Novel apigenin based small molecule that targets snake venom metalloproteases

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Srinivasa, Venkatachalaiah ^a   Sundaram, Mahalingam S ^b   Anusha, Sebastian ^a   Hemshekhar, Mahadevappa ^b   Nayaka, Siddaiah Chandra ^b   Kemparaju, Kempaiah ^b   Basappa, ^a   Girish, Kesturu S ^b,c   Rangappa, Kanchugarakoppal S ^b  

^a BANGALORE UNIVERSITY   (India)

^b UNIVERSITY OF MYSORE   (India)

^c TUMKUR UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APIGENIN DERIVATIVE; FIBRIN; FIBRINOGEN; METALLOPROTEINASE; SNAKE VENOM; SNAKE VENOM METALLOPROTEINASE; UNCLASSIFIED DRUG; APIGENIN; BOTHROPASIN, BOTHROPS JARARACA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING; BLOOD CLOTTING TIME; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG RESPONSE; DRUG STRUCTURE; DRUG SYNTHESIS; ECHIS CARINATUS; EDEMA; ENVENOMATION; FIBRINOGENOLYSIS; IN VIVO STUDY; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOUSE; MUSCLE DISEASE; MUSCLE NECROSIS; MYOTOXICITY; NONHUMAN; TISSUE NECROSIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENZYMOLOGY; HEMORRHAGE; METABOLISM; PATHOLOGY; SNAKE BITES; SYNTHESIS; VIPERIDAE;

ANIMALS; APIGENIN; CROTALID VENOMS; FIBRIN; FIBRINOGEN; HEMORRHAGE; METALLOENDOPEPTIDASES; METALLOPROTEASES; MICE; MOLECULAR DOCKING SIMULATION; SNAKE BITES; SNAKE VENOMS; VIPERIDAE;

EID: 84906968537     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106364     Document Type: Article

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