Efficient production of free fatty acids from soybean meal carbohydrates

Biotechnology and Bioengineering

Volumn 112, Issue 11, 2015, Pages 2324-2333

  Wang, Dan ^a,b   Thakker, Chandresh ^c   Liu, Ping ^a   Bennett, George N ^c   San, Ka Yiu ^a  

^a Rice University   (United States)

^b CHONGQING UNIVERSITY   (China)

^c RICE UNIVERSITY   (United States)

Author keywords

Catabolite repression; Escherichia coli; Free fatty acids; Mixed sugars; Soybean meal hydrolysate

Indexed keywords

CARBOHYDRATES; ENZYMATIC HYDROLYSIS; ESCHERICHIA COLI; FEEDSTOCKS; FERMENTATION; FRUCTOSE; GLUCOSE; HYDROLYSIS; MIXTURES; SUGARS;

BIOMASS FEEDSTOCK; CATABOLITE REPRESSION; ENZYMATIC TREATMENTS; FREE FATTY ACID; RENEWABLE FEEDSTOCKS; SOLUBLE CARBOHYDRATES; SOYBEAN MEAL; VALUE-ADDED CHEMICALS;

FATTY ACIDS;

ACYL ACP THIOESTERASE; CARBOHYDRATE DERIVATIVE; FATTY ACID; FRUCTOSE; GLUCOSE; GLUCOSE TRANSPORTER; HYDROLYASE; HYDROXYACYL ACP DEHYDRATASE; SUGAR; THIOL ESTER HYDROLASE; UNCLASSIFIED DRUG; CARBOHYDRATE;

ANIMAL CELL; ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; BIOMASS PRODUCTION; CATABOLISM; CELL DENSITY; CELL METABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ESCHERICHIA COLI; FATTY ACID SYNTHESIS; FERMENTATION; GENE REPRESSION; HYDROLYSIS; NONHUMAN; PLASMID; RENEWABLE ENERGY; SOYBEAN MEAL; BIOTRANSFORMATION; CARBOHYDRATE METABOLISM; CHEMISTRY; GENETICS; ISOLATION AND PURIFICATION; METABOLIC ENGINEERING; METABOLISM; PROCEDURES; SOYBEAN;

BIOTRANSFORMATION; CARBOHYDRATE METABOLISM; CARBOHYDRATES; ESCHERICHIA COLI; FATTY ACIDS, NONESTERIFIED; METABOLIC ENGINEERING; METABOLIC NETWORKS AND PATHWAYS; PLASMIDS; SOYBEANS;

EID: 84942367020     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.25633     Document Type: Article

References (46)

1. Andersson C, Hodge D, Berglund KA, Rova U. 2007. Effect of different carbon sources on the production of succinic acid using metabolically engineered Escherichia coli. Biotechnol Progr 23:381-388.
2. Balzer G, Thakker C, Bennett GN, San KY. 2013. Metabolic engineering Escherichia coli to minimize byproduct formate and improving succinate productivity through NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase. Metab Eng 20:1-8.
3. Cao Y, Yang J, Xian M, Xu X, Liu W. 2010. Increasing unsaturated fatty acid contents in Escherichia coli by coexpression of three different genes. Appl Microbiol Biotechnol 87:271-280.
4. Cho H, Cronan J, Jr. 1995. Defective export of a periplasmic enzyme disrupts regulation of fatty acid synthesis. J Biol Chem 270:4216-4219.
5. Datsenko KA, Wanner BL. 2000. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc Nat Acad Sci 97:6640-6645.
6. Dellomonaco C, Clomburg JM, Miller EN, Gonzalez R. 2011. Engineering reversal of the β-oxidation cycle for the synthesis of fuels and chemicals. Nature 476:355-359.
7. Dien BS, Nichols NN, Bothast RJ. 2002. Fermentation of sugar mixtures using Escherichia coli catabolite repression mutants engineered for production of L-lactate acid. J Ind Microbiol Biotechnol 29:221-227.
8. Eldridge AC, Black LT, Wolf JW. 1979. Carbohydrate composition of soybean flours, protein concentrates, and isolates. J Agric Food Chem 27:799-802.
9. Feng Y, Cronan JE. 2011. Complex binding of the FabR repressor of bacterial unsaturated fatty acid biosynthesis to its cognate promoters. Mol Microbiol 80:195-218.
10. Fridjonssson O, Watzlawick H, Gehweiler A, Rohrhirsch T, Mattes R. 1999. Cloning of the gene encoding a novel thermostable galactosidase from Thermus brockianus I TI360. Appl Environ Microbiol 65:3955-3963.
11. Giannoccaro E, Wang YJ, Chen P. 2006. Effects of solvent, temperature, time, solvent-to-sample ratio, sample size, and defatting on the extraction of soluble sugars in soybean. J Food Sci 71:C59-C64.
12. Janßen HJ, Steinbüchel A. 2014. Fatty acid synthesis in Escherichia coli and its applications towards the production of fatty acid based biofuels. Biotechnol Biofuels 7:7-33.
13. Jiang P, Cronan J, Jr. 1994. Inhibition of fatty acid synthesis in Escherichia coli in the absence of phospholipid synthesis and release of inhibition by thioesterase action. J Bacteriol 176:2814-2821.
14. Jönsson L, Alriksson B, Nilvebrant N. 2013. Bioconversion of lignocelluloses: Inhibitors and detoxification. Biotechnol Biofuels 6:16-25.
15. Karr-Lilienthal LK, Grieshop CM, Spears JK, Fahey GC. 2005. Amino acid, carbohydrate, and fat composition of soybean meals prepared at 55 commercial U.S. soybean processing plants. J Agric Food Chem 53:2146-2150.
16. Kim JH, Block DE, Mills DA. 2010. Simultaneous consumption of pentose and hexose sugars: An optimal microbial phenotype for efficient fermentation of lignocellulosic biomass. Appl Microbiol Biotechnol 88:1077-1085.
17. Kim KR, Oh DK. 2013. Production of hydroxyl fatty acids by microbial fatty acid-hydroxylation enzymes. Biotechnol Adv 31:1473-1485.
18. Kim NJ, Li H, Jung K, Chang HN, Lee PC. 2011. Ethanol production from algal hydrolysates using Escherichia coli KO11. Bioresour Technol 102:7466-7469.
19. Lennen R, Braden G, West R, Dumesic J, Pfleger B. 2010. A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes. Biotechnol Bioeng 106:193-202.
20. Li M, Zhang X, Agrawal A, San K. 2012. Effect of acetate formation pathway and long chain fatty acid CoA-ligase on the free fatty acid production in E. coli expressing acyl-ACP thioesterase from Ricinus communis. Metab Eng 14:380-387.
21. Lin H, Bennett GN, San K. 2005. Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield. Metab Eng 7:116-127.
22. Liu K. 1997. Soybeans: Chemistry, technology, and utilization. New York: Chapman and Hall.
23. Liu T, Vora H, Khosla C. 2010. Quantitative analysis and engineering of fatty acid biosynthesis in E. coli. Metab Eng 12:378-386.
24. Lu X, Vora H, Khosla C. 2008. Overexpression of free fatty acids in E. coli: Implications for biodiesel production. Metab Eng 10:333-339.
25. L-Lactate production from seaweed hydrolysate of Laminaria japonica using metabolically engineered Escherichia coli. Appl Biochem Biotechnol 172:1938-1952.
26. McCue L, Thompson W, Carmack C, Ryan MP, Liu JS, Derbyshire V, Lawrence CE. 2001. Phylogenetic footprinting of transcription factor binding sites in proteobacterial genomes. Nucleic Acids Res 29:774-782.
27. Nickolau B, Perera M, Brachova L, Shanks B. 2008. Platform chemicals for a biorenewable chemical industry. Plant J 54:536-545.
28. O'Fallon JV, Busboom JR, Nelson ML, Gaskins CT. 2007. A direct method for fatty acid methyl ester synthesis: Application to wet meat tissues, oils, and feedstuffs. J Anim Sci 85:1511-1521.
29. Ooi S, Pee H. 1985. Processing for industrial fatty acids-II. J Am Oil Chem Soc 62:348-351.
30. Peralta-Yahya PB, Zhang F, del Cardayre SB, Keasling JD. 2012. Microbial engineering for the production of advanced biofuels. Nature 488:320-328.
31. San KY, Li M. 2013. Bacteria and method for synthesizing fatty acids. Vol. WO/2013/059218, USA.
32. Sánchez AM, Bennett GN, San K. 2005. Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity. Metab Eng 7:229-239.
33. Schmid K, Schupfner M, Schmitt R. 1982. Plasmid-mediated uptake and metabolism of sucrose by Escherichia coli K-12. J Bacteriol 151:68-76.
34. Schmid K, Schmitt R. 1976. Raffinose metabolism in Escherichia coli K12. Purification and properties of a new a-galactosidase specified by a transmissible plasmid. Eur. J Biochem 67:95-104.
35. Shimizu K. 2013. Metabolic regulation of a bacterial cell system with emphasis on Escherichia coli metabolism. ISRN Biochem 645983:1-47.
36. Stephanopoulos G. 2007. Challenges in engineering microbes for biofuels production. Science 315:801-804.
37. Thakker C, San K, Bennett GN. 2013. Production of succinic acid by engineered E. coli strains using soybean carbohydrates as feedstock under aerobic fermentation conditions. Bioresour Technol 130:398-405.
38. Voelker T, Davies H. 1994. Alteration of the specificity and regulation of fatty acid synthesis of Escherichia coli by expression of plant medium-chain acyl-acyl carrier protein thioesterase. J Bacteriol 176:7320-7327.
39. Wang D, Li Q, Yang M, Zhang Y, Su Z, Xing J. 2011. Efficient production of succinic acid from corn stalk hydrolysates by a recombinant Escherichia coli with ptsG mutation. Process Biochem 46:365-371.
40. Wu H, San KY. 2014. Efficient odd straight medium chain free fatty acid production by metabolically engineered Escherichia coli. Biotechnol Bioeng 9999:1-11.
41. Wu H, Lee J, Karanjikar M, San KY. 2014a. Efficient free fatty acid production from woody biomass hydrolysate using metabolically engineered Escherichia coli. Bioresour Technol 169:119-125.
42. Wu H, Karanjikar M, San KY. 2014b. Metabolic engineering of Escherichia coli for efficient free fatty acid production from glycerol. Metab Eng 25:82-91.
43. Zha Y, Muilwijk B, Coulier L, Punt PJ. 2012. Inhibitory compounds in lignocellulosic biomass hydrolysates during hydrolysate fermentation process. J Bioprocess Biotechniq 2:1-11.
44. Zhang XJ, Li M, Agrawal A, San KY. 2011. Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterase. Metab Eng 13:713-722.
45. Zhang YM, Marrakchi H, Rock CO. 2002. The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli. J Biol Chem 277:15558-15565.
46. Zhang YM, Rock CO. 2009. Transcriptional regulation in bacterial membrane lipid synthesis. J Lipid Res 50:S115-S119.