-
3
-
-
84942326846
-
Independent emergence of Plasmodium falciparum artemisinin resistance mutations in Southeast Asia
-
Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, et al. Independent emergence of Plasmodium falciparum artemisinin resistance mutations in Southeast Asia. J Infect Dis. 2015;211:670-9. http://dx.doi.org/10.1093/infdis/ jiu491
-
(2015)
J Infect Dis
, vol.211
, pp. 670-679
-
-
Takala-Harrison, S.1
Jacob, C.G.2
Arze, C.3
Cummings, M.P.4
Silva, J.C.5
Dondorp, A.M.6
-
4
-
-
84904892931
-
Spread of artemisinin resistance in Plasmodium falciparum malaria
-
Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014;371:411-23. http://dx.doi.org/10.1056/NEJMoa1314981
-
(2014)
N Engl J Med
, vol.371
, pp. 411-423
-
-
Ashley, E.A.1
Dhorda, M.2
Fairhurst, R.M.3
Amaratunga, C.4
Lim, P.5
Suon, S.6
-
5
-
-
84925354867
-
Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: A cross-sectional survey of the K13 molecular marker
-
Tun KM, Imwong M, Lwin KM, Win AA, Hlaing TM, Hlaing T, et al. Spread of artemisinin-resistant Plasmodium falciparum in Myanmar: a cross-sectional survey of the K13 molecular marker. Lancet Infect Dis. 2015;15:415-21. http://dx.doi.org/10.1016/ S1473-3099(15)70032-0
-
(2015)
Lancet Infect Dis
, vol.15
, pp. 415-421
-
-
Tun, K.M.1
Imwong, M.2
Lwin, K.M.3
Win, A.A.4
Hlaing, T.M.5
Hlaing, T.6
-
6
-
-
84924080547
-
Genetic architecture of artemisinin-resistant Plasmodium falciparum
-
Miotto O, Amato R, Ashley EA, MacInnis B, Almagro-Garcia J, Amaratunga C, et al. Genetic architecture of artemisinin-resistant Plasmodium falciparum. Nat Genet. 2015;47:226-34. http://dx.doi.org/10.1038/ng.3189
-
(2015)
Nat Genet
, vol.47
, pp. 226-234
-
-
Miotto, O.1
Amato, R.2
Ashley, E.A.3
MacInnis, B.4
Almagro-Garcia, J.5
Amaratunga, C.6
-
7
-
-
80755159531
-
Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast
-
Borrmann S, Sasi P, Mwai L, Bashraheil M, Abdallah A, Muriithi S, et al. Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast. PLoS ONE. 2011;6:e26005. http://dx.doi.org/ 10.1371/journal.pone.0026005
-
(2011)
PLoS ONE
, vol.6
-
-
Borrmann, S.1
Sasi, P.2
Mwai, L.3
Bashraheil, M.4
Abdallah, A.5
Muriithi, S.6
-
8
-
-
84890319200
-
Evidence of an increased incidence of day 3 parasitaemia in Suriname: An indicator of the emerging resistance of Plasmodium falciparum to artemether
-
Vreden SG, Jitan JK, Bansie RD, Adhin MR. Evidence of an increased incidence of day 3 parasitaemia in Suriname: an indicator of the emerging resistance of Plasmodium falciparum to artemether. Mem Inst Oswaldo Cruz. 2013;108:968-73. http://dx.doi.org/10.1590/0074-0276130167
-
(2013)
Mem Inst Oswaldo Cruz
, vol.108
, pp. 968-973
-
-
Vreden, S.G.1
Jitan, J.K.2
Bansie, R.D.3
Adhin, M.R.4
-
9
-
-
77951220629
-
Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism
-
Witkowski B, Lelievre J, Barragan MJ, Laurent V, Su XZ, Berry A, et al. Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism. Antimicrob Agents Chemother. 2010;54:1872-7. http://dx.doi.org/10.1128/ AAC.01636-09
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 1872-1877
-
-
Witkowski, B.1
Lelievre, J.2
Barragan, M.J.3
Laurent, V.4
Su, X.Z.5
Berry, A.6
-
10
-
-
84892372929
-
A molecular marker of artemisinin resistant Plasmodium falciparum malaria
-
Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, et al. A molecular marker of artemisinin resistant Plasmodium falciparum malaria. Nature. 2014;505:50-5. http://dx.doi.org/10.1038/nature12876
-
(2014)
Nature
, vol.505
, pp. 50-55
-
-
Ariey, F.1
Witkowski, B.2
Amaratunga, C.3
Beghain, J.4
Langlois, A.C.5
Khim, N.6
-
11
-
-
84872858923
-
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia
-
Witkowski B, Khim N, Chim P, Kim S, Ke S, Kloeung N, et al. Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia. Antimicrob Agents Chemother. 2013;57:914-23. http://dx.doi.org/10.1128/AAC.01868-12
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 914-923
-
-
Witkowski, B.1
Khim, N.2
Chim, P.3
Kim, S.4
Ke, S.5
Kloeung, N.6
-
12
-
-
84887622121
-
Novel phenotypic assays for the detection of artemisininresistant Plasmodium falciparum malaria in Cambodia: In-vitro and ex-vivo drug-response studies
-
Witkowski B, Amaratunga C, Khim N, Sreng S, Chim P, Kim S, et al. Novel phenotypic assays for the detection of artemisininresistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies. Lancet Infect Dis. 2013;13:1043-9. http://dx.doi.org/10.1016/S1473-3099(13)70252-4
-
(2013)
Lancet Infect Dis
, vol.13
, pp. 1043-1049
-
-
Witkowski, B.1
Amaratunga, C.2
Khim, N.3
Sreng, S.4
Chim, P.5
Kim, S.6
-
13
-
-
84921719133
-
K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
-
Straimer J, Gnadig NF, Witkowski B, Amaratunga C, Duru V, Ramadani AP, et al. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates. Science. 2015;347:428-31. http://dx.doi.org/10.1126/science.1260867
-
(2015)
Science
, vol.347
, pp. 428-431
-
-
Straimer, J.1
Gnadig, N.F.2
Witkowski, B.3
Amaratunga, C.4
Duru, V.5
Ramadani, A.P.6
-
14
-
-
84905373498
-
Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro
-
Amaratunga C, Witkowski B, Dek D, Try V, Khim N, Miotto O, et al. Plasmodium falciparum founder populations in western Cambodia have reduced artemisinin sensitivity in vitro. Antimicrob Agents Chemother. 2014;58:4935-7. http://dx.doi.org/ 10.1128/AAC.03055-14
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4935-4937
-
-
Amaratunga, C.1
Witkowski, B.2
Dek, D.3
Try, V.4
Khim, N.5
Miotto, O.6
-
15
-
-
84900838464
-
Artemisinin resistance in Plasmodium falciparum
-
Amaratunga C, Witkowski B, Khim N, Menard D, Fairhurst RM. Artemisinin resistance in Plasmodium falciparum. Lancet Infect Dis. 2014;14:449-50. http://dx.doi.org/10.1016/ S1473-3099(14)70777-7
-
(2014)
Lancet Infect Dis
, vol.14
, pp. 449-450
-
-
Amaratunga, C.1
Witkowski, B.2
Khim, N.3
Menard, D.4
Fairhurst, R.M.5
-
16
-
-
77955628762
-
Persister cells
-
Lewis K. Persister cells. Annu Rev Microbiol. 2010;64:357-72. http://dx.doi.org/10.1146/annurev.micro.112408.134306
-
(2010)
Annu Rev Microbiol
, vol.64
, pp. 357-372
-
-
Lewis, K.1
-
17
-
-
0025078793
-
Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and β-lactam antimicrobial agents
-
Wolfson JS, Hooper DC, Mchugh GL, Bozza MA, Swartz MN. Mutants of Escherichia coli K-12 exhibiting reduced killing by both quinolone and β-lactam antimicrobial agents. Antimicrob Agents Chemother. 1990;34:1938-43. http://dx.doi.org/10.1128/ AAC.34.10.1938
-
(1990)
Antimicrob Agents Chemother
, vol.34
, pp. 1938-1943
-
-
Wolfson, J.S.1
Hooper, D.C.2
McHugh, G.L.3
Bozza, M.A.4
Swartz, M.N.5
-
18
-
-
0020590028
-
hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis
-
Moyed HS, Bertrand KP. hipA, a newly recognized gene of Escherichia coli K-12 that affects frequency of persistence after inhibition of murein synthesis. J Bacteriol. 1983;155:768-75.
-
(1983)
J Bacteriol
, vol.155
, pp. 768-775
-
-
Moyed, H.S.1
Bertrand, K.P.2
-
19
-
-
84857698357
-
Evidence for the contribution of the hemozoin synthesis pathway of the murine Plasmodium yoelii to the resistance to artemisinin-related drugs
-
Witkowski B, Lelievre J, Nicolau-Travers ML, Iriart X, Njomnang Soh P, Bousejra-Elgarah F, et al. Evidence for the contribution of the hemozoin synthesis pathway of the murine Plasmodium yoelii to the resistance to artemisinin-related drugs. PLoS ONE. 2012;7:e32620. http://dx.doi.org/10.1371/ journal.pone.0032620
-
(2012)
PLoS ONE
, vol.7
-
-
Witkowski, B.1
Lelievre, J.2
Nicolau-Travers, M.L.3
Iriart, X.4
Njomnang Soh, P.5
Bousejra-Elgarah, F.6
-
20
-
-
34247126868
-
Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes
-
Benoit-Vical F, Lelievre J, Berry A, Deymier C, Dechy-Cabaret O, Cazelles J, et al. Trioxaquines are new antimalarial agents active on all erythrocytic forms, including gametocytes. Antimicrob Agents Chemother. 2007;51:1463-72. http://dx.doi.org/10.1128/ AAC.00967-06
-
(2007)
Antimicrob Agents Chemother
, vol.51
, pp. 1463-1472
-
-
Benoit-Vical, F.1
Lelievre, J.2
Berry, A.3
Deymier, C.4
Dechy-Cabaret, O.5
Cazelles, J.6
-
21
-
-
0018606732
-
Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique
-
Desjardins RE, Canfield CJ, Haynes JD, Chulay JD. Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique. Antimicrob Agents Chemother. 1979;16:710-8. http://dx.doi.org/10.1128/AAC.16.6.710
-
(1979)
Antimicrob Agents Chemother
, vol.16
, pp. 710-718
-
-
Desjardins, R.E.1
Canfield, C.J.2
Haynes, J.D.3
Chulay, J.D.4
-
22
-
-
79960964039
-
"Persisters": Survival at the cellular level
-
Dawson CC, Intapa C, Jabra-Rizk MA. "Persisters": survival at the cellular level. PLoS Pathog. 2011;7:e1002121. http://dx.doi.org/10.1371/journal.ppat.1002121
-
(2011)
PLoS Pathog
, vol.7
-
-
Dawson, C.C.1
Intapa, C.2
Jabra-Rizk, M.A.3
-
23
-
-
84905386385
-
Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum
-
Chen N, LaCrue AN, Teuscher F, Waters NC, Gatton ML, Kyle DE, et al. Fatty acid synthesis and pyruvate metabolism pathways remain active in dihydroartemisinin-induced dormant ring stages of Plasmodium falciparum. Antimicrob Agents Chemother. 2014;58:4773-81. http://dx.doi.org/10.1128/AAC.02647-14
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4773-4781
-
-
Chen, N.1
LaCrue, A.N.2
Teuscher, F.3
Waters, N.C.4
Gatton, M.L.5
Kyle, D.E.6
-
24
-
-
84921785363
-
Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
-
Mok S, Ashley EA, Ferreira PE, Zhu L, Lin Z, Yeo T, et al. Drug resistance. Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance. Science. 2015;347:431-5. http://dx.doi.org/10.1126/ science.1260403
-
(2015)
Science
, vol.347
, pp. 431-435
-
-
Mok, S.1
Ashley, E.A.2
Ferreira, P.E.3
Zhu, L.4
Lin, Z.5
Yeo, T.6
-
25
-
-
77957858201
-
Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression
-
Veiga MI, Ferreira PE, Schmidt BA, Ribacke U, Bjorkman A, Tichopad A, et al. Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression. PLoS ONE. 2010;5:e12408. http://dx.doi.org/ 10.1371/journal.pone.0012408
-
(2010)
PLoS ONE
, vol.5
-
-
Veiga, M.I.1
Ferreira, P.E.2
Schmidt, B.A.3
Ribacke, U.4
Bjorkman, A.5
Tichopad, A.6
-
26
-
-
84872853616
-
Mefloquine exposure induces cell cycle delay and reveals stage-specific expression of the pfmdr1 gene
-
Bohórquez EB, Juliano JJ, Kim HS, Meshnick SR. Mefloquine exposure induces cell cycle delay and reveals stage-specific expression of the pfmdr1 gene. Antimicrob Agents Chemother. 2013;57:833-9. http://dx.doi.org/10.1128/AAC.01006-12
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 833-839
-
-
Bohórquez, E.B.1
Juliano, J.J.2
Kim, H.S.3
Meshnick, S.R.4
-
27
-
-
84939540007
-
Mitochondrial membrane potential in a small subset of artemisinin-induced dormant Plasmodium falciparum parasites in vitro
-
Peatey CL, Chavchich M, Chen N, Gresty KJ, Gray KA, Gatton ML, et al. Mitochondrial membrane potential in a small subset of artemisinin-induced dormant Plasmodium falciparum parasites in vitro. J Infect Dis. 2015;212:426-34. http://dx.doi.org/ 10.1093/infdis/jiv048
-
(2015)
J Infect Dis
, vol.212
, pp. 426-434
-
-
Peatey, C.L.1
Chavchich, M.2
Chen, N.3
Gresty, K.J.4
Gray, K.A.5
Gatton, M.L.6
-
28
-
-
1842533231
-
Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum
-
Sijwali PS, Rosenthal PJ. Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum. Proc Natl Acad Sci U S A. 2004;101:4384-9. http://dx.doi.org/10.1073/pnas.0307720101
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 4384-4389
-
-
Sijwali, P.S.1
Rosenthal, P.J.2
-
29
-
-
79960992639
-
Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion
-
Klonis N, Crespo-Ortiz MP, Bottova I, Abu-Bakar N, Kenny S, Rosenthal PJ, et al. Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion. Proc Natl Acad Sci U S A. 2011;108:11405-10. http://dx.doi.org/10.1073/pnas.1104063108
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11405-11410
-
-
Klonis, N.1
Crespo-Ortiz, M.P.2
Bottova, I.3
Abu-Bakar, N.4
Kenny, S.5
Rosenthal, P.J.6
-
30
-
-
0031847073
-
Quinoline antimalarials: Mechanisms of action and resistance and prospects for new agents
-
Foley M, Tilley L. Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents. Pharmacol Ther. 1998;79:55-87. http://dx.doi.org/10.1016/S0163-7258(98)00012-6
-
(1998)
Pharmacol Ther
, vol.79
, pp. 55-87
-
-
Foley, M.1
Tilley, L.2
-
31
-
-
26444465676
-
The antimalarial drug artemisinin alkylates heme in infected mice
-
Robert A, Benoit-Vical F, Claparols C, Meunier B. The antimalarial drug artemisinin alkylates heme in infected mice. Proc Natl Acad Sci U S A. 2005;102:13676-80. http://dx.doi.org/ 10.1073/pnas.0500972102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 13676-13680
-
-
Robert, A.1
Benoit-Vical, F.2
Claparols, C.3
Meunier, B.4
-
32
-
-
84921906716
-
Polymorphisms in K13 and falcipain-2 associated with artemisinin resistance are not prevalent in Plasmodium falciparum isolated from Ugandan children
-
Conrad MD, Bigira V, Kapisi J, Muhindo M, Kamya MR, Havlir DV, et al. Polymorphisms in K13 and falcipain-2 associated with artemisinin resistance are not prevalent in Plasmodium falciparum isolated from Ugandan children. PLoS ONE. 2014;9:e105690. http://dx.doi.org/10.1371/ journal.pone.0105690
-
(2014)
PLoS ONE
, vol.9
-
-
Conrad, M.D.1
Bigira, V.2
Kapisi, J.3
Muhindo, M.4
Kamya, M.R.5
Havlir, D.V.6
-
33
-
-
84926654867
-
Molecular assessment of artemisinin resistance markers, polymorphisms in the K13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar
-
Nyunt MH, Hlaing T, Oo HW, Tin-Oo LL, Phway HP, Wang B, et al. Molecular assessment of artemisinin resistance markers, polymorphisms in the K13 propeller, and a multidrug-resistance gene in the eastern and western border areas of Myanmar. Clin Infect Dis. 2015;60:1208-15. http://dx.doi.org/10.1093/cid/ciu1160
-
(2015)
Clin Infect Dis
, vol.60
, pp. 1208-1215
-
-
Nyunt, M.H.1
Hlaing, T.2
Oo, H.W.3
Tin-Oo, L.L.4
Phway, H.P.5
Wang, B.6
-
34
-
-
84926625655
-
K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa
-
Kamau E, Campino S, Amenga-Etego L, Drury E, Ishengoma D, Johnson K, et al. K13-propeller polymorphisms in Plasmodium falciparum parasites from sub-Saharan Africa. J Infect Dis. 2015;211:1352-5.
-
(2015)
J Infect Dis
, vol.211
, pp. 1352-1355
-
-
Kamau, E.1
Campino, S.2
Amenga-Etego, L.3
Drury, E.4
Ishengoma, D.5
Johnson, K.6
-
35
-
-
84904861610
-
Dihydroartemisininpiperaquine failure in Cambodia
-
Saunders DL, Vanachayangkul P, Lon C. Dihydroartemisininpiperaquine failure in Cambodia. N Engl J Med. 2014;371:484-5. http://dx.doi.org/10.1056/NEJMc1403007
-
(2014)
N Engl J Med
, vol.371
, pp. 484-485
-
-
Saunders, D.L.1
Vanachayangkul, P.2
Lon, C.3
|