Biodistribution and efficacy of targeted pulmonary delivery of a protein kinase C-δ inhibitory peptide: Impact on indirect lung injury

Journal of Pharmacology and Experimental Therapeutics

Volumn 355, Issue 1, 2015, Pages 86-98

  Mondrinos, Mark J ^a   Knight, Linda C ^a   Kennedy, Paul A ^a   Wu, Jichuan ^a   Kauffman, Matthew ^a   Baker, Sandy T ^a   Wolfson, Marla R ^a   Kilpatrick, Laurie E ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE; SERYLPHENYLALANYLASPARGINYLSERYLTYROSINYLGLUTAMYLLEUCYLGLYCYLSERYLLEUCINE; TETRAMETHYLRHODAMINE; TYROSINYLGLYCYLARGINYLLYSYLLYSYLARGINYLARGINYLGLUTAMINYLARGINYLARGINYLARGININE; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; PEPTIDE FRAGMENT; PROTEIN KINASE C DELTA; PROTEIN KINASE INHIBITOR; TECHNETIUM; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BLOOD; CELL TRANSPORT; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; ENZYME ACTIVATION; FLUORESCENCE; GENE TRANSLOCATION; HISTOPATHOLOGY; ISOTOPE LABELING; KIDNEY; LIVER; LUNG; LUNG FUNCTION; LUNG GAS EXCHANGE; LUNG INJURY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN PHOSPHORYLATION; RAT; SKELETAL MUSCLE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; MICROBIOLOGY; PATHOLOGY; PATHOPHYSIOLOGY; PNEUMONIA; SEPSIS; SPRAGUE DAWLEY RAT; TISSUE DISTRIBUTION; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL TRANSPORT; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE PRODUCTS, TAT; LUNG; LUNG INJURY; MALE; PEPTIDE FRAGMENTS; PNEUMONIA; PROTEIN KINASE C-DELTA; PROTEIN KINASE INHIBITORS; PULMONARY GAS EXCHANGE; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; TECHNETIUM; TISSUE DISTRIBUTION;

EID: 84941687080     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.115.224832     Document Type: Article

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