메뉴 건너뛰기




Volumn 93, Issue 2-3, 2013, Pages 78-88

ABT-702, an adenosine kinase inhibitor, attenuates inflammation in diabetic retinopathy

Author keywords

Adenosine kinase; Diabetic retinopathy; Inflammation

Indexed keywords

4 AMINO 5 (3 BROMOPHENYL) 7 (6 MORPHOLINO 3 PYRIDINYL)PYRIDO[2,3 D]PYRIMIDINE; ADENOSINE KINASE; EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1; GLUCOSE; INTERCELLULAR ADHESION MOLECULE 1; STREPTOZOCIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84880229594     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2013.05.024     Document Type: Article
Times cited : (38)

References (43)
  • 1
    • 0037317423 scopus 로고    scopus 로고
    • A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat
    • V. Asnaghi, C. Gerhardinger, T. Hoehn, A. Adeboje, and M. Lorenzi A role for the polyol pathway in the early neuroretinal apoptosis and glial changes induced by diabetes in the rat Diabetes 52 2003 506 511
    • (2003) Diabetes , vol.52 , pp. 506-511
    • Asnaghi, V.1    Gerhardinger, C.2    Hoehn, T.3    Adeboje, A.4    Lorenzi, M.5
  • 2
    • 33750943168 scopus 로고    scopus 로고
    • Adenosine kinase, epilepsy and stroke: Mechanisms and therapies
    • D. Boison Adenosine kinase, epilepsy and stroke: mechanisms and therapies Trends Pharmacol Sci 27 2006 652 658
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 652-658
    • Boison, D.1
  • 3
    • 0030478842 scopus 로고    scopus 로고
    • Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-d-aspartate receptors
    • G.W. Bong, S. Rosengren, and G.S. Firestein Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-d-aspartate receptors J Clin Invest 98 1996 2779 2785
    • (1996) J Clin Invest , vol.98 , pp. 2779-2785
    • Bong, G.W.1    Rosengren, S.2    Firestein, G.S.3
  • 4
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 5
    • 30344486638 scopus 로고    scopus 로고
    • Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes
    • A.B. El-Remessy, M. Al-Shabrawey, Y. Khalifa, N.T. Tsai, R.B. Caldwell, and G.I. Liou Neuroprotective and blood-retinal barrier-preserving effects of cannabidiol in experimental diabetes Am J Pathol 168 2006 235 244
    • (2006) Am J Pathol , vol.168 , pp. 235-244
    • El-Remessy, A.B.1    Al-Shabrawey, M.2    Khalifa, Y.3    Tsai, N.T.4    Caldwell, R.B.5    Liou, G.I.6
  • 6
    • 57349100410 scopus 로고    scopus 로고
    • Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: Critical role of p38 MAPK activation
    • A.B. El-Remessy, Y. Tang, G. Zhu, S. Matragoon, Y. Khalifa, and E.K. Liu Neuroprotective effects of cannabidiol in endotoxin-induced uveitis: critical role of p38 MAPK activation Mol Vis 14 2008 2190 2203
    • (2008) Mol Vis , vol.14 , pp. 2190-2203
    • El-Remessy, A.B.1    Tang, Y.2    Zhu, G.3    Matragoon, S.4    Khalifa, Y.5    Liu, E.K.6
  • 7
    • 0842284006 scopus 로고    scopus 로고
    • Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis
    • N. Gouder, L. Scheurer, J.M. Fritschy, and D. Boison Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis J Neurosci 24 2004 692 701
    • (2004) J Neurosci , vol.24 , pp. 692-701
    • Gouder, N.1    Scheurer, L.2    Fritschy, J.M.3    Boison, D.4
  • 9
    • 79953188707 scopus 로고    scopus 로고
    • Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes
    • A.S. Ibrahim, A.B. El-Remessy, S. Matragoon, W. Zhang, Y. Patel, and S. Khan Retinal microglial activation and inflammation induced by amadori-glycated albumin in a rat model of diabetes Diabetes 60 2011 1122 1133
    • (2011) Diabetes , vol.60 , pp. 1122-1133
    • Ibrahim, A.S.1    El-Remessy, A.B.2    Matragoon, S.3    Zhang, W.4    Patel, Y.5    Khan, S.6
  • 11
    • 0033680092 scopus 로고    scopus 로고
    • ABT-702 (4-amino-5-(3-bromophenyl)-7-(6 morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse
    • M.F. Jarvis, H. Yu, K. Kohlhaas, K. Alexander, C.H. Lee, and M. Jiang ABT-702 (4-amino-5-(3-bromophenyl)-7-(6 morpholinopyridin-3-yl)pyrido[2, 3-d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties: I. In vitro characterization and acute antinociceptive effects in the mouse J Pharmacol Exp Ther 295 2000 1156 1164
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1156-1164
    • Jarvis, M.F.1    Yu, H.2    Kohlhaas, K.3    Alexander, K.4    Lee, C.H.5    Jiang, M.6
  • 13
    • 7044228789 scopus 로고    scopus 로고
    • A central role for inflammation in the pathogenesis of diabetic retinopathy
    • A.M. Joussen, V. Poulaki, M.L. Le, K. Koizumi, C. Esser, and H. Janicki A central role for inflammation in the pathogenesis of diabetic retinopathy FASEB J 18 2004 1450 1452
    • (2004) FASEB J , vol.18 , pp. 1450-1452
    • Joussen, A.M.1    Poulaki, V.2    Le, M.L.3    Koizumi, K.4    Esser, C.5    Janicki, H.6
  • 14
    • 68149131912 scopus 로고    scopus 로고
    • TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations
    • A.M. Joussen, S. Doehmen, M.L. Le, K. Koizumi, S. Radetzky, and T.U. Krohne TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations Mol Vis 15 2009 1418 1428
    • (2009) Mol Vis , vol.15 , pp. 1418-1428
    • Joussen, A.M.1    Doehmen, S.2    Le, M.L.3    Koizumi, K.4    Radetzky, S.5    Krohne, T.U.6
  • 15
    • 51849157860 scopus 로고    scopus 로고
    • Retinal ganglion cells in diabetes
    • T.S. Kern, and A.J. Barber Retinal ganglion cells in diabetes J Physiol 586 2008 4401 4408
    • (2008) J Physiol , vol.586 , pp. 4401-4408
    • Kern, T.S.1    Barber, A.J.2
  • 16
    • 0033697042 scopus 로고    scopus 로고
    • ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3- yl)pyrido[2,3 d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat
    • E.A. Kowaluk, J. Mikusa, C.T. Wismer, C.Z. Zhu, E. Schweitzer, and J.J. Lynch ABT-702 (4-amino-5-(3-bromophenyl)-7-(6-morpholino-pyridin- 3- yl)pyrido[2,3 d]pyrimidine), a novel orally effective adenosine kinase inhibitor with analgesic and anti-inflammatory properties. II. In vivo characterization in the rat J Pharmacol Exp Ther 295 2000 1165 1174
    • (2000) J Pharmacol Exp Ther , vol.295 , pp. 1165-1174
    • Kowaluk, E.A.1    Mikusa, J.2    Wismer, C.T.3    Zhu, C.Z.4    Schweitzer, E.5    Lynch, J.J.6
  • 17
    • 34247542013 scopus 로고    scopus 로고
    • Effects of curcumin on retinal oxidative stress and inflammation in diabetes
    • R.A. Kowluru, and M. Kanwar Effects of curcumin on retinal oxidative stress and inflammation in diabetes Nutr Metab 4 2007 8
    • (2007) Nutr Metab , vol.4 , pp. 8
    • Kowluru, R.A.1    Kanwar, M.2
  • 18
    • 33645115158 scopus 로고    scopus 로고
    • Adenosine inhibits tumor necrosis factor-alpha release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor
    • L.M. Kreckler, T.C. Wan, Z.D. Ge, and J.A. Auchampach Adenosine inhibits tumor necrosis factor-alpha release from mouse peritoneal macrophages via A2A and A2B but not the A3 adenosine receptor J Pharmacol Exp Ther 317 2006 172 180
    • (2006) J Pharmacol Exp Ther , vol.317 , pp. 172-180
    • Kreckler, L.M.1    Wan, T.C.2    Ge, Z.D.3    Auchampach, J.A.4
  • 19
    • 19344364430 scopus 로고    scopus 로고
    • Glucose upregulates adenosine transport in cultured aortic smooth muscle cells
    • G.P. Leung, R.Y. Man, and C.M. Tse Glucose upregulates adenosine transport in cultured aortic smooth muscle cells Am J Physiol Heart Circ Physiol 288 2005 2756 2762
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. 2756-2762
    • Leung, G.P.1    Man, R.Y.2    Tse, C.M.3
  • 20
    • 38849100495 scopus 로고    scopus 로고
    • Adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice
    • T. Li, G. Ren, T. Lusardi, A. Wilz, J.Q. Lan, and T. Iwasato adenosine kinase is a target for the prediction and prevention of epileptogenesis in mice J Clin Invest 118 2008 571 582
    • (2008) J Clin Invest , vol.118 , pp. 571-582
    • Li, T.1    Ren, G.2    Lusardi, T.3    Wilz, A.4    Lan, J.Q.5    Iwasato, T.6
  • 21
    • 58149269741 scopus 로고    scopus 로고
    • Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor
    • G.I. Liou, J.A. Auchampach, C.J. Hillard, G. Zhu, B. Yousufzai, and S. Mian Mediation of cannabidiol anti-inflammation in the retina by equilibrative nucleoside transporter and A2A adenosine receptor Invest Ophthalmol Vis Sci 49 2008 5526 5531
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 5526-5531
    • Liou, G.I.1    Auchampach, J.A.2    Hillard, C.J.3    Zhu, G.4    Yousufzai, B.5    Mian, S.6
  • 23
    • 54949157448 scopus 로고    scopus 로고
    • Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives
    • S.A. Madsen-Bouterse, and R.A. Kowluru Oxidative stress and diabetic retinopathy: pathophysiological mechanisms and treatment perspectives Rev Endocr Metab Disord 9 2008 315 327
    • (2008) Rev Endocr Metab Disord , vol.9 , pp. 315-327
    • Madsen-Bouterse, S.A.1    Kowluru, R.A.2
  • 24
    • 79952423622 scopus 로고    scopus 로고
    • Anti inflammatory effects of the A2A adenosine receptor
    • G.R. Milne, and T.M. Palmer Anti inflammatory effects of the A2A adenosine receptor Scientific World Journal 11 2011 320 339
    • (2011) Scientific World Journal , vol.11 , pp. 320-339
    • Milne, G.R.1    Palmer, T.M.2
  • 25
    • 47049088629 scopus 로고    scopus 로고
    • HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak
    • J.C. Morote-Garcia, P. Rosenberger, J. Kuhlicke, and H.K. Eltzschig HIF-1-dependent repression of adenosine kinase attenuates hypoxia-induced vascular leak Blood 111 2008 5571 5580
    • (2008) Blood , vol.111 , pp. 5571-5580
    • Morote-Garcia, J.C.1    Rosenberger, P.2    Kuhlicke, J.3    Eltzschig, H.K.4
  • 26
    • 0024512294 scopus 로고
    • Turnover of adenosine in plasma of human and dog blood
    • G.H. Möser, J. Schrader, and A. Deussen Turnover of adenosine in plasma of human and dog blood Am J Physiol 256 1989 799 806
    • (1989) Am J Physiol , vol.256 , pp. 799-806
    • Möser, G.H.1    Schrader, J.2    Deussen, A.3
  • 27
    • 0027935403 scopus 로고
    • Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices
    • M.A. Pak, H.L. Haas, U.K. Decking, and J. Schrader Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices Neuropharmacology 33 1994 1049 1053
    • (1994) Neuropharmacology , vol.33 , pp. 1049-1053
    • Pak, M.A.1    Haas, H.L.2    Decking, U.K.3    Schrader, J.4
  • 28
    • 74949123730 scopus 로고    scopus 로고
    • Compensatory upregulation of the adenosine system following phenylephrine-induced hypertrophy in cultured rat ventricular myocytes
    • T. Pang, X.T. Gan, D.J. Freeman, M.A. Cook, and M. Karmazyn Compensatory upregulation of the adenosine system following phenylephrine-induced hypertrophy in cultured rat ventricular myocytes Am J Physiol Heart Circ Physiol 298 2010 545 553
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. 545-553
    • Pang, T.1    Gan, X.T.2    Freeman, D.J.3    Cook, M.A.4    Karmazyn, M.5
  • 29
    • 0034839395 scopus 로고    scopus 로고
    • Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart
    • J. Peart, G.P. Matherne, R.J. Cerniway, and J.P. Headrick Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart Cardiovasc Res 52 2001 120 129
    • (2001) Cardiovasc Res , vol.52 , pp. 120-129
    • Peart, J.1    Matherne, G.P.2    Cerniway, R.J.3    Headrick, J.P.4
  • 30
    • 33845786142 scopus 로고    scopus 로고
    • Transgenic overexpression of adenosine kinase aggravates cell death in ischemia
    • G. Pignataro, R.P. Simon, and D. Boison Transgenic overexpression of adenosine kinase aggravates cell death in ischemia J Cereb Blood Flow Metab 27 2007 1 5
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1-5
    • Pignataro, G.1    Simon, R.P.2    Boison, D.3
  • 31
    • 37549033536 scopus 로고    scopus 로고
    • Boison D Downregulation ofhippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism
    • G. Pignataro, S. Maysami, F.E. Studer, A. Wilz, and R.P. Simon Boison D Downregulation ofhippocampal adenosine kinase after focal ischemia as potential endogenous neuroprotective mechanism J Cereb Blood Flow Metab 28 2008 17 23
    • (2008) J Cereb Blood Flow Metab , vol.28 , pp. 17-23
    • Pignataro, G.1    Maysami, S.2    Studer, F.E.3    Wilz, A.4    Simon, R.P.5
  • 32
    • 84856397889 scopus 로고    scopus 로고
    • Diabetic retinopathy and inflammation: Novel therapeutic targets
    • S. Rangasamy, P.G. McGuire, and A. Das Diabetic retinopathy and inflammation: novel therapeutic targets Middle East Afr J Ophthalmol 19 2012 52 59
    • (2012) Middle East Afr J Ophthalmol , vol.19 , pp. 52-59
    • Rangasamy, S.1    Mcguire, P.G.2    Das, A.3
  • 34
    • 33748450680 scopus 로고    scopus 로고
    • Shift of adenosine kinase expression from neurons to astrocytes during postnatal development suggests dual functionality of the enzyme
    • F.E. Studer, D.E. Fedele, A. Marowsky, C. Schwerdel, K. Wernli, and K. Vogt Shift of adenosine kinase expression from neurons to astrocytes during postnatal development suggests dual functionality of the enzyme Neuroscience 142 2006 125 137
    • (2006) Neuroscience , vol.142 , pp. 125-137
    • Studer, F.E.1    Fedele, D.E.2    Marowsky, A.3    Schwerdel, C.4    Wernli, K.5    Vogt, K.6
  • 35
    • 0035066663 scopus 로고    scopus 로고
    • The effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of spinal neurones following carrageenan inflammation and peripheral nerve injury
    • R. Suzuki, L.C. Stanfa, E.A. Kowaluk, M. Williams, M.F. Jarvis, and A.H. Dickenson The effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of spinal neurones following carrageenan inflammation and peripheral nerve injury Br J Pharmacol 132 2001 1615 1623
    • (2001) Br J Pharmacol , vol.132 , pp. 1615-1623
    • Suzuki, R.1    Stanfa, L.C.2    Kowaluk, E.A.3    Williams, M.4    Jarvis, M.F.5    Dickenson, A.H.6
  • 36
    • 79960190061 scopus 로고    scopus 로고
    • Inflammation in diabetic retinopathy
    • J. Tang, and T.S. Kern Inflammation in diabetic retinopathy Prog Retin Eye Res 30 2011 343 358
    • (2011) Prog Retin Eye Res , vol.30 , pp. 343-358
    • Tang, J.1    Kern, T.S.2
  • 37
    • 37349124567 scopus 로고    scopus 로고
    • Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain
    • M.L. Trincavelli, A. Melani, S. Guidi, S. Cuboni, S. Cipriani, and F. Pedata Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain J Neurochem 104 2008 479 490
    • (2008) J Neurochem , vol.104 , pp. 479-490
    • Trincavelli, M.L.1    Melani, A.2    Guidi, S.3    Cuboni, S.4    Cipriani, S.5    Pedata, F.6
  • 38
    • 0034721142 scopus 로고    scopus 로고
    • Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues
    • B.G. Ugarkar, A.J. Castellino, J.M. DaRe, J.J. Kopcho, J.B. Wiesner, and J.M. Schanzer Adenosine kinase inhibitors. 2. Synthesis, enzyme inhibition, and antiseizure activity of diaryltubercidin analogues J Med Chem 43 2000 2894 2905
    • (2000) J Med Chem , vol.43 , pp. 2894-2905
    • Ugarkar, B.G.1    Castellino, A.J.2    Dare, J.M.3    Kopcho, J.J.4    Wiesner, J.B.5    Schanzer, J.M.6
  • 41
    • 0030346281 scopus 로고    scopus 로고
    • Challenges in developing P2 purinoceptor-based therapeutics
    • M. Williams Challenges in developing P2 purinoceptor-based therapeutics Ciba Found Symp 198 1996 309 321
    • (1996) Ciba Found Symp , vol.198 , pp. 309-321
    • Williams, M.1
  • 42
    • 0036584232 scopus 로고    scopus 로고
    • Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42-and lipopolysaccharide activated microglia
    • Z. Xie, M. Wei, T.E. Morgan, P. Fabrizio, D. Han, and C.E. Finch Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42-and lipopolysaccharide activated microglia J Neurosci 22 2002 3484 3492
    • (2002) J Neurosci , vol.22 , pp. 3484-3492
    • Xie, Z.1    Wei, M.2    Morgan, T.E.3    Fabrizio, P.4    Han, D.5    Finch, C.E.6
  • 43
    • 84861022044 scopus 로고    scopus 로고
    • PEDF in diabetic retinopathy: A protective effect of oxidative stress
    • X.F. Zhu, and H.D. Zou PEDF in diabetic retinopathy: A protective effect of oxidative stress J Biomed Biotechnol 2012 580687 580695
    • (2012) J Biomed Biotechnol , pp. 580687-580695
    • Zhu, X.F.1    Zou, H.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.