Incorporation of fibrin into a collagen-glycosaminoglycan matrix results in a scaffold with improved mechanical properties and enhanced capacity to resist cell-mediated contraction

Acta Biomaterialia

Volumn 26, Issue , 2015, Pages 205-214

  Brougham, Claire M ^a,b   Levingstone, Tanya J ^a,c   Jockenhoevel, Stefan ^d   Flanagan, Thomas C ^e   O'Brien, Fergal J ^a,c  

^a ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Cardiovascular scaffold; Fibrin; Heart valve; Tissue engineering

Indexed keywords

BIOMATERIALS; BIOMECHANICS; CELL ENGINEERING; CELLS; CYTOLOGY; GELS; MUSCLE; REINFORCEMENT; SCAFFOLDS (BIOLOGY); TENSILE TESTING;

% REDUCTIONS; CARDIOVASCULAR SCAFFOLD; COLLAGEN-GLYCOSAMINOGLYCAN MATRICES; FIBRIN; GLYCOSAMINOGLYCANS; HEART VALVES; IN-VIVO; TISSUE ENGINEERING SCAFFOLD; TISSUES ENGINEERINGS; VIVO STUDIES;

COLLAGEN;

COLLAGEN; FIBRIN; GLYCOSAMINOGLYCAN; BIOMIMETIC MATERIAL;

ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TISSUE SCAFFOLD; VASCULAR SMOOTH MUSCLE CELL; CELL CULTURE; CELL LINE; CHEMISTRY; COMPRESSIVE STRENGTH; CYTOLOGY; DEVICE FAILURE ANALYSIS; DEVICES; EQUIPMENT DESIGN; EXTRACELLULAR MATRIX; MATERIALS TESTING; MECHANICAL STRESS; MUSCLE CONTRACTION; PHYSIOLOGY; SMOOTH MUSCLE CELL; SYNTHESIS; TENSILE STRENGTH; TISSUE ENGINEERING; YOUNG MODULUS;

BIOMIMETIC MATERIALS; CELL LINE; CELLS, CULTURED; COLLAGEN; COMPRESSIVE STRENGTH; ELASTIC MODULUS; EQUIPMENT DESIGN; EQUIPMENT FAILURE ANALYSIS; EXTRACELLULAR MATRIX; FIBRIN; GLYCOSAMINOGLYCANS; HUMANS; MATERIALS TESTING; MUSCLE CONTRACTION; MYOCYTES, SMOOTH MUSCLE; STRESS, MECHANICAL; TENSILE STRENGTH; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84942294403     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.08.022     Document Type: Article

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