Antimalarial exposure delays Plasmodium falciparum intra-erythrocytic cycle and drives drug transporter genes expression

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Veiga, Maria Isabel ^a,b   Ferreira, Pedro Eduardo ^a,b   Schmidt, Berit Aydin ^a   Ribacke, Ulf ^a   Björkman, Anders ^a   Tichopad, Ales ^c,d   Gil, José Pedro ^a,b,e  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF ALGARVE   (Portugal)

^c INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e BINGHAMTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; MEFLOQUINE; PLASMODIUM FALCIPARUM CHLOROQUINE RESISTANCE TRANSPORTER; PROTEIN PFMDR1; PROTEIN PFMRP1; PROTEIN PFMRP2; UNCLASSIFIED DRUG; ANTIMALARIAL AGENT; ARTEMISININ; ARTEMISININ DERIVATIVE; MESSENGER RNA; PROTOZOAL PROTEIN;

ANTIMALARIAL DRUG SUSCEPTIBILITY; ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE REGULATION; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC TRAIT; GENETIC VARIABILITY; IC 50; MATHEMATICAL MODEL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMODIUM FALCIPARUM; PROTIST LIFE CYCLE STAGE; RNA SEQUENCE; CELL CYCLE; CYTOLOGY; DRUG COMBINATION; ERYTHROCYTE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

EUKARYOTA; PLASMODIUM FALCIPARUM;

ANTIMALARIALS; ARTEMISININS; CELL CYCLE; DRUG THERAPY, COMBINATION; ERYTHROCYTES; GENE EXPRESSION REGULATION; MEFLOQUINE; MEMBRANE TRANSPORT PROTEINS; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RNA, MESSENGER;

EID: 77957858201     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012408     Document Type: Article

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