Three-dimensional tissue culture based on magnetic cell levitation

Nature Nanotechnology

Volumn 5, Issue 4, 2010, Pages 291-296

  Souza, Glauco R ^a,d   Molina, Jennifer R ^a   Raphael, Robert M ^b   Ozawa, Michael G ^a   Stark, Daniel J ^c   Levin, Carly S ^d   Bronk, Lawrence F ^a   Ananta, Jeyarama S ^c   Mandelin, Jami ^a   Georgescu, Maria Magdalena ^a   Bankson, James A ^a   Gelovani, Juri G ^a   Killian, T C ^c   Arap, Wadih ^a   Pasqualini, Renata ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b Rice University   (United States)

^c RICE UNIVERSITY   (United States)

^d Nano3D Biosciences Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL SIGNALING; GENE EXPRESSION; GOLD COMPOUNDS; HYDROGELS; IRON OXIDES; MAGNETIC LEVITATION; NANOMAGNETICS; PROTEINS; STEM CELLS; TISSUE; TISSUE CULTURE;

DRUG DISCOVERY; GLIOBLASTOMA CELLS; MAGNETIC IRON OXIDE NANOPARTICLES; PROTEIN EXPRESSION PROFILES; PROTEIN EXPRESSIONS; STEM CELL RESEARCH; THREE-DIMENSIONAL CULTURE; TUMOUR XENOGRAFTS;

CELL ENGINEERING;

IRON OXIDE; NERVE CELL ADHESION MOLECULE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIOPHAGE; CANCER CELL; CELL TYPE; COCULTURE; GEOMETRY; GLIOBLASTOMA; HUMAN; HUMAN CELL; HYDROGEL; IMMUNOFLUORESCENCE; INNER CELL MASS; INTRACRANIAL TUMOR; MAGNETIC FIELD; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUE CULTURE CELL; TUMOR XENOGRAFT;

EID: 77950862626     PISSN: 17483387     EISSN: 17483395     Source Type: Journal    
DOI: 10.1038/nnano.2010.23     Document Type: Article

References (30)

1. Cukierman, E., Pankov, R., Stevens, D. R. &Yamada, K. M. Taking cell-matrix adhesions to the third dimension. Science 294, 1708-1712 (2001).
2. Abbott, A. Biology's new dimension. Nature 424, 870-872 (2003).
3. Pampaloni, F., Reynaud, E. G. &Stelzer, E. H. The third dimension bridges the gap between cell culture and live tissue. Nature Rev. Mol. Cell Biol. 8, 839-845 (2007).
4. Griffith, L. G. &Swartz, M. A. Capturing complex 3D tissue physiology in vitro. Nature Rev. Mol. Cell Biol. 7, 211-224 (2006).
5. Atala, A. Engineering tissues, organs and cells. J. Tissue Eng. Regen. Med. 1, 83-96 (2007).
6. Coleman, C. B. et al. Diamagnetic levitation changes growth, cell cycle and gene expression of Saccharomyces cerevisiae. Biotechnol. Bioeng. 98, 854-863 (2007).
7. Dobson, J. Remote control of cellular behaviour with magnetic nanoparticles. Nature Nanotech. 3, 139-143 (2008).
8. Ito, A., Shinkai, M., Honda, H. &Kobayashi, T. Medical application of functionalized magnetic nanoparticles. J. Biosci. Bioeng. 100, 1-11 (2005).
9. Souza, G. R. et al. Networks of gold nanoparticles and bacteriophage as biological sensors and cell targeting agents. Proc. Natl Acad. Sci. USA 103, 1215-1220 (2006).
10. Souza, G. R. et al. Bottom-up assembly of hydrogels from bacteriophage and Au nanoparticles: the effect of cis- and trans-acting factors. PLoS ONE 3, e2242 (2008).
11. Petersen, O. W., Ronnov-Jessen, L., Howlett, A. R. &Bissell, M. J. Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. Proc. Natl Acad. Sci. USA 89, 9064-9068 (1992).
12. Mikos, A. G. et al. Engineering complex tissues. Tissue Eng. 12, 3307-3339 (2006).
13. Ito, A., Ino, K., Kobayashi, T. &Honda, H. The effect of RGD peptideconjugated magnetite cationic liposomes on cell growth and cell sheet harvesting. Biomaterials 26, 6185-6193 (2005).
14. Pankhurst, Q., Connolly, J., Jones, S. K. &Dobson, J. Applications of magnetic nanoparticles in biomedicine. J. Phys. D 36, R167-R181 (2003).
15. Alsberg, E., Feinstein, E., Joy, M. P., Prentiss, M. &Ingber, D. E. Magneticallyguided self-assembly of fibrin matrices with ordered nano-scale structure for tissue engineering. Tissue Eng. 12, 3247-3256 (2006).
16. Dobson, J., Cartmell, S. H., Keramane, A. &El Haj, A. J. Principles and design of a novel magnetic force mechanical conditioning bioreactor for tissue engineering, stem cell conditioning and dynamic in vitro screening. IEEE Trans. Nanobiosci. 5, 173-177 (2006).
17. Meyer, C. J. et al. Mechanical control of cyclic AMP signaling and gene transcription through integrins. Nature Cell Biol. 2, 666-668 (2000).
18. Matthews, B. D., La Van, D. A., Overby, D. R., Karavitis, J. &Ingber, D. E. Electromagnetic needles with submicron pole tip radii for nanomanipulation for biomolecules and living cells. Appl. Phys. Lett. 85, 2968-2970 (2004).
19. Arap, W., Pasqualini, R. &Ruoslahti, E. Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model. Science 279, 377-380 (1998).
20. Hajitou, A. et al. A hybrid vector for ligand-directed tumor targeting and molecular imaging. Cell 125, 385-398 (2006).
21. Nam, K. T. et al. Virus-enabled synthesis and assembly of nanowires for lithium ion battery electrodes. Science 312, 885-888 (2006).
22. Langer, R. &Tirrell, D. A. Designing materials for biology and medicine. Nature 428, 487-492 (2004).
23. Hautot, D. et al. Preliminary observation of elevated levels of nanocrystalling iron oxide in the basal ganglia of neuroferritinopathy patients. Biochim. Biophys. Acta 1772, 21-25 (2007).
24. Snyder, E. Y. et al. Multipotent neural cell lines can engraft &participate in development of mouse cerebellum. Cell 68, 33-51 (1992).
25. Wan, X., Li, Z. &Lubkin, S. R. Mechanics of mesenchymal contribution to clefting force in branching morphogenesis. Biomech. Model. Mechanobiol. 7, 417-426 (2008).
26. Csikasz-Nagy, A., Battogtokh, D., Chen, K. C., Novak, B. &Tyson, J. J. Analysis of a generic model of eukaryotic cell-cycle regulation. Biophys. J. 90, 4361-4379 (2006).
27. Ofek, G. et al. Matrix development in self-assembly of articular cartilage. PLoS ONE 3, e2795 (2008).
28. Bhowmick, D. A., Zhuang, Z., Wait, S. D. &Weil, R. J. A functional polymorphism in the EGF gene is found with increased frequency in glioblastoma multiforme patients and is associated with more aggressive disease. Cancer Res. 64, 1220-1223 (2004).
29. Chicoine, M. R. &Silbergeld, D. L. Mitogens as motogens. J. Neurooncol. 35, 249-257 (1997).
30. Georgescu, M. M., Kirsch, K. H., Akagi, T., Shishido, T. &Hanafusa, H. The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc. Natl Acad. Sci. USA 96, 10182-10187 (1999).