Picea mariana polyphenolic extract inhibits phlogogenic mediators produced by TNF-α-activated psoriatic keratinocytes: Impact on NF-κB pathway

Journal of Ethnopharmacology

Volumn 151, Issue 1, 2014, Pages 265-278

  García Pérez, Martha Estrella ^a,b   Allaeys, Isabelle ^a   Rusu, Daniel ^a   Pouliot, Roxane ^b   Janezic, Tatjana Stevanovic ^b   Poubelle, Patrice E ^a  

^a University Laval   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

Cytokines; Inflammation; Keratinocytes; Polyphenols; Prostaglandins; Psoriasis

Indexed keywords

ELAFIN; EPIDERMAL GROWTH FACTOR; FRACTALKINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; LACTATE DEHYDROGENASE; NITRIC OXIDE; PICEA MARIANA PLANT EXTRACT; PLANT EXTRACT; POLYPHENOL DERIVATIVE; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLACK SPRUCE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG MECHANISM; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN PHOSPHORYLATION; PSORIASIS VULGARIS;

PICEA MARIANA; PINACEAE;

CYTOKINES; INFLAMMATION; KERATINOCYTES; POLYPHENOLS; PROSTAGLANDINS; PSORIASIS;

CELL SURVIVAL; CELLS, CULTURED; ELAFIN; GENE EXPRESSION REGULATION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; KERATINOCYTES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PICEA; PLANT BARK; PLANT EXTRACTS; PSORIASIS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84891492899     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.10.034     Document Type: Article

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