Tubular heart valves from decellularized engineered tissue

Annals of Biomedical Engineering

Volumn 41, Issue 12, 2013, Pages 2645-2654

  Syedain, Zeeshan H ^a   Meier, Lee A ^a   Reimer, Jay M ^a   Tranquillo, Robert T ^a  

^a University of Minnesota   (United States)

Author keywords

Decellularization; Heart valve; Pulse duplicator; Tissue engineering

Indexed keywords

BIOMECHANICS; BIOREACTORS; CELL CULTURE; DETERIORATION; FATIGUE TESTING; HEART; MECHANICAL PROPERTIES; ORIFICES; PRESSURE GRADIENT; TISSUE ENGINEERING; VALVES (MECHANICAL);

DECELLULARIZATION; DECELLULARIZED TISSUES; EFFECTIVE ORIFICE AREAS; HEART VALVES; PULSE DUPLICATOR; TENSILE MECHANICAL PROPERTIES; TISSUE-ENGINEERED HEART; TRANSVALVULAR PRESSURE GRADIENTS;

TISSUE;

COLLAGEN; FIBRIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANISOTROPY; AORTA FLOW; ARTICLE; CELL INFILTRATION; DETERIORATION; FATIGUE; FIBROBLAST; GEL; HEART VALVE; HEART VALVE REPLACEMENT; HOST CELL; LUNG PRESSURE; NONHUMAN; PRESSURE GRADIENT; PULMONARY VALVE; SHEEP; SYSTOLE; TISSUE ENGINEERED HEART VALVE; TISSUE ENGINEERING;

ANIMALS; HEART VALVES; SHEEP; STRESS, MECHANICAL; TENSILE STRENGTH; TISSUE ENGINEERING;

EID: 84896723077     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0872-9     Document Type: Article

References (35)

1. Baaijens, F., C. Bouten, S. Hoerstrup, A. Mol, N. Driessen, and R. Boerboom. Functional tissue engineering of the aortic heart valve. Clin. Hemorheol. Microcirc. 33:197-199, 2005.
2. Christie, G. W. Anatomy of aortic heart valve leaflets: the influence of glutaraldehyde fixation on function. Eur. J. Cardiothorac. Surg. 6:S25-S32, 1992.
3. Christie, G. W., and B. G. Barratt-Boyes. Mechanical properties of porcine pulmonary valve leaflets: how do they differ from aortic leaflets? Ann. Thorac. Surg. 60:S195-S199, 1995.
4. Cox, J. L., N. Ad, K. Myers, M. Gharib, and R. C. Quijano. Tubular heart valves: a new tissue prosthesis design-preclinical evaluation of the 3F aortic bioprosthesis. J. Thorac. Cardiovasc. Surg. 130:520-527, 2005.
5. Dahl, S. L., A. P. Kypson, J. H. Lawson, J. L. Blum, J. T. Strader, Y. Li, R. J. Manson, W. E. Tente, L. DiBernardo, M. T. Hensley, R. Carter, T. P. Williams, H. L. Prichard, M. S. Dey, K. G. Begelman, and L. E. Niklason. Readily available tissue-engineered vascular grafts. Sci. Transl. Med. 3:68ra69, 2011.
6. Dijkman, P. E., A. Driessen-Mol, L. M. de Heer, J. Kluin, L. A. van Herwerden, B. Odermatt, F. P. Baaijens, and S. P. Hoerstrup. Trans-apical versus surgical implantation of autologous ovine tissue-engineered heart valves. J. Heart Valve Dis. 21:670-678, 2012.
7. Dijkman, P. E., A. Driessen-Mol, L. Frese, S. P. Hoerstrup, and F. P. Baaijens. Decellularized homologous tissue-engineered heart valves as off-the-shelf alternatives to xeno-and homografts. Biomaterials 33:4545-4554, 2012.
8. Emmert, M. Y., B. Weber, L. Behr, T. Frauenfelder, C. E. Brokopp, J. Grunenfelder, V. Falk, and S. P. Hoerstrup. Transapical aortic implantation of autologous marrow stromal cell-based tissue-engineered heart valves: first experiences in the systemic circulation. JACC. Cardiovasc. Interv. 4:822-823, 2011.
9. Flanagan, T. C., C. Cornelissen, S. Koch, B. Tschoeke, J. S. Sachweh, T. Schmitz-Rode, and S. Jockenhoevel. The in vitro development of autologous fibrin-based tissue-engineered heart valves through optimised dynamic conditioning. Biomaterials 28:3388-3397, 2007.
10. Flanagan, T. C., J. S. Sachweh, J. Frese, H. Schnoring, N. Gronloh, S. Koch, R. H. Tolba, T. Schmitz-Rode, and S. Jockenhoevel. In vivo remodeling and structural characterization of fibrin-based tissue-engineered heart valves in the adult sheep model. Tissue Eng. A 15:2965-2976, 2009.
11. Gerosa, G., V. Tarzia, G. Rizzoli, and T. Bottio. Small aortic annulus: the hydrodynamic performances of 5 commercially available tissue valves. J. Thorac. Cardiovasc. Surg. 131:1058-1064, 2006.
12. Grassl, E. D., T. R. Oegema, and R. T. Tranquillo. A fibrin-based arterial media equivalent. J. Biomed. Mater. Res. A 66A:550-561, 2003.
13. Hoerstrup, S. P., R. Sodian, S. Daebritz, J. Wang, E. A. Bacha, D. P. Martin, A. M. Moran, K. J. Guleserian, J. S. Sperling, S. Kaushal, J. P. Vacanti, F. J. Schoen, and J. E. Mayer Jr. Functional living trileaflet heart valves grown in vitro. Circulation 102:III44-III49, 2000.
14. Isenberg, B. C., and R. T. Tranquillo. Long-term cyclic distention enhances the mechanical properties of collagen-based media-equivalents. Ann. Biomed. Eng. 31:937-949, 2003.
15. Kim, Y. J., R. L. Sah, J. Y. Doong, and A. J. Grodzinsky. Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal. Biochem. 174:168-176, 1988.
16. Nakayama, Y., Y. Yahata, M. Yamanami, T. Tajikawa, K. Ohba, K. Kanda, and H. Yaku. A completely autologous valved conduit prepared in the open form of trileaflets (type VI biovalve): mold design and valve function in vitro. J. Biomed. Mater. Res. B Appl. Biomater. 99:135-141, 2011.
17. Neidert, M. R., and R. T. Tranquillo. Tissue-engineered valves with commissural alignment. Tissue Eng. 12:891-903, 2006.
18. Quint, C., Y. Kondo, R. J. Manson, J. H. Lawson, A. Dardik, and L. E. Niklason. Decellularized tissue-engineered blood vessel as an arterial conduit. Proc. Natl. Acad. Sci. U. S. A. 108:9214-9219, 2011.
19. Robinson, P. S., S. L. Johnson, M. C. Evans, V. H. Barocas, and R. T. Tranquillo. Functional tissue-engineered valves from cell-remodeled fibrin with commissural alignment of cell-produced collagen. Tissue Eng. A 14:83-95, 2008.
20. Rouleau, L., D. Tremblay, R. Cartier, R. Mongrain, and R. L. Leask. Regional variations in canine descending aortic tissue mechanical properties change with formalin fixation. Cardiovasc. Pathol. 21:390-397, 2012.
21. Schmidt, D., P. E. Dijkman, A. Driessen-Mol, R. Stenger, C. Mariani, A. Puolakka, M. Rissanen, T. Deichmann, B. Odermatt, B. Weber, M. Y. Emmert, G. Zund, F. P. Baaijens, and S. P. Hoerstrup. Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells. J. Am. Coll. Cardiol. 56:510-520, 2010.
22. Shinoka, T., C. K. Breuer, R. E. Tanel, G. Zund, T. Miura, P. X. Ma, R. Langer, J. P. Vacanti, and J. E. Mayer Jr. Tissue engineering heart valves: valve leaflet replacement study in a lamb model. Ann. Thorac. Surg. 60:S513-S516, 1995.
23. Sodian, R., S. P. Hoerstrup, J. S. Sperling, S. Daebritz, D. P. Martin, A. M. Moran, B. S. Kim, F. J. Schoen, J. P. Vacanti, and J. E. Mayer Jr. Early in vivo experience with tissue-engineered trileaflet heart valves. Circulation 102:III22-III29, 2000.
24. Stegemann, H., and K. Stalder. Determination of hydroxyproline. Clin. Chim. Acta 18:267-273, 1967.
25. Stradins, P., R. Lacis, I. Ozolanta, B. Purina, V. Ose, L. Feldmane, and V. Kasyanov. Comparison of biomechanical and structural properties between human aortic and pulmonary valve. Eur. J. Cardiothorac. Surg. 26:634-639, 2004.
26. Syedain, Z. H., A. R. Bradee, S. Kren, D. A. Taylor, and R. T. Tranquillo. Decellularized tissue-engineered heart valve leaflets with recellularization potential. Tissue Eng. A 19:759-769, 2013.
27. Syedain, Z., M. T. Lahti, S. Johnson, P. Robinson, G. R. Ruth, R. Bianco, and R. Tranquillo. Implantation of a tissue engineered heart valve from human fibroblasts exhibiting short term function in the sheep pulmonary artery. Cardiovasc. Eng. Technol. 2:101-112, 2011.
28. Syedain, Z. H., L. A. Meier, J. W. Bjork, A. Lee, and R. T. Tranquillo. Implantable arterial grafts from human fibroblasts and fibrin using a multi-graft pulsed flow-stretch bioreactor with noninvasive strength monitoring. Biomaterials 32:714-722, 2011.
29. Syedain, Z. H., L. Meier, M. Lahti, S. Johnson, and R. T. Tranquillo. Implantation of completely biological, aligned engineered arteries pre-made from allogeneic fibroblasts in a sheep model. 2013 (submitted).
30. Syedain, Z. H., and R. T. Tranquillo. Controlled cyclic stretch bioreactor for tissue-engineered heart valves. Biomaterials 30:4078-4084, 2009.
31. Syedain, Z. H., and R. T. Tranquillo. TGF-beta1 diminishes collagen production during long-term cyclic stretching of engineered connective tissue: implication of decreased ERK signaling. J. Biomech. 44:848-855, 2011.
32. Syedain, Z. H., J. S. Weinberg, and R. T. Tranquillo. Cyclic distension of fibrin-based tissue constructs: evidence of adaptation during growth of engineered connective tissue. Proc. Natl. Acad. Sci. U. S. A. 105:6537-6542, 2008.
33. Tower, T. T., M. R. Neidert, and R. T. Tranquillo. Fiber alignment imaging during mechanical testing of soft tissues. Ann. Biomed. Eng. 30:1221-1233, 2002.
34. Weber, B., J. Scherman, M. Y. Emmert, J. Gruenenfelder, R. Verbeek, M. Bracher, M. Black, J. Kortsmit, T. Franz, R. Schoenauer, L. Baumgartner, C. Brokopp, I. Agarkova, P. Wolint, G. Zund, V. Falk, P. Zilla, and S. P. Hoerstrup. Injectable living marrow stromal cell-based autologous tissue engineered heart valves: first experiences with a one-step intervention in primates. Eur. Heart J. 32:2830-2840, 2011.
35. Williams, C., S. L. Johnson, P. S. Robinson, and R. T. Tranquillo. Cell sourcing and culture conditions for fibrin-based valve constructs. Tissue Eng. 12:1489-1502, 2006.