., Xie Z.Y., Yu X.X., Yang M., Yang D.P., Xu X.J. Isolation and purification of isoquercitrin and quercitrin from Hypericum Japonicum Thunb.ex Murray by counter-current chromatography. Separation Science and Technology 2014, 49:778-782.
27. Yang J.H., Li S.C., Xie C.F., Ye H.Y., Tang H., Chen L.J., Peng A.H. Anti-inflammatory activity of ethyl acetate fraction of the seeds of Brucea Javanica. Journal of Ethnopharmacology 2013, 147:442-446.
28. Yoon W.J., Lee N.H., Hyun C.G. Limonene suppresses lipopolysaccharide-induced production of nitric oxide, prostaglandin E2, and pro-inflammatory cytokines in RAW 264.7 macrophages. Journal of Oleo Science 2010, 59:415-421.
29. Yoshimura A. Signal transduction of inflammatory cytokines and tumor development. Cancer Science 2006, 97:439-447.
30. Zhang T.T., Jiang J.G. Analyses on essential oil components from the unripe fruits of Rubus chingii Hu by different methods and their comparative cytotoxic and anti-complement activities. Food Analytical Methods 2015, 8:937-944.
31. Zhang T.T., Lu C.L., Jiang J.G. Bioactivity evaluation of ingredients identified from the fruits of Amomum tsaoko Crevost et Lemaire, a Chinese spice. Food & Function 2014, 5:1747-1754.
32. Zhang T.T., Lu C.L., Jiang J.G., Wang M., Wang D.M., Zhu W. Bioactivities and extraction optimization of crude polysaccharides from the fruits and leaves of Rubus chingii Hu. Carbohydrate Polymers 2015, 130:307-315.
33. Zhang T.T., Xu X.L., Jiang M.H., Jiang J.G. Hepatoprotective function of Penthorum chinense Pursh. Food & Function 2013, 4:1581-1585.
34. Zhang T.T., Yang L., Jiang J.G. Bioactive comparison of main components from unripe fruits of Rubus chingii Hu and identification of the effective component. Food & Function 2015, 6:2205-2214. 10.1039/c5fo00406c.
35. Zhang T.T., Yang L., Jiang J.G. Effects of thonningianin A in natural foods on apoptosis and cell cycle arrest of HepG-2 human hepatocellular carcinoma cells. Food & Function 2015, 10.1039/c5fo00388a.
36. Zhu Y.D., Liu Y., Zhan Y., Liu L., Xu Y.J., Xu T.H., Liu T.H. Preparative isolation and purification of five flavonoid glycosides and one benzophenone galloyl glycoside from Psidium guajava by High-Speed Counter-Current Chromatography (HSCCC). Molecules 2013, 18:15648-15661.