Tuning the predictive capacity of the PAMPA-BBB model

European Journal of Pharmaceutical Sciences

Volumn 79, Issue , 2015, Pages 53-60

  Müller, Judit ^a   Esso, Katalin ^b   Dargó, Gergo ^a   Könczöl, Árpád ^c   Balogh, György T ^c  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b Institute of Data Analytics and Information Systems   (Hungary)

^c GEDEON RICHTER LTD   (Hungary)

Author keywords

Blood brain barrier; Cholesterol; Cosolvent; Lipid composition; PAMPA; Permeability

Indexed keywords

ACETYLSALICYLIC ACID; AMFEBUTAMONE; AMITRIPTYLINE; BUSPIRONE; CARBAMAZEPINE; CHOLESTEROL; CLOZAPINE; DESIPRAMINE; DIAZEPAM; DICLOFENAC; DIMETHYL SULFOXIDE; DIPHENHYDRAMINE; FENTANYL; FLUOXETINE; HYDROCORTISONE; HYDROXYZINE; IMIPRAMINE; INDOMETACIN; LAMOTRIGINE; MAPROTILINE; MEMBRANE LIPID; NORTRIPTYLINE; OXAZEPAM; PHENYTOIN; PROGESTERONE; PROMAZINE; PROPRANOLOL; QUETIAPINE; SOLVENT; UNINDEXED DRUG; ARTIFICIAL MEMBRANE;

APPARENT PERMEABILITY; ARTICLE; ASSAY; BLOOD BRAIN BARRIER; BLOOD BRAIN BARRIER SPECIFIC PARALLEL ARTIFICIAL MEMBRANE PERMEABILITY ASSAY; DIFFUSION; DRUG PENETRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INCUBATION TEMPERATURE; INCUBATION TIME; LIPID MEMBRANE; LIPOPHILICITY; MEMBRANE PERMEABILITY; MICROPLATE READER; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; RADIATION ABSORPTION; ULTRAVIOLET RADIATION; ARTIFICIAL MEMBRANE; BIOLOGICAL MODEL; CACO 2 CELL LINE; HUMAN; METABOLISM; PERMEABILITY; PHARMACOKINETICS;

BLOOD-BRAIN BARRIER; CACO-2 CELLS; HUMANS; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; PERMEABILITY; PHARMACOKINETICS;

EID: 84942239841     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2015.08.019     Document Type: Article

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