Lupeol derivative mitigates Echis carinatus venom-induced tissue destruction by neutralizing venom toxins and protecting collagen and angiogenic receptors on inflammatory cells

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 12, 2015, Pages 2393-2409

  Katkar, G D ^a   Sharma, Rachana D ^a   Vishalakshi, G J ^a   Naveenkumar, S K ^a   Madhur, Gaurav ^b   Thushara, R M ^a   Narender, T ^b   Girish, K S ^a   Kemparaju, K ^a  

^a UNIVERSITY OF MYSORE   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Collagen receptors; E. carinatus; Inflammatory cells; Local toxicity; Lupeol; Venom

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; COLLAGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; LUPEOL; SNAKE VENOM; TUMOR NECROSIS FACTOR ALPHA; CELL SURFACE RECEPTOR; PENTACYCLIC TRITERPENE; VENOM ANTISERUM; VIPER VENOM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLEEDING; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG STRUCTURE; ECHIS CARINATUS; EDEMA; ENVENOMATION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY CELL; MOUSE; MUSCLE CELL; MUSCLE DISEASE; MUSCLE NECROSIS; MYOTOXICITY; NONHUMAN; OXIDATIVE STRESS; POISONOUS SNAKE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SKIN NECROSIS; ANIMAL; DRUG EFFECTS; MALE; METABOLISM; NEOVASCULARIZATION (PATHOLOGY);

ANIMALS; ANTIVENINS; COLLAGEN; HUMANS; MALE; NEOVASCULARIZATION, PATHOLOGIC; PENTACYCLIC TRITERPENES; RECEPTORS, CELL SURFACE; VIPER VENOMS;

EID: 84942284128     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.09.011     Document Type: Article

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