Analysis of aquaporin expression in liver with a focus on hepatocytes

Histochemistry and Cell Biology

Volumn 144, Issue 4, 2015, Pages 347-363

  Gregoire, Françoise ^a   Lucidi, Valério ^b   Zerrad Saadi, Amal ^a   Virreira, Myrna ^a   Bolaky, Nargis ^a   Delforge, Valérie ^a   Lemmers, Arnaud ^b   Donckier, Vincent ^b   Devière, Jacques ^b   Demetter, Pieter ^b   Perret, Jason ^a   Delporte, Christine ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b ERASME HOSPITAL   (Belgium)

Author keywords

Aquaporin; Gene expression and regulation; Hepatocytes; Human cell line; Liver; Primary culture; Protein localization

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; AQUAPORIN; AQUAPORIN 1; AQUAPORIN 11; AQUAPORIN 3; AQUAPORIN 6; AQUAPORIN 7; AQUAPORIN 8; AQUAPORIN 9; DEXAMETHASONE; FORSKOLIN; GHRELIN; MESSENGER RNA; ROSIGLITAZONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHOLANGIOCYTE; CONTROLLED STUDY; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; KUPFFER CELL; LIVER CELL; MACROPHAGE; NONHUMAN; PRIMARY CULTURE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; ANIMAL; CELL LINE; DRUG EFFECTS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; LIVER; MALE; METABOLISM; MOUSE; PRIMARY CELL CULTURE; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION;

ANIMALS; AQUAPORINS; CELL LINE; ENDOTHELIAL CELLS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HEPATOCYTES; HUMANS; IMMUNOHISTOCHEMISTRY; KUPFFER CELLS; LIVER; MALE; MICE; PRIMARY CELL CULTURE; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSCRIPTION, GENETIC;

EID: 84942368036     PISSN: 09486143     EISSN: 1432119X     Source Type: Journal    
DOI: 10.1007/s00418-015-1341-3     Document Type: Article

References (105)

1. Agre P (2004) Aquaporin water channels (Nobel Lecture). Angew Chem Int Ed Engl 43(33):4278–4290
2. Arsenijevic T, Gregoire F, Delforge V, Delporte C, Perret J (2012) Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis. PLoS ONE 7:e37517
3. Asai M, Higuchi S, Kubota M, Iguchi K, Usui S, Hirano K (2006) Regulators for blood glucose level affect gene expression of aquaporin 3. Biol Pharm Bull 29:991–996
4. Aure MH, Ruus AK, Galtung HK (2014) Aquaporins in the adult mouse submandibular and sublingual salivary glands. J Mol Histol 45:69–80
5. Barazzoni R, Bosutti A, Stebel M, Cattin MR, Roder E, Visintin L, Cattin L, Biolo G, Zanetti M, Guarnieri G (2005a) Ghrelin regulates mitochondrial-lipid metabolism gene expression and tissue fat distribution in liver and skeletal muscle. Am J Physiol 288:E228–E235
6. Barazzoni R, Zanetti M, Biolo G, Guarnieri G (2005b) Metabolic effects of ghrelin and its potential implications in uremia. J Ren Nutr 15:111–115
7. Boltjes A, Movita D, Boonstra A, Woltman AM (2014) The role of Kupffer cells in hepatitis B and hepatitis C virus infections. J Hepatol 61(3):660–671
8. Bustin SA, Benes V, Garson JA, Hellemans J, Huggett J, Kubista M, Mueller R, Nolan T, Pfaffl MW, Shipley GL, Vandesompele J, Wittwer CT (2009) The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin Chem 55:611–622
9. Calamita G, Mazzone A, Bizzoca A, Cavalier A, Cassano G, Thomas D, Svelto M (2001) Expression and immunolocalization of the aquaporin-8 water channel in rat gastrointestinal tract. Eur J Cell Biol 80:711–719
10. Calamita G, Ferri D, Gena P, Liquori GE, Cavalier A, Thomas D, Svelto M (2005a) The inner mitochondrial membrane has aquaporin-8 water channels and is highly permeable to water. J Biol Chem 280:17149–17153
11. Calamita G, Ferri D, Gena P, Liquori GE, Marinelli RA, Meyer G, Portincasa P, Svelto M (2005b) Water transport into bile and role in bile formation. Curr Drug Targets Immune Endocr Metabol Disord 5:137–142
12. Calamita G, Gena P, Meleleo D, Ferri D, Svelto M (2006) Water permeability of rat liver mitochondria: a biophysical study. Biochim Biophys Acta 1758:1018–1024
13. Calamita G, Ferri D, Gena P, Carreras FI, Liquori GE, Portincasa P, Marinelli RA, Svelto M (2008) Altered expression and distribution of aquaporin-9 in the liver of rat with obstructive extrahepatic cholestasis. Am J Physiol Gastrointest 295:G682–G690
14. Calamita G, Gena P, Ferri D, Rosito A, Rojek A, Nielsen S, Marinelli RA, Fruhbeck G, Svelto M (2012) Biophysical assessment of aquaporin-9 as principal facilitative pathway in mouse liver import of glucogenetic glycerol. Biol Cell 104:342–351
15. Caperna TJ, Shannon AE, Richards MP, Garrett WM, Talbot NC (2007) Identification and characterization of aquaporin-9 (AQP9) in porcine hepatic tissue and hepatocytes in monolayer culture. Domest Anim Endocrinol 32:273–286
16. Carbrey JM, Gorelick-Feldman DA, Kozono D, Praetorius J, Nielsen S, Agre P (2003) Aquaglyceroporin AQP9: solute permeation and metabolic control of expression in liver. Proc Natl Acad Sci U S A 100:2945–2950
17. De Vriese C, Delporte C (2007) Autocrine proliferative effect of ghrelin on leukemic HL-60 and THP-1 cells. J Endocrinol 192:199–205
18. De Vriese C, Gregoire F, De Neef P, Robberecht P, Delporte C (2005) Ghrelin is produced by the human erythroleukemic HEL cell line and involved in an autocrine pathway leading to cell proliferation. Endocrinology 146:1514–1522. doi:10.1210/en.2004-0964
19. Delporte C (2012) Recent advances in potential clinical application of ghrelin in obesity. J Obes 2012:535624
20. Delporte C (2013) Structure and physiological actions of ghrelin. Scientifica 2013:518909
21. Dong C, Wang G, Li B, Xiao K, Ma Z, Huang H, Wang X, Bai C (2012) Anti-asthmatic agents alleviate pulmonary edema by upregulating AQP1 and AQP5 expression in the lungs of mice with OVA-induced asthma. Respir Physiol Neurobiol 181:21–28
22. Elkjaer M, Vajda Z, Nejsum LN, Kwon T, Jensen UB, Amiry-Moghaddam M, Frokiaer J, Nielsen S (2000) Immunolocalization of AQP9 in liver, epididymis, testis, spleen, and brain. Biochem Biophys Res Commun 276:1118–1128
23. Elkjaer ML, Nejsum LN, Gresz V, Kwon TH, Jensen UB, Frokiaer J, Nielsen S (2001) Immunolocalization of aquaporin-8 in rat kidney, gastrointestinal tract, testis, and airways. Am J Physiol 281:F1047–F1057
24. Ferri D, Mazzone A, Liquori GE, Cassano G, Svelto M, Calamita G (2003) Ontogeny, distribution, and possible functional implications of an unusual aquaporin, AQP8, in mouse liver. Hepatology 38:947–957
25. Fruci B, Giuliano S, Mazza A, Malaguarnera R, Belfiore A (2013) Nonalcoholic fatty liver: a possible new target for type 2 diabetes prevention and treatment. Int J Mol Sci 14:22933–22966
26. Fukushima M, Kitahara T, Fuse Y, Uno Y, Doot K, Kubo T (2004) Changes in aquaporin expression in the inner ear of the rat after i.p. injection of steroids. Acta Otolaryngol Suppl 553:13–18
27. Garcia F, Kierbel A, Larocca MC, Gradilone SA, Splinter P, LaRusso NF, Marinelli RA (2001) The water channel aquaporin-8 is mainly intracellular in rat hepatocytes, and its plasma membrane insertion is stimulated by cyclic AMP. J Biol Chem 276:12147–12152
28. Goldstein I, Yizhak K, Madar S, Goldfinger N, Ruppin E, Rotter V (2013) p53 promotes the expression of gluconeogenesis-related genes and enhances hepatic glucose production. Cancer Metab 1:9
29. Gradilone SA, Garcia F, Huebert RC, Tietz PS, Larocca MC, Kierbel A, Carreras FI, Larusso NF, Marinelli RA (2003) Glucagon induces the plasma membrane insertion of functional aquaporin-8 water channels in isolated rat hepatocytes. Hepatology 37:1435–1441
30. Gradilone SA, Carreras FI, Lehmann GL, Marinelli RA (2005) Phosphoinositide 3-kinase is involved in the glucagon-induced translocation of aquaporin-8 to hepatocyte plasma membrane. Biol Cell 97:831–836
31. Gu LY, Qiu LW, Chen XF, Lu L, Mei ZC (2014) Oleic acid-induced hepatic steatosis is coupled with downregulation of aquaporin 3 and upregulation of aquaporin 9 via activation of p38 signaling. Horm Metab Res. doi:10.1055/s-0034-1384569
32. Hara-Chikuma M, Verkman AS (2006) Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule. J Am Soc Nephrol 17:39–45
33. Hardie DG, Hawley SA (2001) AMP-activated protein kinase: the energy charge hypothesis revisited. BioEssays 23:1112–1119
34. Hasenour CM, Berglund ED, Wasserman DH (2013) Emerging role of AMP-activated protein kinase in endocrine control of metabolism in the liver. Mol Cell Endocrinol 366:152–162
35. Hayashi Y, Edwards NA, Proescholdt MA, Oldfield EH, Merrill MJ (2007) Regulation and function of aquaporin-1 in glioma cells. Neoplasia 9:777–787
36. Huebert RC, Splinter PL, Garcia F, Marinelli RA, LaRusso NF (2002) Expression and localization of aquaporin water channels in rat hepatocytes. Evidence for a role in canalicular bile secretion. J Biol Chem 277:22710–22717
37. Huebert RC, Jagavelu K, Hendrickson HI, Vasdev MM, Arab JP, Splinter PL, Trussoni CE, Larusso NF, Shah VH (2011) Aquaporin-1 promotes angiogenesis, fibrosis, and portal hypertension through mechanisms dependent on osmotically sensitive microRNAs. Am J Pathol 179:1851–1860
38. Hung KC, Hsieh PM, Hsu CY, Lin CW, Feng GM, Chen YS, Hung CH (2012) Expression of aquaporins in rat liver regeneration. Scand J Gastroenterol 47:676–685
39. Ishibashi K, Tanaka Y, Morishita Y (2014) The role of mammalian superaquaporins inside the cell. Biochim Biophys Acta 1840:1507–1512
40. Itoh A, Tsujikawa T, Fujiyama Y, Bamba T (2003) Enhancement of aquaporin-3 by vasoactive intestinal polypeptide in a human colonic epithelial cell line. J Gastroenterol Hepatol 18:203–210
41. Jiang YJ, Kim P, Lu YF, Feingold KR (2011) PPARgamma activators stimulate aquaporin 3 expression in keratinocytes/epidermis. Exp Dermatol 20:595–599
42. Kahn BB, Alquier T, Carling D, Hardie DG (2005) AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1:15–25
43. Kishida K, Shimomura I, Kondo H, Kuriyama H, Makino Y, Nishizawa H, Maeda N, Matsuda M, Ouchi N, Kihara S, Kurachi Y, Funahashi T, Matsuzawa Y (2001) Genomic structure and insulin-mediated repression of the aquaporin adipose (AQPap), adipose-specific glycerol channel. J Biol Chem 276:36251–36260
44. Kitahara T, Fukushima M, Uno Y, Mishiro Y, Kubo T (2003) Up-regulation of cochlear aquaporin-3 mRNA expression after intra-endolymphatic sac application of dexamethasone. Neurol Res 25:865–870
45. Kola B, Hubina E, Tucci SA, Kirkham TC, Garcia EA, Mitchell SE, Williams LM, Hawley SA, Hardie DG, Grossman AB, Korbonits M (2005) Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. J Biol Chem 280:25196–25201
46. Kolios G, Valatas V, Kouroumalis E (2006) Role of Kupffer cells in the pathogenesis of liver disease. World J Gastroenterol 12:7413–7420
47. Kuriyama H, Shimomura I, Kishida K, Kondo H, Furuyama N, Nishizawa H, Maeda N, Matsuda M, Nagaretani H, Kihara S, Nakamura T, Tochino Y, Funahashi T, Matsuzawa Y (2002) Coordinated regulation of fat-specific and liver-specific glycerol channels, aquaporin adipose and aquaporin 9. Diabetes 51:2915–2921
48. Lebeck J, Ostergard T, Rojek A, Fuchtbauer EM, Lund S, Nielsen S, Praetorius J (2012) Gender-specific effect of physical training on AQP7 protein expression in human adipose tissue. Acta Diabetol 49(Suppl 1):S215–S226
49. Lee DH, Park DB, Lee YK, An CS, Oh YS, Kang JS, Kang SH, Chung MY (2005) The effects of thiazolidinedione treatment on the regulations of aquaglyceroporins and glycerol kinase in OLETF rats. Metabolism 54:1282–1289
50. Liu J, Li H, Nomura K, Ohtake K, Kitagawa T (1992) Frequent spontaneous sister chromatid exchange in hepatocytes of transgenic mice harboring the SV40-T antigen gene. J Cancer Res Clin Oncol 118:601–605
51. Liu Z, Shen J, Carbrey JM, Mukhopadhyay R, Agre P, Rosen BP (2002) Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proc Natl Acad Sci U S A 99:6053–6058
52. Lytle C, Tod TJ, Vo KT, Lee JW, Atkinson RD, Straus DS (2005) The peroxisome proliferator-activated receptor gamma ligand rosiglitazone delays the onset of inflammatory bowel disease in mice with interleukin 10 deficiency. Inflamm Bowel Dis 11:231–243
53. Ma T, Jayaraman S, Wang KS, Song Y, Yang B, Li J, Bastidas JA, Verkman AS (2001) Defective dietary fat processing in transgenic mice lacking aquaporin-1 water channels. Am J Physiol 280:C126–C134
54. Maeda N (2012) Implications of aquaglyceroporins 7 and 9 in glycerol metabolism and metabolic syndrome. Mol Aspects Med 33:665–675
55. Maeda N, Hibuse T, Funahashi T (2009) Role of aquaporin-7 and aquaporin-9 in glycerol metabolism; involvement in obesity. Handb Exp Pharmacol 190:233–249
56. Marchissio MJ, Frances DE, Carnovale CE, Marinelli RA (2012) Mitochondrial aquaporin-8 knockdown in human hepatoma HepG2 cells causes ROS-induced mitochondrial depolarization and loss of viability. Toxicol Appl Pharmacol 264:246–254
57. Marinelli RA, LaRusso NF (1997) Aquaporin water channels in liver: their significance in bile formation. Hepatology 26:1081–1084
58. Marinelli RA, Pham L, Agre P, LaRusso NF (1997) Secretin promotes osmotic water transport in rat cholangiocytes by increasing aquaporin-1 water channels in plasma membrane. Evidence for a secretin-induced vesicular translocation of aquaporin-1. J Biol Chem 272:12984–12988
59. Marinelli RA, Tietz PS, Pham LD, Rueckert L, Agre P, LaRusso NF (1999) Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes. Am J Physiol 276:G280–G286
60. Maruthur NM, Gribble MO, Bennett WL, Bolen S, Wilson LM, Balakrishnan P, Sahu A, Bass E, Kao WH, Clark JM (2014) The pharmacogenetics of type 2 diabetes: a systematic review. Diabetes Care 37:876–886
61. Masyuk AI, LaRusso NF (2006) Aquaporins in the hepatobiliary system. Hepatology 43:S75–S81
62. Masyuk AI, Gong AY, Kip S, Burke MJ, LaRusso NF (2000) Perfused rat intrahepatic bile ducts secrete and absorb water, solute, and ions. Gastroenterology 119:1672–1680
63. Masyuk AI, Masyuk TV, Tietz PS, Splinter PL, LaRusso NF (2002) Intrahepatic bile ducts transport water in response to absorbed glucose. Am J Physiol 283:C785–C791
64. Matsumura Y, Uchida S, Rai T, Sasaki S, Marumo F (1997) Transcriptional regulation of aquaporin-2 water channel gene by cAMP. J Am Soc Nephrol 8:861–867
65. Mennone A, Verkman AS, Boyer JL (2002) Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice. Am J Physiol 283:G739–G746
66. Morishita Y, Matsuzaki T, Hara-chikuma M, Andoo A, Shimono M, Matsuki A, Kobayashi K, Ikeda M, Yamamoto T, Verkman A, Kusano E, Ookawara S, Takata K, Sasaki S, Ishibashi K (2005) Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Mol Cell Biol 25:7770–7779
67. Nielsen S, Smith BL, Christensen EI, Agre P (1993) Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia. Proc Natl Acad Sci U S A 90:7275–7279
68. Nihei K, Koyama Y, Tani T, Yaoita E, Ohshiro K, Adhikary LP, Kurosaki I, Shirai Y, Hatakeyama K, Yamamoto T (2001) Immunolocalization of aquaporin-9 in rat hepatocytes and Leydig cells. Arch Histol Cytol 64:81–88
69. Olszewska M, Bujarski JJ, Kurpisz M (2012) P-bodies and their functions during mRNA cell cycle: mini-review. Cell Biochem Funct 30:177–182
70. Papadopoulos MC, Saadoun S, Verkman AS (2008) Aquaporins and cell migration. Pflugers Arch 456:693–700
71. Patsouris D, Mandard S, Voshol PJ, Escher P, Tan NS, Havekes LM, Koenig W, Marz W, Tafuri S, Wahli W, Muller M, Kersten S (2004) PPARalpha governs glycerol metabolism. J Clin Invest 114:94–103
72. Poling HM, Mohanty SK, Tiao GM, Huppert SS (2014) A comprehensive analysis of aquaporin and secretory related gene expression in neonate and adult cholangiocytes. Gene Expr Patterns 15:96–103
73. Portincasa P, Calamita G (2012) Water channel proteins in bile formation and flow in health and disease: when immiscible becomes miscible. Mol Aspects Med 33:651–664
74. Rabolli V, Wallemme L, Lo Re S, Uwambayinema F, Palmai-Pallag M, Thomassen L, Tyteca D, Octave JN, Marbaix E, Lison D, Devuyst O, Huaux F (2014) Critical role of aquaporins in interleukin 1beta (IL-1beta)-induced inflammation. J Biol Chem 289:13937–13947
75. Rodriguez A, Catalan V, Gomez-Ambrosi J, Garcia-Navarro S, Rotellar F, Valenti V, Silva C, Gil MJ, Salvador J, Burrell MA, Calamita G, Malagon MM, Fruhbeck G (2011) Insulin- and leptin-mediated control of aquaglyceroporins in human adipocytes and hepatocytes is mediated via the PI3 K/Akt/mTOR signaling cascade. J Clin Endocrinol Metab 96:596–597
76. Rodríguez A, Gena P, Méndez-Giménez L, Rosito A, Valentí V, Rotellar F, Sola I, Moncada R, Silva C, Svelto M, Salvador J, Calamita G, Frühbeck G (2014) Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease. Int J Obes 38:1213–1220
77. Rojek AM, Skowronski MT, Fuchtbauer EM, Fuchtbauer AC, Fenton RA, Agre P, Frokiaer J, Nielsen S (2007) Defective glycerol metabolism in aquaporin 9 (AQP9) knockout mice. Proc Natl Acad Sci U S A 104:3609–3614
78. Rojek A, Fuchtbauer EM, Fuchtbauer A, Jelen S, Malmendal A, Fenton RA, Nielsen S (2013) Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feeding. Am J Physiol 304:G501–G515
79. Rump K, Brendt P, Frey UH, Schafer ST, Siffert W, Peters J, Adamzik M (2013) Aquaporin 1 and 5 expression evoked by the beta2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated. Shock 40:430–436
80. Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS (2005a) Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434:786–792
81. Saadoun S, Papadopoulos MC, Watanabe H, Yan D, Manley GT, Verkman AS (2005b) Involvement of aquaporin-4 in astroglial cell migration and glial scar formation. J Cell Sci 118:5691–5698
82. Salt I, Celler JW, Hawley SA, Prescott A, Woods A, Carling D, Hardie DG (1998) AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. Biochem J 334:177–187
83. Seglen PO (1976) Preparation of isolated rat liver cells. Methods Cell Biol 13:29–83
84. Shinkai Y, Sumi D, Toyama T, Kaji T, Kumagai Y (2009) Role of aquaporin 9 in cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes. Toxicol Appl Pharmacol 237:232–236
85. Soria LR, Fanelli E, Altamura N, Svelto M, Marinelli RA, Calamita G (2010) Aquaporin-8-facilitated mitochondrial ammonia transport. Biochem Biophys Res Commun 393:217–221
86. Soria LR, Marrone J, Calamita G, Marinelli RA (2013) Ammonia detoxification via ureagenesis in rat hepatocytes involves mitochondrial aquaporin-8 channels. Hepatology 57:2061–2071
87. Splinter PL, Masyuk AI, LaRusso NF (2003) Specific inhibition of AQP1 water channels in isolated rat intrahepatic bile duct units by small interfering RNAs. J Biol Chem 278:6268–6274
88. Stapleton D, Mitchelhill KI, Gao G, Widmer J, Michell BJ, Teh T, House CM, Fernandez CS, Cox T, Witters LA, Kemp BE (1996) Mammalian AMP-activated protein kinase subfamily. J Biol Chem 271:611–614
89. Tajkhorshid E, Nollert P, Jensen MO, Miercke LJ, O’Connell J, Stroud RM, Schulten K (2002) Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science 296:525–530
90. Talbot NC, Garrett WM, Caperna TJ (2003) Analysis of the expression of aquaporin-1 and aquaporin-9 in pig liver tissue: comparison with rat liver tissue. Cells Tissues Organs 174:117–128
91. Tietz PS, Marinelli RA, Chen XM, Huang B, Cohn J, Kole J, McNiven MA, Alper S, LaRusso NF (2003) Agonist-induced coordinated trafficking of functionally related transport proteins for water and ions in cholangiocytes. J Biol Chem 278:20413–20419
92. Tietz P, Jefferson J, Pagano R, Larusso NF (2005) Membrane microdomains in hepatocytes: potential target areas for proteins involved in canalicular bile secretion. J Lipid Res 46:1426–1432
93. Tran ND, Kim S, Vincent HK, Rodriguez A, Hinton DR, Bullock MR, Young HF (2010) Aquaporin-1-mediated cerebral edema following traumatic brain injury: effects of acidosis and corticosteroid administration. J Neurosurg 112:1095–1104
94. Tyteca D, Nishino T, Debaix H, Van Der Smissen P, N’Kuli F, Hoffmann D, Cnops Y, Rabolli V, van Loo G, Beyaert R, Huaux F, Devuyst O, Courtoy PJ (2015) Regulation of macrophage motility by the water channel aquaporin-1: crucial role of m0/m2 phenotype switch. PLoS ONE 10:e0117398
95. Ueno Y, Alpini G, Yahagi K, Kanno N, Moritoki Y, Fukushima K, Glaser S, LeSage G, Shimosegawa T (2003) Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice. Liver Int 23:449–459
96. van Erpecum KJ, Wang DQ, Moschetta A, Ferri D, Svelto M, Portincasa P, Hendrickx JJ, Schipper M, Calamita G (2006) Gallbladder histopathology during murine gallstone formation: relation to motility and concentrating function. J Lipid Res 47:32–41
97. Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A, Speleman F (2002) Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034
98. Verbavatz JM, Brown D, Sabolic I, Valenti G, Ausiello DA, Van Hoek AN, Ma T, Verkman AS (1993) Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. J Cell Biol 123:605–618
99. Wang W, Zheng M (2011) Nuclear factor kappa B pathway down-regulates aquaporin 5 in the nasal mucosa of rats with allergic rhinitis. Eur Arch Otorhinolaryngol 268:73–81
100. Xiong X, Miao J, Xi Z, Zhang H, Han B, Hu Y (2005) Regulatory effect of dexamethasone on aquaporin-1 expression in cultured bovine trabecular meshwork cells. J Huazhong Univ Sci Technol Med Sci 25:735–737
101. Yang B, Song Y, Zhao D, Verkman AS (2005) Phenotype analysis of aquaporin-8 null mice. Am J Physiol 288:C1161–C1170
102. Yang B, Zhao D, Solenov E, Verkman AS (2006) Evidence from knockout mice against physiologically significant aquaporin 8-facilitated ammonia transport. Am J Physiol 291:C417–C423
103. Yokomori H, Oda M, Yoshimura K, Kaneko F, Hibi T (2011) Aquaporin-1 associated with hepatic arterial capillary proliferation on hepatic sinusoid in human cirrhotic liver. Liver Int 31:1554–1564
104. Yokoyama Y, Iguchi K, Usui S, Hirano K (2011) AMP-activated protein kinase modulates the gene expression of aquaporin 9 via forkhead box a2. Arch Biochem Biophys 515:80–88
105. Zhu N, Feng X, He C, Gao H, Yang L, Ma Q, Guo L, Qiao Y, Yang H, Ma T (2011) Defective macrophage function in aquaporin-3 deficiency. FASEB J 25:4233–4239