Engineering vessel-like networks within multicellular fibrin-based constructs

Biomaterials

Volumn 32, Issue 31, 2011, Pages 7856-7869

  Lesman, Ayelet ^a   Koffler, Jacob ^a   Atlas, Roee ^b   Blinder, Yaron J ^a   Kam, Zvi ^c   Levenberg, Shulamit ^a  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b Weizmann Science Park   (Israel)

^c WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Angiogenesis; Cell encapsulation; Co culture; Endothelial cell; Fibrin; Scaffold

Indexed keywords

ANGIOGENESIS; CELL ENCAPSULATION; CELL SEEDING; CELL TYPES; COCULTURE; ENGINEERED TISSUES; FIBRIN; FIBRIN GELS; FIBRIN MATRIX; FIBRINOGEN CONCENTRATION; FIBROBLAST CELLS; IN-VITRO; IN-VIVO; MATURITY LEVELS; MYOBLAST CELLS; NEOVASCULARIZATION; NETWORK FORMATION; PLLA; POLY L LACTIC ACID; SYNTHETIC SCAFFOLDS; TIME POINTS; VASCULARIZATION;

BIOMATERIALS; CONFOCAL MICROSCOPY; ENDOTHELIAL CELLS; FIBROBLASTS; LACTIC ACID; THREE DIMENSIONAL; TISSUE;

CELL CULTURE;

FIBRIN; FIBRINOGEN; MOLECULAR SCAFFOLD; POLYGLACTIN; POLYLACTIC ACID;

ANGIOGENESIS; ANIMAL EXPERIMENT; ARTICLE; CELL DIFFERENTIATION; CELL ENCAPSULATION; CELL STRUCTURE; ENDOTHELIUM CELL; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMAGING; IMMUNOFLUORESCENCE TEST; IMPLANTATION; IN VITRO STUDY; MALE; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TISSUE ENGINEERING; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION;

ANIMALS; BLOOD VESSEL PROSTHESIS; CELL DIFFERENTIATION; CELLS; CELLS, CULTURED; ENDOTHELIAL CELLS; FIBRIN; FIBROBLASTS; HUMANS; MICE; MICROSCOPY, CONFOCAL; MYOBLASTS; NEOVASCULARIZATION, PHYSIOLOGIC; PERFUSION; THROMBIN; TIME FACTORS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 80051825164     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2011.07.003     Document Type: Article

References (38)

1. Brey E.M., Uriel S., Greisler H.P., McIntire L.V. Therapeutic neovascularization: contributions from bioengineering. Tissue Eng 2005, 11:567-584.
2. Kaully T., Kaufman-Francis K., Lesman A., Levenberg S. Vascularization-the conduit to viable engineered tissues. Tissue Eng Part B Rev 2009, 15:159-169.
3. Laschke M.W., Harder Y., Amon M., Martin I., Farhadi J., Ring A., et al. Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng 2006, 12:2093-2104.
4. Levenberg S., Rouwkema J., Macdonald M., Garfein E.S., Kohane D.S., Darland D.C., et al. Engineering vascularized skeletal muscle tissue. Nat Biotechnol 2005, 23:879-884.
5. Caspi O., Lesman A., Basevitch Y., Gepstein A., Arbel G., Habib I.H., et al. Tissue engineering of vascularized cardiac muscle from human embryonic stem cells. Circ Res 2007, 100:263-272.
6. Koike N., Fukumura D., Gralla O., Au P., Schechner J.S., Jain R.K. Tissue engineering: creation of long-lasting blood vessels. Nature 2004, 428:138-139.
7. Jain R.K., Au P., Tam J., Duda D.G., Fukumura D. Engineering vascularized tissue. Nat Biotechnol 2005, 23:821-823.
8. Ding R., Darland D.C., Parmacek M.S., D'Amore P.A. Endothelial-mesenchymal interactions in vitro reveal molecular mechanisms of smooth muscle/pericyte differentiation. Stem Cells Dev 2004, 13:509-520.
9. Kunz-Schughart L.A., Schroeder J.A., Wondrak M., van Rey F., Lehle K., Hofstaedter F., et al. Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro. Am J Physiol Cell Physiol 2006, 290:C1385-C1398.
10. Stevens K.R., Kreutziger K.L., Dupras S.K., Korte F.S., Regnier M., Muskheli V., et al. Physiological function and transplantation of scaffold-free and vascularized human cardiac muscle tissue. Proc Natl Acad Sci U S A 2009, 106:16568-16573.
11. Brutsaert D.L. Cardiac endothelial-myocardial signaling: its role in cardiac growth, contractile performance, and rhythmicity. Physiol Rev 2003, 83:59-115.
12. Cleaver O., Melton D.A. Endothelial signaling during development. Nat Med 2003, 9:661-668.
13. Lesman A., Habib M., Caspi O., Gepstein A., Arbel G., Levenberg S., et al. Transplantation of a tissue-engineered human vascularized cardiac muscle. Tissue Eng Part A 2010, 16:115-125.
14. Chen X., Aledia A.S., Ghajar C.M., Griffith C.K., Putnam A.J., Hughes C.C., et al. Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature. Tissue Eng Part A 2009, 15:1363-1371.
15. Discher D.E., Janmey P., Wang Y.L. Tissue cells feel and respond to the stiffness of their substrate. Science 2005, 310:1139-1143.
16. Engler A.J., Sen S., Sweeney H.L., Discher D.E. Matrix elasticity directs stem cell lineage specification. Cell 2006, 126:677-689.
17. Levy-Mishali M., Zoldan J., Levenberg S. Effect of scaffold stiffness on myoblast differentiation. Tissue Eng Part A 2009, 15:935-944.
18. Lutolf M.P., Gilbert P.M., Blau H.M. Designing materials to direct stem-cell fate. Nature 2009, 462:433-441.
19. Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005, 23:47-55.
20. van Hinsbergh V.W., Collen A., Koolwijk P. Role of fibrin matrix in angiogenesis. Ann N Y Acad Sci 2001, 936:426-437.
21. Levenberg S., Huang N.F., Lavik E., Rogers A.B., Itskovitz-Eldor J., Langer R. Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc Natl Acad Sci U S A 2003, 100:12741-12746.
22. Holder W.D., Gruber H.E., Moore A.L., Culberson C.R., Anderson W., Burg K.J., et al. Cellular ingrowth and thickness changes in poly-L-lactide and polyglycolide matrices implanted subcutaneously in the rat. J Biomed Mater Res 1998, 41:412-421.
23. Lichtenstein N., Geiger B., Kam Z. Quantitative analysis of cytoskeletal organization by digital fluorescent microscopy. Cytometry A 2003, 54:8-18.
24. McNees A.L., White Z.S., Zanwar P., Vilchez R.A., Butel J.S. Specific and quantitative detection of human polyomaviruses BKV, JCV, and SV40 by real time PCR. J Clin Virol 2005, 34:52-62.
25. Yuan C.C., Miley W., Waters D. A quantification of human cells using an ERV-3 real time PCR assay. J Virol Methods 2001, 91:109-117.
26. Singh K., Moyer H., Williams J.K., Schwartz Z., Boyan B.D. Fibrin Glue: A Scaffold for Cellular-Based Therapy in a Critical-Sized Defect. Ann Plast Surg 2011, 66:301-305.
27. Ahmed T.A., Giulivi A., Griffith M., Hincke M. Fibrin glues in combination with mesenchymal stem cells to develop a tissue-engineered cartilage substitute. Tissue Eng Part A 2011, 17:323-335.
28. Christman K.L., Vardanian A.J., Fang Q., Sievers R.E., Fok H.H., Lee R.J. Injectable fibrin scaffold improves cell transplant survival, reduces infarct expansion, and induces neovasculature formation in ischemic myocardium. J Am Coll Cardiol 2004, 44:654-660.
29. Xu J.W., Zaporojan V., Peretti G.M., Roses R.E., Morse K.B., Roy A.K., et al. Injectable tissue-engineered cartilage with different chondrocyte sources. Plast Reconstr Surg 2004, 113:1361-1371.
30. Montano I., Schiestl C., Schneider J., Pontiggia L., Luginbuhl J., Biedermann T., et al. Formation of human capillaries in vitro: the engineering of prevascularized matrices. Tissue Eng Part A 2010, 16:269-282.
31. Peters M.C., Polverini P.J., Mooney D.J. Engineering vascular networks in porous polymer matrices. J Biomed Mater Res 2002, 60:668-678.
32. Dado D., Levenberg S. Cell-scaffold mechanical interplay within engineered tissue. Semin Cell Dev Biol 2009, 20:656-664.
33. Yamamura N., Sudo R., Ikeda M., Tanishita K. Effects of the mechanical properties of collagen gel on the in vitro formation of microvessel networks by endothelial cells. Tissue Eng 2007, 13:1443-1453.
34. Urbich C., Dimmeler S. Endothelial progenitor cells: characterization and role in vascular biology. Circ Res 2004, 95:343-353.
35. Tsopanoglou N.E., Maragoudakis M.E. Thrombin's central role in angiogenesis and pathophysiological processes. Eur Cytokine Netw 2009, 20:171-179.
36. Wang B., Pearson T., Manning G., Donnelly R. In vitro study of thrombin on tubule formation and regulators of angiogenesis. Clin Appl Thromb Hemost 2010, 16:674-678.
37. Leor J., Tuvia S., Guetta V., Manczur F., Castel D., Willenz U., et al. Intracoronary injection of in situ forming alginate hydrogel reverses left ventricular remodeling after myocardial infarction in Swine. J Am Coll Cardiol 2009, 54:1014-1023.
38. Cassell O.C., Morrison W.A., Messina A., Penington A.J., Thompson E.W., Stevens G.W., et al. The influence of extracellular matrix on the generation of vascularized, engineered, transplantable tissue. Ann N Y Acad Sci 2001, 944:429-442.