Titanium dioxide nanoparticles trigger loss of function and perturbation of mitochondrial dynamics in primary hepatocytes

PLoS ONE

Volumn 10, Issue 8, 2015, Pages

  Natarajan, Vaishaali ^a   Wilson, Christina L ^a   Hayward, Stephen L ^a   Kidambi, Srivatsan ^a,b  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; MANGANESE SUPEROXIDE DISMUTASE; NANOMATERIAL; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; TITANIUM DIOXIDE; UREA; METAL NANOPARTICLE; SUPEROXIDE DISMUTASE; TITANIUM;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FOOD INTAKE; HEALTH HAZARD; IN VITRO STUDY; IN VIVO STUDY; INGESTION; LIVER CELL; LIVER FUNCTION; MALE; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE POTENTIAL; MOTIVATION; NONHUMAN; PARTICLE SIZE; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; RAT; TOXICITY; UREA CYCLE; ANIMAL; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; METABOLISM; MITOCHONDRION; OXIDATIVE STRESS; PHOTON CORRELATION SPECTROSCOPY; SPRAGUE DAWLEY RAT;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DYNAMIC LIGHT SCATTERING; HEPATOCYTES; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; METAL NANOPARTICLES; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; OXIDATIVE STRESS; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; TITANIUM;

EID: 84941892385     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0134541     Document Type: Article

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