Effect of biodegradation and de novo matrix synthesis on the mechanical properties of valvular interstitial cell-seeded polyglycerol sebacate-polycaprolactone scaffolds

Acta Biomaterialia

Volumn 9, Issue 4, 2013, Pages 5963-5973

  Sant, Shilpa ^a,b,c   Iyer, Dharini ^a,b,c   Gaharwar, Akhilesh K ^b,c   Patel, Alpesh ^a,b   Khademhosseini, Ali ^a,b,c  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Fibrous scaffolds; Heart valve tissue engineering; In vitro degradation; Polycaprolactone; Polyglycerol sebacate

Indexed keywords

BIOMECHANICS; CELLS; CYTOLOGY; DEGRADATION; HEART; POLYCAPROLACTONE; PROTEINS; SCAFFOLDS (BIOLOGY); SCANNING ELECTRON MICROSCOPY; SODIUM HYDROXIDE; THERMOANALYSIS; TISSUE; VALVES (MECHANICAL);

ACELLULAR SCAFFOLDS; FIBROUS SCAFFOLDS; HEART VALVE TISSUE ENGINEERINGS; HEART VALVES; INTERSTITIALS; MATRIX SYNTHESIS; POLYCAPROLACTONE SCAFFOLDS; POLYGLYCEROL SEBACATE; POLYGLYCEROLS; SEBACATE;

BIODEGRADATION;

POLYCAPROLACTONE; POLYGLYCEROL SEBACATE; SEBACIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BIODEGRADATION; CELL PROLIFERATION; CELL SPREADING; CELL VIABILITY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; EXTRACELLULAR MATRIX; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MECHANICS; PRIORITY JOURNAL; PROTEIN SECRETION; SCANNING ELECTRON MICROSCOPY; SYNTHESIS; THERMAL ANALYSIS; TISSUE ENGINEERING;

EID: 84875370093     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.11.014     Document Type: Article

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