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Volumn 5, Issue , 2015, Pages

A spheroid toxicity assay using magnetic 3D bioprinting and real-time mobile device-based imaging

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; DODECYL SULFATE SODIUM; PENICILLIN G; TRANSCRIPTOME;

EID: 84941711757     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep13987     Document Type: Article
Times cited : (117)

References (51)
  • 1
    • 77955785233 scopus 로고    scopus 로고
    • Integration of in silico and in vitro platforms for pharmacokinetic-pharmacodynamic modeling
    • Sung, J. H., Esch, M. B. & Shuler, M. L. Integration of in silico and in vitro platforms for pharmacokinetic-pharmacodynamic modeling. Expert Opin. Drug Metab. Toxicol. 6, 1063-81 (2010).
    • (2010) Expert Opin. Drug Metab. Toxicol. , vol.6 , pp. 1063-1081
    • Sung, J.H.1    Esch, M.B.2    Shuler, M.L.3
  • 2
    • 84862775836 scopus 로고    scopus 로고
    • Paradigm shift in toxicity testing and modeling
    • Sun, H., Xia, M., Austin, C. P. & Huang, R. Paradigm shift in toxicity testing and modeling. AAPS J. 14, 473-80 (2012).
    • (2012) AAPS J. , vol.14 , pp. 473-480
    • Sun, H.1    Xia, M.2    Austin, C.P.3    Huang, R.4
  • 3
    • 0742305697 scopus 로고    scopus 로고
    • Beyond the Petri dish
    • Zhang, S. Beyond the Petri dish. Nat. Biotechnol. 22, 151-2 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 151-152
    • Zhang, S.1
  • 4
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman, E., Pankov, R., Stevens, D. R. & Yamada, K. M. Taking cell-matrix adhesions to the third dimension. Science 294, 1708-12 (2001).
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 5
    • 34648834682 scopus 로고    scopus 로고
    • The third dimension bridges the gap between cell culture and live tissue
    • Pampaloni, F., Reynaud, E. G. & Stelzer, E. H. K. The third dimension bridges the gap between cell culture and live tissue. Nat. Rev. Mol. Cell Biol. 8, 839-845 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 839-845
    • Pampaloni, F.1    Reynaud, E.G.2    Stelzer, E.H.K.3
  • 7
    • 77958497531 scopus 로고    scopus 로고
    • Immunotoxicity and immunogenicity of biopharmaceuticals: Design concepts and safety assessment
    • Bhogal, N. Immunotoxicity and immunogenicity of biopharmaceuticals: design concepts and safety assessment. Curr. Drug Saf. 5, 293-307 (2010).
    • (2010) Curr. Drug Saf. , vol.5 , pp. 293-307
    • Bhogal, N.1
  • 8
    • 80053925801 scopus 로고    scopus 로고
    • Cell-matrix adhesions in 3D
    • Harunaga, J. S. & Yamada, K. M. Cell-matrix adhesions in 3D. Matrix Biol. 30, 363-8 (2011).
    • (2011) Matrix Biol. , vol.30 , pp. 363-368
    • Harunaga, J.S.1    Yamada, K.M.2
  • 9
    • 0042358985 scopus 로고    scopus 로고
    • Cell culture: Biologys new dimension
    • Abbott, A. Cell culture: biologys new dimension. Nature 424, 870-2 (2003).
    • (2003) Nature , vol.424 , pp. 870-872
    • Abbott, A.1
  • 10
    • 0023093713 scopus 로고
    • Multicellular spheroids. A review on cellular aggregates in cancer research
    • Mueller-Klieser, W. Multicellular spheroids. A review on cellular aggregates in cancer research. J. Cancer Res. Clin. Oncol. 113, 101-22 (1987).
    • (1987) J. Cancer Res. Clin. Oncol. , vol.113 , pp. 101-122
    • Mueller-Klieser, W.1
  • 11
    • 77953916745 scopus 로고    scopus 로고
    • Multicellular tumor spheroids: An underestimated tool is catching up again
    • Hirschhaeuser, F., et al. Multicellular tumor spheroids: an underestimated tool is catching up again. J. Biotechnol. 148, 3-15 (2010).
    • (2010) J. Biotechnol. , vol.148 , pp. 3-15
    • Hirschhaeuser, F.1
  • 12
    • 84858723379 scopus 로고    scopus 로고
    • Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
    • Vinci, M., et al. Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation. BMC Biol. 10, 29 (2012).
    • (2012) BMC Biol. , vol.10 , pp. 29
    • Vinci, M.1
  • 13
    • 78751560396 scopus 로고    scopus 로고
    • High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array
    • Tung, Y.-C., et al. High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array. Analyst 136, 473-8 (2011).
    • (2011) Analyst , vol.136 , pp. 473-478
    • Tung, Y.-C.1
  • 14
    • 77049124474 scopus 로고    scopus 로고
    • Modelling tissues in 3D: The next future of pharmaco-toxicology and food research?
    • Mazzoleni, G., Di Lorenzo, D. & Steimberg, N. Modelling tissues in 3D: the next future of pharmaco-toxicology and food research? Genes Nutr. 4, 13-22 (2009).
    • (2009) Genes Nutr. , vol.4 , pp. 13-22
    • Mazzoleni, G.1    Di Lorenzo, D.2    Steimberg, N.3
  • 15
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-based drug screen: Considerations and practical approach
    • Friedrich, J., Seidel, C., Ebner, R. & Kunz-Schughart, L. A. Spheroid-based drug screen: considerations and practical approach. Nat. Protoc. 4, 309-24 (2009).
    • (2009) Nat. Protoc. , vol.4 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3    Kunz-Schughart, L.A.4
  • 16
    • 79959877538 scopus 로고    scopus 로고
    • The validated embryonic stem cell test to predict embryotoxicity in vitro
    • Seiler, A. E. M. & Spielmann, H. The validated embryonic stem cell test to predict embryotoxicity in vitro. Nat. Protoc. 6, 961-78 (2011).
    • (2011) Nat. Protoc. , vol.6 , pp. 961-978
    • Seiler, A.E.M.1    Spielmann, H.2
  • 18
    • 77950862626 scopus 로고    scopus 로고
    • Three-dimensional tissue culture based on magnetic cell levitation
    • Souza, G. R., et al. Three-dimensional tissue culture based on magnetic cell levitation. Nat. Nanotechnol. 5, 291-6 (2010).
    • (2010) Nat. Nanotechnol. , vol.5 , pp. 291-296
    • Souza, G.R.1
  • 19
    • 77953215319 scopus 로고    scopus 로고
    • Invasive glioblastoma cells acquire stemness and increased Akt activation
    • Molina, J. R., Hayashi, Y., Stephens, C. & Georgescu, M.-M. Invasive glioblastoma cells acquire stemness and increased Akt activation. Neoplasia 12, 453-63 (2010).
    • (2010) Neoplasia , vol.12 , pp. 453-463
    • Molina, J.R.1    Hayashi, Y.2    Stephens, C.3    Georgescu, M.-M.4
  • 20
    • 84893140467 scopus 로고    scopus 로고
    • Estrogen eeceptor β of host promotes the progression of lung cancer brain metastasis of an orthotopic mouse model
    • Xu, L., Gao, G., Ren, J., Su, F. & Zhang, W. Estrogen eeceptor β of host promotes the progression of lung cancer brain metastasis of an orthotopic mouse model. J. Cancer Ther. 3, 352-8 (2012).
    • (2012) J. Cancer Ther. , vol.3 , pp. 352-358
    • Xu, L.1    Gao, G.2    Ren, J.3    Su, F.4    Zhang, W.5
  • 21
    • 84866539341 scopus 로고    scopus 로고
    • Detection of hydroxyapatite in calcified cardiovascular tissues
    • Lee, J. S., Morrisett, J. D. & Tung, C.-H. Detection of hydroxyapatite in calcified cardiovascular tissues. Atherosclerosis 224, 340-7 (2012).
    • (2012) Atherosclerosis , vol.224 , pp. 340-347
    • Lee, J.S.1    Morrisett, J.D.2    Tung, C.-H.3
  • 22
    • 84876166737 scopus 로고    scopus 로고
    • Effect of lyso-phosphatidylcholine and Schnurri-3 on osteogenic transdifferentiation of vascular smooth muscle cells to calcifying vascular cells in 3D culture
    • Castro-Chavez, F., Vickers, K. C., Lee, J. S., Tung, C.-H. & Morrisett, J. D. Effect of lyso-phosphatidylcholine and Schnurri-3 on osteogenic transdifferentiation of vascular smooth muscle cells to calcifying vascular cells in 3D culture. Biochim. Biophys. Acta 1830, 3828-34 (2013).
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 3828-3834
    • Castro-Chavez, F.1    Vickers, K.C.2    Lee, J.S.3    Tung, C.-H.4    Morrisett, J.D.5
  • 23
    • 84876824770 scopus 로고    scopus 로고
    • Adipose tissue engineering in three-dimensional levitation tissue culture system based on magnetic nanoparticles
    • Daquinag, A. C., Souza, G. R. & Kolonin, M. G. Adipose tissue engineering in three-dimensional levitation tissue culture system based on magnetic nanoparticles. Tissue Eng. Part C. Methods 19, 336-44 (2013).
    • (2013) Tissue Eng. Part C. Methods , vol.19 , pp. 336-344
    • Daquinag, A.C.1    Souza, G.R.2    Kolonin, M.G.3
  • 24
    • 84876827850 scopus 로고    scopus 로고
    • Using space-based investigations to inform cancer research on Earth
    • Becker, J. L. & Souza, G. R. Using space-based investigations to inform cancer research on Earth. Nat. Rev. Cancer 13, 315-27 (2013).
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 315-327
    • Becker, J.L.1    Souza, G.R.2
  • 25
    • 84885011867 scopus 로고    scopus 로고
    • Three-dimensional cell culturing by magnetic levitation
    • Haisler, W. L., et al. Three-dimensional cell culturing by magnetic levitation. Nat. Protoc. 8, 1940-9 (2013).
    • (2013) Nat. Protoc. , vol.8 , pp. 1940-1949
    • Haisler, W.L.1
  • 26
    • 84886286532 scopus 로고    scopus 로고
    • A high-throughput three-dimensional cell migration assay for toxicity screening with mobile device-based macroscopic image analysis
    • Timm, D. M., et al. A high-throughput three-dimensional cell migration assay for toxicity screening with mobile device-based macroscopic image analysis. Sci. Rep. 3, 3000 (2013).
    • (2013) Sci. Rep. , vol.3 , pp. 3000
    • Timm, D.M.1
  • 27
    • 84876838291 scopus 로고    scopus 로고
    • Assembly of a three-dimensional multitype bronchiole coculture model using magnetic levitation
    • Tseng, H., et al. Assembly of a three-dimensional multitype bronchiole coculture model using magnetic levitation. Tissue Eng. Part C. Methods 19, 665-75 (2013).
    • (2013) Tissue Eng. Part C. Methods , vol.19 , pp. 665-675
    • Tseng, H.1
  • 28
    • 84888606219 scopus 로고    scopus 로고
    • A three-dimensional co-culture model of the aortic valve using magnetic levitation
    • Tseng, H., et al. A three-dimensional co-culture model of the aortic valve using magnetic levitation. Acta Biomater. 10, 173-82 (2014).
    • (2014) Acta Biomater. , vol.10 , pp. 173-182
    • Tseng, H.1
  • 29
    • 84912131782 scopus 로고    scopus 로고
    • Three-dimensional in Vitro co-culture model of breast bumor using magnetic levitation
    • Jaganathan, H., et al. Three-dimensional In Vitro co-culture model of breast bumor using magnetic levitation. Sci. Rep. 4, 6468 (2014).
    • (2014) Sci. Rep. , vol.4 , pp. 6468
    • Jaganathan, H.1
  • 30
    • 84897096605 scopus 로고    scopus 로고
    • Scaffold-free formation of a millimeter-scale multicellular spheroid with an internal cavity from magnetically levitated 3T3 cells that ingested iron oxide-containing microspheres
    • Lee, J. H. & Hur, W. Scaffold-free formation of a millimeter-scale multicellular spheroid with an internal cavity from magnetically levitated 3T3 cells that ingested iron oxide-containing microspheres. Biotechnol. Bioeng. 111, 1038-47 (2014).
    • (2014) Biotechnol. Bioeng. , vol.111 , pp. 1038-1047
    • Lee, J.H.1    Hur, W.2
  • 31
    • 84882815407 scopus 로고    scopus 로고
    • High-throughput generation of spheroids using magnetic nanoparticles for three-dimensional cell culture
    • Kim, J. A., et al. High-throughput generation of spheroids using magnetic nanoparticles for three-dimensional cell culture. Biomaterials 34, 8555-63 (2013).
    • (2013) Biomaterials , vol.34 , pp. 8555-8563
    • Kim, J.A.1
  • 33
    • 84901749083 scopus 로고    scopus 로고
    • Advanced cell culture techniques for cancer drug discovery
    • Lovitt, C. J., Shelper, T. B. & Avery, V. M. Advanced cell culture techniques for cancer drug discovery. Biology (Basel). 3, 345-67 (2014).
    • (2014) Biology (Basel) , vol.3 , pp. 345-367
    • Lovitt, C.J.1    Shelper, T.B.2    Avery, V.M.3
  • 34
    • 1542373992 scopus 로고    scopus 로고
    • Fibronectin matrix assembly regulates alpha5beta1-mediated cell cohesion
    • Robinson, E. E., Foty, R. A. & Corbett, S. A. Fibronectin matrix assembly regulates alpha5beta1-mediated cell cohesion. Mol. Biol. Cell 15, 973-981 (2004).
    • (2004) Mol. Biol. Cell , vol.15 , pp. 973-981
    • Robinson, E.E.1    Foty, R.A.2    Corbett, S.A.3
  • 35
    • 84941717130 scopus 로고    scopus 로고
    • Guidance document on using in Vitro data to estimate
    • National Toxicology Program
    • National Toxicology Program. Guidance document on using In Vitro data to estimate In Vivo starting doses for acute toxicity. (2001).
    • (2001) In Vivo Starting Doses for Acute Toxicity
  • 36
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63 (1983).
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 37
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang, J.-H. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J. Biomol. Screen. 4, 67-73 (1999).
    • (1999) J. Biomol. Screen. , vol.4 , pp. 67-73
    • Zhang, J.-H.1
  • 38
    • 84855282492 scopus 로고    scopus 로고
    • Epigenetic regulation by RARα maintains ligand-independent transcriptional activity
    • Laursen, K. B., Wong, P. M. & Gudas, L. J. Epigenetic regulation by RARα maintains ligand-independent transcriptional activity. Nucleic Acids Res. 40, 102-115 (2012).
    • (2012) Nucleic Acids Res. , vol.40 , pp. 102-115
    • Laursen, K.B.1    Wong, P.M.2    Gudas, L.J.3
  • 40
    • 0034278085 scopus 로고    scopus 로고
    • The IAP family: Endogenous caspase inhibitors with multiple biological activities
    • Yang, Y. L. & Li, X. M. The IAP family: endogenous caspase inhibitors with multiple biological activities. Cell Res. 10, 169-77 (2000).
    • (2000) Cell Res. , vol.10 , pp. 169-177
    • Yang, Y.L.1    Li, X.M.2
  • 41
    • 0032080694 scopus 로고    scopus 로고
    • Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process
    • Gallagher, A. P., Burnett, A. K., Bowen, D. T. & Darley, R. L. Mutant RAS selectively promotes sensitivity of myeloid leukemia cells to apoptosis by a protein kinase C-dependent process. Cancer Res. 58, 2029-35 (1998).
    • (1998) Cancer Res. , vol.58 , pp. 2029-2035
    • Gallagher, A.P.1    Burnett, A.K.2    Bowen, D.T.3    Darley, R.L.4
  • 42
    • 0035712790 scopus 로고    scopus 로고
    • Effect of retinoic acid on the actin cytoskeleton in HL-60 cells
    • Zitterbart, K. & Veselsk, R. Effect of retinoic acid on the actin cytoskeleton in HL-60 cells. Neoplasma 48, 456-461 (2001).
    • (2001) Neoplasma , vol.48 , pp. 456-461
    • Zitterbart, K.1    Veselsk, R.2
  • 43
    • 0036847229 scopus 로고    scopus 로고
    • Gene expression regulation by retinoic acid
    • Balmer, J. E. & Blomhoff, R. Gene expression regulation by retinoic acid. J. Lipid Res. 43, 1773-1808 (2002).
    • (2002) J. Lipid Res. , vol.43 , pp. 1773-1808
    • Balmer, J.E.1    Blomhoff, R.2
  • 44
    • 17144429653 scopus 로고    scopus 로고
    • The challenge to measure cell proliferation in two and three dimensions
    • Ng, K. W., Leong, D. T. W. & Hutmacher, D. W. The challenge to measure cell proliferation in two and three dimensions. Tissue Eng. 11, 182-91 (2005).
    • (2005) Tissue Eng. , vol.11 , pp. 182-191
    • Ng, K.W.1    Leong, D.T.W.2    Hutmacher, D.W.3
  • 45
    • 0023188745 scopus 로고
    • Glucocorticoid regulation of beta-adrenergic receptors in 3T3-L1 preadipocytes
    • Nakada, M. T., Stadel, J. M., Poksay, K. S. & Crooke, S. T. Glucocorticoid regulation of beta-adrenergic receptors in 3T3-L1 preadipocytes. Mol. Pharmacol. 31, 377-84 (1987).
    • (1987) Mol. Pharmacol. , vol.31 , pp. 377-384
    • Nakada, M.T.1    Stadel, J.M.2    Poksay, K.S.3    Crooke, S.T.4
  • 46
    • 0027010262 scopus 로고
    • Activation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis
    • Varrault, A., Bockaert, J. & Waeber, C. Activation of 5-HT1A receptors expressed in NIH-3T3 cells induces focus formation and potentiates EGF effect on DNA synthesis. Mol. Biol. Cell 3, 961-9 (1992).
    • (1992) Mol. Biol. Cell , vol.3 , pp. 961-969
    • Varrault, A.1    Bockaert, J.2    Waeber, C.3
  • 47
    • 0031570091 scopus 로고    scopus 로고
    • Corticosteroids inhibit lymphocyte binding to endothelium and intercellular adhesion: An additional mechanism for their anti-inflammatory and immunosuppressive effect
    • Pitzalis, C., et al. Corticosteroids inhibit lymphocyte binding to endothelium and intercellular adhesion: an additional mechanism for their anti-inflammatory and immunosuppressive effect. J. Immunol. 158, 5007-16 (1997).
    • (1997) J. Immunol. , vol.158 , pp. 5007-5016
    • Pitzalis, C.1
  • 48
    • 13244255307 scopus 로고    scopus 로고
    • A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods
    • Yarrow, J. C., Perlman, Z. E., Westwood, N. J. & Mitchison, T. J. A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods. BMC Biotechnol. 4, 21 (2004).
    • (2004) BMC Biotechnol. , vol.4 , pp. 21
    • Yarrow, J.C.1    Perlman, Z.E.2    Westwood, N.J.3    Mitchison, T.J.4
  • 49
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell, C., Pachter, L. & Salzberg, S. L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-11 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 50
    • 77952123055 scopus 로고    scopus 로고
    • Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
    • Trapnell, C., et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol. 28, 511-5 (2010).
    • (2010) Nat. Biotechnol. , vol.28 , pp. 511-515
    • Trapnell, C.1
  • 51
    • 84872198346 scopus 로고    scopus 로고
    • Differential analysis of gene regulation at transcript resolution with RNA-seq
    • Trapnell, C., et al. Differential analysis of gene regulation at transcript resolution with RNA-seq. Nat. Biotechnol. 31, 46-53 (2013).
    • (2013) Nat. Biotechnol. , vol.31 , pp. 46-53
    • Trapnell, C.1


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